Clinical Trials on Phosphodiesterase Inhibitor

Total 523 results

Rijnstate Hospital

Terminated

The Effects of Enoximone in Acute Exacerbation COPD

COPD Exacerbation | Enoximone | Phosphodiesterase Inhibitor

Netherlands
Takeda

Completed

Safety and Pharmacokinetic Profile of Udenafil in Healthy Mexican Adults

Erectile Dysfunction | Phosphodiesterase 5 Inhibitor

Mexico
Vigonvita Life Sciences

Completed

A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects

Erectile Dysfunction | Alcohol | Phosphodiesterase Inhibitor

China
Mansoura University

Active, not recruiting

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Erectile Dysfunction Following Radiation Therapy | Phosphodiesterase Inhibitor Adverse Reaction | Platelet- Rich Plasma (PRP)

Egypt
University Hospital, Essen

Completed

Phosphodiesterase-5-inhibitors for Right Heart Failure After Left Ventricular Assist Device Implantation (PIVAD)

Right-Sided Heart Failure | Phosphodiesterase Inhibitor Adverse Reaction

Germany
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of the Long-term Tolerance of Proton Pump Inhibitor (PPI) Discontinuation in Geriatric Patients Treated With Long-term Therapy Without a Recognized Indication (EGERIPP 2)

Proton Pump Inhibitor

France
Nanjing Medical University

Completed

Immune Checkpoint Inhibitors(ICPis)-Induced Endocrine Immune-related Adverse Events (irAEs)

Immune Checkpoint Inhibitor | Endocrine Toxicity

China
Groupe Hospitalier Paris Saint Joseph

Completed

Evaluation of Rebound Effect After Withdrawal of Proton Pump Inhibitor in Geriatric Population

Proton Pump Inhibitor

France
Meir Medical Center

Unknown

Targeting ER-Golgi Homeostasis in an Advantageous Therapeutic Strategy in Lung Cancer

The Combined Effect of Hsp90 Inhibitor and HDAC/Proteasome Inhibitors on Lung Cancer Cell Fate and ER-Golgi Homeostasis Will be Examined.

Israel
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer (RADIOCOM)

Chemotherapeutic Toxicity | Radiotherapy; Complications | PARP Inhibitor | Immune Checkpoint Inhibitor | Trastuzumab | Breast Cancer, Familial Male | CDK4/6 Inhibitor | Pertuzumab

China
Sun Yat-sen University

Recruiting

Safety and Efficacy of RX-af01 Combined With PD-1 Antibody

Solid Tumor | Intestinal Flora | Immune Checkpoint Inhibitor

China
University of Kansas Medical Center

Recruiting

Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users

HMG-CoA Reductase Inhibitor Toxicity

United States
Mario Negri Institute for Pharmacological Research
Federico II University; IRCCS Multimedica

Completed

Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly (LAPTOP-PPI)

Proton Pump Inhibitor | Primary Care

Italy
American Thrombosis and Hemostasis Network
Takeda; CSL Behring; Octapharma

Completed

ATHN 8: Previously Untreated Patients (PUPs) Matter Study

Hemophilia A | Hemophilia B | Hemophilia | Hemophilia A With Inhibitor | Haemophilia | Hemophilia B With Inhibitor | Haemophilia A Without Inhibitor | Haemophilia B Without Inhibitor

United States
VA Office of Research and Development
VHA Pharmacy Benefits Management Services VA Center For Medication Safety

Completed

Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program (RaPPID)

Proton Pump Inhibitors

United States
Groupe Hospitalier Pitie-Salpetriere
Vanderbilt University Medical Center

Completed

Identification of PAthways of Kinase Inhibitors TOxicity (PAKITO)

Kinase Inhibitors Toxicity

France
Ospedale Santa Croce-Carle Cuneo

Unknown

Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)

Platelet Aggregation Inhibitors
Institut Mutualiste Montsouris
Institut Curie

Recruiting

Troponin to Detect Major Cardiovasculaire Advserse Events on Immune Checkpoint Inhibitors (TILT)

Cancer | Immune Checkpoint Inhibitor | Cardiovascular Biomarkers

France
Radboud University Medical Center

Completed

Patient Journey Application for Discontinuing Inappropriate PPI Use: a Randomized Controlled Trial (SUPPORT)

Proton Pump Inhibitor | Inappropriate Drug Use | Discontinuation | E-health

Netherlands
Assiut University

Unknown

Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test

Proton Pump Inhibitor Allergy
Assiut University

Unknown

Effect of Daily Use Proton Pump Inhibitors for One Month on Kidney Function

Proton Pump Inhibitor Allergy
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial. (DeprescrIPP)

Proton Pump Inhibitors | Deprescription

France
Bursa Postgraduate Hospital

Completed

The Effect of Contrast Agents on the Anticoagulant Properties of Oral Factor Xa Inhibitors

Contrast Agents and Oral Factor Xa Inhibitor

Turkey
Institut Mutualiste Montsouris

Recruiting

Fast-Track Cardiovascular Assessment for Suspicion of Cardiovascular Events on Immunecheckpoint Inhibitors (FAST-TRACK)

Cancer | Cardiovascular Complication | Immune Checkpoint Inhibitor | Immune-related Adverse Event

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Carotid Artery Plaque | Plaque, Atherosclerotic | Immune Checkpoint Inhibitors | Programmed Cell Death Protein 1 Inhibitor | Intimal Medial Thickness of Internal Carotid Artery

China
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention Combining an Educational Outreach Visit to General Practitioners and Patient Education Material to Deprescribe Proton Pump Inhibitors (PPI): a Population-based, Pragmatic, Cluster-randomized Controlled Trial (DeprescrIPPDAM)

Proton Pump Inhibitors | Deprescription

France
Drexel University

Completed

Training Response Inhibition to Obesogenic Foods

Inhibitory Control Training | Gameifaction

United States
American Thrombosis and Hemostasis Network
Genentech, Inc.

