Clinical Trials on Normal Pancreatic Exocrine Function

Total 3298 results

Foundation for Liver Research

Withdrawn

Pancreatic Enzyme Suppletion in Pancreatic Cancer (EPC)

Adenocarcinoma of the Pancreas | Normal Pancreatic Exocrine Function

Netherlands
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Martin Angst

Completed

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

Normal Immune Cell Function

United States
Englewood Hospital and Medical Center

Withdrawn

Neuropsychological Testing Using Mobile Devices

Inpatients With Normal Neurological Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Subjects With Liver Function Injury | Normal Liver Function Subject

China
Instituto Ecuatoriano de Enfermedades Digestivas

Completed

Quantitative And Qualitative Eus Elastography

Normal Pancreatic Tissue

Ecuador
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Sanofi

Completed

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Germany
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Sanofi

Completed

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Hepatic Function Abnormal

Bulgaria, France
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
Sanofi

Terminated

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

Korea, Republic of, Germany
Geisinger Clinic

Completed

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

Abnormal Liver Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Synchrotron Imaging of Human Ovaries Ex Situ

Abnormal Female Reproductive Function

Canada
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Columbia University

Withdrawn

Comparison of Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) to Endoscopic Pancreatic Function Test (ePFT) in Diagnosing Pancreatic Exocrine Insufficiency

Pancreatic Cancer
AbbVie

Terminated

A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency (EPI)

United States
Hospital Clinico Universitario de Santiago

Recruiting

Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic Cancer (DEPARA)

Pancreatic Exocrine Insufficiency | Pancreatic Neoplasm Malignant Head Primary

Spain
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Hospital Ortopedico de Passo Fundo

Completed

Thoracic And Lumbar Burst Fracture: Correlation Between Structural Changes And Clinical Outcome Of Treatment

Traumatic Burst Fractures of the Thoracic or Lumbar Spine. | Normal Neurological Function

Brazil
RWTH Aachen University

Unknown

Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome (Pupillometry)

Cerebral Aneurysm | Pupillary Function, Abnormal

Germany
Massimo Falconi

Active, not recruiting

Patient Reported Outcomes Measures to Predict Pancreatic Surgery Outcomes (PRO-PANC1)

Quality of Life | Pancreatic Cancer | Nutritional Status | Patient Reported Outcome Measures | Pancreatectomy | Recovery of Function

Italy
Centre Leon Berard

Recruiting

PATAKESS Protocol : Clinical and Biological Analysis of Exocrine Pancreatic Tumors (PATAKESS)

Exocrine Pancreatic Cancer

France
University of Oklahoma

Recruiting

High Dose Omeprazole in Patients With Pancreatic Cancer (OU202005AJ)

Exocrine Pancreatic Cancer

United States
Changhai Hospital
Peking Union Medical College Hospital; Xuanwu Hospital, Beijing

Completed

PE-1 in the Diagnosis of Pancreatic Exocrine Insufficiency

Pancreatic Exocrine Insufficiency

China
Centre Francois Baclesse

Terminated

Oral Therapies in Oncology: Cognitive Function and Compliance

Cancer | Cognitive Function | Compliance | Oral Therapies

France
TORL Biotherapeutics, LLC
Translational Research in Oncology

Recruiting

First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer

Gastric Cancer | Advanced Solid Tumor | Pancreas Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States
TORL Biotherapeutics, LLC
Translational Research in Oncology

Recruiting

First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer

Gastric Cancer | Advanced Solid Tumor | Pancreas Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States
Massimo Raimondo, M.D.
Digestive Care, Inc.

Terminated

PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Insufficiency | Pancreatic Enzyme Abnormality

United States
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); Office of Dietary Supplements...

Completed

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP)

Second Hand Smoke | Pulmonary Function; Newborn, Abnormal | Infant Wheeze | In-utero Nicotine

United States
Medical University of South Carolina

Completed

LYmphangiogenesis FacTors in Heart Failure States (LYFT-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

United States
Solvay Pharmaceuticals

Terminated

Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Czech Republic, Denmark, Hungary, Latvia, Poland, Russian Federation, Sweden
Seoul National University Hospital

Unknown

Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems

Overweight | Abnormal Liver Function Tests

Korea, Republic of
Abbott

Completed

A Open-label Study to Assess the Safety of Oral Long-term Use of SA-001 in Pancreatic Exocrine Insufficiency

Pancreatic Exocrine Insufficiency, Chronic Pancreatitis, Pancreatectomy

Japan
Pharmacyclics LLC.

Completed

Study of Safety and Tolerability of PCI-27483 in Patients With Pancreatic Cancer Patients Receiving Treatment With Gemcitabine

Pancreatic Cancer | Exocrine Pancreatic Cancer | Ductal Adrenocarcinoma

United States
Ruijin Hospital

Recruiting

The Effect of PERT on Patients Undergoing Pancreaticoduodenectomy

Pancreatic Exocrine Insufficiency | Pancreaticoduodenectomy | Pancreatic Enzyme Replacement Therapy

China
Abbott Products
Datamap

Completed

Creon 40,000 for Treatment of PEI (Pancreatic Exocrine Insufficiency) Due to Chronic Pancreatitis

Pancreatic Insufficiency

India
University of Missouri-Columbia

Withdrawn

Distal Pancreatectomy With Partial Splenectomy for Pancreatic Tumors

Tumor of Exocrine Pancreas

United States
Azienda Ospedaliera Universitaria Integrata Verona

Recruiting

Pancreatic Cancer and Oral Microbiome

Pancreatic Cancer | IPMN | Oral Microbiome | Parodontopathy

Italy
Ohio State University
AbbVie

Active, not recruiting

Post Acute Pancreatitis Pancreatic Exocrine Insufficiency (PAPPEI)

Acute Pancreatitis

United States
Moscow Clinical Scientific Center
IRCCS San Raffaele; Istanbul University; University of Belgrade; University of... and other collaborators

Unknown

Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer (PAC-MAIN)

Pancreatic Cancer | Malnutrition | Chemotherapy | Exocrine Pancreatic Insufficiency | Metastatic Pancreatic Cancer | Locally Advanced Malignant Neoplasm

Turkey, Italy, Romania, Russian Federation, Serbia, Spain
University of Colorado, Denver

Recruiting

Contraceptive Hormone and Reward Measurement (CHARM Study) (CHARM)

Mood | Oral Hormonal Contraceptive Use | Neural Activity | Hedonic Function

United States
Orlando Health, Inc.
ChiRhoClin, Inc.

Terminated

Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency

Irritable Bowel Syndrome | Abdominal Pain

United States

Clinical Trials on Normal Pancreatic Exocrine Function

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations