Clinical Trials on Neonates or Premature Babies in South Africa

Total 61 results

University of Stellenbosch
Stanford University

Completed

Transcutaneous Screening for Risk of Severe Hyperbilirubinemia in South African Newborns

Hyperbilirubinemia | Neonatal Jaundice

South Africa
Mednax Center for Research, Education, Quality...

Completed

Dose Comparison of Amino Acids on Growth in Premature Neonates

Malnutrition

United States
University of Stellenbosch
Fogarty International Center of the National Institute of Health

Unknown

Neonatal Bacterial Colonization Study

Prematurity | Bloodstream Infection | Neonatal SEPSIS | Very Low Birth Weight Baby

South Africa
Pediatrix

Completed

Amino Acid and Acylcarnitine Profiles in Premature Neonates

Prematurity | Parenteral Nutrition | Neonatal Screening

United States
Drugs for Neglected Diseases
Universiteit Antwerpen; PENTA Foundation; St George's, University of London

Completed

NeoAMR Observational Study in Neonatal Sepsis

Neonatal SEPSIS

Bangladesh, Uganda, Thailand, South Africa, Italy, Greece, India, Brazil, China, Kenya, Vietnam
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Philips Healthcare
Memorial Hospital of South Bend

Withdrawn

Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB

Stress | Preterm Birth | Growth Acceleration | Chronic Lung Disease | Satisfaction | Adverse Event | Low; Birthweight, Extremely (999 Grams or Less) | Neonatal Infection

United States
Mednax Center for Research, Education, Quality...

Completed

Registry for Severe ROP and Treatment on Visual Outcomes

Retinopathy of Prematurity

United States
Brno University Hospital
Masaryk University

Active, not recruiting

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Perioperative Analgesia in Neonates

Czechia
University of Alberta

Completed

Acupuncture for Preterm Infants Requiring Eye-exam (MAGNIFIC-ROP)

Pain | Retinopathy of Prematurity | Acupuncture | Premature Infant

Canada, Australia, Malaysia
Cardiff and Vale University Health Board
Cardiff University

Recruiting

nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis (nSeP)

Sepsis

United Kingdom
The University of Texas Health Science Center,...

Unknown

Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity (BEAT-ROP)

Retinopathy of Prematurity

United States
Spark Biomedical, Inc.
Medical University of South Carolina; University of Texas Southwestern Medical...

Recruiting

Neurostimulation to Improve NOWS Outcomes (SPROUT)

Neonatal Abstinence Syndrome | Neonatal Opioid Withdrawal Syndrome

United States
Medical University of South Carolina

Completed

Intrapartum Study of Sterile and Clean Gloves

Chorioamnionitis

United States
Spark Biomedical, Inc.
Medical University of South Carolina

Completed

tAN to Mitigate Withdrawal Behaviors in Neonates

Neonatal Abstinence Syndrome

United States
Monash University
National Health and Medical Research Council, Australia; Cerebral Palsy Alliance and other collaborators

Recruiting

Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction (PROTECTMe)

Fetal Growth Retardation | Pregnancy Preterm | Stillbirth and Fetal Death

Australia, New Zealand
National Eye Institute (NEI)

Completed

Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity

Retinopathy of Prematurity

United States
National Eye Institute (NEI)

Unknown

The Early Treatment for Retinopathy of Prematurity Study (ETROP)

Retinopathy of Prematurity

United States
InfaCare Pharmaceuticals Corporation, a Mallinckrodt...

Completed

Stannsoporfin With Light Therapy for Newborn Babies With Jaundice (JASMINE_204)

Hyperbilirubinemia, Neonatal | Jaundice, Neonatal

United States
Leiden University Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Sanquin...

