Clinical Trials on Necrosis in United Kingdom

Total 1123 results

Sheffield Teaching Hospitals NHS Foundation Trust

Suspended

Development of Novel Physiological CMR Methods in Health and Disease

Myocardial Infarction | Coronary Artery Disease | Heart Failure | Pulmonary Hypertension

United Kingdom
University of Edinburgh
University of Nottingham; British Heart Foundation

Completed

LACunar Intervention (LACI-2) Trial-2 (LACI-2)

Cerebral Small Vessel Diseases | Stroke, Lacunar

United Kingdom
Imperial College London

Completed

Autologous Bone Marrow Stem Cells in Ischemic Stroke.

Infarction, Middle Cerebral Artery | Stroke, Acute

United Kingdom
Jozef Bartunek
King's College London

Terminated

A Trial Using CD133 Enriched Bone Marrow Cells Following Primary Angioplasty for Acute Myocardial Infarction (SELECT-AMI)

Acute Myocardial Infarction

Netherlands, France, Belgium, United Kingdom
University of Nebraska

Completed

The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth

Pulpal Necrosis

United States
DePuy International

Terminated

A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom, Italy
NHS Greater Glasgow and Clyde
National Institute for Health Research, United Kingdom; University of Glasgow

Completed

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI (T-TIME)

Myocardial Infarction

United Kingdom
University of Oxford

Recruiting

The Short and Long-term Cardiovascular Consequences of Critical Illness: The C3 Study (C3)

Myocardial Infarction | Stroke | Critical Illness | Atrial Flutter | Atrium; Fibrillation

United Kingdom
Hull University Teaching Hospitals NHS Trust

Completed

Assessing the Efficacy of CardiOGoniometry (CGM) to Localise the Culprit Vessel in Mixed Vessel Disease Non-ST elevatIon Myocardial infarcTION (NSTEMI) (COGNITION)

Acute Coronary Syndrome

United Kingdom
Washington University School of Medicine
University of Oklahoma Medical Center; Northwestern University Chicago Illinois and other collaborators

Completed

Rad Predictors for WON

Walled Off Pancreatic Necrosis (WON)

United States
Philips Healthcare

Completed

The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III

Myocardial Infarction | Renal Failure | Cardiac Arrest | Severe Sepsis | Respiration Failure

United Kingdom
AstraZeneca

Completed

Patient Characteristics, Persistence to Treatment and Outcome Events in Patients Treated With Ticagrelor 60 mg After Myocardial Infarction in Real-world Clinical Practice (ALETHEIA)

Myocardial Infarction (MI)

Sweden, United Kingdom, United States, Italy, Germany
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Traumatic Femoral Fractures

United Kingdom, Germany, Italy, Spain
Stryker Trauma GmbH

Completed

Aequalis Pyrocarbon IDE; Replacing the Humeral Head in Hemi-Arthroplasty (PYC)

Osteoarthritis | Avascular Necrosis | Traumatic Arthritis

United States
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Wolfson Brain Imaging...

Recruiting

Cambridge 7 Tesla Cerebral Small Vessel Disease Study (CamSVD)

Cerebral Small Vessel Diseases | Cerebral Small Vessel Ischemic Disease | Lacunar Stroke

United Kingdom
London School of Hygiene and Tropical Medicine
University College, London

Completed

Natural Ischaemic Preconditioning Before First Myocardial Infarction

Myocardial Infarction | Peripheral Arterial Disease | Angina Pectoris | Coronary Heart Disease | Cerebrovascular Disease

United Kingdom
The Cleveland Clinic
Biocomposites Ltd

Recruiting

The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head (Genex)

Osteonecrosis | Avascular Necrosis

United States
Boston Scientific Corporation

Completed

AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study

Walled Off Pancreatic Necrosis

United States
Biomet Orthopedics, LLC

Completed

A Clinical Investigation of the Oxford® Meniscal Unicompartmental Knee System

Osteoarthritis | Avascular Necrosis

United States
Barts & The London NHS Trust
University College, London; Queen Mary University of London

Completed

Bone Marrow Derived Adult Stem Cells for Acute Anterior Myocardial Infarction (REGEN-AMI)

Acute Myocardial Infarction

Switzerland, Denmark, United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; University Hospital Southampton... and other collaborators

Recruiting

Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection (INTERCEPT:GP)

Stroke | Neurocognitive Dysfunction | Silent Cerebral Infarction | Vascular Brain Injury

United Kingdom
Zimmer Biomet

Active, not recruiting

Biologically Assisted Core Decompression of the Femoral Head Using the PerFuse Instrument and BioCUE (REGP-44-00)

Avascular Necrosis of the Femoral Head

United States
Kenneth Hargreaves
University of Maryland, Baltimore; Loma Linda University; University of North... and other collaborators

Completed

Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots

Regeneration | Pulp Necrosis

United States
Paragon 28

Recruiting

Patient Specific Talus Spacer Post Approval Study

Avascular Necrosis of the Talus

United States
University of Michigan

Completed

Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease

Focal Segmental Glomerulosclerosis | Minimal Change Disease | FSGS | MCD

United States
Imperial College London

Recruiting

Glucose Control Using Continuous Glucose Monitoring in People With Type 2 Diabetes Who Have Had Acute Myocardial Infarct (GLAM)

