Clinical Trials on Optic Nerve Disorders

Total 153043 results

Qlaris Bio, Inc.

Not yet recruiting

Qlaris Phase 2 Study in NTG Patients

Glaucoma | Normal Tension Glaucoma (NTG) | Low-Tension Glaucoma, Bilateral | Low-Tension Glaucoma, Unspecified Eye

Korea, Republic of, Philippines
Children's Hospital of Philadelphia
Children's Anesthesiology Associates, Ltd.

Withdrawn

Ultrasound Description of the Sciatic Nerve

Sciatic Nerve AH | Peripheral Nerves US
National Taiwan University Hospital

Unknown

Anatomy Study in Control Nerve From Normal Human

Anatomy of Normal Human Nerves | Microscopic Study | Myelinated Nerve and Unmyelinated Nerve Study

Taiwan
Capital Medical University

Unknown

Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales

Papilledema | Cerebral Venous Sinus Thrombosis | CSF Pressure Increased

China
Universitaire Ziekenhuizen KU Leuven
FRO (Funds for Research in Ophthalmology, Belgium)

Unknown

Metabolomics in Surgical Ophthalmological Patients (MISO)

Low Tension Glaucoma | Primary Open-angle Glaucoma

Belgium
Medical University of Vienna

Withdrawn

Role of Endothelin- and Nitric Oxide-system in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure

Ocular Physiology | Regional Blood Flow | Optic Disk

Austria
Medical University of Vienna

Terminated

Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging

Primary Open Angle Glaucoma | Ocular Hypertension | Normal Tension Glaucoma

Austria
Istanbul University - Cerrahpasa (IUC)

Completed

Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring

Intracranial Hypertension | Optic Nerve Sheath Diameter | ICP (Intracranial Pressure) Increase

Turkey
Wills Eye
Optovue

Completed

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Primary Open-angle Glaucoma | Normal Tension Glaucoma | Glaucoma; Drugs

United States
Capital Medical University

Unknown

Endovascular Stenting Treatment for Patients With Internal Jugular Vein Stenosis

Headache | Intracranial Hypertension | Tinnitus | Visual Impairment | Stent Stenosis | Papilledema
Trakya University

Completed

Different Intra-abdominal Pressures and Optic Nerve Size

Major Surgery | Intraabdominal Hypertension | Optic Nerve Congestion

Turkey
Southeast Clinical Research Associates, LLC
Genentech, Inc.

Completed

Efficacy of Biweekly Ranibizumab (0.5 mg) for Exudative Macular Degeneration Retinal Edema Refractory to Anti-VEGF

Exudative Age Related Macular Degeneration

United States
McGill University Health Centre/Research Institute...

Recruiting

Monogenic Diabetes Misdiagnosed as Type 1 (ADDAM)

Diabetes Mellitus, Type 1 | Wolfram Syndrome | Neonatal Diabetes | Monogenic Diabetes | Maturity-onset Diabetes in the Young (MODY) | Wolcott-Rallison Syndrome | Mitochondrial Diabetes

Canada
Benha University

Recruiting

Optic Nerve Sheath Diameter in Pre-Eclamptic Parturient Receiving Magnesium Sulfate Combined With Dexmedetomidine

Optic Nerve Sheath Diameter | Preeclampsia Severe

Egypt
Rigmor Højland Jensen
Odense University Hospital; Rigshospitalet, Denmark; University of Copenhagen

Recruiting

The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure (IIH:DUAL)

Obesity | Weight Loss | Idiopathic Intracranial Hypertension | Papilledema | Intracranial Pressure | Pseudotumor Cerebri Syndrome

Denmark
University of Bern
Novartis; University Hospital Inselspital, Berne; Schweizerische Multiple Sklerose... and other collaborators

Recruiting

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica Spectrum Disorder | CNS Sarcoidosis | CNS Vasculitis | Transverse Myelitis | Rasmussen Encephalitis | Acute Disseminated Encephalomyelitis | Anti-NMDAR Encephalitis | Anti-GAD65 Associated Autoimmune Encephalitis | Anti-AMPAR-1/2 Associated Autoimmune... and other conditions

Switzerland
Santen Pharmaceutical Asia Pte. Ltd.

