Clinical Trials on Older Adult

Total 4156 results

National Cheng-Kung University Hospital

Completed

Biomechanical Characteristics of Lower Extremity During Pinnacle Trainer With Different Pedal Angles

Healthy Adult

Taiwan
University Hospital Inselspital, Berne

Terminated

HDM201 and Midostaurin (HDMM) in Relapsed/Refractory AML With FLT3mut and TP53wt. (HDMM)

AML, Adult

Switzerland
Baskent University

Completed

Tai Chi Exercise on Balance and Awereeness

Young Adult

Turkey
Centre Hospitalier Universitaire de Nīmes

Completed

Effect of the Physiological Angular Position of the Resting Knee on Pressure at the Heel/Surface Interface (FlessCare)

Adult, Hospitalized

France
Yonsei University

Completed

Investigatory Study of Metformin's Pharmacokinetics, Pharmacodynamics and Drug Drug Interactions Classifying the Group by MATE1 Genotype in Healthy Volunteers

Healthy Adult

Korea, Republic of
Great Lakes Research Into Practice Network
Robert Wood Johnson Foundation

Completed

Evaluation of Organisational Changes to Promote Smoking Cessation (ESCMMP)

Adult Smokers

United States
National Institutes of Health Clinical Center (CC)

Completed

Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IVA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma | Stage IVB Adult Soft Tissue Sarcoma
Beth Christian

Completed

Gemcitabine and Bendamustine in Patients With Relapsed or Refractory Hodgkin's Lymphoma

Recurrent Adult Hodgkin Lymphoma | Adult Lymphocyte Depletion Hodgkin Lymphoma | Adult Lymphocyte Predominant Hodgkin Lymphoma | Adult Mixed Cellularity Hodgkin Lymphoma | Adult Nodular Sclerosis Hodgkin Lymphoma | Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma

United States
Ohio State University Comprehensive Cancer Center

Completed

Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy

Adult Brain Tumor

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Symptom-Adapted Physical Activity Intervention in Minimizing Physical Function Decline in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Stanford University
National Cancer Institute (NCI)

Terminated

Lenalidomide and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Bruno C. Medeiros
National Cancer Institute (NCI)

Terminated

MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
BioNova Pharmaceuticals (Shanghai) LTD.

Recruiting

A Study of BN104 in the Treatment of Acute Leukemia

AML, Adult | ALL, Adult

China
Ege University

Completed

Evaluation of Sarcopenia With SARC-F and Anthropometric Measurement

Sarcopenia | Older People

Turkey
National Cancer Institute (NCI)

Terminated

18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Completed

AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Case Comprehensive Cancer Center

Completed

Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic Leukemia and other conditions

Canada
Enloe Health
Robert A. Winn Diversity in Clinical Trials Award Program

Not yet recruiting

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention (GENESIS)

Solid Tumor, Adult
New York Stem Cell Foundation Research Institute
Stevens Institute of Technology

Recruiting

Personalized Models for Cancer Research

Solid Tumor, Adult

United States
Jemincare

Not yet recruiting

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Solid Tumor, Adult
Portal Therapeutics, Inc.

Not yet recruiting

Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants

Healthy Adult Participants

United States
Hamad Medical Corporation

Recruiting

Effects of Early Oral Diet After Cardiac Surgery: an Open Label Randomized Controlled Trial

Adult Cardiac Surgery

Qatar
Visirna Therapeutics HK Limited
Arrowhead Pharmaceuticals

Not yet recruiting

Study of VSA001 Injection in Chinese Healthy Adult Volunteers

Healthy Adult Volunteers

China
China Resources Biopharmaceutical Co., Ltd
Peking University Third Hospital

Recruiting

A Trial of CRB4101 in Healthy Subjects

Healthy Adult Subjects

China
CatalYm GmbH

Recruiting

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER) (GDFATHER)

Solid Tumor, Adult

Spain, Germany, Switzerland
Ottawa Hospital Research Institute

Not yet recruiting

Motion Capture as a Tool for the Assessment of Laparoscopic Performance

Healthy | Adult ALL
University of Alabama at Birmingham

Recruiting

Non-Encapsulated Heme Levels in Adult Cardiac Surgery

Adult Cardiac Surgery

United States
Auzone Biological Technology Pty Ltd

Completed

Bioequivalence of TTYP01 Tablets in Healthy Adult Subjects

Healthy Adult Subjects

United States
National Cancer Institute (NCI)

Active, not recruiting

Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Adult Solid Neoplasm

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric Tube

Healthy Adult Subjects

Japan
iTeos Therapeutics
Merck Sharp & Dohme LLC

Active, not recruiting

First-in-Human Study of EOS100850 in Patients With Cancer

Solid Tumor, Adult

Spain, United States, France, Korea, Republic of, Belgium, United Kingdom
ImmuneSensor Therapeutics Inc.

Active, not recruiting

A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial

Solid Tumor, Adult

United States
Alvotech Swiss AG
Iqvia Pty Ltd

Completed

A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants

Healthy Adult Subjects

New Zealand, United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Bioavailability Study of SHR1459 on Healthy Chinese Volunteers

Healthy Adult Subjects

China
Connect Biopharma Australia Pty Ltd

Completed

Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults

Healthy Adult Subjects

Australia
University of Maryland, Baltimore
Vapotherm, Inc.

Completed

Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®)

Healthy Adult Volunteers

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase I, Open-Label Trial to Assess the Absorption, Metabolism, and Excretion of (14C)-OPC-61815 in Healthy Male Japanese Subjects

Healthy Adult Male

United Kingdom
Yonsei University

Completed

K-BASKET, TAS-117, PI3K/AKT Gene Aberration

Solid Tumor, Adult

Korea, Republic of
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Itraconazole Effect Study of SHR2554 on Healthy Chinese Adult Subjects

Healthy Adult Subjects

China
Nobelpharma

Completed

A Study of NPC-22 in Healthy Adult Males

Healthy Adult Subjects

Japan
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Food Effect Study of SHR1459 on Healthy Chinese Adult Subjects

Healthy Adult Subjects

China
Vivozon, Inc.

Completed

Absorption, Metabolism, Excretion, and Mass Balance Study of [14C]-VVZ-149 in Healthy Adult Male Subjects

Healthy Adult Male

United States
Henlix, Inc

Unknown

Evaluate Safety, Tolerability and PK of HLX55 in Patients With Advanced Solid Tumors With Different cMET Status

Solid Tumor, Adult

Taiwan
Jiangsu vcare pharmaceutical technology co., LTD

Completed

The Mass Balance and Biotransformation of [14C] Vicagrel in Healthy Man

Healthy Male Adult

China
Advanced Accelerator Applications
Atreus Pharmaceuticals Corporation

Completed

99mTc-rhAnnexin V-128: a First In Man Study in Healthy Volunteers

Healthy Adult Volunteers

Canada
University of Arizona

Completed

4-methylpyrazole and Acetaminophen Metabolism

Healthy Adult Volunteers

United States
Kyunghee University Medical Center

Completed

A Phase I Study of SH003 for Evaluate Safe Dose Range in Patients With Solid Cancer

Solid Tumor, Adult

Korea, Republic of
Takeda

Completed

A Bioequivalence Study of the Lu AA21004 20 mg and 2×10 mg Tablets

Healthy Adult Participants

Japan
Institut Paoli-Calmettes

Unknown

Feasibility of a Process of Digital Validation of Chemotherapies in a Day Treatment Unit (CPV2-0)

Solid Tumor, Adult

Clinical Trials on Older Adult

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