Clinical Trials on Nematode Infections

Total 56683 results

London School of Hygiene and Tropical Medicine
Emory University; Imperial College London; Kenya Medical Research Institute; Kenya...

Completed

Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya (TUMIKIA)

Helminthiasis | Disease Transmission, Infectious | Nematode Infection

Kenya
IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

Schistosoma Mansoni

Italy
National Institute of Allergy and Infectious Diseases...

Completed

Study of Patients With Strongyloides Stercoralis Infection

HIV Infection | Strongyloidiasis | Nematode Infection

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis

Schistosomiasis
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia

Completed

Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi_KH)

Strongyloides Stercoralis Infection

Cambodia
Brugmann University Hospital
Université Libre de Bruxelles

Active, not recruiting

Hookworm Immune Regulation Project (HIRP-01)

Hookworm Infection

Vietnam
Swiss Tropical & Public Health Institute
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of a New Chewable Versus the Swallowable Tablet of Mebendazole Against Hookworm (CHEW_MEB_PEMBA)

Hookworm Infections

Tanzania
Baylor College of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); George Washington...

Active, not recruiting

Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection

Hookworm Infections

United States
Alejandro Krolewiecki
Brock University; Universidad Nacional del Centro de la Provincia de Buenos... and other collaborators

Completed

Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients (HI4T)

Helminthiasis | Trichuris Infection

Argentina, Honduras
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; National Institute of Public Health, Vientiane, Laos

Enrolling by invitation

Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi)

Strongyloides Stercoralis Infection

Cambodia, Lao People's Democratic Republic
Johns Hopkins Bloomberg School of Public Health
Universidad Peruana Cayetano Heredia

Withdrawn

Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults

Helminthiasis
IRCCS Sacro Cuore Don Calabria di Negrar

Completed

The SsRI/NIE Recombinant Antigen ELISA for the Follow up of Patients Infected by Strongyloides Stercoralis

Strongyloides Stercoralis Infection

Italy
IRCCS Sacro Cuore Don Calabria di Negrar
World Health Organization; Universidad Central del Ecuador; CECOMET (Centro de...

Completed

Evaluation of Strongyloidiasis in Ecuador: a fieLd Laboratory Accuracy Study (ESTRELLA)

Strongyloidiasis | Strongyloides Stercoralis Infection

Ecuador
Swiss Tropical & Public Health Institute
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris Trichiura (MOXIDOSE)

Trichuris Trichiura; Infection

Tanzania
Swiss Tropical & Public Health Institute
National Institute of Public Health, Vientiane, Laos

Not yet recruiting

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

Strongyloidiasis | Strongyloides Stercoralis Infection
Universidad Nacional de Salta
Albert B. Sabin Vaccine Institute; Fundacion Mundo Sano

Unknown

Management of Soil-transmitted Helminthiasis and Strongyloidiasis

Helminthiasis | Strongyloides Stercoralis Infection

Argentina
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm

Hookworm Infections

Tanzania
Albert B. Sabin Vaccine Institute
London School of Hygiene and Tropical Medicine; George Washington University; Oswaldo Cruz Foundation

Terminated

Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults

Hookworm Infection

Brazil
Imperial College Healthcare NHS Trust

Unknown

Strongyloides Stercoralis in Bone Marrow Transplant Recipients in the UK (SSSSBMTUK)

Strongyloidiasis | Bone Marrow Transplant Infection
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Recruiting

Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC (Iverped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
PATH
Yale University; Ghana Health Services; Kintampo Health Research Centre, Ghana; Noguchi Memorial Institute for Medical Research and other collaborators

Withdrawn

Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana

Hookworm Infections

Ghana
Albert Einstein College of Medicine

Terminated

Treatment of Strongyloides Infection (TSSI)

Strongyloidiasis | Strongyloides Stercoralis Infection

United States
Leiden University Medical Center

Completed

Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center (CHHIL)

Necator Americanus Infection

Netherlands
Meta Roestenberg

Completed

Repeated Controlled Human Hookworm Infection (ReCHHI1)

Necator Americanus Infection

Netherlands
Oxfendazole Development Group
Universidad Peruana Cayetano Heredia, Lima, Peru

Not yet recruiting

Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults

Trichuris Infection
Baylor College of Medicine

Recruiting

Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

Hookworm Infection

United States
Swiss Tropical & Public Health Institute

Completed

Triple Combinations Against Hookworm Infections in Lao (Tricombi)

