Clinical Trials on Non-Hyponatremia

Total 16897 results

Vibeke Moen

Completed

Do Changes in Plasma Osmolality Influence Ventilation? (OSM)

Hypernatraemia | Hyponatraemia

Sweden
Otsuka Frankfurt Research Institute GmbH

Unknown

Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice

SIADH | Non-SIADH Hyponatremia | Non-Hyponatremia

Denmark, Germany, Italy, Norway, Spain, Sweden, United Kingdom
Dokuz Eylul University
Cukurova University; Kanuni Sultan Suleyman Training and Research Hospital; Baskent... and other collaborators

Completed

Comparison of the Isotonic and Hypotonic Intravenous Maintenance Fluids In Term Newborns: Neofluid Study (NEOFLUID)

Fluid Therapy | Newborn Complication | Isotonic Dehydration | Hyponatremia of Newborn | Hypernatremia of Newborn | Sodium Chloride

Turkey
Hamilton Health Sciences Corporation

Completed

Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial

Hyponatremia | Hypernatremia

Canada
Jiangsu HengRui Medicine Co., Ltd.
Beijing Friendship Hospital; Beijing 302 Hospital; Beijing Anzhen Hospital

Unknown

Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

Non-hypovolemic Non-acute Hyponatremia

China
University of Cologne

Recruiting

Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial (EvenT)

Non-hypervolemic Hyponatremia

Germany
University of Oulu
Oulu University Hospital

Completed

Intravenous Fluids in Hospitalised Children

Hyponatremia | Dehydration | Hypokalemia | Hypernatremia

Finland
University Hospital Inselspital, Berne
Steering committee of the NCCR

Withdrawn

Frequency and Origin of Dysnatremias in the Emergency Department

Hyponatremia | Hypernatremia
University Hospital, Linkoeping

Recruiting

Plasma Sodium and Sodium Administration in the ICU

Critical Illness | Hyponatremia | Hypernatremia

Sweden
University Hospital, Basel, Switzerland
Kantonsspital Aarau

Completed

Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients (COMED)

Hyponatremia | Hypernatremia

Switzerland
Oakland University
Georgetown University

Completed

V2 Receptor Effects on Fluid Regulation and Performance

Hyponatremia | Hypernatremia | Electrolyte Imbalance

United States
Otsuka America Pharmaceutical
Registrat-Mapi

Completed

Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia (HN Registry)

Euvolemic Hyponatremia | Hypervolemic Hyponatremia

United States, United Kingdom, Germany
University Hospital, Basel, Switzerland

Not yet recruiting

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Thiazide Associated Hyponatremia

Switzerland
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Samsca Post Marketing Surveillance Study (Samsca PMS)

Hypervolemic and Euvolemic Hyponatremia

Korea, Republic of
Hospital Italiano de Buenos Aires
Sociedad Argentina de Hipertension Arterial (SAHA)

Completed

Polymorphisms of the Thiazide's Receptor Gene SLC12A3 and Development of Hyponatremia

Thiazide Diuretics Induced Hyponatremia

Argentina
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia

Euvolemic Hyponatremia

United States, Israel, India, Mexico, Peru, Belgium, Czech Republic, Italy
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430

Hyponatremia With Excess Extracellular Fluid Volume | Hyponatremia With Normal Extracellular Fluid Volume

United States
Western States Endurance Run Research Foundation

Unknown

The Efficacy of Oral Versus Intravenous Hypertonic Saline Administration in Runners With Exercise-Associated Hyponatremia

Exercise-associated Hyponatremia

United States
University Hospital, Basel, Switzerland

Recruiting

Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia (PROPHECY)

Thiazide-induced Hyponatremia (TIH)

Switzerland
Azienda Ospedaliera Città della Salute e della...

Completed

Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status

Hyponatremia | Hyponatremia With Excess Extracellular Fluid Volume | Hyponatremia With Extracellular Fluid Depletion | Hyponatremia With Normal Extracellular Fluid Volume

Italy
Seoul National University Hospital
National Research Foundation of Korea

Completed

Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients

Hyponatremia Symptomatic

Korea, Republic of
Assiut University

Completed

Hyponatremia in Elderly Patients With Fractures Around the Hip.

