Clinical Trials on Non-metastasized Unresectable Pancreatic Carcinoma

Total 7959 results

Tocagen Inc.

Terminated

A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)

Melanoma | Sarcoma | Lymphoma | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | IDH1 Mutated Solid Tumors | IDH1 Mutated or MGMT Methylated Recurrent HGG (Not Recruiting)

United States
University of Nebraska
Bracco Diagnostics, Inc; Philips Medical Systems

Completed

Rapid 10-Minute Liver MRI Protocol in Patients With Suspected Hepatocellular Carcinoma

Hepatitis | Fibrosis of Liver | Underlying Liver Disease | Cirrhosis With Suspicion of Liver Cancer | Lesion on a Prior Ultrasound, CT or Outside MRI

United States
Transgene
Merck Sharp & Dohme LLC; BioInvent International AB

Recruiting

A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors

Melanoma | Soft Tissue Sarcoma | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Merkel Cell Carcinoma

France, Belgium
Pfizer

Terminated

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Melanoma | Sarcoma | Head and Neck Cancer | Colorectal Cancer | Ovarian Cancer | Bladder Cancer | Renal Cell Cancer | Hepatocellular Cancer | Squamous Cell Carcinoma | Non-Small-Cell Lung Cancer

United States
Daiichi Sankyo, Inc.
Merck Sharp & Dohme LLC; Plexxikon

Terminated

A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors

Melanoma | Ovarian Cancer | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Gastrointestinal Stromal Tumor (GIST)

United States
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Melanoma (Skin) | Carcinoma of Unknown Primary

United States
Seagen Inc.

Completed

Safety Study of SGN-CD70A in Cancer Patients

Renal Cell Carcinoma | Diffuse, Large B-Cell, Lymphoma | Mantle-Cell Lymphoma | Follicular Lymphoma, Grade 3

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions

United States
Yonsei University

Unknown

Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient

Klatskin Tumor | Biliary Obstructive Disease Such as Choledocholithiasis | Benign Biliary Stricture | Peri-ampullary Cancer | Bile Duct Cancer Resectable

Korea, Republic of
Inovio Pharmaceuticals
Mayo Clinic; University of Pennsylvania; University of Pittsburgh; Thomas Jefferson... and other collaborators

Completed

hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse (TRT-001)

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | ColoRectal Cancer | HepatoCellular Carcinoma

United States
Neonc Technologies, Inc.

Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Gastroesophageal Junction... and other conditions

United States
Duke University

Recruiting

Onco-primary Care Networking to Support TEAM-based Care (ONE TEAM)

Hypertension | Diabetes Mellitus | Diabetes | Cancer | Blood Pressure | Hypercholesterolemia | Non Small Cell Lung Cancer | Cancer of Head and Neck | Cancer of Liver | Cancer, Breast | Cancer of Pancreas | Cancer Colorectal | Cancer of Prostate | Cancer of Esophagus | Cancer, Endometrial | CVD - Cardiovascular Disease | Cancer... and other conditions

United States
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Seagen Inc.
Genmab

Completed

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Prostate Cancer | Squamous Cell Carcinoma of the Head and Neck | Bladder Cancer | Cervix Cancer | Lung Cancer, Nonsmall Cell | Ovary Cancer | Esophagus Cancer | Endometrium Cancer

United States, United Kingdom
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Lymphoma | Kidney Cancer | Pancreatic Cancer | Esophageal Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Intraocular Melanoma | Melanoma (Skin) | Transitional Cell Cancer of the Renal Pelvis and Ureter

United Kingdom
Ludwig Institute for Cancer Research
Cancer Research Institute, New York City; MedImmune LLC

Completed

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Melanoma | Sarcoma | Breast Cancer | Solid Tumor | Prostate Cancer | Bladder Cancer | Head and Neck Squamous Cell Carcinoma | Cutaneous T-Cell Lymphoma | Renal Cancer | Merkel Cell Carcinoma | Testicular Cancer

United States
Celgene

Completed

Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies

Melanoma | Sarcoma | Neoplasms | Lymphoma | Renal Cell Carcinoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Breast Cancer | Small Cell Lung Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Non-Small Cell Lung Cancer | Osteosarcoma | Glioblastoma Multiforme | Metastatic Breast... and other conditions

United States
Jonsson Comprehensive Cancer Center
Telix Pharmaceuticals (Innovations) Pty Limited

Not yet recruiting

An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer

Clear Cell Renal Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Recurrent Clear Cell Renal Cell Carcinoma | Stage II Renal Cell Cancer American Joint Committee on Cancer...

United States
Istanbul Medeniyet University

Recruiting

The Effect of Post-voiding Reisdual Urine on Non-muscle Invasive Bladder Cancer Recurrence and Progression

Bladder Cancer Recurrent | Non-Invasive Bladder Urothelial Carcinoma

Turkey
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Terminated

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

Sarcoma | Glioblastoma | Recurrent Ovarian Carcinoma | Recurrent Uterine Corpus Carcinoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Metastatic Renal Cell Cancer | Recurrent Lung Carcinoma | Recurrent Renal Cell Carcinoma | Stage IV Skin Melanoma | Recurrent Melanoma | Stage IIIB Skin Melanoma | Stage... and other conditions

United States
Qilu Hospital of Shandong University

Recruiting

Efficacy and Safety of Pseudomonas Aeruginosa for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Bladder Cancer

China
Guangdong Association of Clinical Trials

Not yet recruiting

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Carcinoma, Non-Small-Cell Lung | Brain Metastases | Leptomeningeal Metastasis

China
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
Rigshospitalet, Denmark

Completed

Why in Hospital After VATS Lobectomy

Pain, Postoperative | Carcinoma, Non-Small-Cell Lung | Atrial Fibrillation | Postoperative Nausea and Vomiting | Infection | Air Leakage

Denmark
Kidney Cancer Research Bureau

Unknown

Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion.

