Clinical Trials on Optic Disk Drusen

Total 3494 results

Ottawa Hospital Research Institute
University of Toronto; University of Western Ontario, Canada; University of Ottawa

Active, not recruiting

Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database

Sleep Apnea Syndromes | Restless Legs Syndrome | Opioid Use | Risk Factors | Prognosis | Periodic Limb Movement Sleep Disorder | Polysomnography | Sleep Arousal Disorders

Canada
Association for Innovation and Biomedical Research...

Completed

Prospective, Randomized, Open Label, Phase II Study to Assess Efficacy and Safety of Macugen® (Pegaptanib 0.3 mg Intravitreal Injections) Plus Panretinal Photocoagulation and PRP (Monotherapy) in the Treatment With High Risk PDR.

Diabetes Mellitus Type II | Diabetes Mellitus Type I | High Risk Proliferative Diabetic Retinopathy

Portugal
Promyco Diagnostics
Soroka University Medical Center

Unknown

Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy

Preterm Labor | High Risk Pregnancy | Genital Mycoplasma Infection

Israel
European Institute of Oncology

Recruiting

Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens

Anal Cancer | High-Risk Cancer | Anal Intraepithelial Neoplasia 2 | Anal Intraepithelial Neoplasia 1

Italy
Charite University, Berlin, Germany
Alnylam Pharmaceuticals

Not yet recruiting

Lumasiran in Hyperoxalaemic Patients on Haemodialysis (LHOxH)

Cardiovascular Disease | Cardiovascular Risk Factor | Haemodialysis | Chronic Kidney Disease Requiring Chronic Dialysis | Hyperoxalemia
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SHR-2005 Intravesical Instillation in the Treatment of High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

High-risk Non-muscle Invasive Bladder Cancer

China
Qing XIe

Recruiting

A Prospective Study to Evaluate Peginterferon in Reducing the Incidence of HCC in CHB Patients

Chronic Hepatitis B | Intermediate to High Risk of HCC

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

The Patient Cohort of the National Center for Precision Medicine in Leukemia (eTHEMA)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | High-risk Myelodysplastic Syndrome | Myeloproliferative Neoplasm, Unclassifiable | Secondary Myelofibrosis in Myeloproliferative Disease
University of Toronto
United Soybean Board

Active, not recruiting

The Soy Treatment Evaluation for Metabolic Health (STEM) Trial

Cardiovascular Diseases | Hypertension | Obesity | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemias | PreDiabetes | Overweight and Obesity | Dysglycemia | Healthy Obesity, Metabolically | Heart Disease Risk Factors

Canada
University of Alberta
Alberta Health services; Alberta Health & Wellness; Merck Frosst Canada Ltd.

Completed

The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH (RxEACH)

Diabetes | Chronic Kidney Disease | Established Atherosclerotic Vascular Disease | Framingham Risk Score More Than 20 Percent

Canada
University of Modena and Reggio Emilia

Unknown

Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic Complications

Exercise Addiction | Dietary Modification | High-Risk Pregnancy | Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled

Italy
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Completed

A Randomized Trial of Vaccine Adherence in Young Injection Drug Users (UFO VAX)

Substance Abuse, Intravenous | Risk Behavior | Hepatitis B | Hepatitis A | Hepatitis C | Medication Adherence

United States
Karyopharm Therapeutics Inc

Active, not recruiting

Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications

Acute Myeloid Leukemia (AML) | Metastatic Colorectal Cancer (mCRC) | Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Relapsed/Refractory Multiple Myeloma (RRMM) | Higher-Risk Myelodysplastic Syndrome (HR-MDS) | Newly Diagnosed Intermediate/High-Risk MDS

United States, France, Canada, Spain, China
3D Medicines

Active, not recruiting

Study of 3D189 in Patients With Hematologic Malignancies

Multiple Myeloma | Non-Hodgkin Lymphoma | Acute Leukemia | Higher-risk Myelodysplastic Syndrome

China
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Center for AIDS...