Diabetes Complications | Type 2 Diabetes | Acute Myocardial Infarction | Acute Myocardial Infarction With ST Elevation

United Kingdom
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke

Acute Ischemic Stroke (AIS)

Netherlands, Finland, United Kingdom
University Hospitals Coventry and Warwickshire...
University Hospitals of North Midlands NHS Trust

Completed

Validation of a Purine Biosensor in Detecting Acute Cerebral Ischaemia: Carotid Endarterectomy Model in SMARTChip (CEMS)

Stroke

United Kingdom
Erasmus Medical Center

Completed

PULsecath mechanicaL Support Evaluation (PULSE)

Coronary Artery Disease | Heart Failure | Cardiogenic Shock

France, Netherlands, United Kingdom
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Australia, Germany, United Kingdom
University College, London
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Myocardial Infarction | Heart Failure | Stroke | Peripheral Arterial Disease | Atrial Fibrillation | Bleeding | Coronary Heart Disease | Stable Angina | Death, Sudden, Cardiac

United Kingdom
Zimmer Biomet

Terminated

Avascular Necrosis (AVN) Long-Term Follow-up

Avascular Necrosis | Femoral Head Collapse

United States
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

INTERvention With Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation (INTERCEPTavi) (INTERCEPTavi)

Stroke | Aortic Valve Stenosis | Silent Cerebral Infarct | Vascular Brain Injury

United Kingdom
University of Edinburgh
British Heart Foundation

Completed

In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer (iThrombus)

Myocardial Infarction | Stroke | Thrombosis | Transient Ischemic Attack | Pulmonary Embolism | STEMI | NSTEMI - Non-ST Segment Elevation MI | DVT | PET | Atherothrombosis | Prosthetic Valve Thrombosis

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust

Completed

The Effect of IV Cangrelor and Oral Ticagrelor Study

ST-segment Elevation Myocardial Infarction (STEMI) | Acute Coronary Syndrome (ACS) | Unstable Angina (UA) | High On-treatment Platelet Reactivity (HTPR) | Microvascular Obstruction (MVO) | Thrombolysis in Myocardial Infarction (TIMI)

United Kingdom
Norton Healthcare
University of Kentucky

Completed

Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI) (LIBERTI)

Radiation Necrosis

United States
Dartmouth-Hitchcock Medical Center

Terminated

Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents

Pancreatic Necrosis

United States
Zimmer Biomet

Recruiting

Avenir Complete Post-Market Clinical Follow-Up Study

Osteoarthritis, Hip | Avascular Necrosis of Hip | Post-traumatic; Arthrosis | Avascular Necrosis of the Femoral Head

United States, Denmark, Japan, Netherlands, Norway, Sweden
Interscope, Inc.

Completed

EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial

Acute Pancreatitis | Necrotizing Pancreatitis | Acute Pancreatic Necrosis

United States, Netherlands, Germany
H. Lundbeck A/S

Completed

Safety and Pharmacokinetic Study of Carbamylated Erythropoietin (CEPO) to Treat Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

France, Netherlands, United Kingdom, Finland, Singapore
H. Lundbeck A/S

Completed

Safety Study of Carbamylated Erythropoietin (CEPO) to Treat Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

Finland, France, Netherlands, Singapore, United Kingdom
Zimmer Biomet

Active, not recruiting

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Revision Total Shoulder Arthroplasty | Ununited Humeral Head Fracture | Irreducible 3-and 4-part Proximal Humeral Fractures | Gross Rotator Cuff Deficiency

United States, United Kingdom
NYU Langone Health

Terminated

Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus Erythematosus

Avascular Necrosis

United States
Encore Medical, L.P.

Terminated

Efficacy of the CLP® Hip - Retrospective

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis

United States
University College, London
Wellcome Trust

Unknown

Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study

ST Elevation Myocardial Infarction | Stable Angina | Unstable Angina | Non ST Elevation Myocardial Infarction | Myocardial Infarction Not Otherwise Specified

United Kingdom
CellProthera

Completed

EXCELLENT (EXpanded CELL ENdocardiac Transplantation) (EXCELLENT)

Acute Myocardial Infarction

France, United Kingdom
NHS National Waiting Times Centre Board
University of Glasgow

Completed

Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome (CABG-ACS)

Unstable Angina | Non ST Elevation Myocardial Infarction

United Kingdom
Indiana University School of Medicine
VA Office of Research and Development

Withdrawn

Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty:

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis

United States
LumiraDx UK Limited

Completed

Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL) (OPTIMAL)

Atrial Fibrillation | Thrombophilia | Deep Vein Thrombosis | Antiphospholipid Syndrome | Pulmonary Embolism | Post-Myocardial Infarction Syndrome | Artificial Heart Device User

United Kingdom
University of Nottingham
National Institute for Health Research, United Kingdom

Completed

Validation and Reliability Testing of Dysphagia Trained Nurse Assessment

Dysphagia Following Cerebral Infarction | Dysphagia Following Nontraumatic Intracerebral Hemorrhage

United Kingdom

Clinical Trials on Necrosis in United Kingdom

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