Clinical Trials on Optic Nerve Neoplasms in Ireland

Total 2634 results

Eli Lilly and Company

Completed

A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors

Nonarteritic Anterior Ischemic Optic Neuropathy

United States
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Cancer Trials Ireland
Royal College of Surgeons, Ireland

Terminated

Blood Biomarker Signature in Glioma

Glioma of Brain

Ireland
Cancer Trials Ireland

Completed

A Translational Systems Medicine Approach to Provide Predictive Capacity for Therapy Response in Advanced or Metastatic Malignant Melanoma (SYS-ACT)

Metastatic Melanoma | Advanced Melanoma

Ireland
Cork University Hospital

Completed

To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade

Bimalleolar Fractures of the Ankle. | Sciatic Nerve Block. | Saphenous Nerve Block. | Post Operative Analgesia Duration.

Ireland
Cancer Trials Ireland

Completed

Sulindac and Epirubicin in Treating Patients With Metastatic Malignant Melanoma

Melanoma (Skin)

Ireland
Iceland Genomics Corporation
National Cancer Institute (NCI)

Completed

Studying Genes to Identify Melanoma in Patients in Iceland and Their Family Members

Melanoma (Skin)

Iceland
King's College Hospital NHS Trust

Recruiting

The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)

Pheochromocytoma | Paraganglioma

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy Followed By Surgery With or Without Radiation Therapy in Treating Young Patients With Stage II or Stage III Neuroblastoma

Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Infants With Neuroblastoma

Neuroblastoma

United Kingdom, Ireland
Brown University

Unknown

Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma

Morton's Neuroma

United States
Sigma-Tau Research, Inc.
Rhode Island Hospital

Completed

This is an Early Study to Investigate the Effect of Gimatecan® in Adults With Malignant Glioma.

Malignant Glioma

United States
Children's Cancer and Leukaemia Group

Completed

Temozolomide in Treating Young Patients With High-Risk Relapsed or Refractory Neuroblastoma

Neuroblastoma

United Kingdom, Ireland, France
Brown University
Rhode Island Hospital; Merrimack Pharmaceuticals

Terminated

BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastoma (329)

Glioblastoma | Glioblastoma Multiforme | GBM

United States
The Adelaide and Meath Hospital, incorporating...

Completed

Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?

Phrenic Nerve Palsy

Ireland
University of Dublin, Trinity College
St. James's Hospital, Ireland; Irish Cancer Society; Tallaght University Hospital and other collaborators

Completed

Exercise Prescription in Patients With Bone Metastases (Ex-Met)

Bone Metastases | Advanced Cancer

Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Molecular Insight Pharmaceuticals, Inc.

Completed

Phase 1 Study of Iobenguane (MIBG) I 131 in Patients With Malignant Pheochromocytoma/Paraganglioma

Pheochromocytoma | Paraganglioma

United States
Cancer Trials Ireland
University College Cork

Active, not recruiting

Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer (Lithium)

Colorectal Neoplasms | Esophageal Neoplasms | Stomach Neoplasm

Ireland
Brown University
The Miriam Hospital; Rhode Island Hospital

Active, not recruiting

Adjuvant Nivolumab & Low Dose Ipilimumab for Stage III & Resected Stage IV Melanoma

Melanoma

United States
Children's Cancer and Leukaemia Group

Unknown

Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma

Brain and Central Nervous System Tumors

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Cancer Trials Ireland

Active, not recruiting

Spine SABR - Dose-escalated Stereotactic Ablative Body Radiotherapy (SABR) for Solid Tumour Spine Metastases (Spine-SABR)

Solid Tumor Spine Metastases

Ireland
Washington University School of Medicine
Boston's Children Hospital

Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Malignant Peripheral Nerve Sheath Tumors

United States, Canada, United Kingdom, India
Cancer Trials Ireland

Completed

Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Melanoma (Skin)

Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery

Brain and Central Nervous System Tumors

United Kingdom, Ireland
University of Birmingham
Roche Pharma AG; Cancer Research UK; Imagine for Margo; EUSA Pharma, Inc.