Recruiting

Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl (NOPAPS)

Ocular Hypertension | Primary Open-angle Glaucoma | Normal Tension Glaucoma | Glaucoma, Suspect

Korea, Republic of
Sanofi

Completed

Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis

Multiple Sclerosis | Neuritis | Optic Nerve

United States
Beth Israel Deaconess Medical Center
Biogen

Completed

Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis (CHAMPIONS10)

Multiple Sclerosis | Optic Neuritis | Transverse Myelitis | Acute Brainstem/Cerebellar Syndrome

United States, Canada
NYU Langone Health
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

neurofibromatosis1 (NF1) | Recurrent or Progressive Optic Pathway Gliomas (OPG) | Recurrent or Progressive Low-grade Glioma

United States
University of Oxford

Completed

Visual and Functional Assessment in Low Vision Patients

Age-related Macular Degeneration | Retinitis Pigmentosa | Inherited Retinal Dystrophies | Optic Nerve Pathology

United Kingdom
Assistance Publique Hopitaux De Marseille

Unknown

Protocol for Evaluating a Planning Algorithm for Gamma Knife Radiosurgery (SPEED)

Brain Metastases | Vestibular Schwannoma | Para-optic Meningioma

France
St. Jude Children's Research Hospital

Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Glioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid Astrocytoma

United States
Wenzhou Medical University

Recruiting

Comparison of the Efficacy of Intraocular Lens Optic Capture and In-the-bag Implantation Over 1 Year in Children With Congenital Cataract

Congenital Cataract | Intraocular Lens Implantation | Optic Capture

China
Hoffmann-La Roche
Shanghai Roche Pharmaceutical Co., Ltd

Recruiting

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
Fred Hutchinson Cancer Center

Active, not recruiting

Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

Myasthenia Gravis | Neuromyelitis Optica | Autoimmune Disease | Chronic Inflammatory Demyelinating Polyneuropathy | Lambert Eaton Myasthenic Syndrome | Cerebellar Degeneration | Stiff Person Syndrome | Opsoclonus Myoclonus Syndrome | Neurologic Autoimmune Disease | Autologous Transplant Autoimmune | Multiple... and other conditions

United States
Centre Hospitalier de Valence

Completed

GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

Sensation Disorders | Taste Disorders | Taste, Metallic | Taste Disorder, Glossopharyngeal Nerve

France
Valley Retina Institute

Completed

Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study (PRESERVE)

Diabetic Macular Edema

United States
Northwell Health

Not yet recruiting

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

Obstructive Sleep Apnea | Normal Tension Glaucoma

United States
Kyorin University

Completed

Vitrectomy for Optic Disc Pit Maculopathy

Optic Disc Pit Maculopathy

Japan
Belfast Health and Social Care Trust
National Institute for Health Research, United Kingdom

Completed

Effectiveness of Multimodal Imaging for the Evaluation of Retinal Oedema And New vesseLs in Diabetic Retinopathy (EMERALD)

Diabetic Macular Edema | Proliferative Diabetic Retinopathy

United Kingdom
Lawson Health Research Institute

Completed

Ocular Manifestations in Rheumatic Diseases

Uveitis | Macular Edema | Retinal Vein Occlusion | Retinitis | Orbital Diseases | Optic Neuritis | Keratoconjunctivitis Sicca | Conjunctivitis | Blindness | Xerophthalmia | Papilledema | Iridocyclitis | Retinal Artery Occlusion | Amaurosis Fugax | Scleritis | Eye Hemorrhage | Chorioretinitis | Choroid Hemorrhage
Rabin Medical Center

