Clinical Trials on Osteopenia or Osteoporosis in South Africa

Total 1659 results

Hoffmann-La Roche

Completed

PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia

Postmenopausal Osteoporosis

United States
Hoffmann-La Roche

Completed

A Study of Ibandronate (Boniva) to Evaluate Satisfaction in Women With Post-Menopausal Osteoporosis or Osteopenia

Postmenopausal Osteoporosis

United States
Pfizer

Completed

Safety And Tolerability Study Of RN564 In Women With Osteopenia And Healthy Men.

Osteoporosis | Osteopenia | Bone Disease

United States
St Vincent's Hospital, Sydney
Merck Sharp & Dohme LLC; The Alfred; Holdsworth House Medical Practice

Completed

Switch From Tenofovir to Raltegravir for Low Bone Mineral Density (TROP)

HIV Infections | HIV | Osteoporosis | Osteopenia

Australia
Novartis

Completed

To Assess the Efficacy of Over-the-counter Analgesics in the Prevention/Treatment of Transient Post-dose Symptoms Following Zoledronate Infusion in Post-menopausal Women

Osteopenia

United States, Australia, Canada, Russian Federation, South Africa
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Alvotech Swiss AG

Completed

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase I Study Conducted in Healthy Volunteers

United Kingdom, South Africa, Poland
Sanofi
Procter and Gamble

Completed

Risedronate 75mg Dosed on 2 Consecutive Days Monthly in the Treatment of Osteoporosis in Postmenopausal Women

Osteoporosis Postmenopausal

France, United States, Australia, Canada, Lebanon, South Africa, Czech Republic, Turkey, Argentina, Poland, United Kingdom
Brown University

Completed

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
Novartis Pharmaceuticals

Completed

1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids

Osteoporosis

Australia, Canada, Russian Federation, Hungary, South Africa, United Kingdom
Novartis Pharmaceuticals

Completed

An Efficacy and Safety Trial of Intravenous Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids

Osteoporosis

Australia, Canada, Russian Federation, Hungary, South Africa, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Procter and Gamble

Completed

Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects

Post-menopausal Osteoporosis

United Kingdom
Alvotech Swiss AG

Active, not recruiting

Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND (ALVOBOND)

Osteoporosis, Postmenopausal

South Africa, Bulgaria, Czechia, Georgia, Poland
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
University of Johannesburg

Completed

Routine Versus Selective Midtrimester Ultrasound in a Poorly Resourced Setting: a Cluster Randomised Controlled Trial

Fetal Congenital Abnormalities | Prolonged Pregnancy | Multiple Pregnancy

South Africa
University of the Western Cape

Completed

Interventions for Patients With a Shortened Dental Arch (SDA-RCT)

Anomaly of Dental Arch

South Africa
BioGaia AB

Completed

Evaluation and Comparison of 2 Cosmetic Investigational Products in Adults With Atopic Dermatitis

Atopic Dermatitis

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Resolution of Effect of Bisphosphonates on Bone in Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

United Kingdom
GLYCAR SA (Pty) Ltd

Recruiting

Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)

Cardiac Anomaly | Cardiac Defect | Pericardial Defect

South Africa
Novartis

Completed

A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis

Atopic Eczema

South Africa
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
University of KwaZulu

Completed

Isolated Vascularized Gastric Tube Biliary Enteric Drainage: A Paediatric Case Series Experience.

Biliary Obstruction | Choledochal Cyst

South Africa
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Stellenbosch and other collaborators

Completed

The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology

Fetal Alcohol Spectrum Disorders

South Africa
University of KwaZulu
Cambridge University Hospitals NHS Foundation Trust; University of Oxford; University...

Completed

Durban Diabetes Study:A Study of the Epidemiology of Diabetes Mellitus in Urban South Africans of African Descent (DDS) (DDS)

Hyperglycemia | Diabetes Mellitus | Glucose Intolerance | Hereditary Diseases

South Africa
Duke University
University of Cape Town

Recruiting

Autism Caregiver Coaching in Africa (ACACIA)

Autism or Autistic Traits

South Africa
Tarsa Therapeutics, Inc.