Hookworm Infection

Lao People's Democratic Republic
Baylor College of Medicine
Bill and Melinda Gates Foundation

Completed

Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection

Hookworm Infection

United States
IRCCS Sacro Cuore Don Calabria di Negrar

Not yet recruiting

Preliminary Evaluation of Two Rapid Diagnostic Test Prototypes for Strongyloides Stercoralis Infection (PROTOSS)

Strongyloides Stercoralis Infection

Italy
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Active, not recruiting

Efficacy and Safety of MOX/ALB Co-administration in SAC (Moxiped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Leiden University Medical Center

Completed

Immunisation, Treatment and Controlled Human Hookworm Infection (ITCHHI)

Necator Americanus Infection

Netherlands
Baylor College of Medicine

Completed

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Hookworm Infection | Hookworm Disease

Gabon
Baylor College of Medicine
Johns Hopkins University; University of California, San Francisco; George Washington... and other collaborators

Completed

Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults

Hookworm Infection | Hookworm Disease

Brazil
George Washington University
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults

Trichuriasis | Whipworm | Controlled Human Infection

United States
University Hospitals Cleveland Medical Center
Washington University School of Medicine

Completed

Pharmacokinetics & Pharmacodynamics of Diethylcarbamazine (DEC)+ Albendazole (ALB) + Ivermectin (IVE)

Wuchereria Bancrofti Infection

Côte D'Ivoire
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Albendazole Dose Finding and Pharmacokinetics in Children and Adults

Hookworm Infections | Trichuriasis

Côte D'Ivoire
University Ghent
VLIR-UOS Institutional University Cooperation

Completed

The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia

Infection by Trichuris Trichiura

Ethiopia
Albert B. Sabin Vaccine Institute

Completed

Development of a Skin Test for the Na-ASP-2 Hookworm Antigen

Allergy | Hookworm Infection

United States
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm (EMODEP_PEMBA)

Hookworm Infections | Trichuris Trichiura; Infection

Tanzania
Bird, Christopher
London School of Hygiene and Tropical Medicine; Fondazione Ivo de Carneri,...

Completed

Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar (SKIP)

Hookworm

Tanzania
Albert B. Sabin Vaccine Institute

Completed

Prevalence of Hookworm Infection and Community Preparedness for Hookworm Vaccine Trials in Endemic Areas of Brazil

Hookworm Infection

Brazil
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Efficacy and Safety of MOX/ALB Co-administration

Hookworm Infections | Ascariasis | Trichuriasis

Côte D'Ivoire
Universitas Sumatera Utara

Unknown

Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education

Helminthiasis | Children, Only | Hookworm Infections | Trichuris Infection | Ascaris Infection

Indonesia
University Ghent
University of Nottingham; George Washington University; World Health Organization and other collaborators

Completed

A Multinational Trial of the Efficacy of Albendazole Against Soil-transmitted Nematode Infections in Children (WORMCON)

Infections With Soil-Transmitted Helminths (STH)

Cambodia, Vietnam, Brazil, Cameroon, Ethiopia, India, Tanzania
Stanford University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Cement flooRs AnD chiLd hEalth (CRADLE)

Diarrhea | Necator Americanus Infection | Ascaris Lumbricoides Infection | Trichuris Trichiura; Infection

Bangladesh
National Institute of Allergy and Infectious Diseases...

Completed

Changes in HIV Viral Load in Patients Undergoing Treatment for Filariasis

HIV Infections | Filarial Infection

India
Centers for Disease Control and Prevention
Universidad del Valle, Guatemala

Completed

Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections

Pediculosis | Strongyloidiasis | Ascariasis | Trichuriasis | Hookworm Infection

Guatemala
Jennifer Keiser
Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health...

Completed

Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura (FACEITeffic)

Trichuriasis

Uganda
Jennifer Keiser
Lao Tropical and Public Health Institute; Centre Suisse de Recherches Scientifiques... and other collaborators

Completed

Efficacy and Safety of IVM/ALB Co-administration

Trichuriasis

Côte D'Ivoire, Tanzania, Lao People's Democratic Republic
Centro per le Malattie Tropicali
European Commission

Completed

Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis (STRONGTREAT)

Strongyloidiasis

Italy, Spain, United Kingdom

Clinical Trials on Nematode Infections

Sponsors and Collaborators

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CROs by country

CROs in Burundi

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Rare Diseases

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