Clinical Trials on Open Angle Glaucoma and Ocular Hypertension

Total 1946 results

Alcon Research

Completed

Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma | Oular Hypertension

United States
Wills Eye

Completed

Comparison of Gonioscopy With Cirrus and Visante (ASOCT)

Open Angle Glaucoma | Angle Closure Glaucoma | Narrow Angles

United States
Santen Pharmaceutical Co., Ltd.

Recruiting

A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma, Ocular Hypertension

Japan
Sanofi

Completed

28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma -Ocular Hypertension

United States
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
Allergan

Completed

A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

Glaucoma | Open-Angle Ocular Hypertension

Spain, United States, Singapore, Australia, Denmark, France, Poland, Russian Federation, Thailand
Alcon Research

Completed

AL-54478 Proof of Concept Study

Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)
Qlaris Bio, Inc.

Recruiting

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Glaucoma | Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)

United States
University of California, San Diego
Bausch & Lomb Incorporated

Completed

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension

United States
University of California, San Diego
Aerie Pharmaceuticals

Withdrawn

Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension
Otsuka Beijing Research Institute

Recruiting

OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

Open Angle Glaucoma or Ocular Hypertension

China
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
United States Air Force
Alcon Research

Completed

Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative

Ocular Hypertension | Open-Angle Glaucoma | Ocular Dryness | Ocular Irritation

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma, Ocular Hypertension

China
Santen Inc.

Completed

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Open-angle Glaucoma, Ocular Hypertension

United States, Japan
Qlaris Bio, Inc.

Recruiting

Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT Patients

Primary Open Angle Glaucoma of Both Eyes | Primary Open Angle Glaucoma (POAG) | Primary Open-Angle Glaucoma, Unspecified Eye | Ocular Hypertension (OHT)

United States
Santen SAS

Completed

A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Surface Disease | Open-Angle Glaucoma or Ocular Hypertension

France
Santen Pharmaceutical Co., Ltd.

Completed

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma, Ocular Hypertension

Japan
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Daniel Moore
Pfizer

Terminated

Safety Study of Latanoprost Slow Release Insert (Latanoprost SR)

Primary Open Angle Glaucoma (POAG) | Ocular Hypertension (OHT)

United States
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Santen Pharmaceutical (Taiwan) Co., LTD

Completed

Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting

Primary Open Angle Glaucoma | Ocular Surface Disease

Taiwan
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
American Society Of Thermalism And Climatology Inc

Unknown

Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. (GME)

Primary Open Angle Glaucoma | Hypertension Ocular

United States
Allergan

Recruiting

18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA) (ARGOS)

Ocular Hypertension | Open-angle Glaucoma

United States
Asociación para Evitar la Ceguera en México

Terminated

PASCAL Trabeculoplasty

Open-Angle Glaucoma

Mexico
Aerie Pharmaceuticals

Completed

A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months

Ocular Hypertension | Open-angle Glaucoma
West Virginia University
University of Pittsburgh; University of Michigan

Withdrawn

African Glaucoma Laser Trial (AGLT)

Open-angle Glaucoma
Glaukos Corporation

Unknown

A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2

Open-Angle Glaucoma

Spain, Germany, Austria, Turkey
Alcon Research

Completed

24 Hour IOP Lowering Efficacy of AL-3789

Open-angle Glaucoma

United States
Alcon Research

Withdrawn

A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Open-Angle Glaucoma
Pharmaceutical Research Network

Completed

Lumigan Versus Cosopt

Open-Angle Glaucoma

United States
Pharmaceutical Research Network

Completed

Cosopt Versus Xalatan

Ocular Hypertension | Open-Angle Glaucoma

United States
National Eye Institute (NEI)

Completed

Glaucoma Laser Trial (GLT) Glaucoma Laser Trial Followup Study (GLTFS)

Open-Angle Glaucoma
National Eye Institute (NEI)

Unknown

Collaborative Initial Glaucoma Treatment Study (CIGTS)

Open-Angle Glaucoma
OcuTherix, Inc.

Terminated

Safety and Efficacy of Deep Wave Trabeculoplasty (DWT) in Primary Open Angle Glaucoma and Ocular Hypertension

Primary Open-angle Glaucoma (POAG) | Ocular Hypertension (OHT)

Philippines
Inotek Pharmaceuticals Corporation

Completed

Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma (MATrX-1)

Ocular Hypertension (OHT) | Primary Open-Angle Glaucoma (POAG)

United States
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Ono Pharma USA Inc

Completed

Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma

Ocular Hypertension (OHT) | Mild Open Angle-glaucoma (OAG)

United States
Columbia University

Recruiting

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

Primary Open Angle Glaucoma

United States
Hospital Clinic of Barcelona

Completed

Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery Outcomes (IIT_XEN)

Glaucoma | Glaucoma Open-Angle Primary

Spain
Transcend Medical, Inc.

Completed

Safety and Performance Study of the CyPass System Applier Model 241 (RePASS)

Open Angle Glaucoma (OAG)

Germany
Federico II University

Completed

OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

Glaucoma Open-Angle Primary

Italy
AbbVie

Active, not recruiting

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States, Argentina, Australia, Bulgaria, Czechia, Denmark, Germany, Hungary, Ireland, Italy, New Zealand, Poland, Russian Federation, South Africa, Sweden, United Kingdom
AbbVie

Completed

A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Allergan

Completed

Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China

Clinical Trials on Open Angle Glaucoma and Ocular Hypertension

Sponsors and Collaborators

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Drug Interventions

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