Completed

A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women (ORACAL)

Osteoporosis, Postmenopausal

United States, United Kingdom, Bulgaria, Hungary, Poland, South Africa
Hoffmann-La Roche

Completed

A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Who Have Received Previous Bonviva Treatment

Post-Menopausal Osteoporosis

Spain, South Africa, Germany, Mexico, Italy, Belgium, United States, Poland, Denmark, Hungary, Czech Republic, France, Norway, United Kingdom, Australia
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
Hoffmann-La Roche

Completed

DIVA Study - A Study of Different Regimens of Intravenous Administration of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis

Post Menopausal Osteoporosis

Spain, South Africa, Germany, Mexico, United States, Canada, France, United Kingdom, Italy, Belgium, Australia, Poland, Denmark, Hungary, Czech Republic, Norway
University of Stellenbosch
Stanford University

Completed

Transcutaneous Screening for Risk of Severe Hyperbilirubinemia in South African Newborns

Hyperbilirubinemia | Neonatal Jaundice

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioavailability Food-Effect Study of an Oral Nitisinone Formulation to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Eclampsia

Eclampsia

South Africa
AstraZeneca

Completed

Type III Dysbetalipoproteinemia

Hyperlipoproteinemia Type III

South Africa, Norway
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Oral Nitisinone Formulations to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
University of Houston
Michigan State University; Bar-Ilan University, Israel; University of the Free...

Completed

MISC-CBO in Children Affected by HIV/AIDS

HIV Affected Children (Single and/or Double Orphans)

South Africa
Red Cross War Memorial Childrens Hospital

Completed

Accessible and Affordable Moisturizers for Atopic Eczema

Childhood Atopic Dermatitis

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Nitisinone Formulations Compared to Orfadin

Hereditary Tyrosinemia, Type I

South Africa
Bayer

Completed

HPA Axis Study in Adults

Eczema | Atopic Dermatitis

South Africa
Bayer

Completed

Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

Atopic Dermatitis

South Africa
Amgen

Completed

Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss

Cancer | Cataract | Prostate Cancer | Osteoporosis | Osteopenia | Low Bone Mineral Density

United States, Canada, Czechia, Poland, Russian Federation, Slovakia, Hungary, South Africa, Greece, Bulgaria, France, Ukraine, Australia, Latvia, India, Slovenia, New Zealand, Mexico
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
University of Stellenbosch
Fogarty International Center of the National Institute of Health

Unknown

Neonatal Bacterial Colonization Study

Prematurity | Bloodstream Infection | Neonatal SEPSIS | Very Low Birth Weight Baby

South Africa
Medical University of South Carolina
Merck Sharp & Dohme LLC; FDA Office of Orphan Products Development

Completed

Alendronate in Juvenile Osteoporosis

Fractures | Juvenile Osteoporosis | Low Bone Density

United States
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
Desmond Tutu HIV Foundation
National Institutes of Health (NIH); University of Cape Town; Zeteo Tech Incorporated

Completed

Bioaerosol Sampling in Suspected Pulmonary Tuberculosis

Pulmonary Tuberculosis Confirmation by Sputum Microscopy With or Without Culture

South Africa
Medical University of South Carolina
Merck Sharp & Dohme LLC

Completed

Phase II Study of Alendronate Sodium in Children With High-Turnover Idiopathic Juvenile Osteoporosis

Osteoporosis

United States
Hoffmann-La Roche

Completed

MOBILE Study - A Study of Bonviva (Ibandronate) Regimens in Women With Post-Menopausal Osteoporosis

Post Menopausal Osteoporosis

Australia, United Kingdom, United States, Brazil, Germany, South Africa, France, Spain, Switzerland, Italy, Canada, Hungary, Belgium, Mexico, Poland, Denmark, Norway, Czechia, Romania
Hoffmann-La Roche

Completed

A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.

Post-Menopausal Osteoporosis

Switzerland, United States, Brazil, Mexico, South Africa, Argentina

Clinical Trials on Osteopenia or Osteoporosis in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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