Clinical Trials on Phosphodiesterase 5 Inhibitor

Total 686 results

Takeda

Completed

Safety and Pharmacokinetic Profile of Udenafil in Healthy Mexican Adults

Erectile Dysfunction | Phosphodiesterase 5 Inhibitor

Mexico
Rijnstate Hospital

Terminated

The Effects of Enoximone in Acute Exacerbation COPD

COPD Exacerbation | Enoximone | Phosphodiesterase Inhibitor

Netherlands
Vigonvita Life Sciences

Completed

A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects

Erectile Dysfunction | Alcohol | Phosphodiesterase Inhibitor

China
Mansoura University

Active, not recruiting

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Erectile Dysfunction Following Radiation Therapy | Phosphodiesterase Inhibitor Adverse Reaction | Platelet- Rich Plasma (PRP)

Egypt
University Hospital, Essen

Completed

Phosphodiesterase-5-inhibitors for Right Heart Failure After Left Ventricular Assist Device Implantation (PIVAD)

Right-Sided Heart Failure | Phosphodiesterase Inhibitor Adverse Reaction

Germany
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Long-term Tolerance of Proton Pump Inhibitor (PPI) Discontinuation in Geriatric Patients Treated With Long-term Therapy Without a Recognized Indication (EGERIPP 2)

Proton Pump Inhibitor

France
Catharina Ziekenhuis Eindhoven

Recruiting

Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT (THOMAS FU FLOT)

TDM of 5-FU | Pharmacokinetic Observational Study

Netherlands
Nanjing Medical University

Completed

Immune Checkpoint Inhibitors(ICPis)-Induced Endocrine Immune-related Adverse Events (irAEs)

Immune Checkpoint Inhibitor | Endocrine Toxicity

China
Marie Forgie
Aurora Health Care

Completed

Foley Catheter for Induction of Labor

Induction of Labor | Foley Catheterization | 5 French Stylette

United States
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of Rebound Effect After Withdrawal of Proton Pump Inhibitor in Geriatric Population

Proton Pump Inhibitor

France
Meir Medical Center

Unknown

Targeting ER-Golgi Homeostasis in an Advantageous Therapeutic Strategy in Lung Cancer

The Combined Effect of Hsp90 Inhibitor and HDAC/Proteasome Inhibitors on Lung Cancer Cell Fate and ER-Golgi Homeostasis Will be Examined.

Israel
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer (RADIOCOM)

Chemotherapeutic Toxicity | Radiotherapy; Complications | PARP Inhibitor | Immune Checkpoint Inhibitor | Trastuzumab | Breast Cancer, Familial Male | CDK4/6 Inhibitor | Pertuzumab

China
California Institute of Renal Research

Recruiting

A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)

CKD Stage 4 | CKD Stage 5 | CKD Stage 3

United States
McGill University Health Centre/Research Institute...

Recruiting

Safety and Efficacy of Canagliflozin in Advanced CKD (SIP-AKiD)

ESRD | CKD Stage 4 | CKD Stage 5

Canada
Tanta University

Completed

Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery

Dexmedetomidine | Arthroscopic Knee Surgery | Lidocaine 5% Patch | Intra-articular
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Treatment for Caffeine Dependence

Caffeine Use Disorder (DSM-5 Condition for Further Study)

United States
Sun Yat-sen University

Recruiting

Safety and Efficacy of RX-af01 Combined With PD-1 Antibody

Solid Tumor | Intestinal Flora | Immune Checkpoint Inhibitor

China
Teesside University
University of Sunderland

Recruiting

The Effect of 6 Weeks Jump Training on Sand Versus Hard Surfaces on Jump Landing and Performance in Young Females

Frontal Plane Projection Angle | Maximal Countermovement Jump | Repeated 10/5

United Kingdom
University of Talca
Universidad de los Andes, Chile

Not yet recruiting

Early Development of Academic Skills in the Classroom (JAPI)

General Population of Children Aged 3 to 5 Years Old
University of Kansas Medical Center

Recruiting

Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users

HMG-CoA Reductase Inhibitor Toxicity

United States
Mario Negri Institute for Pharmacological Research
Federico II University; IRCCS Multimedica

Completed

Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly (LAPTOP-PPI)

Proton Pump Inhibitor | Primary Care

Italy
American Thrombosis and Hemostasis Network
Takeda; CSL Behring; Octapharma

Completed

ATHN 8: Previously Untreated Patients (PUPs) Matter Study

Hemophilia A | Hemophilia B | Hemophilia | Hemophilia A With Inhibitor | Haemophilia | Hemophilia B With Inhibitor | Haemophilia A Without Inhibitor | Haemophilia B Without Inhibitor

United States
VA Office of Research and Development
VHA Pharmacy Benefits Management Services VA Center For Medication Safety

Completed

Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program (RaPPID)

Proton Pump Inhibitors

United States
Groupe Hospitalier Pitie-Salpetriere
Vanderbilt University Medical Center

Completed

Identification of PAthways of Kinase Inhibitors TOxicity (PAKITO)

Kinase Inhibitors Toxicity

France
Ospedale Santa Croce-Carle Cuneo

Unknown

Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)

Platelet Aggregation Inhibitors
Institut Mutualiste Montsouris
Institut Curie

Recruiting

Troponin to Detect Major Cardiovasculaire Advserse Events on Immune Checkpoint Inhibitors (TILT)

Cancer | Immune Checkpoint Inhibitor | Cardiovascular Biomarkers

France
Taichung Veterans General Hospital

Recruiting

Efficacy and Toxicity of SCART

Tumor Size Greater Than or Equal to 5 cm

Taiwan
Radboud University Medical Center

Completed

Patient Journey Application for Discontinuing Inappropriate PPI Use: a Randomized Controlled Trial (SUPPORT)

Proton Pump Inhibitor | Inappropriate Drug Use | Discontinuation | E-health

Netherlands
Assiut University

Unknown

Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test

Proton Pump Inhibitor Allergy
Assiut University

Unknown

Effect of Daily Use Proton Pump Inhibitors for One Month on Kidney Function

Proton Pump Inhibitor Allergy
Heinrich-Heine University, Duesseldorf

Recruiting

Vaccination Against COVID-19 in Chronic Kidney Disease

Vaccine Response Impaired | Chronic Kidney Disease Stage 5 on Dialysis | Chronic Kidney Disease Stage 5 With Transplant

Germany
Bursa Postgraduate Hospital

Completed

The Effect of Contrast Agents on the Anticoagulant Properties of Oral Factor Xa Inhibitors

Contrast Agents and Oral Factor Xa Inhibitor

Turkey
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial. (DeprescrIPP)

Proton Pump Inhibitors | Deprescription

France
Institut Mutualiste Montsouris

Recruiting

Fast-Track Cardiovascular Assessment for Suspicion of Cardiovascular Events on Immunecheckpoint Inhibitors (FAST-TRACK)

Cancer | Cardiovascular Complication | Immune Checkpoint Inhibitor | Immune-related Adverse Event

France
Sohag University

Not yet recruiting

Unintended Home Injuries in Under-5 Children in Sohag Governorate

Unintended Home Injuries in Under-5 Children
Medicure

Recruiting

Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency (MEND-PNPO)

Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency

United States, Australia
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Carotid Artery Plaque | Plaque, Atherosclerotic | Immune Checkpoint Inhibitors | Programmed Cell Death Protein 1 Inhibitor | Intimal Medial Thickness of Internal Carotid Artery

China
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention Combining an Educational Outreach Visit to General Practitioners and Patient Education Material to Deprescribe Proton Pump Inhibitors (PPI): a Population-based, Pragmatic, Cluster-randomized Controlled Trial (DeprescrIPPDAM)

Proton Pump Inhibitors | Deprescription

France
Drexel University

Completed

Training Response Inhibition to Obesogenic Foods

Inhibitory Control Training | Gameifaction

United States
American Thrombosis and Hemostasis Network
Genentech, Inc.

Active, not recruiting

ATHN 7: Hemophilia Natural History Study (ATHN 7)

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Haemophilia A Without Inhibitor | Haemophilia B Without Inhibitor

United States
Catalyst Biosciences

Completed

Study of Coagulation Faction VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia

Hemophilia A | Hemophilia B | Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Hemophilia A Without Inhibitor | Hemophilia B Without Inhibitor

Bulgaria, Russian Federation
Lee's Pharmaceutical Limited

Not yet recruiting

Phase III Clinical Trial Evaluating the Efficacy and Safety of 5-aminolevulinic Acid (5-ALA）

5-aminolevulinic Acid | Fluorescence-guided Resection

China
Alere San Diego

Completed

Alere Triage fs B-type Natriuretic Peptide (BNP) Method Comparison Evaluation (ABC)

Triage | Specimens With BNP Values of 5 to 5000 pg/ml
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer

Malignant Tumor | Positron Emission Tomography | Fibroblast Activation Protein Inhibitor

China
Hellenic Cooperative Oncology Group

Completed

Checkpoint Inhibitors in Patients With Cancer and Underlying Autoimmune Disease (CIAD)

Autoimmune Diseases | Immunotherapy | Checkpoint Inhibitor

Greece
Ronald Buckanovich
Genentech, Inc.

Recruiting

Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

PARP Inhibitor | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Hedgehog Inhibitor

United States
Zhongnan Hospital

Recruiting

68Ga-FAPI PET/CT in Malignant Tumors

Malignant Neoplasm | PET/CT | Fibroblast Activation Protein Inhibitor

China
Northumbria University
Plant & food Research Ltd

Completed

Pharmacodynamic Profile of 'Blackadder' Blackcurrant Juice Effects Upon the Monoamine Axis in Humans

Monoamine Oxidase Inhibitor Activity | Prolactin Levels | Postprandial Blood Glucose
Hospital Comarcal de Inca

Completed

Inappropriate Prescription in Elderly and Polypharmacy Patients in Primary Care (PHARM-PC) Trial (PHARM-PC)

Elderly (People Aged 65 or More) | Polypharmacy (People Under Treatment With 5 or More Drugs)

Spain
Universidad Vina del Mar

Completed

Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women

Contraceptive Usage | Diffuse Noxious Inhibitory Control

Chile

Clinical Trials on Phosphodiesterase 5 Inhibitor

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