Clinical Trials on Osteosarcoma

Total 535 results

University Hospital, Strasbourg, France

Completed

Genetic Characterisation of High-grade Paediatric Osteosarcomas

Paediatric Osteosarcomas

France
Klinikum Stuttgart
Klinikum Kassel GmbH (COSS-Biobank)

Not yet recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry)

Osteosarcoma | High Grade Sarcoma | Recurrent Osteosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma | Bone Tumor | Extraskeletal Osteosarcoma | Osseous Sarcoma | Parosteal Osteosarcoma | Osteoblastic Osteosarcoma | Chondroblastic Osteosarcoma | Fibroblastic Osteosarcoma | Conventional Osteosarcoma | Conventional... and other conditions
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma

United States, Canada, Puerto Rico
M.D. Anderson Cancer Center

Suspended

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Unresectable Osteosarcoma | Locally Advanced Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | Unresectable Osteosarcoma | Resectable Osteosarcoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma | Osteoblastic Osteosarcoma

United States
National Cancer Institute (NCI)

Suspended

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | High Grade Osteosarcoma | Secondary Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Blood Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Sarcoma Alliance for Research through Collaboration

Active, not recruiting

SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

Osteosarcoma | Osteosarcoma Recurrent | Osteosarcoma Metastatic | Osteosarcoma in Children

United States
UNICANCER

Recruiting

A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas (REGOBONE)

Chondrosarcomas | Ewing Sarcomas | Osteosarcomas | Chondroma | CIC-Rearranged Sarcoma

France
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Recurrent Ewing Sarcoma | Recurrent Osteosarcoma | Stage III Osteosarcoma AJCC v7 | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Metastatic Ewing Sarcoma | Unresectable Ewing Sarcoma | Unresectable Osteosarcoma

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Istituto Ortopedico Rizzoli

Completed

an Istitution Experience on Parosteal OsTeosarcoma

Parosteal Osteosarcoma

Italy
Italian Sarcoma Group

Completed

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma (SERIO)

Metastatic Osteosarcoma | Relapsed Osteosarcoma

Italy
Beijing Immunochina Medical Science & Technology...
Guangdong Provincial People's Hospital

Not yet recruiting

IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

China
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Osteosarcoma Recurrent | Osteosarcoma Metastatic

Italy
Ipsen

Not yet recruiting

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma (CabOSTar)

Osteosarcoma | Osteosarcoma in Children | Osteosarcoma in Adolescents and Young Adults
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

United States
Dana-Farber Cancer Institute

Completed

Cabozantinib With Topotecan-Cyclophosphamide

Refractory Ewing Sarcoma | Refractory Osteosarcoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma (DOSa)

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Metastatic Angiosarcoma | Recurrent Dedifferentiated Liposarcoma | Metastatic Dedifferentiated Liposarcoma | Recurrent Angiosarcoma | Refractory Dedifferentiated Liposarcoma

United States
National Cancer Institute (NCI)

Completed

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Metastatic Malignant Neoplasm in the Lung

United States, Canada, Puerto Rico, Australia, New Zealand
Italian Sarcoma Group

Terminated

Phase II Trial for the Treatment of Relapsed Osteosarcoma (OsteoREC2015)

OSTEOSARCOMA

Italy
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Active, not recruiting

Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

Sarcoma | Osteosarcoma | Osteosarcoma Recurrent | Osteosarcoma in Children

United States
Italian Sarcoma Group
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Observational Study in Localized Osteosarcoma (ISG Os2Oss)

Localized Osteosarcoma

Italy
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Refractory Osteosarcoma

United States
National Cancer Institute (NCI)

Completed

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Metastatic Osteosarcoma

United States
Université de Reims Champagne-Ardenne

Recruiting

Neutrophils in Bone Sarcomas (TANOs)

Osteosarcoma, Chondrosarcoma

France
Lee's Pharmaceutical Limited

Not yet recruiting

Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy

High-grade Osteosarcoma
Peking University People's Hospital

Recruiting

Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

Osteosarcoma of Pelvis

China
Sidnei Epelman

Unknown

Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma

Refractory or Relapsed Osteosarcoma

Brazil
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Terminated

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Metastatic Osteosarcoma

United States
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.

Osteosarcoma, Advanced

China
Istituto Ortopedico Rizzoli

Recruiting

Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study (Micros)

Localized Osteosarcoma

Italy
George Clinical Pty Ltd
Novartis

Terminated

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Osteosarcoma | Metastatic Osteosarcoma

United States
University of Florida
The V Foundation for Cancer Research

Not yet recruiting

Study of RNA-lipid Particle (RNA-LP) Vaccines for Recurrent Pulmonary Osteosarcoma (OSA)

Pulmonary Osteosarcoma
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

An Analysis of the Efficacy of High Dose Isofosfamide Through Elastomer

Osteosarcoma Recurrent

Italy
The University of Hong Kong

Unknown

The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors

Childhood Osteosarcoma

Hong Kong
Prof. Franca Fagioli

Suspended

Qarziba for Patients in Relapsed/Refractory High-grade Osteosarcoma

Osteosarcoma in Children

Italy
Yuxi Su

Completed

3D Printed Personalized Extendable Prosthesis

Osteosarcoma in Children

China
Grupo de Apoio ao Adolescente e a Crianca com Cancer

Unknown

Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity

High Grade Osteosarcoma

Brazil
Case Comprehensive Cancer Center

Recruiting

Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma

Pulmonary Metastatic Osteosarcoma (pOS)

United States
University of Arkansas

Terminated

Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity

Radiation Toxicity | Osteosarcoma in Children

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States, Canada
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Osteosarcoma | Localised High Grade Osteosarcoma of the Limbs

France
China Association of Osteosarcoma Chemotherapy

Unknown

A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma

Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma
University Hospital, Strasbourg, France

Recruiting

Integrated Clinical-radiological Analysis of Hypoxia Markers in Pediatric Osteosarcomas (SARCOMAS)

Osteosarcoma in Children

France
Insmed Incorporated

Completed

Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung

Osteosarcoma Metastatic

United States
Istituto Ortopedico Galeazzi

Unknown

Inhibition of SENP1 for the Suppression of OS Growth and Metastasis

Primary Osteosarcoma of Bone

Italy

Clinical Trials on Osteosarcoma

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