Hyponatremia in Elderly

Egypt
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia

Hyponatremia With Normal Extracellular Fluid Volume

United States, Canada, Germany, India, Poland, Belgium
Otsuka Beijing Research Institute
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

Hypovolemic Hyponatremia

China
Korea Otsuka Pharmaceutical Co., Ltd.

Terminated

Effect of Samsca on Control of Hyponatremia and Extracellular Fluid in Cirrhotic Patients With Ascites (ECF)

Hyponatremia and Extracellular Fluid in Cirrhotic

Korea, Republic of
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Withdrawn

International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia

Hypervolemic Hyponatremia
Korea Otsuka Pharmaceutical Co., Ltd.

Terminated

Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure (AQUATIC)

Heart Failure With Hyponatremia

Korea, Republic of
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Inappropriate ADH Syndrome | Water Intoxication | Hyponatremias | Water-Electrolyte Imbalances

United States
Washington University School of Medicine

Active, not recruiting

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) (DHAPS)

Surgery | Hyponatremia | Pituitary | Pituitary Tumor | Hyponatremic

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia: a Multicenter Open-label Randomized Controlled Trial (DASSOH)

Hyponatremia
Universidad Veracruzana

Recruiting

Hyponatremia Volume Status Analysis by Point-of-care Ultrasound (Vostaus)

Hyponatremia | Water-Electrolyte Imbalance

Mexico
Camilo Jose Cela University

Completed

Effects of Oral Salt Supplementation on Physical Performance During a Half-ironman (SALTED)

Hyponatremia

Spain
University of Cologne

Completed

Characterisation of Neuropsychological and Motoric Performance in Patients With Hyponatremia

Hyponatremia

Germany, Spain, Italy
Tazeen Rasheed

Completed

Hyponatremia Due to Poly Ethylene Glycol (PEG)

Hyponatremia

Pakistan
Bürgerspital Solothurn

Terminated

Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function

Hyponatremia

Switzerland
Diego Hernan Giunta, MD

Unknown

Factors Associated With Hyponatremia Induced by High-dose Cyclophosphamide

Hyponatremia

Argentina
Karolinska University Hospital

Terminated

Hyponatremia and Myometrium Contractility. An Invitro Study

Hyponatremia

Sweden
Cumberland Pharmaceuticals
Parke-Davis

Completed

Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

Poland, United Kingdom, Germany, Spain, Belgium, France, Netherlands, Italy, Finland
Cumberland Pharmaceuticals

Completed

An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

South Africa, United States, Israel
Queen's University
Ferring Pharmaceuticals

Completed

Pico-Salax Colonic Preparation Study: Quantifying Electrolyte and Volume Status Changes

Hyponatremia | Hemodynamics

Canada
Medical Centre Leeuwarden
University Medical Center Groningen

Completed

Balance Study on ICU-acquired Hypernatremia and Sodium Handling (BIAS) (BIAS)

ICU-acquired Hypernatremia

Netherlands
University Hospital, Basel, Switzerland

Recruiting

Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients (BONA)

Hyponatremia

Switzerland
Northwestern University
Astellas Pharma US, Inc.

Terminated

Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients

Hyponatremia
Hospital Italiano de Buenos Aires

Completed

Institutional Registry of Hyponatremia (Hyponatremia)

Hyponatremia

Argentina
Postgraduate Institute of Medical Education and...

Unknown

Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children

Hyponatremia

India
University Hospital of Cologne

Completed

Influence of Triathlon on the Electrolyte Balance (Ironman)

Hyponatremia

Germany
Cumberland Pharmaceuticals
Astellas Pharma US, Inc.

Completed

Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

United States, South Africa, Israel, Canada
The Hospital for Sick Children

Completed

0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children

Hyponatremia

Canada
Thomas Jefferson University
Bausch Health Americas, Inc.

Completed

Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS

Hyponatremia

United States
University Hospital, Caen

Completed

Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy? (NATRIPHAR)

Hyponatremia

France

Clinical Trials on Non-Hyponatremia

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