Clinical Trials on Paranasal Sinuses

Total 1009 results

Helsinki University Central Hospital

Active, not recruiting

Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)

Asthma | Nasal Polyps | Aspirin Sensitivity | Sinusitis, Chronic

Finland, Netherlands
Intersect ENT

Completed

Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)

Chronic Sinusitis | Nasal Polyposis

United States
Intersect ENT

Completed

S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps (RESOLVE_II)

Chronic Sinusitis | Nasal Polyposis

United States
Aardvark Medical Company

Completed

Home Usability of a Nasal Lavage System in Children

Sinusitis | Allergic Rhinitis | Nasal Congestion | Respiratory Tract Infection

United States
University of Nebraska

Terminated

Pain Management Following Sinus Surgery

Pain, Postoperative | Opioid Abuse | Nasal Sinus; Inflammation

United States
Johns Hopkins University
GlaxoSmithKline

Recruiting

The Role of IL5 in Epithelial Cell Integrity

Chronic Rhinosinusitis (Diagnosis) | Chronic Rhinosinusitis With Nasal Polyps

United States
Pfizer
Biohaven Pharmaceutical Holding Company Ltd.

Completed

Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis

Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

United States
Washington University School of Medicine

Completed

The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis

Rhinosinusitis | Allergic Rhinosinusitis | Chronic Eosinophilic Rhinosinusitis

United States
University of Wisconsin, Madison

Completed

Gulf War Illness Nasal Irrigation Study (GWINIS)

Fatigue | Chronic Sinusitis | Persian Gulf Syndrome | Acute Sinusitis

United States
University of Jena
Medical University Innsbruck

Completed

Effects of Kalydeco on Upper Airway and Paranasal Sinus Inflammation Measured by Nasal Lavage and on Symptoms (KPNSI)

Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco

Germany
National Cancer Institute (NCI)

Completed

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Tongue Cancer | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell... and other conditions

United States
University of Florida

Recruiting

Functional Endoscopic Sinus Surgery Study (FESS)

Chronic Rhinosinusitis (Diagnosis)

United States
AstraZeneca
Amgen

Active, not recruiting

Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)

Chronic Rhinosinusitis With Nasal Polyps

United States, Canada, Denmark, Spain, United Kingdom, Germany, Hungary, China, Japan, Poland
Beijing Tongren Hospital

Completed

A Study of Different Endoscopic Surgery Procedures in Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Chronic Rhinosinusitis (Diagnosis) | Surgery
Assiut University

Unknown

Radiologic Scoring of Patients With Chronic Sinusitis and Nasal Polyps

Chronic Sinusitis

Egypt
National Cancer Institute (NCI)

Completed

Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx and other conditions

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

Head and Neck Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent... and other conditions

United States
Sun Yat-sen University
Zhongshan People's Hospital, Guangdong, China; Fifth Affiliated Hospital of...

Recruiting

Steroid-Eluting Stent Implant for the Treatment of Radiation-Related Sinusitis

Radiation-Induced Mucositis

China
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Tissue Immune Interaction in Nasal Polyposis (TIP)

Asthma | Chronic Rhinosinusitis (Diagnosis) | Chronic Rhinosinusitis With Nasal Polyps

United States
GB001, Inc, a wholly owned subsidiary of Gossamer...

Completed

GB001 in Adult Participants With Chronic Rhinosinusitis

Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) | Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

United States, Czechia, Ukraine
Johns Hopkins University

Completed

Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis

Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Eosinophilia

United States
Sohag University

Not yet recruiting

Role of Imaging in Complications of Sinusitis

Rhinosinusitis Chronic | Rhinosinusitis | Fungal Sinusitis | Rhinosinusitis Acute | Allergic Fungal Rhinosinusitis | Intracranial Extension | Invasive Fungal Sinusitis (Diagnosis)

