Clinical Trials on Niemann-Pick Disease, Type A

Total 58435 results

Newcastle University
Bill and Melinda Gates Foundation; Institute of Nutrition of Central America... and other collaborators

Unknown

Liver and Bone Retinol Levels in Guatemalan Adolescents and Adults (GVAS)

Vitamin A Deficiency | Vitamin A Toxicity | Hypervitaminosis A

Guatemala, United Kingdom
Gazi University

Not yet recruiting

The Effect of Relaxation Program on Coping With Stress and Anxiety Levels of Caregivers of Children With Cancer.

Caregivers With a Child Followed up With a Cancer Diagnosis

Turkey
AZ-VUB

Unknown

An Explorative Study of Afatinib in the Treatment of Advanced Cancer Carrying an EGFR, a HER2 or a HER3 Mutation

Cancers Harbouring an EGFR Mutation, (Excluding Non-squamous Non- Small Cell Lung Cancer, a Registered Indication), a HER2 Mutation or a HER3 Mutation

Belgium
Novartis Pharmaceuticals

Completed

BKM120 for Patients With PI3K-activated Tumors (SIGNATURE)

PI3K Pathway Activated Tumors

United States
Sanwa BioTech Limited
Chinese University of Hong Kong; Prince of Wales Hospital, Shatin, Hong Kong

Not yet recruiting

Influenza A+B Test Kit Performance Study

Influenza Type B | Influenza Type A

Hong Kong
SAb Biotherapeutics, Inc.

Active, not recruiting

Safety, Tolerability, and Pharmacokinetics of SAB-176 in Healthy Participants

Influenza | Influenza Type B | Influenza Type A

United States
Peking University People's Hospital

Withdrawn

Interferon-α Prevents Leukemia Relapse of AML Patients After Transplantation

Relapse | Prevention | Interferon-A-2B | Hematopietic Stem Cell Transplantation

China
Akcea Therapeutics

Completed

Drug-drug Interaction Study to Evaluate the Effect of ISIS 681257 on Warfarin

Cardiovascular Diseases | Elevated Lipoprotein(a)

Canada
Akcea Therapeutics

Completed

Drug-drug Interaction Study to Evaluate the Effect of ISIS 681257 on Clopidogrel

Cardiovascular Diseases | Elevated Lipoprotein(a)

Canada
Christoph Königs
Roche Pharma AG; Chugai Pharma Germany GmbH

Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab (NAVIGATE)

Severe Hemophilia A | Severe Hemophilia A With Inhibitor | Severe Hemophilia A Without Inhibitor

Germany
Medical Corps, Israel Defense Force

Completed

Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever

Jarisch Herxheimer Reaction | Relapsing Fever, Tick-Borne

Israel
University Hospital, Brest

Unknown

COMPLI-PICC: Study on Picclines' Complications (COMPLI-PICC)

PICC Line Placement

France
Novartis Vaccines

Completed

Safety and Long-term Evaluation (up to 5 Years) of First Booster Immunization With Novartis' TBE Vaccine for Adults in Adolescents and Adults

Tick Born Encephalitis

Czech Republic
Region Västerbotten
Umeå University; Mahidol University

Completed

Muscle Weakness Duration After Single Botulinum Toxin Injection in Masseter

Botulinum Toxins, Type A | Bite Force

Sweden
Centre Hospitalier Universitaire Dijon

Terminated

Treatment With Continuous Sub-cutaneous Insulin Infusion Via a Portable Pump Versus Discontinuous Insulin Infusion Via Multiple-injections in Type 2 Diabetes (TRICIDIA)

Patient With Type 2 Diabetes Treated With Insulin Using a Baseline/Bolus Strategy

France
Fresenius Medical Care Deutschland GmbH

Completed

Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter (LINET)

Hypercholesterolemia, Familial | LIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA

Germany
Technische Universität Dresden
Kaneka Pharma Europe N.V.