Completed

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP (PARTNERUP)

Hepatitis C | Hiv | Opioid Use Disorder | Opioid Use | Risk Reduction

United States
Bellicum Pharmaceuticals

Withdrawn

Study of Matched Unrelated Donor T Cell Infusion for Hematologic Malignancies After Allo-HSCT

Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Lymphomas | Other High-risk Hematological Malignancies
Fox Chase Cancer Center

Completed

Dose Dense MVAC for Muscle Invasive Bladder Cancer

Muscle Invasive Bladder Cancer | High Risk Urothelial Carcinoma of the Upper Urinary Tracts

United States
Prokarium Ltd

Recruiting

A Phase 1/1b Study of ZH9 Treatment in Patients With Non-Muscle Invasive Bladder Cancer (PARADIGM-1)

NMIBC | Non Muscle Invasive Bladder Cancer | High Risk NMIBC

United States
University of Aarhus
Aarhus University Hospital; Aalborg University Hospital; The University of Queensland

Recruiting

Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-MET)

Diabetes Mellitus, Type 2 | Insulin Resistance | Pregnancy, High Risk | Overweight and Obesity | Insulin Sensitivity | Gestational Diabetes | Pregnancy in Diabetic

Denmark
Asan Medical Center
Medtronic

Recruiting

Evaluation of Prevalence and Clinical Impact of Atrial Fibrillation in Elderly Patients With Cryptogenic Stroke and High-Risk Patent Foramen Ovale (DefenseElderly)

Cryptogenic Stroke | High Risk Patent Foramen Ovale

Korea, Republic of
Hospices Civils de Lyon

Recruiting

Pressure and Diabetic Foot (PIV & MPP)

Diabetes and Risk of Diabetic Foot Ulcer

France
Karolinska University Hospital
Umeå University

Enrolling by invitation

Pancreatic Cancer Initial Detection Via Liquid Biopsy (PANCAID)

Pancreatic Cancer | Chronic Pancreatitis | IPMN, Pancreatic | Individuals at Risk

Sweden
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

B-cell Childhood Acute Lymphoblastic Leukemia | L1 Childhood Acute Lymphoblastic Leukemia | L2 Childhood Acute Lymphoblastic Leukemia | Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia

United States, Canada, Australia, Switzerland
Radboud University Medical Center
Catharina Ziekenhuis Eindhoven

Active, not recruiting

STOP OVarian CAncer; Implementation of the Opportunistic Salpingectomy in the Netherlands (STOPOVCA)

Ovarian Cancer | Risk Reduction

Netherlands
University of British Columbia

Withdrawn

Trial of Local Cystoscopic Injection of Tremelimumab Plus Systemic Durvalumab for High Risk Non-Muscle Invasive Bladder Cancer (Rideau)

Bladder Cancer | High-Risk Cancer | Durvalumab | Non-muscle Invasive | Tremelimumab

Canada
Laboratoire De Recherche Sur Le Diabete, Université...
ATRSS, DGRST, Algeria

Unknown

Covid-19 and Diabetes in West of Algeria (COVIDIAB-13)

Severe Acute Respiratory Syndrome | Coronavirus Infections | Diabetes Mellitus | Prevalence | Risk Factors | Patient Outcome Assessment

Algeria
University Hospital, Clermont-Ferrand

Completed

Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients (PrediRAGE)

Intensive Care Unit | Population at High Risk for ARDS Development

France
Dr Cipto Mangunkusumo General Hospital

Unknown

The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR)

Dry Eye Syndromes | Non-Proliferative Diabetic Retinopathy | Proliferative Diabetic Retinopathy New Vessels on Disc
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Support for Women at Risk for Heart Disease

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus, Non-insulin Dependent | Coronary Heart Disease Risk Reduction
Miquel Angel Pavon Ribas
Catalan Institute of Health; Hospital del Mar

Recruiting

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III) | Human Papillomavirus (HPV) Infections | High-risk HPV | HPV-16/ 18

Spain
Odense University Hospital
Novo Nordisk A/S; Department of Nephrology, Odense University Hospital; The A... and other collaborators

Recruiting

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH)

Kidney Failure, Chronic | Kidney Injury | Risk Reduction | Contrast-induced Nephropathy

Denmark
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Aalborg University Hospital and other collaborators

Recruiting

Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders. (HI-MET)

Diabetes Mellitus, Type 2 | Insulin Resistance | Pregnancy, High Risk | Overweight and Obesity | Insulin Sensitivity | Gestational Diabetes | Pregnancy in Diabetic

Denmark
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

High-risk Non-muscle Invasive Bladder Cancer

Canada, Belgium, United States, Australia, Austria, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Norway, Peru, Poland, Portugal, Spain, Switzerland, Turkey, United Kingdom, China, Brazil, Co... and more
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Moritz Oberndorfer
Merck Gesellschaft mbH, Austria

Completed

Lipid Profile and Diabetes Mellitus in People With HIV

HIV Infections | Diabetes Mellitus | Dyslipidemias | Cardiovascular Risk Factor

Austria
Hospital Universitari Vall d'Hebron Research Institute

Completed

Predisection Risk Factors for Vocal Cord Palsy After Total Thyroid Surgery

Recurrent Laryngeal Nerve Palsy | Risk Factors of Vocal Cord Palsy | Neuromonitoring in Thyroid Surgery
National Cancer Institute (NCI)

Completed

Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Myelomonocytic Leukemia-2

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Refractory Neuroblastoma | High Risk Neuroblastoma | Resectable Osteosarcoma

United States, Canada
Maastricht University Medical Center

Active, not recruiting

Needs and Preferences of Patients With Head-neck Cutaneous SCC

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Patient Satisfaction | Decision Making | Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer | Preference, Patient | I...

Netherlands
Eurasian Association of Therapists

Completed

Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection (ACTIV-2)

Diabetes | Covid19 | Death | Atrial Fibrillation | Risk Factor, Cardiovascular | CKD | COPD | Comorbidities and Coexisting Conditions | DVT

Russian Federation
Turku University Hospital
University of Turku

Completed

Nutrition and Pregnancy Intervention Study

Liver Diseases | Obesity | Pregnancy | Neurodevelopmental Disorders | Type2 Diabetes | Adiposity | Cardiovascular Risk Factor | Gestational Diabetes Mellitus | Eating Behavior | Cognitive Developmental Disorders

Finland
Sellas Life Sciences Group

Unknown

WT1 Analog Peptide Vaccine in Patients With Multiple Myeloma Following Autologous Stem Cell Transplantation

Multiple Myeloma | Minimal Residual Disease | High-Risk Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome and other conditions

United States
Atara Biotherapeutics
Memorial Sloan Kettering Cancer Center

Completed

Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma

United States
Uskudar State Hospital

Not yet recruiting

Awareness of Osteoporosis in HIV Patients

Osteoporosis | Osteoporosis Risk | Human Immunodeficiency Virus Infection
Universidad Politecnica de Madrid
Puerta de Hierro University Hospital; Hospital Vall d'Hebron; Hospital Severo... and other collaborators

Recruiting

Active Pregnancy Against COVID-19 (ACPREGCOV)

Pregnancy Complications | Pregnancy, High Risk | Maternal-Fetal Relations | Fetal Growth Retardation | Newborn Morbidity | Weight Gain, Maternal | Pregnancy Induced Hypertension | Fetus Disorder

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blasts More Than 10 Percent of Bone Marrow Nucleated Cells

United States
Roswell Park Cancer Institute
Celldex Therapeutics

Completed

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Refractory Anemia | Blasts 30 Percent or Less of Bone Marrow Nucleated Cells

United States
Oslo University Hospital
University of Oslo; Rigshospitalet, Denmark; University of Oxford; Norwegian SIDS... and other collaborators

Enrolling by invitation

HOME: Home Monitoring of High-risk Pregnancies

Preeclampsia | High Risk Pregnancy | Hypertensive Disorder of Pregnancy | Premature Preterm Rupture of Membranes | Previous Adverse Obstetric Outcome

Norway
Columbia University
National Institute of Mental Health (NIMH); Yale University

Active, not recruiting

Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings

Depression, Anxiety | Human Immunodeficiency Virus | Risk Reduction | Alcohol Abuse | Behavior, Sex

Romania

Clinical Trials on Optic Disk Drusen

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