Clinical Trials on Nonhematologic Malignancies

Total 1424 results

Joanne Kurtzberg, MD
Miltenyi Biomedicine GmbH

Completed

Unrelated Cord Blood Transplant Plus a Haplo-Identical (Half-Matched), T-Cell Depleted Stem Transplant From a Related Donor for Subjects With High Risk Malignancies

Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndrome (MDS)

United States
Memorial Sloan Kettering Cancer Center

Completed

Improving Functional Outcomes in Patients With Unilateral Vocal Cord Paralysis: Assessment of Adaptation Using Functional Magnetic Resonance Imaging

Unilateral Vocal Cord Paralysis | Intrathoracic Malignancies

United States
The Children's Hospital of Zhejiang University...
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Anhui Provincial Hospital
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies

Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk

China
Monash University

Recruiting

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (RATIONALISE)

Hypogammaglobulinemia | Haematological Malignancy

Australia
Centre Hospitalier Universitaire de Nīmes

Recruiting

Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies. (TIPHI)

Leukemia | Chronic Leukemia | Myelogenous Leukemia | BCR-ABL Positive Acute Myeloid Leukemia

France
Marcela V. Maus, M.D.,Ph.D.

Completed

CAR-37 T Cells In Hematologic Malignancies

Lymphoma | Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Leukemia | Lymphoma, T-Cell | Hematologic Malignancy

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)

Mature B-cell Neoplasms

Japan
Ariad Pharmaceuticals

Completed

Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignancies

Chronic Myelogenous Leukemia | Hematologic Malignancies

United States
Rambam Health Care Campus

Unknown

Effect of Smartphone App on Activity

Hematologic Malignancy | Diabetes Type 2

Israel
Memorial Sloan Kettering Cancer Center

Completed

Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation

Hematologic Malignancies | Streptococcal Sepsis

United States
Epizyme, Inc.

Completed

Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer

Solid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)

Spain, United States
AvenCell Europe GmbH
Allucent (NL) BV

Recruiting

Dose-escalating Trial With Allo-RevCAR01-T Cells in Combination With CD123 Target Module (R-TM123) for Participants With Selected Hematologic Malignancies Positive for CD123

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

Germany, Netherlands
Universidad de Sonora
Hospital Civil de Guadalajara; International Atomic Energy Agency; Centro de...

Recruiting

Body Composition and Nutritional Status in Pediatric Patients With Hematological Malignancies (HM)

Childhood Obesity | Childhood Cancer | Child Malnutrition

Mexico
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Weill Medical...

Completed

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies (SCENE)

Neutropenia | Hematologic Malignancy | Bloodstream Infection | Leukemia, Acute

United States
Medical College of Wisconsin

Terminated

Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Leukemia | Chronic Leukemia

United States
Millennium Pharmaceuticals, Inc.

Terminated

A Study of TAK-164 in Participants With Advanced Gastrointestinal (GI) Cancer Expressing Guanylyl Cyclase C (GCC)

Gastrointestinal Neoplasms; Esophageal, Stomach, Pancreas, Colon Neoplasms; Malignant Tumors of Digestive Organ; Advanced Gastrointestinal Malignancies

United States
Columbia University
Celgene

Terminated

Romidepsin Plus Oral 5-Azacitidine in Relapsed/Refractory Lymphoid Malignancies

Lymphoma | Hodgkin Lymphoma | Lymphoid Malignancies | Non-hodgkin Lymphoma

United States
University Health Network, Toronto

Completed

Safety Study Looking at the Use of a Natural Killer Cell Line Against Hematological Malignancies

Lymphoma | Leukemia | Myeloma | Hodgkin's Disease

Canada
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Hematologic Malignancies | Myeloid Metaplasia

United States
University of Chicago

Terminated

Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies

Lymphoma | Preleukemia | Myeloproliferative Disorders | Myeloma | Graft Versus Host Disease

United States
Lumicell, Inc.

Recruiting

Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies

Peritoneal Metastases

United States
Hospital Israelita Albert Einstein

Recruiting

Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies

Graft Versus Host Disease | Infection Viral | Bone Marrow Transplant Complications | Engraft Failure | Immunologic Suppression

Brazil
University of Michigan Rogel Cancer Center

Completed

Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies

Hematologic Malignancies | Graft-Versus-Host Disease | Relapse

United States
Amsterdam UMC, location VUmc
ZonMw: The Netherlands Organisation for Health Research and Development; Fo...

Completed

Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO (SHORT)

Febrile Neutropenia | Hematological Malignancy

Netherlands
Masonic Cancer Center, University of Minnesota

Terminated

Stem Cell Transplantation for Hematological Malignancies

AML | MDS | Leukemia, Lymphocytic, Acute

United States
University Hospital, Brest

Completed

Early Antibiotic Discontinuation in FUO (ANTIBIOSTOP)

Febrile Neutropenia | Hematological Malignancy

France
Seagen Inc.

