Clinical Trials on Osteoarthritis; Primary in South Africa

Total 3728 results

Minervax ApS
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV

Group B Streptococcal Infection

South Africa, Uganda
Ipas

Terminated

Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa

Abortion, Induced | Abortion, Incomplete

Mexico, South Africa
Hasanuddin University

Completed

Prolotherapy Intervention Effect in Patient With Knee Osteoarthritis

Knee Osteoarthritis

Indonesia
University of KwaZulu
Centre for the AIDS Programme of Research in South Africa

Recruiting

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB (ORCHID)

Tuberculosis | Hiv

South Africa
Canary Medical

Enrolling by invitation

A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

Knee Osteoarthritis

United States
University of California, Los Angeles
University of Cape Town

Active, not recruiting

Evaluation of Pre-Exposure Prophylaxis (PrEP) in Pregnant and Breastfeeding Women (PrEP-PP)

HIV-I Infection

South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
University of Witwatersrand, South Africa
Bill and Melinda Gates Foundation

Completed

Immunogenicity and Safety of Trivalent Influenza Vaccine in Non-pregnant HIV-infected Women

Influenza | Human Immunodeficiency Virus

South Africa
Endocyte

Recruiting

Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer

Prostatic Neoplasms, Castration-Resistant

Australia, South Africa
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Centre for the AIDS Programme of Research in South...
Doris Duke Charitable Foundation

Completed

An Enhanced Adherence Support Programme for Highly Active Antiretroviral Therapy (HAART) (eASP)

HIV Infections

South Africa
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
The Hawkins Foundation
BREG, Inc

Completed

Effectiveness of BREG Flex in 12-week Peri-operative Total Knee Arthroplasty

Knee Osteoarthritis

United States
French National Agency for Research on AIDS and...

Completed

Evaluation of the Extension at Community Level of Safe Male Circumcision (ANRS 12126 ORANGE FARM 2) (ORANGE FARM 2)

HIV Infections

South Africa
The Hawkins Foundation
Integra LifeSciences Corporation

Completed

Steroid Injection vs. BioDRestore for Patients With Knee OA

Knee Osteoarthritis

United States
The Hawkins Foundation

Withdrawn

Exparel vs Exparel Plus ACB in TKAs

Knee Osteoarthritis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Acceptability, Safety, and Use of Daily Truvada Pre-Exposure Prophylaxis in Adolescents

HIV Infections

South Africa
New York State Psychiatric Institute
Brown University; Medical Research Council, South Africa

Active, not recruiting

A Gender-Enhanced Pre-Exposure Prophylaxis (PrEP) Information-Motivational Workshop for Young South African Women (Masibambane)

HIV Infections

South Africa
Gritstone bio, Inc.

Completed

Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)

COVID-19 | SARS-CoV-2

South Africa
RTI International
Medical Research Council, South Africa

Completed

Cape Town Young Women's Health CoOp

Human Immunodeficiency Virus (HIV) | Condomless Sex | Alcohol and Drug Use | Sexually Transmitted Infections (STIs) | Violence and Victimization | Access and Linkage to Healthcare | Education Advancement

South Africa
ANRS, Emerging Infectious Diseases
University of KwaZulu; Africa Centre For Health and Population Studies

Completed

Impact of Immediate Versus South African Recommendations Guided ART Initiation on HIV Incidence (TasP)

HIV Infection

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Johns Hopkins Bloomberg School of Public Health
National Institute of Mental Health (NIMH); Unity Health Toronto; TB/HIV Care

Recruiting

Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa

HIV Infections | Pre-exposure Prophylaxis

South Africa
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa (RESOLVE)

HIV Infections | AIDS | Virologic Failure

South Africa, Uganda
Medical Research Council, South Africa
National Institute of Mental Health (NIMH)

Completed

Stepping Stones Program for Preventing HIV Infection in Residents of Rural South African Communities

HIV Infections

South Africa
French National Agency for Research on AIDS and...

