Clinical Trials on Neoplasms, Malignant in South Africa

Total 6546 results

Western Sydney Local Health District

Recruiting

ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study (COVERT)

Colorectal Neoplasm | Endoscopic Mucosal Resection

Australia
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); North Central Cancer Treatment Group

Completed

Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesothelioma

Mesothelioma

United States
Center for International Blood and Marrow Transplant...
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704) (BMT CTN 1704)

Hematologic Malignancy

United States
Monash University

Recruiting

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (RATIONALISE)

Hypogammaglobulinemia | Haematological Malignancy

Australia
International Atomic Energy Agency
Catholic University of the Sacred Heart; University of Cape Town; Tata Memorial... and other collaborators

Unknown

Resource-Sparing Curative Treatment for Rectal Cancer

Rectal Carcinoma

Algeria, Brazil, Canada, Colombia, Croatia, Cuba, India, Indonesia, Italy, Slovakia, South Africa
International Atomic Energy Agency

Completed

Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy

Non Small Cell Lung Cancer

Chile, China, Croatia, Egypt, India, Malaysia, Malta, Morocco, Pakistan, Panama, Peru, South Africa, Tunisia
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Montefiore... and other collaborators

Completed

Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

Skin Kaposi Sarcoma | Recurrent Kaposi Sarcoma

United States, Uganda, South Africa
St George Hospital, Australia

Completed

Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases

Neoplasm Metastasis | Brain Neoplasms

Australia
Eli Lilly and Company

Terminated

Enzastaurin in Combination of Capecitabine to Treat Breast Cancer

Breast Cancer

Mexico, France, Australia, Argentina, South Africa
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

Childhood Teratoma | Stage II Malignant Testicular Germ Cell Tumor | Stage III Malignant Testicular Germ Cell Tumor | Childhood Embryonal Tumor | Childhood Extracranial Germ Cell Tumor | Childhood Extragonadal Germ Cell Tumor | Childhood Malignant Ovarian Germ Cell Tumor | Childhood Malignant Testicular... and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
University of Sydney
National Health and Medical Research Council, Australia; Northern Sydney and...

Not yet recruiting

Ventilation Using Radiographic Examination: Functional Lung Imaging Techniques for the Reduction of Toxicity in Functional Avoidance Radiation Therapy (VENTURE)

Lung Neoplasm

Australia
Celgene
ICON Clinical Research

Completed

Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma.

Melanoma | Neoplasm Metastasis

Australia, United Kingdom, Ukraine, Germany, Estonia, Latvia, Lithuania, Netherlands, South Africa
AstraZeneca

Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (eVOLVE-Meso)

Unresectable Pleural Mesothelioma

Denmark, Italy, Australia, Korea, Republic of, Belgium, United States, Canada, Japan, United Kingdom, China, Brazil, France, Taiwan, Spain, Norway, Switzerland, Turkey, Poland, Germany, South Africa, Netherlands
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection

Cervical Cancer | Cervical Intraepithelial Neoplasia | CIN | Human Papilloma Virus | Cervical Dysplasia | HSIL of Cervix | Cervical Neoplasm | HSIL | High-Grade Squamous Intraepithelial Lesions | High-grade Cervical Intraepithelial Neoplasia

United States, Australia
Medical Research Council

Completed

Epirubicin and Cyclophosphamide Compared With Epirubicin and Paclitaxel in Treating Women With Metastatic Breast Cancer

Breast Cancer

United Kingdom, South Africa
Coherus Biosciences, Inc.
Community Clinical Oncology Research Network, LLC

Unknown

An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca (POEM)

Febrile Neutropenia | Non-myeloid Malignancy

United States
Prisma Health-Upstate
Clemson University

Completed

The Use of Virtual Reality During Breast Ultrasound-Guided Biopsy Procedures (VRBB)

Breast Neoplasm Female

United States
Prisma Health-Upstate
Clemson University

Completed

VR Ultrasound Guided Breast Localization

Breast Neoplasm Female

United States
Neovii Biotech
Fresenius Biotech North America

Completed

Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites

Malignant Ascites

United States
Ferring Pharmaceuticals

Completed

An Extension Study Evaluating the Long-Term Safety and Tolerability of Degarelix One-Month Depots in Prostate Cancer

Prostate Cancer

Belgium, Germany, Hungary, Netherlands, Romania, Russian Federation, South Africa
Aminex Therapeutics, Inc.

Recruiting

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Melanoma | Cervical Cancer | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Solid Tumor | Endometrial Cancer | Advanced Cancer | Diffuse Midline Glioma, H3 K27M-Mutant | Papillary Thyroid Cancer | Solid Carcinoma | Mesotheliomas Pleural | Glioma, Malignant | Ovary Cancer and other conditions

United States, Australia
Western Sydney Local Health District

Recruiting

The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study (ANZ UGI)

Gastric Cancer | Esophageal Neoplasms | Neuroendocrine Tumors | Gastric Adenocarcinoma | Cancer of Stomach | Oesophageal Cancer | Gastric Neoplasm | GIST | GI Cancer

Australia
Leiden University Medical Center
HollandPTC; Varian Medical Systems

Recruiting

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas (CHIPT)

Magnetic Resonance Imaging | Chondrosarcoma | Chordoma | Proton Therapy | Bone Neoplasm of Vertebral Column | PET-CT

Netherlands
University of Sydney
Austin Health; Peter MacCallum Cancer Centre, Australia; Western Sydney Local... and other collaborators

Recruiting

Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy (ROCK-RT)

Liver Neoplasm

Australia
Mural Oncology, Inc

Recruiting

Nemvaleukin Alfa (ALKS 4230) Monotherapy in Patients With Advanced Cutaneous Melanoma or Advanced Mucosal Melanoma - ARTISTRY-6 (ARTISTRY-6)