Recruiting

PRedicting OutcomeS in Preterm nEonates With thromboCyTopenia (PROSPECT) (PROSPECT)

Intraventricular Hemorrhage | Neonatal Thrombocytopenia | Platelet Transfusion

Netherlands, Sweden
University of Athens
University of Thessaly

Completed

Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure (HFO-TGI-2)

Respiratory Distress Syndrome

Greece
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Terminated

A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP (ROP3)

Retinopathy of Prematurity

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

Bevacizumab Treatment For Type 1 ROP (ROP4)

Retinopathy of Prematurity

United States, Canada
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)

Brain Injury | Chorioamnionitis

United States
University of Athens

Completed

Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome

Respiratory Distress Syndrome, Adult

Greece
Murdoch Childrens Research Institute
University of Pennsylvania; University of Oxford; Academisch Medisch Centrum...

Recruiting

Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial). (POLAR)

Preterm Birth | Lung Injury

United States, Australia, Austria, Italy, Netherlands, United Kingdom, Poland, France
Oak Hill Bio Ltd

Terminated

Safety and Efficacy Outcomes Following Previously Administered Short-Term Treatment With SHP607 in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

United States, Italy, United Kingdom
University of Athens
University of Thessaly

Terminated

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome

Greece
University of Athens

Completed

Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO

Acute Respiratory Distress Syndrome | Acute Cor Pulmonale

Greece
Prisma Health-Midlands

Withdrawn

N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome (NARDS)

Acute Respiratory Distress Syndrome

United States
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
Draeger Medical Systems, Inc.

Unknown

Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates

Respiratory Distress Syndrome In Premature Infants

United States
University of Athens

Recruiting

Cerebral Autoregulation and COVID-19 (CA-COVID)

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Greece
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study (MOMs-CMA)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
Aerogen Pharma Limited

Active, not recruiting

A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact

Respiratory Distress Syndrome in Premature Infant

United States, Canada
OHB Neonatology Ltd.

Active, not recruiting

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Chronic Lung Disease in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

United States, United Kingdom, Italy, France, Germany, Netherlands, Finland, Japan, Portugal, Canada, Ireland, Spain, Sweden
MedImmune LLC

Completed

Study of Motavizumab (MEDI-524) and Palivizumab Administered Sequentially in the Same Respiratory Syncytial Virus (RSV) Season

Respiratory Syncytial Virus Infections | Chronic Lung Disease and <= 24 Months of Age or | Premature With Gestational Age <=35 Weeks and <=6 Months of Age

Australia, Chile, New Zealand
Mucpharm Pty Ltd
St George Hospital, Australia; Mobius Medical Pty Ltd.

Completed

Nebulised BromAc in Healthy Volunteers

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome | Bromelains Adverse Reaction | Acetylcysteine Adverse Reaction | Mucus; Plug

Australia
University of Sydney
University of Pennsylvania; University of California, San Diego; University of... and other collaborators

Completed

Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis (NeOProM)

Infant, Newborn, Diseases | Infant, Premature, Diseases | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Infant, Very Low Birth Weight

Australia
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD)

Bronchopulmonary Dysplasia

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

Lung Diseases | Bronchopulmonary Dysplasia

United States
Mallinckrodt

Completed

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

Bronchopulmonary Dysplasia

United States, Canada
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
Cynata Therapeutics Limited
Cerebral Palsy Alliance

Completed

The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause (MEND)

Covid19 | Acute Respiratory Distress Syndrome

Australia
ONY

Completed

Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients

Respiratory Distress Syndrome

United States
Roberta Ballard
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia (TOLSURF)

Bronchopulmonary Dysplasia

United States
Chiesi Farmaceutici S.p.A.

Completed

A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)

Respiratory Distress Syndrome, Newborn

United States
Australian and New Zealand Intensive Care Research...
The Alfred

Not yet recruiting

Trial of ECMO to De-Sedate, Extubate Early and Mobilise in Hypoxic Respiratory Failure (REDEEM)

Pneumonia | Extracorporeal Membrane Oxygenation | Mechanical Ventilation Complication | Hypoxemia | COVID-19 Respiratory Infection | Acute Respiratory Distress Syndrome Due to COVID-19

Australia, Germany

Clinical Trials on Neonates or Premature Babies in South Africa

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