Clinical Trials on Neoplasm Metastasis in Germany

Total 6260 results

AIO-Studien-gGmbH
Servier

Completed

Nal-IRI and 5-FU Compared to 5-FU in Patients With Cholangio- and Gallbladder Carcinoma Previously Treated With Gemcitabine-based Therapies (NALIRICC)

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma of the Gallbladder | Cholangiocarcinoma Metastatic | Cholangiocarcinoma Advanced

Germany
PD Dr. med. Volker Heinemann
University of Cologne; Technical University of Munich

Unknown

Afatinib and Gemcitabine/Nab-paclitaxel in Metastatic Pancreatic Cancer (AFFECT)

Metastatic Pancreatic Cancer

Germany
CONKO-Studiengruppe
Eli Lilly and Company

Completed

Gemcitabine (GFF) in Patients With Pancreatic Cancer (GFF)

Metastatic Pancreatic Cancer

Germany
BioInvent International AB

Active, not recruiting

BI-1607 in Combination With Trastuzumab in Subjects With HER2-positive Advanced Solid Tumors (CONTRAST)

HER2-positive Breast Cancer | HER2-positive Gastric Cancer | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | HER2-positive Metastatic Breast Cancer

Spain, United Kingdom, Germany
Spectrum Pharmaceuticals, Inc

Completed

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Metastatic Cancer

France, United States, Canada, Belgium, Italy, Australia, United Kingdom, Germany, Hungary
AIO-Studien-gGmbH
Novartis Pharmaceuticals; iOMEDICO AG

Completed

Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs. Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast Cancer (VicTORia)

Her2-negative Metastatic Breast Cancer | Her2-negative Locally Advanced Breast Cancer

Germany
Merck KGaA, Darmstadt, Germany

Completed

A Study to Determine the Safety, Tolerability, Pharmacokinetics and Dynamic Effects of Different Doses of the Study Drug EMD 525797 in Prostate Cancer

Prostate Cancer | Bone Metastases

Belgium, Germany
iOMEDICO AG

Completed

Non-interventional Study With Nab-Paclitaxel (Abraxane®) (NABUCCO)

Metastatic Breast Cancer

Germany
Oncoscience AG
University of Kiel; Marienhospital Herne; Gemeinschaftspraxis für Hämatologie... and other collaborators

Completed

Nimotuzumab in Adults With Pancreatic Cancer

Pancreatic Cancer, Advanced or Metastatic

Germany
Hasumi International Research Foundation

Active, not recruiting

IKKb-matured, RNA-loaded Dendritic Cells for Metastasised Uveal Melanoma

Melanoma, Uveal Metastatic

Germany
Philogen S.p.A.

Recruiting

Safety and Early Signs of Efficacy of IL12-L19L19. (DODEKA)

Advanced Solid Tumor | Metastatic Solid Tumor

Italy, Germany, Switzerland
Nicole Hildebrand
RWTH Aachen University

Recruiting

FGF19 in Obstructive Cholestasis: "Unveil the Signal" (FOCUS)

Pancreatic Neoplasms | Cholangiocarcinoma | Cholestasis | Liver Metastasis Colon Cancer | Icterus

Germany
University of Ulm
Sanofi; Assign Data Management and Biostatistics GmbH; Hubertus-Wald-Cancer Center...

Unknown

PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer (PERMAD)

Metastatic Colorectal Cancer

Germany
Universitätsmedizin Mannheim

Completed

Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream

Metastatic Colorectal Cancer

Slovenia, Germany
Heidelberg University
Dafra Pharma; Hector-Stiftung; Monika-Kutzner Stiftung, Berlin, Germany; HEIFAN-Heidelberger...

Completed

Study of Artesunate in Metastatic Breast Cancer (ARTIC-M33/2)

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Germany
Dr. Carl Schimanski

Unknown

FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema (DERMATUX)

Colorectal Cancer Metastatic

Germany
University Hospital Tuebingen

Terminated

Evaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb Study

Metastatic Melanoma (Carrying BRAF V600 Mutation)

Germany
iOMEDICO AG

Active, not recruiting

Registry Platform Colorectal Cancer (AZURITE)

Colorectal Cancer Metastatic

Germany
AIO-Studien-gGmbH
Amgen; ClinAssess GmbH

Completed

Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer (PanaMa)

Metastatic Colorectal Cancer

Germany
Heidelberg University
Verein für Krebsforschung, Arlesheim, Swizzerland; Weleda AG, D-73525 Schwäbisch...

Completed

Mistletoe Extract in Early or Advanced Breast Cancer, A Feasibility Study

Metastatic Breast Cancer

Germany
AIO-Studien-gGmbH
AstraZeneca

Completed

Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma (MEDISARC)

Recurrent Adult Soft Tissue Sarcoma | Metastatic Adult Soft Tissue Sarcoma

Germany
Hoffmann-La Roche

Terminated

A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain

Pain | Neoplasm Metastasis | Bone Neoplasm

United States, Italy, Chile, Russian Federation, Hungary, United Kingdom, Poland, Guatemala, Germany, Mexico, Puerto Rico, Greece, Australia, Switzerland, Argentina, Panama
German Cancer Research Center
University Hospital Heidelberg

Recruiting

A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients With Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma (IntenSify)

Pancreatic Cancer | Pancreatic Adenocarcinoma | CYP3A Inhibitor | Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic Neoplasm

Germany
German Cancer Research Center
University Hospital Heidelberg

Recruiting

CATCH: Implementation of Genomics-guided Precision Medicine in Metastatic Breast Cancer (CATCH)

Metastatic Breast Cancer

Germany
AIO-Studien-gGmbH
Celgene Corporation; ClinAssess GmbH

Completed

First-line Treatment of Metastatic Pancreatic Cancer With Nab-paclitaxel and Gemcitabine (ALPACA)

Adenocarcinoma of the Pancreas | Metastatic Pancreatic Cancer

Germany
Philogen S.p.A.

Active, not recruiting

A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

Metastatic Melanoma Stage IV

Italy, Germany
University Hospital, Essen

Recruiting

Enhancing Radioiodine Incorporation Into Radio Iodine Refractory Thyroid Cancers With MAPK Inhibition (ERRITI)

Metastatic Thyroid Cancer

Germany
AIO-Studien-gGmbH
Taiho Pharmaceutical Co., Ltd.; Nordic Pharma SAS

Completed

Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer (MATEO)

Esophageal Neoplasms | Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Gastric Neoplasm | Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Trium Analysis Online GmbH; mca Berlin

Completed

Observational Study on Quality of Life of Patients Receiving Nab-paclitaxel/Gemcitabine First Line Therapy, Including a Translational Program (QoliXane)

Metastatic Pancreatic Cancer

Germany
iOMEDICO AG
Amgen

Completed

Validation of a New Prognostic Score for Adult Patients With RAS Wild-type mCRC Treated With Vectibix® and FOLFIRI or FOLFOX in First Line (VALIDATE) (VALIDATE)

Metastatic Colorectal Cancer | RAS Wild-type

Germany
Martin Schuler, Prof. Dr. med.

Completed

Bi-weekly Cetuximab Combined With 5-fluorouracil/Leucovorin/Oxaliplatin (FOLFOX-6) in Metastatic Colorectal Cancer (CEBIFOX)

Metastatic Colorectal Cancer

Germany
Technische Universität Dresden

Completed

Safety of Cetuximab and Oxaliplatin/5-FU/FA/Irinotecan in First-Line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Germany
Ludwig-Maximilians - University of Munich
Roche Pharma AG

Unknown

Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic Cancer (ML22774)

Metastatic Pancreatic Adenocarcinoma

Germany
Terumo Europe N.V.
Universitaire Ziekenhuizen KU Leuven; Federation Francophone de Cancerologie...

Completed

LifePearl-Iri Pharmacokinetic Study

Metastatic Colorectal Cancer | mCRC

Belgium, Germany
HistoSonics, Inc.

