Clinical Trials on Ocular Diseases

Total 379396 results

Envisia Therapeutics

Completed

Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma

Glaucoma and Ocular Hypertension

United States
Medical University of Vienna

Completed

The Effect of an α2-Adrenoceptor Antagonist (Yohimbine) on Dynamic Autoregulation in the Human Middle Cerebral Artery and Ophthalmic Artery

Ocular Physiology | Autoregulation | Blood Flow Velocity

Austria
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
Novartis Pharmaceuticals

Completed

An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases. (ECLIPSE)

Diabetic Retinopathy | Macular Edema | Choroidal Neovascularization | Glaucoma, Neovascular

France
Santen Pharmaceutical Co., Ltd.

Completed

A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma, Ocular Hypertension

China
Santen Inc.

Completed

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Open-angle Glaucoma, Ocular Hypertension

United States, Japan
Mahidol University

Completed

Efficacy of Cultivated Corneal Epithelial Stem Cell for Ocular Surface Reconstruction

Limbal Deficiency | Severe Ocular Surface Damage

Thailand
Medical University of Vienna

Completed

Is There a Difference in Flicker Induced Vasodilatation Between Smokers and Non-Smokers?

Ocular Physiology | Retina | Blood Flow Velocity

Austria
Centre hospitalier de l'Université de Montréal...

Recruiting

Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo) (KPro-HP-Endo)

Postoperative Complications | Endoscopy | Vitrectomy | Corneal Transplantation | Glaucoma and Ocular Hypertension

Canada
Novartis Pharmaceuticals

Completed

Study of SAF312 as an Eye Drop for Treatment of Eye Pain Following Photorefractive Keratectomy (PRK) Surgery

Postoperative Ocular Pain After PRK Surgery

United States
Ocular Therapeutix, Inc.

Completed

OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery

Post-Surgical Ocular Pain | Post-Surgical Ocular Inflammation
Ocular Therapeutix, Inc.

Completed

OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery

Post-Surgical Ocular Pain | Post-Surgical Ocular Inflammation
Otsuka Beijing Research Institute

Recruiting

OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

Open Angle Glaucoma or Ocular Hypertension

China
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
National Eye Institute (NEI)

Completed

Differences in Genes and Proteins in Active and Controlled Uveitis

Uveitis | Ocular Inflammatory Disease

United States
National Eye Institute (NEI)

Completed

Potential Research Participants for Future Studies of Inherited Eye Diseases

Glaucoma | Macular Degeneration | Retinitis Pigmentosa | Cataract | Strabismus

United States
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis (ISROT)

Ocular Toxoplasmosis

Brazil
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Qlaris Bio, Inc.

Recruiting

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Glaucoma | Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)

United States
University of California, San Diego
Bausch & Lomb Incorporated

Completed

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension

United States
University of California, San Diego
Aerie Pharmaceuticals

Withdrawn

Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma, Ocular Hypertension

Japan
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Vanderbilt University Medical Center

Completed

Can COVID-19 Persist in Intraocular Fluid?

Ocular Infection, Viral

United States
Kocaeli University

Unknown

Comparison of Intra Ocular Pressure After Insertion of the LMA Supreme and LMA Proseal in Pediatric Patients

Intra Ocular Pressure

Turkey
Allergan

Completed

A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin

Ocular Hypertension

United States
Johnson & Johnson Vision Care, Inc.

Completed

Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock

Ocular Physiology

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University
Affiliated Foshan Maternity & Child Healthcare Hospital, Southern Medical...

Not yet recruiting

Pediatric Eye Care Investigated Team (PECT)

Eye Diseases | Children | Ocular Surface Disease | Systemic Disease
Mayo Clinic

Terminated

Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear

Ocular Hypertension

United States
University of Houston

Completed

The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width

Ocular Hypertension

United States
Sensimed AG
Yale University

Terminated

IOP Patterns in Ocular Hypertensive Patients Newly Converted to Glaucoma vs Stable Ocular Hypertensive Patients

Ocular Hypertension

United States
Intuor Technologies, Inc.

Completed

Clinical Evaluation of CATS Tonometer Prism

Ocular Hypertension

United States
United States Naval Medical Center, San Diego

Completed

Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning

Ocular Hypertension

United States
Optovue

Completed

Comparison of OCT and OCTA-based Ocular Measurements to Those of Predicate

Normal Eyes and Eyes With Ocular Pathologies

United States
Medical University of Vienna

Completed

Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects

Intraocular Pressure | Ocular Physiology | Regional Blood Flow

Austria
Fondation Ophtalmologique Adolphe de Rothschild
Ministry of Health, France

Completed

Centralised Anesthesic Monitoring in the Surgery of the Ocular Anterior Segment: Non Inferiority Study (SACHS)

Ambulatory Surgical Procedures | Ocular Anterior Segment Surgery

France
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
McMaster University

Withdrawn

Prophylaxis for Anti-VEGF-induced IOP Elevation

Ocular Hypertension
Visualiza
Seva Foundation

Not yet recruiting

Safety and Effectiveness of Drop-free Small Incision Cataract Surgery

Ocular Hypertension | Ocular Inflammation | Cataract | Post-Op Complication
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD

Ocular Inflammation | Ocular Pain | Corneal Endothelial Cell Loss | Cataract Surgery

United States
Daniel Moore
Pfizer

Terminated

Safety Study of Latanoprost Slow Release Insert (Latanoprost SR)

Primary Open Angle Glaucoma (POAG) | Ocular Hypertension (OHT)

United States
University of California, San Francisco

Recruiting

Antibiotic Resistance In Eye Surgeries (ARIES)

Antibiotic Resistance | Ocular Surface Microbiome | Gut Resistome

United States
Topcon Medical Systems, Inc.

Withdrawn

Non-Invasive Imaging of the Human Eye

Willing and Able Subjects for Ocular Imaging

United States
Medical University of Vienna

Withdrawn

Role of Endothelin- and Nitric Oxide-system in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure

Ocular Physiology | Regional Blood Flow | Optic Disk

Austria
Medical University of Vienna

Completed

Role of Nitrogen Oxide (NO) in the Control of Choroidal Blood Flow During a Decrease in Ocular Perfusion Pressure

Regional Blood Flow | Microcirculation | Physiology, Ocular | Autoregulation

Austria
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States

Clinical Trials on Ocular Diseases

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CROs by country

CROs in Latvia

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Drug Interventions

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