Clinical Trials on Parasitic Disease

Total 381486 results

University of Oxford

Completed

Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria

Malaria

Bangladesh
National Institute of Allergy and Infectious Diseases...

Completed

Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children

Malaria

Mali
Malaria Vaccine and Drug Development Center
The Administrative Department of Science, Technology and Innovation, Colciencias

Completed

Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax

Malaria

Colombia
Malaria Vaccine and Drug Development Center
National Heart, Lung, and Blood Institute (NHLBI); Asoclinic Inmunología Ltda.

Completed

Immunization of Human Volunteers With P. Vivax Irradiated Sporozoites (SPZ-Irrad)

Malaria

Colombia
Centers for Disease Control and Prevention

Completed

Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil

Malaria

Brazil
Centro de Investigação em Saúde de Manhiça
Barcelona Institute for Global Health

Completed

Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique (MDAM)

Malaria
Ministry of Public Health, Democratic Republic...

Completed

Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo (TETRDC2016)

Malaria

Congo, The Democratic Republic of the
National Institute for Medical Research, Tanzania
World Health Organization; Ministry of Health and Social Welfare, Tanzania

Completed

In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure (WB-Malaria)

Malaria

Tanzania
Royal Tropical Institute

Completed

Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria (PAAL)

Malaria

Kenya
U.S. Army Medical Research and Development Command
GlaxoSmithKline; United States Agency for International Development (USAID); Walter... and other collaborators

Completed

Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults

Malaria

United States
Donald Krogstad
University of the Sciences, Techniques and Technologies of Bamako

Completed

Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)

Malaria

Mali
GlaxoSmithKline

Terminated

A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria

Malaria

Australia
U.S. Army Medical Research and Development Command
National Institute of Allergy and Infectious Diseases (NIAID); GlaxoSmithKline and other collaborators

Completed

Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali

Malaria

Mali
University of Oxford

Completed

A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313

Malaria

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Study of Factors Involved in Resistance to Severe Malaria

Malaria

United States
National Institute of Allergy and Infectious Diseases...

Completed

Experimental Vaccine for Malaria

Malaria

United States
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...

Malaria

United States
University of Oxford

Completed

A Study to Assess the Safety and Immunogenicity of a Malaria Vaccine Candidate, R21, Administered With AS01B

Malaria

United Kingdom
Makerere University
University of Michigan; Michigan State University

Completed

Computerized Cognitive Rehabilitation in Children After Severe Malaria (CM_CCRT)

Malaria

Uganda
GlaxoSmithKline

Completed

Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children

Malaria

Gabon
GlaxoSmithKline

Completed

Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension

Malaria

Japan
London School of Hygiene and Tropical Medicine
Medical Research Council

Completed

Comparison of Two Strategies for the Delivery of IPTc

Malaria

Gambia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B

Malaria

Australia
University Hospital, Basel, Switzerland

Completed

Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers (IVMPBPK)

Malaria

Switzerland
London School of Hygiene and Tropical Medicine
Department of State for Health and Social Welfare, The Gambia

Completed

Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children

Malaria

Gambia
London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia; Department of State for Health and...

Completed

Folic Acid Supplementation in Gambian Primigravidae

Malaria

Gambia
London School of Hygiene and Tropical Medicine
University of Oxford; Wellcome Trust; Medical Research Council Unit, The Gambia

Completed

Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-erythrocytic Candidate Malaria Vaccines

Malaria

Gambia
London School of Hygiene and Tropical Medicine
Cheikh Anta Diop University, Senegal; Institut de Recherche pour le Developpement and other collaborators

Completed

A Trial of Intermittent Treatment in the Prevention of Malaria in Senegalese Children

Malaria

Senegal
London School of Hygiene and Tropical Medicine
National Institute for Medical Research, Tanzania

Completed

A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania

Malaria

Tanzania
London School of Hygiene and Tropical Medicine
Medical Research Council; University of Oxford

Completed

Malaria Candidate Vaccines FP9 Circumsporozoite (CS) and MVA CS in Adult Gambian Men

Malaria

Gambia
London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia; Department of State for Health and...

Completed

Intermittent Preventative Treatment With Sulfadoxine-Pyrimethamine in Gambian Multigravidae

Malaria

Gambia
London School of Hygiene and Tropical Medicine
Kintampo Health Research Centre, Ghana

Completed

Kintampo Trial of Combination Therapy for Malaria

Malaria

Ghana
London School of Hygiene and Tropical Medicine
University of Copenhagen; National Institute for Medical Research, Tanzania; Kilimanjaro...

Completed

Kilimanjaro IPTi Drug Options Trial

Malaria

Tanzania
GlaxoSmithKline

Completed

Safety and Efficacy Dose of Artesunate Used in Combination With LAPDAP Treatment of Uncomplicated Falciparum Malaria

Malaria

Gambia, Malawi
Novartis Pharmaceuticals

Completed

A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection

Malaria

Vietnam
University of Minnesota

Completed

Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae

Malaria

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique.

Malaria

Mozambique
University of Oxford
Sanaria Inc.; KEMRI-Wellcome Trust Collaborative Research Program; University... and other collaborators

Unknown

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) (CHMI-SIKA)

Malaria

Kenya
Medecins Sans Frontieres, Netherlands

Completed

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo

Malaria
Lihir Medical Centre
Barcelona Institute for Global Health; Papua New Guinea Institute of Medical... and other collaborators

Completed

Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns (ECG-Lihir)

Malaria

Papua New Guinea
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Chemopreventive Therapy for Malaria in Ugandan Children (PROMOTE-Chemop)

Malaria

Uganda
Seattle Children's Research Institute (SCRI)

Completed

Safety, Attenuation and Immunogenicity of GAP3KO Administered Via A Stephensi Mosquitoes

Malaria

United States
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 (OZ/DSMCombo)

Malaria

Australia
Medicines for Malaria Venture
Queensland Institute of Medical Research

Completed

Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers

Malaria

Australia
IDinsight
National Malaria Control Centre, Zambia; Ministry of Health, Zambia; Clinton...

Completed

Community Point Distribution of Insecticide Treated Bed Nets

Malaria
Centre Muraz
Institute of Tropical Medicine, Belgium

Completed

Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso

Malaria

Burkina Faso
Centre Muraz
World Health Organization

Completed

ANC & Malaria Diagnostic in Pregnancy (AQUAMOD)

Malaria

Burkina Faso
Ministry of Health, Uganda
Columbia University; University of Copenhagen; LSHTM; Makerere University, College...

Unknown

Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda.

Malaria
Ottawa Hospital Research Institute

Unknown

Evaluating the Ottawa Malaria Decision Aid (OMDA)

Malaria

Canada

Clinical Trials on Parasitic Disease

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