Active, not recruiting

Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children (BEACON)

Neuroblastoma

France, Austria, Belgium, Denmark, Ireland, Italy, Spain, Switzerland, United Kingdom, Netherlands
Mater Misericordiae University Hospital
Penn State University; Krankenhaus der Barmherzigen Bruder Graz; Institut de... and other collaborators

Not yet recruiting

CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery Study 1

Rectal Cancer | Rectum Neoplasm | Rectum Polyp

Ireland
Heinrich Elinzano, MD
University of Texas; Rhode Island Hospital; Progenics Pharmaceuticals, Inc.

Completed

BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme | Gliosarcoma | GBM

United States
University College Cork
Irish Cancer Society; Cancer Research@UCC

Recruiting

Linking In With Advice and Supports for Men Impacted by Metastatic Cancer (LIAM Mc)

Kidney Cancer | Prostate Cancer | Penile Cancer | Survivorship | Testicular Cancer | Urothelial Tract/Bladder Cancer, Nos

Ireland
Brown University
NovoCure Ltd.

Not yet recruiting

NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis

Metastatic Melanoma | Melanoma Brain Metastasis

United States
South Eastern Health and Social Care Trust

Unknown

Negative Pressure Wound Therapy in Groin Dissection

Neoplasm Metastasis | Skin Neoplasms | Secondary Malignant Neoplasm of Lymph Node | Non-healing Surgical Wound (Disorder)

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
University of Leicester

Unknown

Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma

Neuroblastoma

Ireland, United Kingdom, France, Switzerland, Austria, Italy, Spain, Norway, Belgium, Denmark, Israel, Portugal, Sweden
Children's Cancer and Leukaemia Group

Unknown

Chemotherapy With or Without Radiation Therapy or Observation in Treating Young Patients With Advanced Retinoblastoma Who Have Undergone Surgery to Remove the Eye

Retinoblastoma

United Kingdom
Cancer Trials Ireland

Completed

PAD. ICORG 05-01, V11

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom, Ireland
Cancer Trials Ireland

Terminated

Pre-operative 3-DCRT vs IMRT for Locally Advanced Rectal Cancer (TRI-LARC)

Locally Advanced Rectal Cancer

Ireland
Children's Cancer and Leukaemia Group

Unknown

Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Mercy University Hospital, Cork, Ireland
The Adelaide and Meath Hospital; St. James Hospital, Dublin

Completed

Endoscopic Treatment of Inoperable Colorectal Cancer With the EndoVe System (CCEE EndoVe)

Colorectal Cancer

Ireland
St Vincent's University Hospital, Ireland

Completed

A Review of Functional and Surgical Outcomes of Gynaecological Reconstruction in the Context of Pelvic Exenteration

Pelvic Cancer

Ireland
St Vincent's University Hospital, Ireland

Recruiting

A Contemporary Review of Surgical Approaches in Pelvic Exenterative Surgery

Locally Advanced Rectal Cancer | Pelvic Exenteration | Advanced Pelvic Malignancy

Ireland
St. Joseph's Hospital and Medical Center, Phoenix

Unknown

Multi-site Validation and Application of a Consensus DSC-MRI Protocol

Glioblastoma Multiforme | Gliosarcoma

United States
St. James's Hospital, Ireland

Completed

The Predictive Value of CT-PET in Esophageal Cancer

Esophageal Neoplasms

Ireland
University of Dublin, Trinity College
Abbott

Unknown

Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery

Esophageal Cancer

Ireland
Irish Clinical Outcomes in Research and Education
The Cleveland Clinic

Unknown

The 'SILVERMAN1' Trial Single Incision Laparoscopic Versus Existing Resection (Minimal Access) for Neoplasia (SILVERMAN 1)

Right Colon Tumors

Ireland
Dublin City University
Royal College of Surgeons, Ireland; Mater Misericordiae University Hospital

Active, not recruiting

Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy (PANO)

Ovarian Cancer | Colon Cancer | Appendix Cancer | Rectum Cancer | Peritoneal Malignancy

Ireland
St Vincent's University Hospital, Ireland

Recruiting

Patient Experiences Following Urinary Diversion as Part of Surgery for Advanced and Recurrent Rectal Cancer (Pelvex 3)

Quality of Life | Patient Participation | Patient Satisfaction

Ireland
Cancer Trials Ireland

Unknown

Study of Blood and Urine Samples in Patients With Newly Diagnosed Localized Prostate Cancer Treated With Hormone Therapy and Radiation Therapy. ICORG 06-15

Prostate Cancer

Ireland

Clinical Trials on Optic Nerve Neoplasms in Ireland

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