Clinical Trials on Opioids; Harmful Use in United Kingdom

Total 3960 results

Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
Columbia University
Boston University; National Institute on Drug Abuse (NIDA); Johns Hopkins University and other collaborators

Completed

Assessing Long-term CTN 0049 Outcomes, HCV Prevalence and Progression Along the HCV Care Continuum Among HIV/HCV Co-infected Substance Users in the U.S. (CTN 0064)

Hepatitis C | HIV | Substance Use | AIDS

United States
Duke University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); University at Buffalo

Recruiting

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings (MTQT)

Schizophrenia | Schizoaffective Disorder | Tobacco Use Disorder | Bipolar Disorder | Mental Illness | Persistent Depressive Disorder | Recurring Major Depressive Disorder

United States
University of Louisville

Withdrawn

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Pelvic Organ Prolapse | Surgery | Narcotic Use | Post Operative Pain Control | Urinary Incontinence , Stress

United States
Biotronik, Inc.
University of Rochester

Active, not recruiting

Analysis of Both Sex and Device Specific Factors on Outcomes in Patients With Non-Ischemic Cardiomyopathy (BIO-LIBRA)

Cardiomyopathies | Implantable Defibrillator User | Gender

United States
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
University of Pittsburgh
National Institute on Drug Abuse (NIDA); University of Alabama at Birmingham; National Institutes of Health (NIH) and other collaborators

Recruiting

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

Substance Use | Human Immunodeficiency Virus | Stigma, Social

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients

Breast Cancer | Colorectal Cancer | Tobacco Use Disorder | Lung Cancer | Prostate Cancer

United States
Liberating Technologies, Inc.
Hanger Clinic: Prosthetics & Orthotics

Recruiting

Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees

Lower Limb Amputation Above Knee (Injury) | Amputation | Prosthesis User | Amputation; Traumatic, Leg, Lower | Limb; Absence, Congenital, Lower | Amputation; Traumatic, Leg: Thigh, Between Hip and Knee

United States
G.V. (Sonny) Montgomery VA Medical Center
Merck Sharp & Dohme LLC

Completed

VBMI to Increase Treatment Completion With MK-MK-5172/MK-8742 Among Veterans With Active Substance Use Disorders Genotype 1 Chronic Hepatitis C (VBMI SUD/HCV)

Patient Adherence, Chronic Hepatitis C, Alcohol-related Disorders

United States
University of Pennsylvania
National Cancer Institute (NCI); Northwestern University

Recruiting

Optimizing Tobacco Use Treatment for PLWHA (HTO)

HIV/AIDS | Nicotine Dependence

United States
University of Oklahoma
Centers for Disease Control and Prevention

Completed

Development of Education Materials for Prevention of FAS in Russia

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome (FAS) | Alcohol Related Neurodevelopmental Disorder | Alcohol Use Complicating Pregnancy, Unspecified Trimester

United States, Russian Federation
Stanford University

Terminated

Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients

Sleep Apnea Syndromes | Opioid-Related Disorders | Morbid Obesity | Surgery--Complications

United States
Liberating Technologies, Inc.
Hanger Clinic: Prosthetics & Orthotics

Recruiting

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

Lower Limb Amputation Above Knee (Injury) | Amputation | Prosthesis User | Amputation; Traumatic, Leg, Lower | Limb; Absence, Congenital, Lower | Amputation; Traumatic, Leg: Thigh, Between Hip and Knee

United States
VA Office of Research and Development

Completed

Cardiovascular Risk Screening and Risk Reduction in Women Vets

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus | Overweight | Dyslipidemias | Tobacco Use Disorder | Hyperlipidemias

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Rutgers, The State University of New Jersey

Terminated

Use of Transesophageal Echocardiography to Measure Intraoperative Renal Resistive Index and Predict Acute Renal Injury

Subjects Undergoing Cardiac or Major Surgery Where TEE is Used as a Matter of Routine

United States
University of Houston
National Institute on Drug Abuse (NIDA)

Completed

Project PRIDE (Promoting Resilience In Discriminatory Environments)

Depression | Anxiety | Substance Use Disorders | Sexually Transmitted Infections | Human Immunodeficiency Virus

United States
RTI International
Durham County Department of Public Health; Guilford County Department of Public... and other collaborators

Terminated

NC Young Women's CoOp

Human Immunodeficiency Virus (HIV) | Condomless Sex | Alcohol and Drug Use | Sexually Transmitted Infection (STI)

United States
Northwestern University
University of Washington

Completed

Targeted Reinnervation for Neuromas as a Means to Improve Prosthesis Control in Major Limb Amputation

Pain | Prosthesis User | Neuroma | Prosthesis Failure

United States
University Medical Center Goettingen

Completed

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in Europe (EU-CERT-ICD)

Myocardial Infarction | Coronary Artery Disease | Dilated Cardiomyopathy | Implantable Defibrillator User

Hungary, Poland, Belgium, Bulgaria, Croatia, Czechia, Denmark, Finland, Germany, Greece, Netherlands, Slovakia, Spain, Sweden, Switzerland, United Kingdom
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking

Breast Cancer | Colorectal Cancer | Tobacco Use Disorder | Lung Cancer | Prostate Cancer

United States
Knight Therapeutics (USA) Inc

Recruiting

Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy Registry

Leishmaniasis or Other Uses of Miltefosine

United States
University of Maryland, Baltimore
Johns Hopkins University; Harvard School of Public Health (HSPH)