Unknown

Protective Effect of Phenytoin on Glaucoma

Primary Open Angle Glaucoma | Normal Tension Glaucoma | Secondary Open Angle Glaucoma | Narrow-Angle Glaucomas

Israel
M.D. Anderson Cancer Center

Recruiting

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Chronic Knee Pain | Peripheral Nerve Stimulation | Genicular Nerves

United States
University of Rzeszow

Completed

The Use of i/t Curve in Assessment of Phototherapy Effects

Nerve Disorders
Chang Gung Memorial Hospital

Unknown

IAN Injury After BSSO in Oral Clefts

Third Division of Fifth Cranial Nerve Disorder

Taiwan
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
Dr. Martin Leitritz
Optomed

Completed

Comparison of Non-mydriatic Camera Systems in a Female Health Hospital

Eye Diseases | Retina; Lesion | Optic Disc Structural Anomaly

Germany
Abbott Medical Devices

Completed

Lead Registry for Optim Leads (OPTIMUM)

Optim Lead Insulation Related Adverse Events

United States, Belgium, Germany
Universitaire Ziekenhuizen KU Leuven

Unknown

Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.

Neurofibromatosis Type 1

Belgium
National Institute of Arthritis and Musculoskeletal...

Terminated

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

Nervous System Malformations | Urticaria | Papilledema | Arthropathy, Neurogenic

United States
First Affiliated Hospital of Harbin Medical University

Unknown

A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy

Oculomotor Nerve Palsy | Trochlear Nerve Palsy | Abducens Nerve Paralysis
Zhang Nina

Not yet recruiting

Randomized Controlled Study of Optical 3D Navigated Repetitive Transcranial Magnetic Stimulation for Achalasia.

Esophageal Achalasia | Functional Magnetic Resonance Imaging | Transcranial Magnetic Stimulation, Repetitive | Vagus Nerve Motor Disorder

China
Stanford University
University of California, San Diego

Completed

Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction

Covid19 | Olfactory Nerve Diseases | Olfaction Disorders | Olfactory Disorder | Olfactory Nerve Injuries | Olfactory Nerve Disorder | Post-Viral Disorder

United States
Boston Children's Hospital
National Eye Institute (NEI); Howard Hughes Medical Institute

Recruiting

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Ocular Motility Disorders | Facial Palsy | Synkinesis | Sixth Nerve Palsy | Mobius Syndrome | Congenital Fibrosis of Extraocular Muscles | Duane Retraction Syndrome | Duane Radial Ray Syndrome | Brown Syndrome | Marcus Gunn Syndrome | Strabismus Congenital | Horizontal Gaze Palsy | Horizontal Gaze Palsy With Progressive... and other conditions

United States
University College, London
National Institutes of Health (NIH)

Not yet recruiting

Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve (EITsVNS)

Epilepsy | Vagus Nerve Diseases | Vagus Nerve Autonomic Disorder
First Affiliated Hospital of Harbin Medical University

Unknown

Effects of Ocular Electroacupuncture on Oculomotor Nerve Palsy

Oculomotor Nerve Palsy

China
Hospital for Special Surgery, New York
Oslo University Hospital

Completed

Changes in Skin Conductance Measurement as an Endpoint Monitor for Sympathetic Blocks

Nerve; Disorder, Sympathetic
Visionary Intelligence Ltd.
Peking University First Hospital; Beijing Municipal Science & Technology Commission

Completed

Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph

Diabetic Retinopathy | Retinal Vein Occlusion | Retinitis Pigmentosa | Optic Atrophy | Retinal Detachment | Epiretinal Membrane | Macular Holes | Central Serous Chorioretinopathy | Retinal Artery Occlusion | Suspect Glaucoma | Pathologic Myopia | Nonexudative Age-related Macular Degeneration | Exudative Age Related...

China

Clinical Trials on Optic Nerve Disorders

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