Clinical Trials on Neoplasms, Rectal

Total 177716 results

AUSL Romagna Rimini
AstraZeneca; Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori

Recruiting

Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer (PANDORA)

RECTAL CANCER

Italy
Radboud University Medical Center

Completed

Transanal Endoscopic Microsurgery (TEM) After Radiochemotherapy for Rectal Cancer (CARTS)

Rectal Tumour

Netherlands
Hospital Universitario Virgen de la Arrixaca

Completed

Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer

RECTAL CANCER
Institute of Oncology Ljubljana

Unknown

IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment (BISER)

Rectal Carcinoma

Slovenia
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore
University of Oulu

Active, not recruiting

PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure

Rectum Cancer

Finland
Fudan University
Shanghai Zhongshan Hospital; RenJi Hospital; First Hospital of China Medical... and other collaborators

Not yet recruiting

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Rectal Cancer | RECTAL NEOPLASMS
Sorlandet Hospital HF
Oslo University Hospital; University Hospital of North Norway; Helse Stavanger... and other collaborators

Completed

Symptoms and Quality of Life (QoL) After Palliative Pelvic Radiation of Prostate and Rectal Cancers (PallRad1)

Prostatic Neoplasms | Rectal Neoplasms

Norway
Ohio State University Comprehensive Cancer Center
Novartis Pharmaceuticals; National Comprehensive Cancer Network

Completed

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Azienda Policlinico Umberto I

Completed

Surgical Treatment of Pancreatic RCC Metastases

Renal Cell Carcinoma | Metastases, Neoplasm

Italy
Sixth Affiliated Hospital, Sun Yat-sen University

Unknown

Bevacizumab-containing Regimen for Metastatic Colorectal Cancer Failed to Cytotoxic Treatment (BATTLE)

Colorectal Cancer | Neoplasm | Metastatic Neoplasm

China
SafeHeal Inc

Terminated

SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study (SAFE-2)

Colorectal Cancer | Rectal Cancer | Rectal Tumor | Rectal/Anal

United States, France, Belgium
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer (AZUR-1)

Neoplasms, Rectal

United States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands
Zhen-Hai Lu

Recruiting

Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer

Advanced Rectal Cancer

China
Corporacion Parc Tauli

Recruiting

PREHABILITATION RECTAL CANCER DURING ADJUVANCY VS BEFORE SURGERY (prehab-cspt)

Colo-rectal Cancer

Spain
Vejle Hospital

Active, not recruiting

Single-stapled Double Purse-string Technique for Colorectal Anastomosis

Colo-rectal Cancer

Denmark
Gruppo Oncologico del Nord-Ovest

Completed

Immunotherapy In Locally Advanced Rectal Cancer (AVANA)

Colon Rectal Cancer

Italy
Check-Cap Ltd.

Completed

Safety,Usability and Compliance of Using C-Scan System for Providing Information on Colonic Polypoid Lesions and Masses (C-Scan)

Colo-rectal Cancer

United States
Sun Yat-sen University

Active, not recruiting

Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

Advanced Rectal Cancer

China
Vilnius University

Terminated

Early Versus Late Closure of Preventive Ileostomy

Ileostomy, Rectal Cancer

Lithuania
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Problem Solving Skills Training in Adult Cancer Survivors: Bright IDEAS-AC

Colo-rectal Cancer

United States
Check-Cap Ltd.

Completed

Development Study of Check-Cap Imaging System in Healthy Volunteers

Colo-rectal Cancer

Israel
Exact Sciences Corporation

Completed

Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.

Colo-rectal Cancer

United States
Richard Crosby
Centers for Disease Control and Prevention

Completed

Assessing Repeat Fit Testing for CRC (ARFT)

Colo-rectal Cancer

United States
Osama Mohammad Ali ElDamshety

Unknown

Outcomes of TAMIS-Total Mesorectal Excision Versus Transanal Loco-regional Excision for T2 Low Rectal Cancer (TAMIS)

Low Rectal Cancer
Shoichi Fujii, MD, PhD

Unknown

Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection

Rectal Cancer | Colon Rectal Resection

Japan
Kaunas University of Medicine

Unknown

Preoperative Chemoradiation Versus Short Term Radiation Alone With Delayed Surgery for Stage II and III Resectable Rectal Cancer

Primary Rectal Cancer

Lithuania
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Rectal Adenocarcinoma