Recruiting

Effect of Lipoprotein(a) Elimination by Lipoprotein Apheresis on Cardiovascular Outcomes (MultiSELECt)

Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Germany
Aalborg University

Completed

Characterization of New Human Models of Non-histaminergic Itch

Itch | Papain | Skin Prick Test (SPT)

Denmark
QIAGEN Gaithersburg, Inc

Completed

Collection and Testing of Respiratory Samples

Respiratory Syncytial Virus Infections | Influenza A | Rhinovirus | Influenza B | QIAGEN ResPlex II Advanced Panel | Infection Due to Human Parainfluenza Virus 1 | Parainfluenza Type 2 | Parainfluenza Type 3 | Parainfluenza Type 4 | Human Metapneumovirus A/B | Coxsackie Virus/Echovirus | Adenovirus Types B/C/E | Coronavirus Subtypes 229E and other conditions

United States
St. Jude Children's Research Hospital
National Institute of Allergy and Infectious Diseases (NIAID); The University...

Completed

Surveillance of Influenza Virus Among Children With Febrile Respiratory Complaints Attending the Pediatric Clinic of the First Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, Mainland China

Influenza Type B | Influenza Type A

China
Noordwest Ziekenhuisgroep
Karolinska Institutet; Medical University of Graz; Fondazione Policlinico Universitario... and other collaborators

Recruiting

Paediatric European Group A Streptococcal United Study. (PEGASUS)

Invasive Group A Beta-Haemolytic Streptococcal Disease

Netherlands
Tampere University Hospital
Turku University Hospital; University of Turku

Active, not recruiting

Invasive Disease Caused by Group A Streptococcus (GAS) (DICAR) (DICAR)

Invasive Group A Beta-Haemolytic Streptococcal Disease

Finland
VTT Technical Research Centre of Finland
Social Insurance Institution, Finland; Finnish Institute for Health and Welfare and other collaborators

Completed

Pharmacogenomics of Antithrombotic Drugs -a Register Linkage Study With National Registries and Biobanks in Finland

Individuals With a Disease of Cardiovascular System

Finland
West China Hospital

Unknown

Antegrade Cerebral Perfusion and Retrograde Inferior Vena Caval Perfusion for Total Aortic Arch Replacement (CARTAR)

Hypothermia | Circulatory Arrest | Type A Aortic Dissection

China
Military Institute od Medicine National Research...

Completed

Predictive Value of Early Changes of Chromogranin A Levels in Patients With Neuroendocrine Tumours Treated With PRRT

Early Release of Chromogranin A (CgA)
Masonic Cancer Center, University of Minnesota

Recruiting

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

Hurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Metachromatic Leukodystrophy | Alpha-Mannosidosis | Hunter Syndrome | Mucopolysaccharidosis Disorders | Maroteaux Lamy Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Glycoprotein Metabolic Disorders | Recessive Leukodystrophies | Globoid... and other conditions

United States
GlaxoSmithKline

Completed

The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine

Virus Diseases

Czechia
Children's National Research Institute
Steven & Alexandra Cohen Foundation; Clinical Trials Network for Lyme and Other...

Recruiting

Navigating Pregnancy and Parenthood With Lyme Disease

Pregnancy Complications | Parenting | Tick-Borne Diseases | Lyme Disease | Chronic Lyme Disease | Tick-Borne Infections | Post Treatment Lyme Disease

United States
Medical Corps, Israel Defense Force

Not yet recruiting

Postexposure Prophylaxis With Single Dose Doxycycline for the Prevention of Tick-borne Relapsing Fever

Relapsing Fever, Tick-Borne
Mayo Clinic

Completed

Feasibility Trial of the Early Psychological Support for the Critically Ill

PICS

United States
Hospital Sao Domingos

Completed

The Impact of a Bundle of Preventive Measures for Post-intensive Care Syndrome on the Outcome of Critically Ill Patients

PICS

Brazil
Radboud University Medical Center
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Academisch... and other collaborators

Unknown

Anti-T-Lymphocyte Globulin (ATG) in Renal Transplantation of Kidneys With a Non-Heart-Beating (NHB) Donor (ATG)

Renal Transplant Patients | Recipients of a Kidney From a Non-Heart-Beating Donor

Netherlands
University Hospital, Grenoble

Completed

Cost and Effectiveness of Pressurized Intraperitoneal Aerosol Chemotherapy in Patients With Peritoneal Carcinoma. (PIPAC-GRE)

Evaluate the Cost of a PIPAC Procedure and the Associated Hospital Stay in France

France
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
Weill Medical College of Cornell University