Completed

Phase I Open-Label Dose Finding Study of SGN-35 for CD30 Positive Hematologic Malignancies

Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin

United States
Humanigen, Inc.

Suspended

Study of KB004 in Subjects With Hematologic Malignancies (Myelodysplastic Syndrome, MDS, Myelofibrosis, MF)

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF)

United States, Australia
Kymera Therapeutics, Inc.

Recruiting

Safety and Clinical Activity of KT-253 in Adult Patients With High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Advanced Solid Tumors | Acute Lymphocytic Leukemia | Lymphomas | Myeloid Malignancies

United States
He Huang
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

A Study of CTA30X Cell Injection in Patients With Relapsed or Refractory CD19-positive B-line Hematological Malignancies

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
He Huang
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

A Study of CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Aalborg University Hospital
Aalborg University

Active, not recruiting

Early Detection of Neuropathy and Cognitive Impairment Following Treatment for Haematological Malignancies (NOVIT1)

Chemotherapy-induced Peripheral Neuropathy

Denmark
Innovative Cellular Therapeutics Co., Ltd.

Unknown

Chimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B Cell Hematologic Malignancies

Lymphoma, B-Cell | Leukemia, B-Cell

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic Leukemia

Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies

United States
Huazhong University of Science and Technology
Shanghai IASO Biotechnology Co., Ltd

Not yet recruiting

Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies

Chronic Lymphocytic Leukemia (CLL) | Peripheral T-cell Lymphomas (PTCL) | CD5+ Relapsed/Refractory Hematopoietic Malignancies | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL)
Hospices Civils de Lyon

Unknown

French National Registry of Rare Peritoneal Surface Malignancies (RENAPE)

Pseudomyxoma Peritonei | Peritoneal Mesothelioma | Desmoplastic Small Round Cell Tumor | Rare Peritoneal Surface Malignancies | Psammocarcinoma | Primary Peritoneal Serous Carcinoma | Diffuse Peritoneal Leiomyomatosis | Appendiceal Mucinous Neoplasms

France
University Hospital, Montpellier

Recruiting

Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies (CAR-T BANK)

Lymphoma and Acute Lymphoblastic Leukemia

France
Institut Paoli-Calmettes

Completed

Unicentric Retrospective Analysis of a Cohort of 602 Young Adult and Adolescent Patients (AJA), Aged 15 to 30 Years, With Haematological Malignancies, and Managed Between 2000 and 2016 (HEMAJA)

Hodgkin Lymphoma | Acute Leukemia | Non-hodgkin Lymphoma | Malignant Haemopathies

France
University of Utah

Completed

Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies

Lymphoma | Leukemia | Chronic Disease | Myelodysplasia | Acute Leukaemia

United States
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relmacabtagene Autoleucel in Hematologic Malignancies

Lymphoma, B-Cell | Follicular Lymphoma | Large B-cell Lymphoma

China
University of Erlangen-Nürnberg Medical School

Unknown

WB-EMS and Nutrition in Patients With Hematological Malignancies

Lymphoma | Hematologic Diseases | Leukemia | Cancer | Myeloma | Cachexia; Cancer

Germany
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Wyeth is now a wholly owned subsidiary of Pfizer
PETHEMA (Program for the Study and Treatment of Haematological Malignances)

Completed

Study Comparing Piperacillin-tazobactam Versus Piperacillin-tazobactam Plus Glycopeptide in Neutropenic Patients

Lymphoma | Leukemia | Stem Cell Transplantation | Myelodysplasia | Myeloma | Hematological Malignancy

Spain
St. Jude Children's Research Hospital

Not yet recruiting

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

Lymphoma | Hematologic Malignancy | MDS | AML, Childhood | ALL, Childhood

United States
M.D. Anderson Cancer Center
Loxo Oncology

Recruiting

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

Mantle Cell Lymphoma | Non Hodgkin Lymphoma | Hematologic Malignancy

United States
First Affiliated Hospital of Zhejiang University

Recruiting

The Association of Microbiota Composition With cGVHD After Allo-HSCT

Complication | Hematologic Malignancy | Hematopoietic Stem Cell Transplantation | Chronic Graft-versus-host-disease

China
Xinqiao Hospital of Chongqing
The First Affiliated Hospital of Anhui Medical University; Nanfang Hospital... and other collaborators

Recruiting

Anti-CD7 U-CAR-T Cell Therapy for T/NK Cell Hematologic Malignancies

T-cell Lymphoma | T-cell Leukemia

China
Merck Sharp & Dohme LLC

Recruiting

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Hodgkin Disease

United States, Australia, Canada, Germany, Israel, Italy

Clinical Trials on Nonhematologic Malignancies

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