Active, not recruiting

ATHN 7: Hemophilia Natural History Study (ATHN 7)

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Haemophilia A Without Inhibitor | Haemophilia B Without Inhibitor

United States
Catalyst Biosciences

Completed

Study of Coagulation Faction VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia

Hemophilia A | Hemophilia B | Hemophilia A With Inhibitor | Hemophilia B With Inhibitor | Hemophilia A Without Inhibitor | Hemophilia B Without Inhibitor

Bulgaria, Russian Federation
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer

Malignant Tumor | Positron Emission Tomography | Fibroblast Activation Protein Inhibitor

China
Hellenic Cooperative Oncology Group

Completed

Checkpoint Inhibitors in Patients With Cancer and Underlying Autoimmune Disease (CIAD)

Autoimmune Diseases | Immunotherapy | Checkpoint Inhibitor

Greece
Ronald Buckanovich
Genentech, Inc.

Recruiting

Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

PARP Inhibitor | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Hedgehog Inhibitor

United States
Zhongnan Hospital

Recruiting

68Ga-FAPI PET/CT in Malignant Tumors

Malignant Neoplasm | PET/CT | Fibroblast Activation Protein Inhibitor

China
Northumbria University
Plant & food Research Ltd

Completed

Pharmacodynamic Profile of 'Blackadder' Blackcurrant Juice Effects Upon the Monoamine Axis in Humans

Monoamine Oxidase Inhibitor Activity | Prolactin Levels | Postprandial Blood Glucose
Universidad Vina del Mar

Completed

Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women

Contraceptive Usage | Diffuse Noxious Inhibitory Control

Chile
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Investigation of Potential Retinal Toxicity Associated With Hair Dye Products Containing pPD Type Aromatic Amines (CAPITOX)

MEK Inhibitor-Associated Serous Retinopathy

France
Samsung Medical Center

Suspended

Aromatase (CYP19) Polymorphism Between AI-responsive and AI-resistant Breast Cancer in Korea (CYP19)

Polymorphism | CYP19 | Aromatase Inhibitor

Korea, Republic of
Samsung Medical Center

Completed

The Compliance of DAPT and Statins on Clinical Outcomes in Percutaneous Coronary Intervention Patients (CPPCI)

Adherence, Medication | Percutaneous Coronary Intervention | Compliance, Medication | Platelet Aggregation Inhibitors | Hydroxymethylglutaryl-coa Reductase Inhibitors | Persistence, Medication

Korea, Republic of
Atsushi Kawakami
Gilead Sciences

Recruiting

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate (TRANSFORM)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound | IL-6 Inhibitor

Japan
Duke University

Completed

GM03 - Platelet RNA Signatures of Aspirin

Aspirin | Platelet Aggregation Inhibitors | Ticagrelor | RNA

United States
Radboud University Medical Center

Completed

Exercise-induced Muscle Damage in Statin Users

Cardiovascular Diseases | Muscle Damage | HMG COA Reductase Inhibitor Adverse Reaction

Netherlands
Ege University

Completed

Effect of Caffeic Acid Phenethyl Ester as a Matrix Metalloproteinase Inhibitor: Randomized Controlled Clinical Trial

Composite Resins | Matrix Metalloproteinase Inhibitors
Sun Yat-sen University

Unknown

Single Dose of Atorvastatin and Circulating Endothelial Microparticles

Hydroxymethylglutaryl-CoA Reductase Inhibitors | Endothelium
Institut Curie

Recruiting

Development of an EORTC Immune Checkpoint Inhibitor-specific Quality of Life Item List: Phase 1 & 2 (EORTC ICI)

Quality of Life | Cancer | IMMUNE CHECKPOINT INHIBITOR

France
Dr Abdurrahman Yurtaslan Ankara Oncology Training...

Completed

Is Long-Term Proton Pump Inhibitor Use a Cause of Leaky Gut Syndrome

Proton Pump Inhibitor Adverse Reaction

Turkey
Sun Yat-sen University

Recruiting

PD-1 Inhibitor Plus G-CSF in Recurrent/Metastatic NPC With First-line Treatment Failure

PD-1 Inhibitor | G-CSF

China
Medical University of Graz

Completed

Probiotic Modulation of Intestinal Microbiota in Long-term Intake of Proton Pump Inhibitors

Patients on Long-term Proton Pump Inhibitor Therapy

Austria
Bayer

Completed

Ovulation Inhibition of Two 4-phasic Oral Contraceptive Regimens

Ovulation Inhibition

Germany, Netherlands
AstraZeneca
POZEN

Completed

A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin

Platelet Inhibition

United States
Pharvaris Netherlands B.V.

Recruiting

Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema (RAPIDe-3)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States

Clinical Trials on Phosphodiesterase Inhibitor

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