Unknown

Advanced Imaging Registry for Diagnosing Pancreatico-biliary Disorders

Diagnosis of a Pancreaticobiliary Disorder

United States
First Affiliated Hospital Xi'an Jiaotong University

Completed

Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )

Type A Aortic Dissection

China
Novartis Pharmaceuticals

Completed

Lipoprotein(a) in Patients With Cardiovascular Disease (CVD)

Cardiovascular Disease and Lipoprotein(a)

China, Germany, United States, Colombia, South Africa, Italy, Spain, Belgium, Egypt, Hungary, Taiwan, Turkey, Japan, Netherlands, Australia, Austria, Canada, Czechia, France, Israel, Switzerland, United Kingdom, Korea, Republic of, Th... and more
Sohag University

Recruiting

Holter Monitoring of Critically-ill Childern in PICU at Sohag University Hospital

Critically Ill Childern in PICU

Egypt
Novo Nordisk A/S

Recruiting

A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors

Haemophilia A With Inhibitors | Haemophilia A

United States, Korea, Republic of, France, Spain, Romania, Canada, Taiwan, China, Lithuania, Netherlands, India, South Africa, Russian Federation, Austria, Belgium, Czechia, Denmark, Germany, Ireland, Italy, Japan, Latvia, Malaysia, M... and more
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis (Beyond ABR)

Severe Hemophilia A | Moderate Hemophilia A

Brazil, Germany, Italy, Spain, United States, Turkey, United Kingdom, Tunisia, Canada, Hungary, Morocco, Serbia
Duke University
David Grant U.S. Air Force Medical Center

Completed

Genetically Guided Statin Therapy

Hypercholesterolemia | Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction

United States
Changi General Hospital

Not yet recruiting

Elevated Lipoprotein(a) in Hospital Staff (LPACO)

Cardiovascular Diseases | Hypercholesterolemia | Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Singapore
CSL Behring

Withdrawn

A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line

PICC-associated Thrombosis
JW Pharmaceutical

Recruiting

The Safety of Emicizumab SC Injection in Korean Hemophilia A Patients With/Without FVIII Inhibitors

Hemophilia A With Inhibitor | Hemophilia A Without Inhibitor

Korea, Republic of
School of Medicine. National University of Cuyo

Recruiting

Argentine Registry of Lp(a) (GAELpa)

Cardiovascular Diseases | Hypertension | Hypercholesterolemia | Diabete Type 2 | Lp(A)

Argentina
Novo Nordisk A/S

Recruiting

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4) (FRONTIER4)

Haemophilia A With Inhibitors | Haemophilia A

Taiwan, Canada, Spain, Netherlands, Korea, Republic of, India, United States, United Kingdom, China, Portugal, Lithuania, Turkey, South Africa, Ireland, Italy, France, Japan, Belgium, Germany, Malaysia, Poland, Austria, Bulgaria, Denmark and more
Novo Nordisk A/S

Active, not recruiting

A Research Study Looking at How Safe it is to Switch From Emicizumab to Mim8 in People With Haemophilia A (FRONTIER 5) (FRONTIER 5)

Haemophilia A With Inhibitors | Haemophilia A

Spain, Korea, Republic of, Canada, United Kingdom, United States, Germany, South Africa, Italy, Austria, Belgium, France, Japan
GWT-TUD GmbH
Hannover Medical School; Hoffmann-La Roche

Completed

Emicizumab in Acquired Hemophilia A

Hemophilia A, Acquired

Austria, Germany
University Hospital, Strasbourg, France

Unknown

Randomised Study Comparing Discharge 3 Days After Surgery to Home Within 24 Hours After Laparoscopic Hysterectomy.

Women Who Undergo a Laparoscopic Hysterectomy for Benign Disease.

France
University of Pennsylvania

Completed

The Effect of a Coloring Prompt on Health Engagement

In Need of a Pap Smear (Cervical Cancer Screening) | In Need of a Blood Pressure Check (Hypertension Screening) | In Need of a Cholesterol Test (Lipid Disorder Screening) | In Need of a Fasting Plasma Glucose Test (Diabetes)

United States

Clinical Trials on Niemann-Pick Disease, Type A

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in United Arab Emirates

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Rare Diseases

Drug Interventions

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