Active, not recruiting

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK) (#HOPE4LIVER)

Liver Neoplasms | Hepatocellular Carcinoma | Liver Metastases

United Kingdom, Spain, Germany, Italy
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Ramucirumab Plus TAS-102 in Patients With Advanced or Metastatic Gastric Adenocarcinoma or the Gastroesophageal Junction (RE-ExPEL)

Gastric Adenocarcinoma | Metastatic Adenocarcinoma of the Gastroesophageal Junction

Germany
University Hospital Schleswig-Holstein

Recruiting

RAdiotherapy for Metastatic Spinal Cord Compression With Increased Radiation dosES (RAMSES-01)

Spinal Cord Compression Due to Metastasis to Spine

Germany
University Hospital Schleswig-Holstein

Completed

High-precision Radiotherapy of Motor Deficits Due to Metastatic Spinal Cord Compression (PRE-MODE)

Spinal Cord Compression Due to Metastasis to Spine

Germany
AVEO Pharmaceuticals, Inc.

Completed

A Phase 1b/2a, Open-Label, Multi-Center Study of Tivozanib (AV-951) in Combination With Paclitaxel in Subjects With Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Germany
Onxeo
Spectrum Pharmaceuticals, Inc

Completed

Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary

Carcinoma of Unknown Primary

United States, Germany, France, Denmark
Universität des Saarlandes

Recruiting

Prospective REgistry of Targeted RadionucLide TherapY in Patients With mCRPC (REALITY Study)

Prostate Cancer Metastatic | Advanced Prostate Carcinoma | Castration Resistant Prostatic Cancer

Germany
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Terminated

Study of Pembrolizumab Maintenance Following First-Line Platinum Based Chemotherapy in Patients With Metastatic Squamous - Non-Small Cell Lung Cancer (sNSCLC) (PRIMUS)

Metastatic Squamous Non-small Cell Lung Cancer

Germany
Genentech, Inc.
Hoffmann-La Roche

Recruiting

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

Neoplasm Metastasis

Australia, Korea, Republic of, China, United States, Portugal, Brazil, Singapore, Spain, United Kingdom, Belgium, Austria, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, France, Germany, Hong Kong, Hungary, Israel, Italy, Japan, Me... and more
Hoffmann-La Roche

Terminated

A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease

Pain | Neoplasm Metastasis | Bone Neoplasm

United States, Mexico, Germany, Russian Federation, Italy, Hungary, Belgium, Chile, France, Argentina, Australia, Switzerland, Guatemala, Puerto Rico, Poland, Panama, United Kingdom, Canada
University of Erlangen-Nürnberg Medical School

Completed

Analysis of CMV Infections in Patients With Brain Tumors or Brain Metastases During and After Radio(Chemo)Therapy (GLIO-CMV-01)

Cytomegalovirus Infections

Germany
iOMEDICO AG
Novartis Pharmaceuticals

Completed

First Line Pazopanib in Poor Risk Patients With Metastatic Renal Cell Carcinoma (FLIPPER)

Carcinoma, Renal Cell | Clear-cell Metastatic Renal Cell Carcinoma | Locally Advanced and/or Metastatic Renal Cell Carcinoma

Germany
Charite University, Berlin, Germany
Klinikum rechts der Isar, TU München, (TUM), Munich, Germany.

Recruiting

Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells (HSP70CTC)

Sarcoma | Prostate Cancer | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | Squamous Cell Carcinoma | Melanoma Stage IV

Germany
AIO-Studien-gGmbH
Bristol-Myers Squibb; Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Gilead... and other collaborators

Recruiting

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients (CRISP)

Small-cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Stage I | Metastatic Non-small Cell Lung Cancer (NSCLC) | Non Small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer Stage II

Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating Mitoxantrone in Multiple Sclerosis

Secondary Progressive Multiple Sclerosis

Germany
Vejle Hospital

Completed

Predictive Value of Drug Sensitivity Testing Tumorspheres From Patients With Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

Denmark, Germany

Clinical Trials on Neoplasm Metastasis in Germany

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