Recruiting

Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention

Infections | Inflammation | Overweight and Obesity | Respiratory Disease | Insufficient Sleep | Body Mass Index | Allergies | Congestion | Skin Conditions | Antibiotic Use | Digestive Disease

United States
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
Boston Children's Hospital

Recruiting

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Pain | Emergence Delirium | Anesthesia | Tonsillitis | Opioid Analgesic Adverse Reaction | Post-operative Nausea and Vomiting (PONV)

United States
Glyciome, LLC
Brigham and Women's Hospital; University of Puerto Rico

Completed

Perception & Acceptability of a Cervical Cancer Prevention Prebiotic Device

Sensory Perceptual Characteristics | User Acceptability of Gel Delivery System

United States, Puerto Rico
Stanford University

Completed

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness

Obesity | Schizophrenia | Metabolic Syndrome | Bipolar Disorder | Weight Gain | Ketogenic Dieting | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder

United States
VA Office of Research and Development

Active, not recruiting

Pilot rTMS for AUD+mTBI (TMS_AUD+mTBI)

Alcohol Use Disorder | Post-traumatic Stress Disorder | Mild Traumatic Brain Injury

United States
University of California, Los Angeles
California HIV/AIDS Research Program; Friends Research Institute, Inc.; Charles... and other collaborators

Completed

Prevention Support for People Leaving Jail (MEPS)

HIV Infections | Hepatitis C | Substance Use Disorders | Sexually Transmitted Diseases, Bacterial

United States
Indiana University
United States Department of Defense; University of Notre Dame

Completed

Limb Health and Socket Pressure in Response to Powered Ankle Protheses (OPORP)

Amputation | Prosthesis User | Mobility Limitation | Pressure Ulcer, Ankle | Prosthesis Durability | Skin Wound | Amputation; Traumatic, Foot | Limb Deficiencies

United States
University of Florida
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sleep and Ventricular Arrhythmias Study (SAVE)

Insomnia | Implantable Defibrillator User | Cardiac Arrhythmia

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
Yale University
National Institute on Drug Abuse (NIDA); Howard University; George Mason University

Completed

HIV, Buprenorphine, and the Criminal Justice System (STRIDE)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence

United States
Massachusetts General Hospital
Baylor College of Medicine; University of Houston; University of Texas at Austin and other collaborators

Recruiting

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

Depression | Smoking | Smoking Cessation | Anxiety | Nicotine Dependence | Human Immunodeficiency Virus | Smoking, Cigarette

United States
University of Texas Southwestern Medical Center

Completed

Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. (PSE)

Hepatic Encephalopathy | Cirrhosis | Portosystemic Encephalopathy | PSE

United States
Mayo Clinic

Enrolling by invitation

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

Autoimmune Diseases | Diabetes | Chronic Kidney Diseases | Tobacco Use | Overweight or Obesity | Inflammatory Disease | MRSA | Infections Joint Prosthetic | MSSA Colonization

United States
Yale University
National Institute on Drug Abuse (NIDA); Howard University; George Mason University

Completed

HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence

United States
Massachusetts General Hospital

Recruiting

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Schizophrenia | Bipolar Disorder | Traumatic Brain Injury | Attention Deficit Hyperactivity Disorder | Major Depressive Disorder | Borderline Personality Disorder | Substance Use Disorders

United States
Stanford University

Not yet recruiting

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness

Obesity | Metabolic Syndrome | Bipolar Disorder | Bipolar and Related Disorders | Bipolar Depression | Weight Gain | Bipolar I Disorder | Ketogenic Dieting | Bipolar Disorder I | Bipolar II Disorder | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder | Bipolar Disorder, Type... and other conditions

United States
University of California, Davis
University of California, Irvine

Completed

Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer (CLOVER)

Obesity | Hepatitis C | Lung Cancer | Pneumonia, Bacterial | Tobacco Use Cessation | Colon Cancer | Shingles

United States
Brigham and Women's Hospital
Northeastern University

Completed

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered (PSLL)

Venous Thromboembolism | Patient Fall | Adverse Drug Event | Severe Hypoglycemia | Hospital Acquired Pressure Ulcer | Central Line-Associated Bloodstream Infection (CLABSI) | Catheter-Associated Infection | Opioid-Related Severe Adverse Drug Event | Severe Hospital Acquired Delerium | Rapid Response Related...

United States
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
April M Young
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Sexually Transmitted Diseases | Opioid-Related Disorders | Substance Abuse | Drug Overdose | Opiate Substitution Treatment | Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV) | Intravenous Drug Usage

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer

Tobacco Use Disorder | Fanconi Anemia | Lichen Planus | Oral Neoplasm | Erythroplakia | Premalignant Lesion | Oral Cavity and Lip Precancerous Condition | Oral Cavity Leukoplakia

United States
National Institutes of Health Clinical Center (CC)
Harvard Medical School (HMS and HSDM); National Cancer Institute (NCI); National... and other collaborators

Completed

Hospital COVID-19 Surge and Associated Mortality Risk

Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer

Tobacco Use Disorder | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Limited Stage Small Cell Lung Cancer | Stage IA Non-small Cell Lung Cancer | Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB...

United States
University of Alabama at Birmingham
Johns Hopkins University

Recruiting

Study of Treatment for HPV16+ ASC-US or LSIL (PVX-6)

ASC-US | LSIL

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Butler Hospital
National Cancer Institute (NCI)

Completed

Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States

Clinical Trials on Opioids; Harmful Use in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Albania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations