Clinical Trials on Neoplasms

Total 107429 results

National Cancer Institute (NCI)

Completed

Vorinostat, Azacitidine, and Gemtuzumab Ozogamicin for Older Patients With Relapsed or Refractory AML

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
Paolo Caimi, MD
National Cancer Institute (NCI)

Completed

Lithium Carbonate and Tretinoin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma | Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Recurrent Adult T-cell Leukemia/Lymphoma | Recurrent Cutaneous T-cell...

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction Chemotherapy

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities and other conditions

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
National Cancer Institute (NCI)

Completed

PS-341 in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia in Blast Phase, or Myelodysplastic Syndrome

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Promyelocytic Leukemia (M3) | Previously Treated Myelodysplastic Syndromes | Recurrent Adult Acute Lymphoblastic Leukemia | Relapsing Chronic Myelogenous Leukemia | Refractory Anemia With Excess Blasts | Blastic Phase Chronic Myelogenous Leukemia and other conditions

United States
National Cancer Institute (NCI)

Completed

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Recurrent Classic Hodgkin Lymphoma | Refractory... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia in Remission | Refractory Anemia With Excess Blasts | Refractory... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphoma

Mycosis Fungoides | Recurrent Angioimmunoblastic T-Cell Lymphoma | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Anaplastic Large Cell Lymphoma | Recurrent Anaplastic Large Cell Lymphoma | Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified | Recurrent Enteropathy-Associated... and other conditions

United States
National Cancer Institute (NCI)

Completed

Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States, Israel
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Small Lymphocytic... and other conditions

United States
Ohio State University

Not yet recruiting

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Movement Disorders | Aging | Behavior | Dementia With Lewy Bodies | Emergency Psychiatric | Cognition Disorder | Antipsychotics and Neuroleptics Toxicity | Alteration in Mental Status
King's College Hospital NHS Trust

Not yet recruiting

Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE) (SELF-BREATHE)

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Lung Cancer | Interstitial Lung Disease | Chronic Lung Disease | Dyspnea | Fibrotic Lung Disease

United Kingdom
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Hospital Affiliated to the Institute of Neurology...

Not yet recruiting

Clinical Value of DWI-ADC Matching in the Short-term Prognosis of Wilson's Disease

Hepatolenticular Degeneration; Wilson

China
University of California, San Francisco

Not yet recruiting

Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy (ReINFORCE)

Demyelinating Diseases | Clinically Isolated Syndrome, CNS Demyelinating | Multiple Sclerosis Brain Lesion | Multiple Sclerosis Acute and Progressive | Demyelination; Corpus Callosum

United States
1ST Biotherapeutics, Inc.

Not yet recruiting

A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418

Amyotrophic Lateral Sclerosis (ALS) | Parkinson Disease Psychosis
Mexbrain
Integrated Scientific Services (ISS) AG

Recruiting

Performance and Safety of MEX-CD1 Low-volume Continuous Veno-venous Haemodialysis Medical Device for Copper-extraction in Patients With Wilson's Disease (MEXWILS)

Hepatolenticular Degeneration; Wilson

France, Spain
Monash University
Novartis Pharmaceuticals

Recruiting

VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN) (v-ASCERTAIN)

Cerebrovascular Disease | Coronary Heart Disease (CHD) | Peripheral Arterial Disease (PAD) | Atherosclerotic Cardiovascular Disease (ASCVD)

Australia
Jean Dubuisson

Not yet recruiting

Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach

Quality of Life | Adnexal Diseases | Sexual Dysfunction | Pelvic Pain | Complication | Sexuality | Dyspareunia | Gynecologic Disease | Adnexal Mass | Pathology | Adnexal Cyst
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Vanderbilt University Medical Center

Recruiting

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Hypertension | Multiple System Atrophy | Pure Autonomic Failure | Autonomic Failure

United States
University of Colorado, Denver

Completed

Post-Prandial Liver Glucose Metabolism in PCOS (PLUM)

Obesity | Polycystic Ovarian Syndrome | Hepatic Steatosis

United States
Jagiellonian University

Completed

Subclinical Hypothyroidism and Normogonadotropic Anovulation

Polycystic Ovary Syndrome | Hypothalamic-Pituitary-Ovarian Axis Dysfunction (Disorder)

Poland
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
AdventHealth
Integra LifeSciences Corporation

Withdrawn

BioDFence® G3 For Full Nerve-Sparing Robotic-Assisted Radical Prostatectomy

Prostate Cancer | Prostatectomy | Incontinence, Urinary | Erectile Dysfunction Following Radical Prostatectomy

United States
University of Oxford
Mayo Clinic; University of California, San Francisco; Surrey Sleep Research Centre...