Terminated

Effect of Male Circumcision on HIV Incidence (ANRS 1265)

HIV Infections | Herpes Genitalis | Venereal Diseases

South Africa
Africa Health Research Institute

Recruiting

Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT (LAPIS)

HIV Infections

South Africa
University of Sussex
University of Cape Town; Africa Health Research Institute

Not yet recruiting

Optimised Electronic Patient Records to Improve Clinical Monitoring of HIV-positive Patients in Rural South Africa (MONART)

HIV Infections

South Africa
London School of Hygiene and Tropical Medicine
Department for International Development, United Kingdom; University of Witwatersrand... and other collaborators

Completed

The Intervention With Microfinance for AIDS and Gender Equity (IMAGE) Study

HIV Infections | Gender Based Violence

South Africa
Walter Sisulu University
Medical University of Graz; Nelson Mandela Academic Hospital; Umtata General...

Not yet recruiting

Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero (ARTMOMSBABES)

In Utero Drug Exposure

South Africa
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

GUD Clinical and Virologic Response to Acyclovir in HIV Negative African Women (PK/GUD)

Genital Herpes

South Africa, Zambia
bioLytical Laboratories

Recruiting

Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care Sites

Syphilis | Syphilis Infection

South Africa
bioLytical Laboratories

Active, not recruiting

Retrospective Study of iStatis Syphilis Ab Test (POC)

Syphilis | Syphilis Infection

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Strategies for Delivering Anti-HIV Therapy in South Africa

HIV Infections

South Africa
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Point-of-care Viral Load Testing to Enable Streamlined Care and Task Shifting for Chronic HIV Care (STREAM)

Chronic HIV Infection

South Africa
Boston University
National Institute of Mental Health (NIMH); Africa Health Research Institute

Completed

Life Plans Intervention Study

HIV/AIDS | Health Knowledge, Attitudes, Practice | Chronic HIV Infection

South Africa
Elizabeth Glaser Pediatric AIDS Foundation
Harvard School of Public Health (HSPH); Centre for Infectious Disease Research... and other collaborators

Completed

Elizabeth Glaser Pediatric AIDS Foundation Maternal Events and Pregnancy Outcomes (MEP Project)A Multi-site Protocol (MEPProject)

HIV Infections | Pregnant Women | HIV Positive

South Africa, Zambia
Boehringer Ingelheim

Completed

Open Label Study of NVP+CBV Treatment in Women Who Have Received sdNVP for the pMTCT of HIV

Acquired Immunodeficiency Syndrome

South Africa
Centre for the AIDS Programme of Research in South...
MIET Africa; KwaZulu-Natal Department of Education; Embassy of the Kingdom of...

Completed

Reducing HIV in Adolescents (RHIVA)

HIV Infections

South Africa
University of Houston
Michigan State University; Bar-Ilan University, Israel; University of the Free...

Completed

MISC-CBO in Children Affected by HIV/AIDS

HIV Affected Children (Single and/or Double Orphans)

South Africa
University of KwaZulu
Bristol-Myers Squibb

Completed

Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women

Puerperal Sepsis

South Africa
Massachusetts General Hospital
Depuy, Inc.

Unknown

Massachusetts General Hospital Evaluation of DePuy ASR Hip System

Osteoarthritis

United States, United Kingdom, Australia, Italy, South Africa
Columbia University
Bill and Melinda Gates Foundation; University of Cape Town; EngenderHealth

Terminated

Screen and Treat for Cervical Cancer Prevention (SAT)

Cervical Cancer

South Africa
Africa Health Research Institute

Completed

Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal

HIV Prevention

South Africa
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Centre for the...

Recruiting

Simplifying Treatment and Monitoring for HIV (STREAM HIV)

HIV/AIDS | HIV-1-infection

South Africa
University of Maryland, College Park
Canadian Institutes of Health Research (CIHR); University of Washington; Swiss... and other collaborators

Completed

Pilot Test of a Couple-Based Medication Adherence Intervention for HIV-Positive Women and Their Male Partners in South Africa

Human Immunodeficiency Virus

South Africa
University of California, Los Angeles
Medical University of South Carolina; Charles University, Czech Republic; Human...

Completed

Bringing South African Men Into HIV Counseling and Testing and Care

Human Immunodeficiency Virus

South Africa
Massachusetts General Hospital
Bill and Melinda Gates Foundation

Recruiting

Delivery Optimization for Pre-Exposure Prophylaxis (DO PrEP) Study

HIV | Human Immunodeficiency Virus | ART

South Africa

Clinical Trials on Osteoarthritis; Primary in South Africa

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