Clinical Trials on Neoplasms, Rectal

Total 176154 results

Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
Norwegian University of Science and Technology
St. Olavs Hospital

Terminated

Exercise Training for Rectal Cancer Patients

Rectal Neoplasms

Norway
Asan Medical Center
Hoffmann-La Roche

Completed

Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab (CLIMB)

Neoplasm Metastasis | Colorectal Neoplasms | Rectal Neoplasms | Colonic Neoplasms

Korea, Republic of
National Cancer Institute (NCI)

Terminated

Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal...

United States
Leiden University Medical Center
Medical Center Haaglanden; Surgimab

Not yet recruiting

SGM-101 in Colorectal Brain Metastases. (SGM-CBM)

Brain Diseases | Gastrointestinal Neoplasms | Colorectal Neoplasms | Intestinal Neoplasms | Brain Neoplasms | Rectal Neoplasms | Brain Cancer | Brain Tumor | Gastrointestinal Cancer | Brain Metastases | Gastrointestinal Disease | Intestinal Disease | Rectum Cancer

Netherlands
Cliniques universitaires Saint-Luc- Université...

Completed

Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy

Head and Neck Cancer | Prostate Cancer | Rectum Cancer

Belgium
University of Southern California
National Cancer Institute (NCI)

Withdrawn

Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal...

United States
National Institutes of Health Clinical Center (CC)

Completed

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Seoul National University Hospital
National Cancer Center, Korea; Seoul National University Bundang Hospital; SMG-SNU...

Recruiting

The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS) (TraLARS)

Sleep Disorder | Insomnia | Low Anterior Resection Syndrome | Rectal Cancer

Korea, Republic of
Ludwig-Maximilians - University of Munich

Recruiting

Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE) (LANACARE)

Quality of Life | Chemoradiation | Anal Cancer

Germany
Juergen Debus

Recruiting

Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy (DILANA)

Anal Cancer

Germany
Siemens Molecular Imaging

Completed

Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic Drug (K5-101)

Non-squamous Non-small Cell Lung Cancer | Metastatic Breast Cancer | Metastatic Colon/Rectum Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
National Cancer Institute (NCI)

Completed

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Maimonides Medical Center

Completed

Fluorescent Evaluation of Colorectal Anastamoses

Rectal Neoplasms | Diverticulitis | Colon Neoplasms

United States
J. Uriach and Company

Unknown

Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.

Colorectal Neoplasm | Iron Deficiency Anemia

Spain
Radboud University Medical Center

Completed

Incidence, Risk Factor, Treatment and Overall Survival of Locally Recurrent Rectal Cancer

Rectal Neoplasms | Neoplasm Recurrence, Local
Royal Marsden NHS Foundation Trust

Unknown

Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

Canada, United Kingdom, Brazil, Cyprus
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
East Lancashire Hospitals NHS Trust
Lancaster University

Completed

Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery (SPECS)

Liver Metastases | Cancer of Colon | Cancer of Rectum

United Kingdom
University of Turku
Helsinki University Central Hospital

Completed

Educational Nursing Intervention Among Patients With Colorectal Cancer During Chemotherapy

Self Care | Patient Empowerment | Cancer of Colon | Cancer of Rectum | Patient Activation

Finland
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

Canada
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
John Hays
Sanofi

Unknown

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
Instituto Nacional de Cancerologia, Columbia
Universidad Nacional de Colombia

Unknown

Efficacy and Safety of a Preoperative Aerobic Exercise Program in Patients With Gastrointestinal Cancer.

Stomach Neoplasms | Rectal Neoplasms | Colonic Neoplasms | Liver Neoplasm

Colombia
GlaxoSmithKline

Terminated

Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer

Carcinoma, Renal Cell

United States
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer

Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
Washington University School of Medicine

Active, not recruiting

Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps

Rectal Cancer | Colon Cancer | Cancer of the Colon | Cancer of the Rectum | Precancerous Polyp | Malignant Polyp

United States
John Hays
Amgen

Unknown

Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Swedish Medical Center
Novartis Pharmaceuticals

Completed

Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Roswell Park Cancer Institute
Merck Sharp & Dohme LLC

Completed

Vorinostat, Fluorouracil, and Leucovorin Calcium in Treating Patients With Metastatic Colorectal Cancer That Has Not Responded to Previous Treatment

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Moroccan Society of Surgery
Institut National d'Oncologie Sidi Mohammed Ben Abdellah

Completed

Pseudo Continent Perineal Colostomy vs Permanent Left Iliac Colostomy After Abdominoperineal Resection for Ultra Low Rectal Adenocarcinoma

Quality of Life | Rectal Neoplasms | Colostomy Stoma

Morocco
McGill University Health Centre/Research Institute...

Unknown

Pre-habilitation to Improve Outcomes in Patients Undergoing Liver Resection for Cancer

Colorectal Neoplasm | Liver Neoplasm | Biliary Tract Neoplasm

Canada
National Cancer Institute (NCI)

Completed

Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
Centre Antoine Lacassagne

Completed

Impact of a Telephonic Monitoring During Inter-treatment Intervals on Emotional State, Quality of Life and Toxicities, on Neo Adjuvant or Adjuvant Chemotherapy-treated Patients (EMOTION)

Non-metastatic Patients With Breast Cancer | Non-metastatic Patients With Colon Cancer | Non-metastatic Patients With Rectal Cancer | Patients Undergoing Adjuvant Chemotherapy

France
King Faisal Specialist Hospital & Research Center

Completed

First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study

Rectal Neoplasms | Colonic Neoplasms
University Hospital, Akershus
University of Oslo; Oslo University Hospital

Completed

Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness (OxyTarget)

Gastrointestinal Diseases | Gastrointestinal Neoplasms | Rectal Diseases | Rectal Neoplasms

Norway
AC Camargo Cancer Center

Unknown

Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers (BMACR)

Colon Cancer Stage IIb | Rectum Cancer, Adenocarcinoma | Colon Cancer Stage IIIa | Colon Cancer Stage IIIc | Colon Cancer Stage IIIb

Brazil
National Cancer Institute (NCI)
NSABP Foundation Inc

Completed

Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
Jagiellonian University

Active, not recruiting

dataBase for Analysis of Rectal Cancer Oncological Results (BARO)

Rectal Cancer | Lymph Node Metastases | Metformin | Overall Survival | Disease-free Survival

Poland
University of Oulu

Active, not recruiting

PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure

Rectum Cancer

Finland
Sorlandet Hospital HF
Oslo University Hospital; University Hospital of North Norway; Helse Stavanger... and other collaborators

Completed

Symptoms and Quality of Life (QoL) After Palliative Pelvic Radiation of Prostate and Rectal Cancers (PallRad1)

Prostatic Neoplasms | Rectal Neoplasms

Norway
Ohio State University Comprehensive Cancer Center
Novartis Pharmaceuticals; National Comprehensive Cancer Network

Completed

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
SafeHeal Inc

Terminated

SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study (SAFE-2)

Colorectal Cancer | Rectal Cancer | Rectal Tumor | Rectal/Anal

United States, France, Belgium
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer (AZUR-1)

Neoplasms, Rectal

United States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands

Clinical Trials on Neoplasms, Rectal

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