Clinical Trials on PTCH1 or SMO Activated Solid and Hematologic Tumors in United States
Total 445 results
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Novartis PharmaceuticalsTerminatedPTCH1 or SMO Activated Solid and Hematologic TumorsUnited States
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Novartis PharmaceuticalsCompletedCancer Patients With Advanced Solid Tumors Including Lymphoma or Chronic Hematological MalignanciesUnited States
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Endeavor Biomedicines, Inc.Active, not recruitingSolid Tumors With PTCH1 Loss-of-function MutationsUnited States
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Rhode Island HospitalUnknownSolid Tumors | Hematological MalignanciesUnited States
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Inova Health Care ServicesRecruitingSolid Tumor | Hematological MalignancyUnited States
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Acrotech Biopharma Inc.Axis Clinicals LimitedCompletedSolid Tumors | Hematological MalignanciesUnited States
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Ascentage Pharma Group Inc.RecruitingAdvanced Solid Tumors or Hematologic MalignanciesUnited States
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Synta Pharmaceuticals Corp.CompletedLymphoma | Leukemia | Hematological Malignancies | Metastatic or Unresectable Solid TumorsUnited States
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Spectrum Pharmaceuticals, IncOnxeoCompletedSolid Tumor | Hematological MalignancyUnited States
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Scripps Translational Science InstituteCompleted
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Acrotech Biopharma Inc.Axis Clinicals LimitedCompletedSolid Tumor | Hematological MalignanciesUnited States
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Century Therapeutics, Inc.RecruitingHematological Malignancy | Solid Tumor MalignancyUnited States
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St. Jude Children's Research HospitalCompleted
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Memorial Sloan Kettering Cancer CenterActive, not recruitingSolid Tumor | Hematologic Malignancy | Solid Tumor, Adult | Solid CarcinomaUnited States
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Constellation PharmaceuticalsCompletedSolid Tumor | Advanced Malignancies | Hematological MalignancySpain, United States, Georgia
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Mayo ClinicRecruitingSolid Tumors | Hematologic MalignanciesUnited States
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AstraZenecaActive, not recruitingPediatric Cancer | Hematological Malignancies | Solid Tumor PediatricSpain, Italy, United States, United Kingdom, France, Netherlands, Germany
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Incyte CorporationCompletedSolid Tumors and Hematologic MalignancyUnited States
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National Cancer Institute (NCI)Enrolling by invitationSolid Tumors | Hematologic Malignancies | Pediatric CancersUnited States
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Acrotech Biopharma Inc.Axis Clinicals LimitedTerminatedRelapsed/Refractory Solid Tumors/Hematological MalignanciesUnited States
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Semafore PharmaceuticalsSignalRX Pharmaceuticals, Inc.CompletedCancer | Advanced or Metastatic Solid Tumors | Solid CancersUnited States
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Incyte CorporationCompletedSolid Tumors and Hematologic MalignancyUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedHematologic Diseases | Solid Tumors | Advanced CancersUnited States
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St. Jude Children's Research HospitalNovartis PharmaceuticalsActive, not recruitingGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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M.D. Anderson Cancer CenterBTG International Inc.Terminated
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Leap Therapeutics, Inc.Cancer Research Institute, New York CityCompletedUnresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor MalignanciesUnited States
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Aadi Bioscience, Inc.RecruitingMalignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic NeoplasmKorea, Republic of, United States, Puerto Rico
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Memorial Sloan Kettering Cancer CenterRecruiting
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City of Hope Medical CenterNational Institute on Aging (NIA)Active, not recruitingCancer | Solid Tumor | Hematologic MalignancyUnited States
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UNC Lineberger Comprehensive Cancer CenterGenentech, Inc.CompletedHematologic Malignancies | Malignant Solid TumorUnited States
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Dialectic Therapeutics, IncCompletedSolid Tumor | Hematologic MalignancyUnited States
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Dartmouth-Hitchcock Medical CenterRecruitingCancer | Hematologic Malignancy | Blood Cancer | Tumor, SolidUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...RecruitingRefractory and/or Relapsed Metastatic Solid TumorsUnited States
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Nucleix Ltd.CompletedCancer | Hematologic Neoplasms | Solid TumorIsrael, United States
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Duke UniversityCompletedA Diagnosis of Any Hematologic or Solid MalignancyUnited States
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Taiho Oncology, Inc.TerminatedAdvanced Solid Tumors With HER2 Abnormalities | Advanced Solid Tumors With HER3 AbnormalitiesUnited States, Spain, France, United Kingdom
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Community Cancer CareAmgenUnknownCancer | Solid Tumor | Hematologic MalignancyUnited States
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Millennium Pharmaceuticals, Inc.CompletedAdvanced Solid Tumors | Hematologic MalignanciesUnited States
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CytomX TherapeuticsTerminatedSolid Tumor | Unresectable or Metastatic MelanomaKorea, Republic of, United States, Netherlands, Spain, Australia
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MedImmune LLCCompletedRecurrent or Metastatic Solid TumorsUnited States, Australia
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Merck Sharp & Dohme LLCRecruitingAdvanced or Metastatic Solid TumorsCanada, Switzerland, United States
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National Cancer Institute (NCI)TerminatedUnspecified Adult Solid Tumor, Protocol Specific | Hematopoietic/Lymphoid CancerUnited States
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Merck Sharp & Dohme LLCRecruitingAdvanced or Metastatic Solid TumorsUnited States, Canada, Israel, Netherlands
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St. Jude Children's Research HospitalRecruitingCancer | Hematologic Malignancy | Solid Organ Transplant | Hematopoietic Cell Transplant | Solid Tumor Malignancy | Hematopoietic System--Cancer | Transplant-Related Cancer | Cellular TherapyUnited States
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AmgenCompletedHepatic Impairment | Solid Tumors | Hematologic MalignanciesUnited Kingdom, Netherlands, United States, France
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PfizerTerminatedSolid Tumor | Hematologic MalignanciesUnited States
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Merck Sharp & Dohme LLCRecruitingSolid Tumors | Hematologic MalignanciesUnited States, Poland, Brazil, Ukraine, Argentina, Australia, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic... and more
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New York Medical CollegeTerminatedSarcoma | Neuroblastoma | Wilms' Tumor | Refractory Solid Tumor | Recurrent Solid TumorUnited States
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Memorial Sloan Kettering Cancer CenterMerck Sharp & Dohme LLCActive, not recruitingSolid Tumors | Identified by NGS, PCR or IHCUnited States
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Memorial Sloan Kettering Cancer CenterNational Cancer Institute (NCI)CompletedUnspecified Childhood Solid Tumor, Protocol Specific | Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Retinoblastoma | Extragonadal Germ Cell Tumor | Childhood Germ Cell TumorUnited States