Clinical Trials on Parasite IBS IBD in South Africa

Total 127 results

AstraZeneca

Terminated

Open-label Extension Study of Brazikumab in Crohn's Disease (INTREPID OLE)

Crohn's Disease | IBD

United States, Taiwan, Poland, Germany, South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children

HIV Infections | Cryptosporidiosis

South Africa, Thailand
Medicines for Malaria Venture
University of Cape Town

Completed

Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers

Malaria

South Africa
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Meyer Children's Hospital IRCCS

Recruiting

Epidemiological Study on Invasive Bacterial Diseases

Invasive Bacterial Diseases (IBD)

Italy
University of Cape Town
London School of Hygiene and Tropical Medicine

Completed

Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults

HIV | Malaria

South Africa
AstraZeneca

Terminated

An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID)

Crohn's Disease | IBD

United States, Italy, Taiwan, Korea, Republic of, Spain, Germany, Poland, Russian Federation, Israel, Ukraine, Canada, Czechia, South Africa, United Kingdom, Hungary, India, Slovakia
London School of Hygiene and Tropical Medicine
Medical Research Council; University of Witwatersrand, South Africa; National... and other collaborators

Completed

Targeted Indoor Residual Spraying Against Malaria (TIRS)

Malaria

South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine

Completed

Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults (SEACAT 2_4_2)

HIV Infections | Malaria

South Africa
GlaxoSmithKline

Completed

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS)

Germany, Australia, France
National Institute of Environmental Health Sciences...

Completed

Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa

HIV Infections | Malaria | Pregnancy Outcome | Stillbirth | Spontaneous Abortion

South Africa
Oslo University Hospital
University of Copenhagen; Sorlandet Hospital HF; University of Agder; Leiden University... and other collaborators

Unknown

Prevention of Female Genital Schistosomiasis (FGS) in Rural High-endemic South Africa (VIBE-FGS)

Uro-genital Schistosomiasis

South Africa
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease Who Have Failed or Are Intolerant to Tumor Necrosis Factor (TNF) Antagonist Therapy (UNITI-1)

Crohn's Disease | Colitis | Inflammatory Bowel Disease | IBD

United States, France, Poland, United Kingdom, Germany, Spain, Serbia, South Africa, Japan, Israel, Canada, Australia, Netherlands, Korea, Republic of, Belgium, New Zealand, Brazil, Austria, Ireland, Czech Republic, Hungary, Denmark, Icela...
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Ustekinumab Maintenance Therapy in Patients With Moderately to Severely Active Crohn's Disease (IM-UNITI)

Crohn's Disease | Colitis | Inflammatory Bowel Disease | IBD

United States, France, Poland, United Kingdom, Germany, Spain, Israel, Bulgaria, Serbia, South Africa, Japan, Canada, Australia, Netherlands, Korea, Republic of, Belgium, New Zealand, Brazil, Russian Federation, Austria, Hungary, ... and more
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction Therapy in Patients With Moderately to Severely Active Crohn's Disease (UNITI-2)

Crohn's Disease | Colitis | Inflammatory Bowel Disease | IBD

United States, France, Poland, United Kingdom, Germany, Spain, Israel, Bulgaria, Serbia, South Africa, Japan, Australia, Canada, Netherlands, Korea, Republic of, New Zealand, Brazil, Russian Federation, Belgium, Hungary, Croatia, ...
Drexel University
University of North Carolina, Chapel Hill; University of KwaZulu

Completed

MAMAS: Mentoring Adolescent Mothers at School (MAMAS)

Chlamydia | Gonorrhea | Human Immunodeficiency Virus | Trichomonas Vaginitis | Herpes Simplex Type II

South Africa
GlaxoSmithKline

Completed

Randomized Placebo Controlled Efficacy And Safety Study Investigating GW876008 In Patients With Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS)

United States, Canada
Population Council
National Institute of Allergy and Infectious Diseases (NIAID); United States... and other collaborators

Completed

Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission

HIV Infections | Syphilis | Trichomonas Vaginitis | Chlamydia Trachomatis | Neisseria Gonorrhoeae

South Africa
AstraZeneca

Terminated

Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis (Expedition)

Ulcerative Colitis | IBD

United States, Italy, Taiwan, Korea, Republic of, Germany, Spain, Russian Federation, Japan, South Africa, Hungary, Poland, Israel, Puerto Rico, Czechia, Ukraine, United Kingdom, Canada, India, Slovakia
Ardelyx

Enrolling by invitation

Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C

Irritable Bowel Syndrome With Constipation (IBS-C)

United States
Ardelyx

Recruiting

Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years

Irritable Bowel Syndrome With Constipation (IBS-C)

United States
Ono Pharma USA Inc

Completed

A Phase 2, Multi-center Study to Evaluate the Efficacy and Safety of ONO-2952 in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) (RESTORE)

Irritable Bowel Syndrome (IBS)

United States
Alvotech Swiss AG

Completed

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase I Study Conducted in Healthy Volunteers

United Kingdom, South Africa, Poland
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
University of Cape Town
World Health Organization; Medical Research Council, South Africa; Global Fund

Completed

Combination Antimalarials in Uncomplicated Malaria

Malaria

Mozambique, South Africa, Swaziland
National Institute of Allergy and Infectious Diseases...

Completed

Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso

Malaria

Burkina Faso
GlaxoSmithKline

Completed

Study In Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome Having Failed Conventional Therapy

Irritable Bowel Syndrome (IBS) | Irritable Colon

United States, Australia
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
AstraZeneca
Ironwood Pharmaceuticals, Inc.

Completed

A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) (D5630C00001)

Irritable Bowel Syndrome With Constipation (IBS-C)

United States, Australia, China, New Zealand, Canada
GlaxoSmithKline

Completed

Study Of Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome Having Failed Conventional Therapy

Irritable Bowel Syndrome (IBS) | Irritable Colon

United States, Australia
National Institute of Allergy and Infectious Diseases...

Completed

Plasmodium Resistance in A. Gambiae

Malaria | Plasmodium Falciparum Malaria

Burkina Faso
Medical University of South Carolina
Boston Scientific Corporation

Recruiting

Reduction of Myopotential Interference With Smart Pass in S-ICD Patients

Subcutaneous ICD | Myopotential Interference

United States
Ironwood Pharmaceuticals, Inc.
Allergan Sales, LLC

Completed

A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome With Diarrhea (IBS-D)

United States
GlaxoSmithKline
Novartis Vaccines

Completed

Safety and Immunogenicity of a Trivalent Group B Streptococcus Vaccine in Healthy Pregnant Women

Streptococcus Agalactiae | GBS Disease

United States
Institut Pasteur
Institut Pasteur de Bangui

Completed

Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum (MACOMBA)

HIV Infection | Malaria in Pregnancy

Central African Republic
Altman Biomedical Consulting Pty. Ltd.

Completed

Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application

Head Lice

Australia
Ohio State University Comprehensive Cancer Center

Recruiting

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer

United States, Canada
Epicentre
Drugs for Neglected Diseases; European and Developing Countries Clinical Trials... and other collaborators

Recruiting

Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan (PKDL)

Leishmaniasis | Leishmaniasis, Visceral | Post-kala-azar Dermal Leishmaniasis

South Sudan
University of Ghana
University of Rostock; Shai-Osudoku District Hospital; Kumasi Technical University and other collaborators

Active, not recruiting

Africa Ready Malaria Screening (ARMS)

Malaria

Ghana
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.

Malaria

Burkina Faso, Ghana, Kenya, Mali, Senegal, Zambia
Universiteit Antwerpen
Amref Health Africa

Completed

Effect of Onchocerciasis Elimination Measures on the Incidence of Epilepsy in Maridi, South Sudan (OAEMaridi)

Epilepsy | Onchocerciasis

South Sudan
Smith & Nephew, Inc.

Completed

S&P of Q-Fix™ All-Suture Anchor System

Bankart Lesion | Acetabular Labrum Tear | SLAP Lesion | Acromioclavicular Sprain | Capsular Shift/Capsulolabral Reconstruction | Deltoid Repair | Rotator Cuff Repair | Bicep Tendinitis | Extra-capsular Repair | Medial Collateral Ligament | Lateal Collateral Ligament | Posterior Oblique Ligament | IBT | Vastus Medialis and other conditions

United States
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa

Malaria, Falciparum

Burkina Faso, Kenya, Mali, Ghana, Côte D'Ivoire
Merck Sharp & Dohme LLC

Recruiting

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Malaria

Australia
Jhpiego
Centers for Disease Control and Prevention; Rwanda Malaria and Other Parasitic...

Completed

Routine Antenatal Care Versus Screening and Treatment of Malaria in Pregnancy in Rwanda

Malaria in Pregnancy

Rwanda
University of Yaounde 1
World Health Organization; Gates Malaria Partnership

Completed

Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon

Malaria

Cameroon
Universiteit Antwerpen
Amref Health Africa

Not yet recruiting

Onchocerciasis-Associated Epilepsy, an Explorative Case-control Study

Epilepsy | Virus | Onchocercal Subcutaneous Nodule

South Sudan
ParaPRO LLC

Completed

Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice

Pediculosis

United States
Dinka Dugassa
Ethiopian Public Health Institute

Completed

Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax (CQ+PQ)

Malaria | Efficacy | Vivax Malaria | Chloroquine

Ethiopia
Malaria Consortium

Active, not recruiting

Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan

Malaria

South Sudan

Clinical Trials on Parasite IBS IBD in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cameroon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations