Clinical Trials on Neurofibromatosis Type 1 in Germany

Total 4121 results

AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN (SPRINKLE)

Neurofibromatosis Type 1

United States, Spain, Germany, Netherlands, Russian Federation, Italy, Japan
AstraZeneca

Recruiting

PASS of Paediatric Patients Initiating Selumetinib

Neurofibromatosis Type 1

Portugal, Spain, United Kingdom, Israel, France, Italy, Switzerland, Germany, Austria
National Cancer Institute (NCI)

Completed

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Neurofibroma, Plexiform | Neurofibromatosis Type I

United States, Germany
University Hospital Tuebingen
National Center for Tumor Diseases, Heidelberg

Completed

WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data (NF2)

Neurofibromatosis Type 2 | Vestibular Schwannoma | Acoustic Neuroma

Germany
AstraZeneca
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas (KOMET)

Neurofibromatosis 1 | Plexiform Neurofibroma (PN)

United States, Canada, France, Italy, Germany, China, United Kingdom, Spain, Japan, Russian Federation, Australia, Poland, Brazil
Medical University of Vienna
Medical University of Graz; Charite University, Berlin, Germany; Hannover Medical... and other collaborators

Completed

Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")

Sarcoma | Hematologic Diseases | Leukemia | Brain Tumor | Neurofibromatoses | Neuroblastoma

Austria, Germany, Switzerland, Italy
Sanofi

Completed

Euglycemic Clamp Study Comparing Two New Insulin Glargine Formulations in Subjects With Type 1 Diabetes Mellitus

Type1 Diabetes

Germany
Adocia

Completed

A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone® Insulin Lispro, Fiasp® and NovoRapid® Delivered by an Insulin Pump

Type1 Diabetes Mellitus

Germany
Sanofi

Completed

A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus

Type1 Diabetes Mellitus

Germany
Adocia

Completed

A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM

Type 1 Diabetes Mellitus

Germany
Helmholtz Zentrum München

Recruiting

Fr1da-/Fr1da-Plus-Study in Bavaria: Early Detection for Early Care of Type 1 Diabetes (Fr1da-Plus)

Type 1 Diabetes Mellitus

Germany
Adocia

Completed

A Trial to Assess the Efficacy and Safety of M1 Pram P037 Prandial Insulin in Subjects With Type 1 Diabetes (T1DM)

Type 1 Diabetes Mellitus

Germany
Kinderkrankenhaus auf der Bult
Hannover Medical School

Withdrawn

How to be Safe With Alcoholic Drinks in Diabetes (BEER)

Hypoglycemia | Type 1 Diabetes Mellitus

Germany
Biocon Limited
Juvenile Diabetes Research Foundation; Profil Institut für Stoffwechselforschung...

Terminated

Evaluation of Pharmacokinetics , Safety, Tolerability and Pharmacodynamics of Biocon Insulin Tregopil

Type 1 Diabetes Mellitus (T1DM)

Germany
Sanofi

Completed

Single Dose Clamp Study To Compare Concentration/Time Profile And Metabolic Activity Profile Of 2 New Formulations Of Insulin Glargine With Lantus

Type 1 Diabetes Mellitus

Germany
Helmholtz Zentrum München

Recruiting

Freder1k-Study - Testing Infants for Type 1 Diabetes Risk

Identification of Infants at Risk for Type 1 Diabetes

Germany
Dompé Farmaceutici S.p.A

Completed

Reparixin in Pancreatic Islet Transplantation

Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus

Italy, Germany
Mannkind Corporation

Completed

PK and PD Within-Subject Variability of a Single Dose of Afrezza Inhaled Technosphere Insulin in Patients With Diabetes Mellitus Type 1 (T1DM)

Type 1 Diabetes Mellitus

Germany
Hoffmann-La Roche
Roche Diagnostics

Completed

A Study Evaluating the Perception of Insertion Pain With Accu-Chek FlexLink and FlexLink Plus Insulin Pump Devices Under Real Life Conditions in Diabetic Patients.

Diabetes Mellitus Type 2, Diabetes Mellitus Type 1

Germany
Sanofi

Completed

Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

Germany
Technical University of Munich
Ludwig-Maximilians - University of Munich; Technische Universität Dresden; Helmholtz...

Active, not recruiting

Fr1da Insulin Intervention

Stage 1 Diabetes Mellitus, Type 1

Germany
Sanofi

Completed

A Study to Compare Pharmacokinetics (PK) and Pharmacodynamics (PD) of SAR341402 to Insulin Aspart in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Compare BioChaperone Insulin Lispro Formulations With US Approved Humalog® and With EU Approved Humalog® in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Sciema UG

Suspended

Comparative Measurement of Microcirculation and Other Parameters With the Vital USA VitalDetect™ in Patients With Diabetes Mellitus Type 1 and Type 2 Versus Healthy Participants

Diabetes Mellitus

Germany
Sanofi

Completed

A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patients With Type 1 Diabetes

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Adocia

Completed

Blood Glucose Control With BioChaperone Insulin Lispro Compared to Insulin Lispro (Humalog®) After Ingestion of a Standardized Meal

Diabetes Mellitus Type 1

Germany
Adocia
Eli Lilly and Company

Completed

A Trial Investigating the Continuous Subcutaneous Insulin Infusion of a Liquid Formulation of BioChaperone Insulin Lispro in Comparison to Humalog®

Type 1 Diabetes Mellitus

Germany
Hoffmann-La Roche

Completed

Comparison of the Management of Post-prandial Hyperglycemia by Multiple Bolus Calculators

Diabetes Mellitus Type 1

Germany
Kinderkrankenhaus auf der Bult

Completed

Phase 1 Study to Explore the Safety and Pharmacokinetics of DAPAglifozin in Adolescents and Adults With Type 1 Diabetes (DAPA-IIT1)

Type 1 Diabetes

Germany
Adocia

Completed

Postprandial Blood Glucose Control With BioChaperone® Combo and Insulin Lispro (Humalog®) Mix 25 in People With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Sanofi

Completed

Euglycemic Clamp Dose-response Study Comparing a New Insulin Glargine Formulation With Lantus®

Type 1 Diabetes Mellitus

Germany
Institut fur Diabetesforschung, Munich, Germany

Unknown

BABYDIET-Study - Primary Prevention of Type 1 Diabetes in Relatives at Increased Genetic Risk

Type 1 Diabetes

Germany
Adocia
Tonghua Dongbao Pharmaceutical Co.,Ltd

Completed

A Trial Comparing the Pharmacodynamics and Pharmacokinetics of BC Combo THDB0207 and Lantus® and Humalog® in Subjects With Type 1 Diabetes

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Sanofi

Completed

Study of How Single Rising Doses of SAR161271 Are Absorbed and Act in Patients With Type 1 Diabetes Mellitus (T1DM)

Type 1 Diabetes Mellitus

Germany
Kinderkrankenhaus auf der Bult

Completed

Use of an Automated Insulin Delivery System Compared to Sensor Augmented Pump at Patients With Type 1 Diabetes (T1D) (DREAM5)

Type 1 Diabetes

Germany
Hoffmann-La Roche

Completed

A Monocenter, Open-Label Glucose Clamp Study Examining the Metabolic Effect of Insulin Infusion Intervals for Basal Insulin Infusion in Patients With Type I Diabetes

Diabetes Mellitus Type 1

Germany
Perosphere Pharmaceuticals Inc, a wholly owned...
Profil Institut für Stoffwechselforschung GmbH

Withdrawn

Pharmacokinetics of Ultra-Rapid-Acting Insulin Lispro (URAL) in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Hoffmann-La Roche

Completed

Comparison of Basal (Fasting) Glycemic Control in Type 1 Diabetic Patients With CSII Achieved by the Circadian Slide Ruler Scale or Flat Basal Rate

Diabetes Mellitus Type 1

Germany
Biodel

Completed

A Study Evaluating the Bioequivalence of VIAject®7 Compared to VIAject®25 and Comparing the Pharmacokinetic and Pharmacodynamic Properties of VIAject®7 to Insulin Lispro in Subjects With Type 1 Diabetes Mellitus

Diabetes Mellitus

Germany
Sanofi

Completed

A Study to Compare Pharmacokinetics and Pharmacodynamics of SAR342434 to Insulin Lispro in Subjects With Type 1 Diabetes

Type 1 Diabetes

Germany
Institut fur Diabetesforschung, Munich, Germany

Completed

Immunointervention With Calcitriol in New-Onset Type 1 Diabetes

Type 1 Diabetes

Germany
Sanofi

Completed

Comparison of Exposure and Activity of SAR341402 Mix 70/30 to NovoLog Mix 70/30, NovoMix 30 and SAR341402 Rapid-acting Solution in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Assess Safety and Efficacy of ADO09 Versus Insulin Aspart in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Novo Nordisk A/S

Completed

Study on How Fiasp® Can Influence Blood Sugar Levels of type1 Diabetic Patients in Their Daily Lives, With the Help of the Freestyle Libre® Device (GoBolus)

Diabetes | Diabetes Mellitus, Type 1 Diabetes

Germany
Sanofi

Completed

Repeated Dosing Study With a New Insulin Glargine Formulation and Lantus® in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Sanofi

Completed

Relative Bioavailability and Activity of Different Formulations of Insulin Glargine and Lixisenatide in Patients With Diabetes Mellitus Type 1

Type 1 Diabetes Mellitus

Germany
Kinderkrankenhaus auf der Bult
AstraZeneca; Alcedis GmbH

Completed

Pilot Study to Explore the Efficacy of DAPAglifozin as add-on to Closed-loop Control in Patients With Type 1 Diabetes (DapaDream)

Type1diabetes

Germany
Adocia

Completed

A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany

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