United States
Fundació Institut Germans Trias i Pujol
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Hospital General Universitario Elche and other collaborators

Unknown

Endoscopic Full-Thickness Resection In Colon (EFTRICOM)

Colorectal Neoplasms | Colorectal Cancer | Colo-rectal Cancer | Colonic Cancer | Colorectal Adenocarcinoma | Colon Polyp | Colon Neoplasm, Malignant | Colonic Adenoma | Colon Lesion | Colon Neoplasm

Spain
Prof. Dr. Carl Schimanski

Completed

L-BLP25 in Patients With Colorectal Carcinoma After Curative Resection of Hepatic Metastases (LICC)

Colon Carcinoma | Rectum Carcinoma

Germany, Austria
Centre Francois Baclesse
Accuray Incorporated

Active, not recruiting

Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life (CANAL-IMRT-01)

Locally Advanced Anal Canal Cancer

France
Sun Yat-sen University

Active, not recruiting

Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.

Laparoscopic Surgery | Rectal Neoplasms | Neoplastic Cells, Circulating | Transanal Endoscopic Surgery

China
First Affiliated Hospital of Guangxi Medical University

Recruiting

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer

Rectal Cancer | Rectal Cancer Stage II | Rectal Cancer Stage III

China
Jules Bordet Institute

Recruiting

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer (REGINA)

Rectal Cancer Stage II | Rectal Cancer Stage III

Belgium, France
Branimir Sikic
AstraZeneca

Completed

Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer

Colorectal Neoplasms | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer

United States
Washington University School of Medicine

Recruiting

Ultrasound and Photoacoustic Imaging of Colon and Rectal Tumor Tissue

Rectal Cancer

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Is There a Link Between Anatomical Markers of Surgical Difficulty and Incapacity to Reverse Stoma After Low Rectal Cancer Surgery? (persist stomie)

Rectal Surgery

France
UNC Lineberger Comprehensive Cancer Center

Completed

PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study

Rectal Carcinoma

United States
University of California, San Francisco

Terminated

Evaluation of Rectal Cancer Treatment Response Using PET/MRI (Rectal PET/MRI)

Rectal Adenocarcinoma

United States
IHU Strasbourg

Terminated

Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology (TRaMA)

Rectal Cancer | Rectal Adenocarcinoma

France
Institut Bergonié
Groupement Interrégional de Recherche Clinique et d'Innovation

Completed

Immune Mechanisms After Radiofrequency Ablation of Pulmonary Metastases From Colorectal Cancer Origin (ARFIM)

Neoplastic Cells, Circulating | Colo-rectal Cancer | Circulating Tumor Cell | Pulmonary Metastasis | Immune Evasion, Tumor

France
Fujian Cancer Hospital

Not yet recruiting

A Phase II Multicenter Clinical Study of Improved Short-course Radiotherapy Combined With CAPOX and PD-1 Monoclonal Antibody for Locally Advanced Mid-low Rectal Cancer

Mid-low Rectal Cancer
Beijing Friendship Hospital
Changhai Hospital; The First Affiliated Hospital of Anhui Medical University; Fudan University and other collaborators

Recruiting

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer: From a Multicenter Phase II Cohort to a Phase III Randomized Controlled Study

Locally Advanced Rectal Carcinoma

China
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
University of Hull
Hull University Teaching Hospitals NHS Trust

Not yet recruiting

Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Sun Yat-sen University
Akeso; Haplox Biotechnology Co., Ltd.

Recruiting

Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Peking Union Medical College Hospital

Not yet recruiting

TIME in Immunotherapy Combined With nCRT for Rectal Cancer (TIMENT-R)

Locally Advanced Rectal Cancer
Beijing Friendship Hospital
Peking University First Hospital; Peking University People's Hospital; Peking... and other collaborators

Recruiting

Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer (POLAR-STAR)

Locally Advanced Rectal Cancer

China
Zhejiang Cancer Hospital

Recruiting

Dendrobium Huoshanense Suppository in Rectal Cancer

Locally Advanced Rectal Cancer

China
Istanbul Training and Research Hospital

Recruiting

The Role of Vitamin D in Predicting Response to Neoadjuvant Therapy in Patients With Rectal Cancer

Rectal Cancer | Stage III Rectal Cancer

Turkey

Clinical Trials on Neoplasms, Rectal

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