Clinical Trials on Neurodegeneration

Total 9896 results

Istituto Nazionale di Ricovero e Cura per Anziani

Completed

Effect of Remote Cognitive Intervention in Patients With Parkinson's Disease During the COVID-19 Pandemic (TELEPARK)

COVID-19 | Parkinson Disease | Mild Cognitive Impairment

Italy
Auburn University

Completed

Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD) ((AU-ROOAD))

Alzheimer Disease | Cerebral Amyloid Angiopathy

United States
Ospedale Generale Di Zona Moriggia-Pelascini
Ospedale di Vipiteno-Sterzing (SABES-ASDAA)

Completed

Application of Machine Learning Method in Validation of Screening Cognitive Test for Parkinsonisms (CoMDA-ML-P)

Supranuclear Palsy, Progressive | Multiple System Atrophy | Primary Parkinsonism | Secondary Vascular Parkinson Disease

Italy
University of Coimbra

Completed

From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1 (ASD/NF1inhib)

Autism Spectrum Disorder | Neurofibromatosis 1

Portugal
Shire

Terminated

Natural History Study of Children With Metachromatic Leukodystrophy

Metabolic Diseases | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Demyelinating Diseases | Genetic Diseases, Inborn | Metabolism, Inborn Errors | Lysosomal Storage Diseases | Lipid Metabolism Disorders | Sphingolipidoses | Hereditary Central Nervous System Demyelinating Diseases and other conditions

United States, Denmark, France, Argentina, Belgium, Brazil, Canada, Germany, Japan, Turkey
University of Bergen
NKS Olaviken Alderspsykiatriske sykehus

Completed

Tailored Music Therapy for Dementia

Dementia, Vascular | Alzheimer Dementia | Dementia, Lewy Body | Dementia Parkinson's Disease

Norway
Institut National de la Santé Et de la Recherche...

Unknown

Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System (ECOCAPTURE)

Parkinson Disease | Depressive Symptoms | Frontotemporal Dementia | Apathy

France
Federal University of São Paulo

Completed

Diagnosis of Carpal Tunnel Syndrome: Effectiveness of Diagnostic Tests. Clinical Trial of Accuracy (DCTS)

Carpal Tunnel Syndrome | Compression Neuropathy, Carpal Tunnel | Median Neuropathy, Carpal Tunnel

Brazil
Fundacion Clinic per a la Recerca Biomédica

Completed

2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism ([F18]-FDDNP)

Parkinsonism | Progressive Supranuclear Palsy | Multi-System Atrophy

Spain
Pontifical Catholic University of Argentina

Completed

Clinical Registry of Patients Under Treatment With Atypical Antipsychotics

Schizophrenia | Major Depressive Disorder | Bipolar Depressive Disorder | Parkinson's Disease With Hallucinations
Clionsky Neuro Systems Inc.

Completed

COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE

Brain Injuries | Hypoxia | Parkinson's Disease | Anemia | TDP-43 Proteinopathies | Dementia | Tauopathies | Mild Cognitive Impairment | Iron Deficiency | Vitamin B 12 Deficiency | Frontotemporal Dementia | Vascular Dementia | Alzheimer's Disease | Neurodegenerative Disorders | TBI | Lewy Body Dementia | Hyperhomocysteinemia
Queen Mary University of London

Not yet recruiting

The Use of the CUE1 in People With Parkinson's Disease and Related Disorders

Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Tremor | Parkinson's Disease and Parkinsonism | Vascular Parkinsonism
Chinese University of Hong Kong

Recruiting

Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE) (LANDSCAPE)

Parkinson Disease | Aging | Dementia Alzheimers | Depression in Old Age | Dementia Frontotemporal

Hong Kong
Medipol University

Recruiting

The Effect of Spinal Orthosis on the Development of Scoliosis and Chest Deformity in Type I Spinal Muscular Atrophy

Scoliosis | Exercise | Pulmonary Rehabilitation | Spinal Muscular Atrophy Type I | Chest Deformities | Spinal Orthosis

Turkey
Vico Therapeutics B. V.