Cutaneous Melanoma | Mucosal Melanoma

United States, Australia, Canada, Italy, Korea, Republic of, Spain, Taiwan, United Kingdom
Novartis Pharmaceuticals

Completed

Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor (RADIANT-2)

Carcinoid Tumor | Malignant Carcinoid Syndrome

France, Spain, Netherlands, United States, Canada, Sweden, Italy, Australia, Germany, Greece, Belgium, Czech Republic, Slovakia, Finland, United Kingdom
National Cancer Institute (NCI)

Terminated

Costa Rican Natural History Study of HPV and Cervical Neoplasia

Cervical Neoplasia

Costa Rica
Sanofi

Completed

A Clinical Trial of Patients With Solid Tumours Receiving Granulocyte Colony Stimulating Factor as Primary Prophylaxis for Chemotherapy-induced Neutropenia, in a Docetaxel Based Regimen (Grano-Tax)

Neoplasms (no Otherwise Specified)

South Africa
Radiation Therapy Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

Chemotherapy Plus Radiation Therapy With or Without Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

Lung Cancer

United States, South Africa
Medical University of South Carolina

Terminated

Cisplatin and Pemetrexed With Radiation Followed by Lobectomy (CisPemXetSrg)

Nonsquamous Nonsmall Cell Neoplasm of Lung | Nonsmall Cell Lung Cancer Stage III

United States
Melanoma Institute Australia
Bristol-Myers Squibb; Melanoma and Skin Cancer Trials Limited

Active, not recruiting

Anti-PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases (ABC)

Melanoma | Brain Metastases

Australia
Novartis Pharmaceuticals

Terminated

Myelodysplastic Syndrome (MDS) Gastrointestinal (GI) Tolerability Study (MACS1574)

Myelodysplastic Syndrome | Transfusional Iron Overload

Spain, France, Italy, South Africa
International Atomic Energy Agency

Completed

CRP on Radiobiological and Clinical Studies on Viral-Induced Cancer's Response to Radiotherapy

Cervix Cancer

Peru, Korea, Republic of, Morocco, Austria, Brazil, Canada, India, Macedonia, The Former Yugoslav Republic of, Pakistan, South Africa, United Kingdom
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Early Chemotherapy Based on CA 125 Level Alone Compared With Delayed Chemotherapy in Treating Patients With Recurrent Ovarian Epithelial , Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

Spain, Belgium, France, Netherlands, Austria, United Kingdom, Italy, South Africa, Portugal, Ireland
Eli Lilly and Company

Completed

Pemetrexed-Carboplatin and Gemcitabine-Vinorelbine in Advanced Breast Cancer

Breast Cancer

Italy, Spain, Turkey, Germany, South Africa
Medical Research Council

Unknown

Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease

Lymphoma

United Kingdom, South Africa
Melanoma Institute Australia

Withdrawn

Intralesional Sclerosant for in Transit and Cutaneous Melanoma Metastases (INTRANS)

Melanoma | In-Transit Metastasis of Cutaneous Melanoma

Australia
Universitaire Ziekenhuizen KU Leuven
University of Sydney

Completed

Presentation of First Time Attenders at Lymphedema Clinics

Lymphedema | Breast Neoplasm

Belgium, Australia
National Cancer Institute (NCI)

Completed

Alisertib in Treating Patients With Advanced or Metastatic Sarcoma

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Recurrent Adult Soft Tissue Sarcoma | Myxofibrosarcoma | Recurrent Leiomyosarcoma | Recurrent Malignant Peripheral Nerve Sheath Tumor | Recurrent Undifferentiated Pleomorphic Sarcoma | Recurrent Liposarcoma

United States
University Health Network, Toronto
Canadian Cancer Trials Group; Young Investigator Award - American Society of... and other collaborators

Completed

Cognitive Function and Fatigue in Colorectal Cancer (CRC) Patients After Chemotherapy

Fatigue | Colorectal Neoplasm | Cognition

Canada, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors

Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Canada, United States, Australia, Puerto Rico
Hellenic GenitoUrinary Cancer Group

Recruiting

Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy

Bladder Cancer

Greece
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment (PI-GTN)

Gestational Trophoblastic Neoplasia

United Kingdom
European Organisation for Research and Treatment...

Completed

Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer

Colorectal Cancer

France, Belgium, Germany, Austria, Egypt, Netherlands, South Africa, Italy, Russian Federation
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Malignant Solid Neoplasm | COVID-19 Infection | Hematopoietic and Lymphatic System Neoplasm

United States
Hoffmann-La Roche

Completed

A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases

Malignant Melanoma

Spain, United States, Canada, Germany, Netherlands, France, Italy, United Kingdom, Israel, Australia
Hellenic GenitoUrinary Cancer Group

Active, not recruiting

Efficacy of Durvalumab in Non-muscle-invasive Bladder Cancer

Bladder Cancer

Greece
University of West Attica

Unknown

Implementing Enhanced Recovery After Surgery (ERAS) Pathways In Major Gynecologic Oncology Operations In Greece (ERAS)

Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer | Hysterectomy

Greece
ETOP IBCSG Partners Foundation

Completed

Low-dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-negative Early Breast Cancer (22-00)

Breast Cancer

Italy, Switzerland, Australia, Peru, South Africa, Chile, Belgium, Brazil, Romania, Hungary, Nigeria
Elios Therapeutics, LLC
LumaBridge

Recruiting

Autologous TLPO Vaccine Basket

Cancer | Tumor | Tumor, Solid | Tumor Metastasis

United States

Clinical Trials on Neoplasms, Malignant in South Africa

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