Egypt
Beijing Tongren Hospital

Recruiting

CST1 Predictive Model of Oral Glucocorticoid Therapy Sensitivity for Chronic Rhinosinusitis With Polyps

Chronic Rhinosinusitis With Nasal Polyps | Glucocorticoids

China
Engelhard Arzneimittel GmbH & Co.KG
ClinCompetence Cologne GmbH

Completed

Sinolpan® Pharmacy Non-interventional Study - Quality of Live

Bronchitis | Rhinosinusitis Chronic | Rhinosinusitis Acute

Germany
St. Paul's Hospital, Canada

Unknown

Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management

Chronic Sinusitis

Canada
Medical University of Lodz

Completed

Response of the Airway in Sinusitis and Asthma (RAISe)

Asthma | Sinusitis

Poland
JHSPH Center for Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Study of Asthma and Nasal Steroids (STAN)

Asthma | Sinusitis | Rhinitis

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy

Mucositis | Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell Carcinoma of the Paranasal... and other conditions
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
University Medical Centre Ljubljana
University of Ljubljana, Faculty of Medicine

Recruiting

Prospective Study of Sinonasal and Skull-base Tumours Management (Sinonasal_Tu)

Skull Base Neoplasms | Sinus Disease | Nasal Neoplasm | Nasal Neoplasm Benign | Skull Base Osteomyelitis | Sinonasal Disorder

Slovenia
University of Washington
National Cancer Institute (NCI)

Completed

TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Children's Hospital of Philadelphia
Patient-Centered Outcomes Research Institute; University of Pennsylvania; Nationwide... and other collaborators

Active, not recruiting

Broad Implementation of Outpatient Stewardship (BIOS)

Otitis Media | Pharyngitis | Acute Respiratory Tract Infection | Acute Sinusitis

United States
Hannover Medical School

Unknown

Upper and Lower Airway Colonization in Cystic Fibrosis Patients After Lung Transplantation

Paranasal Sinus Diseases | Cystic Fibrosis | Lungtransplantation

Germany
University Hospital, Ghent

Recruiting

Real Life Study of Biologicals in Patients With Severe CRSwNP (NASUMAB)

Chronic Rhinosinusitis With Nasal Polyps

Belgium
Medical University of Vienna

Recruiting

Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps (PREMIUM)

Asthma | Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Chronic Rhinosinusitis With Nasal Polyps

Austria
Washington University School of Medicine

Completed

Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis

Chronic Rhinosinusitis (Diagnosis) | Allergic Rhinosinusitis | Chronic Eosinophilic Rhinosinusitis

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
National Cancer Institute (NCI)

Completed

S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Medical University of Vienna

Not yet recruiting

Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP (EpiBar)

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps

Austria
Assiut University

Not yet recruiting

Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis .

Allergic Fungal Rhinosinusitis
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

Allergic Fungal Rhinosinusitis

China, Argentina, Israel, United States, Canada, India, Japan, Saudi Arabia, Turkey
Ohio State University

Active, not recruiting

3D Printing to Improve Nasal Irrigation Outcome

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps

United States
Janssen Research & Development, LLC

Completed

Fluoroquinolone Associated Disability

Sinusitis | Urinary Tract Infections | Bronchitis

United States
Children's Hospital of Philadelphia

Completed

Antimicrobial Stewardship for Primary Care Pediatricians (PARTI)

Pneumonia | Viral Infection | Streptococcal Pharyngitis | Acute Sinusitis

United States
University of Arizona
National Cancer Institute (NCI)

Completed

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Head and Neck Cancer | Recurrent Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | HNSCC | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma | Stage IVA Nasal Cavity and... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in... and other conditions

Canada
National Cancer Institute (NCI)

Completed

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Universitaire Ziekenhuizen KU Leuven
Regeneron Pharmaceuticals

Recruiting

Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps

Allergic Rhinitis | Chronic Rhinosinusitis With Nasal Polyps

Belgium

Clinical Trials on Paranasal Sinuses

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