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Huntington Disease | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1

Israel, Germany, United Kingdom, Poland, Denmark, Netherlands, France
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
Xuanwu Hospital, Beijing
H. Lundbeck A/S; Hoffmann-La Roche; Millennium Pharmaceuticals, Inc.; Biogen; XINGIMAGING... and other collaborators

Recruiting

Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases

Alzheimer Disease | Frontotemporal Dementia | Progressive Supranuclear Palsy

China
The Leeds Teaching Hospitals NHS Trust
University of Leeds

Not yet recruiting

Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal Amyloidosis

Dementia | Alzheimer Disease | Amyloid | Medullary Thyroid Cancer
Rutgers, The State University of New Jersey

Recruiting

Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders

Parkinson Disease | Movement Disorders | Huntington Disease | Essential Tremor | Spinocerebellar Ataxias | Dystonia, Primary

United States
University of Massachusetts, Amherst
University of Maryland, Baltimore; Yale University; National Institute on Aging... and other collaborators

Active, not recruiting

Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial

Dementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Dementia, Mild | Dementia Moderate | Dementia Frontal

United States
University of Washington
National Institute on Aging (NIA)

Completed

Innovations in Dementia Empowerment and Action (IDEA)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Vascular Dementia | Lewy Body Dementia | Parkinson Disease Dementia

United States
University of Milano Bicocca

Completed

Neurological Soft Signs in Neurodegenerative Dementias (DemeNSS)

Alzheimer Disease | Corticobasal Degeneration | Frontotemporal Dementia | Dementia With Lewy Bodies

Italy
University of Wisconsin, Madison
National Institute on Aging (NIA)

Completed

A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research

Cognitive Dysfunction | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia

United States
St. Justine's Hospital
CHU de Quebec-Universite Laval; Montreal Children's Hospital of the MUHC

Active, not recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Low-grade Glioma | Plexiform Neurofibroma | Central Nervous System Glioma

Canada
University of North Carolina, Greensboro

Completed

Rhythmically Entrained Exercise in Community-Dwelling Older Adults (REECO)

Depression | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Exercise | Caregiver Burden | Healthy Aging | Fall | Mild Cognitive Impairment | Elderly | Executive Function | Gait | Mental Health | Cognitive Decline | Memory Disorders | Memory Impairment | Walking | Cognition | Physical Exertion | Music Therapy and other conditions

United States
Assistance Publique - Hôpitaux de Paris

Completed

Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor (Es-Alert)

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy

France
University of Oxford
Medical Research Council

Completed

Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy (STAG-MSA)

Multiple System Atrophy | Gait Disorders, Neurologic | Bladder, Neurogenic | Autonomic Failure | Postural Hypotension

United Kingdom
University of Texas Southwestern Medical Center

Completed

Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin

Cervical Dystonia | Spasticity, Muscle | Hemifacial Spasm | Blepharospasm | Limb Dystonia | Fragments of Torsion Dystonia

United States
Centre Hospitalier Princesse Grace
Association de Recherche Bibliographique pour les Neurosciences

Completed

Assessment of Empathetic Process by Scanpath Study of an Artwork (EYE-EMPATH)

Parkinson Disease | Alzheimer Dementia | Fronto-Temporal Dementia

Monaco
Hugo W. Moser Research Institute at Kennedy Krieger...

Completed

Rapalogues for Autism Phenotype in TSC: A Feasibility Study (RAPT)

Tuberous Sclerosis Complex | Autism | Self-injury

United States
Samsung Medical Center

Completed

Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia

Spinocerebellar Ataxias | Multiple System Atrophy, Cerebellar Variant (Disorder)

Korea, Republic of
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
Parc Sanitari Pere Virgili
Althaia Xarxa Assistencial Universitària de Manresa; Hospital Vall d'Hebron; Consorci... and other collaborators

Completed

Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease (DIALCAT)

Patients Aged 65-85 (Both Included) | Diagnosed of Mild Cognitive Impairment | Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years

Spain
NeuroActiva, Inc.