Completed

Manipulating and Optimising Brain Rhythms for Enhancement of Sleep (MORPHEUS)

Epilepsy | Chronic Pain | Parkinson Disease | MSA - Multiple System Atrophy

United Kingdom
Swedish Orphan Biovitrum

Completed

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Arthritis, Juvenile | Lymphohistiocytosis, Hemophagocytic | Macrophage Activation Syndrome | Adult Onset Still Disease

United States, Spain, United Kingdom, France, Italy
University Hospital, Strasbourg, France

Terminated

Tele-expertise in Patients With Diabetes Hospitalized for Covid-19 Infection (COVIDEX)

Diabetic Patient (Type 1,2, MODY, Secondary) or With Corticosteroid-induced Diabetes Following Initiation of Corticosteroid Treatment

France
Vanderbilt University

Completed

Local Heat Stress in Autonomic Failure Patients With Supine Hypertension

Hypertension | Multiple System Atrophy | Pure Autonomic Failure | Autonomic Failure

United States
University Hospital, Toulouse

Completed

Evaluation of the Containment Impact Linked to the Covid-19 Pandemic in a Population of Parkinson Patients (ERCO-Park)

Parkinson Disease | COVID

France
University Hospital, Brest

Completed

Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD (GeneQuest)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

France
Vanderbilt University Medical Center

Terminated

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

Shy-Drager Syndrome | Pure Autonomic Failure | Orthostatic Hypotension, Dysautonomic | Autonomic Nervous System Disorders

United States
Excelsior

Completed

A Retrospective Study to Assess the Clinical Efficacy and Safety of Trientine in Wilson's Disease Patients

Trientine Treatment for Wilson's Disease

Taiwan
Hospital de Clinicas de Porto Alegre

Unknown

Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome

Obesity | Polycystic Ovary Syndrome | Hyperandrogenism

Brazil
Rainer Oberbauer
Amgen

Completed

Effect of Etelcalcetide on Cardiac Hypertrophy in Hemodialysis Patients (EtECAR-HD)

Secondary Hyperparathyroidism | Left Ventricular Hypertrophy | Chronic Kidney Disease Requiring Chronic Dialysis

Austria
University of Calgary
International Collaboration on Repair Discoveries

Unknown

Spinal Cord Stimulation and Autonomic Response in People With SCI.

Spinal Cord Injuries | Autonomic Dysreflexia | Orthostatic Hypotension, Dysautonomic

Canada
University of Virginia

Withdrawn

Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess

Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia

United States
Vanderbilt University

Completed

The Autonomic Nervous System and Obesity

OBESITY | HYPERTENSION | PURE AUTONOMIC FAILURE | SHY-DRAGER SYNDROME

United States
Mayo Clinic
Polycystic Kidney Disease Foundation

Completed

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study

Kidney, Polycystic, Autosomal Dominant

United States
Pontificia Universidad Catolica de Chile

Completed

Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud

Lupus Erythematosus, Systemic | Dermatomyositis | Ultrasound Therapy; Complications | Raynaud Disease | Raynaud Phenomenon Due to Trauma | System; Sclerosis

Chile
Maastricht University Medical Center

Unknown

Food Reward in Cachexia Induced by Acute or Chronic Disease

Chronic Obstructive Pulmonary Disease | Pancreatic Cancer | Cachexia | Non-small Cell Lung Cancer

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Polycystic Ovary Syndrome | Atherosclerosis | Carotid Artery Diseases
Catholic University of the Sacred Heart

Completed

Combined Therapy With Myo-inositol and Alpha-Lipoic Acid in PCOS Women

Polycystic Ovary Syndrome | Hyperandrogenism | Menstrual Pattern | Metabolic Features
Georgetown University
Solstice Neurosciences

Completed

Myobloc Atrophy Study (MAS)

Stroke | Brain Injury | Tumor | Spinal Cord Injury (SCI) | Spasticity Secondary to Either a Disorder or Trauma

United States
Tel Aviv University

Unknown

Meal Timing on Glucose Metabolism and Hyperandrogenism in Lean Women With Polycystic Ovary Syndrome (M-PCOS)

Hyperandrogenism | Insulin Resistance

Israel
Stony Brook University
National Institute of Mental Health (NIMH)

Completed

Methylphenidate for Treating Children With ADHD and Tourette Syndrome

Tourette Syndrome | Attention Deficit Disorder With Hyperactivity

Clinical Trials on Neoplasms

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