Non-small Cell Lung Cancer Metastatic | Pleural Effusion, Malignant | Renal Cell Cancer Metastatic

Russian Federation
Shandong Cancer Hospital and Institute
AstraZeneca

Unknown

Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M

Nonsmall Cell Lung Cancer | Brain Metastases | EGFR-TKI Resistant Mutation | AZD9291
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

SU5416 in Treating Patients With Advanced or Recurrent Cancer of the Head and Neck

Head and Neck Cancer | Non-melanomatous Skin Cancer | Carcinoma of Unknown Primary

United States
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
Lei Li

Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis | ROMA Index

China
Immunophotonics, Inc.

Recruiting

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS (INJECTABL-1)

Soft Tissue Sarcoma | Nonsmall Cell Lung Cancer | Metastatic Solid Tumor | Colon Cancer

France, United Kingdom, United States, Germany, Switzerland
Compass Therapeutics
Iqvia Pty Ltd; Merck, Sharp & Dohme, LLC, Rahway, NJ USA

Recruiting

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

Melanoma | Head and Neck Cancer | Small Cell Lung Cancer | Metastatic Cancer | Mesothelioma | Non-small Cell Lung Cancer | Locally Advanced Solid Tumor

United States
Daiichi Sankyo Co., Ltd.

Completed

An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors

Cervical Cancer | Small Cell Lung Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Gastric Cancer (Inoperable and Recurrent)

Japan
McMaster University

Not yet recruiting

A Comparison of Skin Grafts Versus Local Flaps for Facial Skin Cancer From the Patient Perspective: A Feasibility Study

Skin Cancer | Patient Satisfaction | Skin Cancer, Basal Cell | Skin Cancer, Non-Melanoma | Skin Cancers - Squamous Cell Carcinoma
Intensity Therapeutics, Inc.
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01)

Sarcoma | Lymphoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Bile Duct Cancer | Colon Cancer | Liver Cancer | Squamous Cell Carcinoma | Chordoma of Sacrum

United States, Canada
Dicerna Pharmaceuticals, Inc.

Terminated

Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma

Multiple Myeloma | PNET | Solid Tumors | Non-Hodgkins Lymphoma | NHL | Pancreatic Neuroendocrine Tumors

United States
German Breast Group
Roche Pharma AG; Amgen; Teva Pharmaceuticals USA; Vifor Pharma

Completed

A Phase III Trial Comparing Two Dose-dense, Dose-intensified Approaches (ETC and PM(Cb)) for Neoadjuvant Treatment of Patients With High-risk Early Breast Cancer (GeparOcto)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Northwestern University
National Cancer Institute (NCI)

Completed

Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Intestine Cancer | Ovarian Cancer | Peritoneal Cavity Cancer | Gastrointestinal Stromal Tumor | Extrahepatic Bile Duct Cancer | Nausea and Vomiting | Constipation, Impaction, and Bowel Obstruction

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas

Lymphoma | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
German Breast Group
Celgene Corporation; Amgen

Completed

Denosumab as an add-on Neoadjuvant Treatment (GeparX) (GeparX)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
National Cancer Institute (NCI)

Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

Malignant Solid Neoplasm | Acute Myeloid Leukemia | Multiple Myeloma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer... and other conditions

United States, Puerto Rico
Jinming Yu

Recruiting

A Phase Ib Study of TQB2450 Combined With Anlotinib in Patients With Limited Stage Small Cell Lung Cancer After First-line Radiotherapy and Chemotherapy

Limited Stage Small Cell Lung Cancer | Not Progressed After First-line Chemoradiotherapy

China
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
Yang Yang

Unknown

PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated Malignancies

Stage IV Adult Hodgkin Lymphoma | Stage IV Nasopharyngeal Carcinoma | Stage IV Diffuse Large B-Cell Lymphoma | Stage IV Gastric Carcinoma | T-Cell Lymphoma Stage IV

China
Seagen Inc.

Recruiting

A Study of SGN-B7H4V in Advanced Solid Tumors

Carcinoma, Non-Small-Cell Lung | Adenoid Cystic Carcinoma | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Endometrial Neoplasms | Cholangiocarcinoma | Triple Negative Breast Neoplasms | Gallbladder Carcinoma | HER2 Negative Breast Neoplasms | Hormone Receptor Positive Breast Neoplasms

United States, Spain, Canada, United Kingdom, Germany, Italy
Alaunos Therapeutics

Active, not recruiting

Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Cholangiocarcinoma | Adenocarcinoma of Lung | Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Ovary Neoplasm | Adenosquamous Cell Lung Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy (HYPOGRYPHE)

Melanoma | Renal Cell Carcinoma | NSCLC | SCLC | Breast Carcinoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Brain Metastases, Adult

United States
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016)

Carcinoma, Hepatocellular | Colorectal Neoplasms | Esophageal Neoplasms | Endometrial Neoplasms | Pancreatic Ductal Adenocarcinoma | Biliary Tract Neoplasms

Israel, United States, Australia, Belgium, Chile, France, Korea, Republic of, Netherlands, Spain, New Zealand
Imunon
Philips Healthcare

Withdrawn

MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases

Adenocarcinoma | Small Cell Lung Cancer | Breast Carcinoma | Non-small Cell Lung Cancer | Painful Bone Metastases
Totus Medicines

Recruiting

A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With Select Solid Tumors

Cervical Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Squamous Cell Carcinoma of Head and Neck | Endometrial Cancer | Non-small Cell Lung Cancer | Urothelial Carcinoma | HER2-negative Breast Cancer

United States

Clinical Trials on Non-metastasized Unresectable Pancreatic Carcinoma

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