Completed

A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831

Neurocognitive Disorders | Neurodegenerative Diseases | Cognitive Impairment | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Alzheimer Dementia | Cognitive Disorder

New Zealand
Herlev Hospital

Completed

Investigation of the Rewarming og the Fingers After Cooling and the Autonomic Nervous System in Raynaud's Phenomenon (RaynAUT)

Glaucoma | Diabetes Mellitus | Parkinson Disease | Autonomic Neuropathy | Raynaud Disease | Raynaud Phenomenon | Autonomic Imbalance | Hand and Arm Vibration Syndrome

Denmark
University College, London
University of Iowa

Unknown

Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study

Charcot-Marie-Tooth Disease, Type IA | Charcot-Marie-Tooth Disease Type 2A | Charcot-Marie-Tooth Disease, Type IB | Charcot-Marie-Tooth Disease, Type X

United Kingdom
Sarcoma Alliance for Research through Collaboration
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

Sarcoma | Neurofibromatosis Type 1

United States
Maastricht University Medical Center
Funding: Stichting Internationaal Parkinson Fonds, The Netherlands

Completed

Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes

Parkinson's Disease | Supranuclear Palsy, Progressive | Multiple System Atrophy | Essential Tremor | Vascular Parkinsonism | Parkinsonian Syndrome | Drug Induced Parkinsonism

Netherlands
Beth Israel Deaconess Medical Center
Biogen

Completed

Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis (CHAMPIONS10)

Multiple Sclerosis | Optic Neuritis | Transverse Myelitis | Acute Brainstem/Cerebellar Syndrome

United States, Canada
National Institute of Mental Health (NIMH)

Completed

Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions

Anorexia Nervosa | Obsessive Compulsive Disorder | Trichotillomania | Tourette Syndrome

United States
Mayo Clinic

Completed

PiB PET Scanning in Speech and Language Based Dementias

Primary Progressive Aphasia | Aphasia | Semantic Dementia | Apraxia of Speech | Primary Progressive Nonfluent Aphasia | PPA | Non-fluent Aphasia | Progressive Aphasia

United States
Mayo Clinic

Completed

Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD

Posterior Cortical Atrophy (PCA) | Atypical Alzheimers Disease | Logopenic Variant of Primary Progressive Aphasia (LPA)

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Completed

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

Tuberous Sclerosis | Subependymal Giant Cell Astrocytoma

United States
National Institute of Neurological Disorders and...

Completed

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

Multiple Sclerosis | Parkinson Disease | Chronic Dysphagia

United States
University Hospital, Bordeaux

Completed

Assessment of Ambulatory Polygraphy in the Detection of Sleep Apnea in Multiple System Atrophy (SAMSA)

Sleep Apnea Syndromes | Multiple System Atrophy

France
Istituto Auxologico Italiano

Recruiting

Advances in Telephone-based Cognitive Screening Procedures (TBCS)

Cerebrovascular Disorders | Amyotrophic Lateral Sclerosis | Frontotemporal Degeneration | Alzheimer's Disease | Lewy Body Dementia

Italy
Conor Fearon
Queen's University

Recruiting

Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism

Ireland
University of Minnesota

Recruiting

Natural History Study for DNA Repair Disorders

DNA Repair Disorder | Xeroderma Pigmentosum | Cockayne Syndrome | Trichothiodystrophy

United States
AC Immune SA
Worldwide Clinical Trials

Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Alzheimer's Disease | Prodromal Alzheimer's Disease | Amyloid Plaque | Beta-Amyloid | Alzheimer's Disease in Down Syndrome

United States, Spain, United Kingdom
Kuopio University Hospital

Recruiting

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

Alzheimer Disease | Frontotemporal Dementia | Dementia With Lewy Bodies

Finland

Clinical Trials on Neurodegeneration

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