Clinical Trials on Phosphorus Metabolism Disorders

Total 214 results

UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy ...

United Kingdom
Inozyme Pharma

Recruiting

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency

United States
University of Tartu

Not yet recruiting

Validation of the GIDS and Description of Phosphate Disorders (GUTPHOS)

Hypophosphatemia | Organ Dysfunction Scores
Liu, Liu-Yin

Recruiting

Explore the Effectors of The Transtheoretical Model on Nutritional Education in Patients on Hemodialysis

End-Stage Kidney Disease | Hyperphosphatemia

Taiwan
Alebund Pharmaceuticals

Recruiting

A Study to Evaluate Safety and Efficacy of AP-306 in Hyperphosphatemia Patients

Chronic Kidney Diseases | Hyperphosphatemia

China
Inozyme Pharma

Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency (ENERGY)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency

United States
Taisho Pharmaceutical Co., Ltd.

Recruiting

A Phase 2 Dose-finding Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis

Hyperphosphatemia Patients on Hemodialysis

Japan
Centre Hospitalier Régional de la Citadelle

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease ...

Belgium
Assiut University

Not yet recruiting

av Fistula Patency Loss as a Cause of Fistula Failure and Hyperphosphatemia

AV Fistula

Egypt
National Institute of Dental and Craniofacial Rese...

Recruiting

Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia

Fibrous Dysplasia Of Bone

United States
Great Ormond Street Hospital for Children NHS Foun...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Kyowa Kirin Pharmaceutical Development Ltd

Recruiting

A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth

X-Linked Hypophosphatemia

France, Netherlands, United Kingdom
Inozyme Pharma

Not yet recruiting

Natural History Study of ENPP1 Deficiency and and the Early-onset Form of ABCC6 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | ATP-Binding Cassette Subfamily C Member 6 Deficiency
Wuerzburg University Hospital

Recruiting

Burden of Disease and Functional Impairment in XLH (IdeFIX)

X Linked Hypophosphatemia

Germany
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT (PRADEX)

X-linked Hypophosphatemia (XLH)
Hospices Civils de Lyon

Recruiting

Hypophosphatemia and Bronchiolitis

Bronchiolitis | Hypophosphatemia

France
Inozyme Pharma

Recruiting

Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ENPP1 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency

United States, United Kingdom, Canada, France, Germany
Keryx Biopharmaceuticals

Recruiting

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

Hyperphosphatemia Related to Chronic Kidney Disease

United States
Grand Life Science (Liaoning) Co., Ltd.

Recruiting

To Evaluate the Patient Tolerance, Pharmacodynamics and Pharmacokinetics of Lanthanum Polystyrene Sulfonate Powder

Hyperphosphatemia

China
Duke University

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children ...

United States, Canada
University of Aarhus

Recruiting

Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls

X-linked Hypophosphatemia | Hereditary Hypophosphatemia

Denmark
Assistance Publique - Hôpitaux de Paris

Recruiting

Dental Implants in Patients With X-linked Hypophosphatemia (IMPLANTS-XLH)

X-linked Hypophosphatemia

France
Massachusetts General Hospital

Recruiting

Calcitriol Monotherapy for X-Linked Hypophosphatemia

X-linked Hypophosphatemia | Hypophosphatemic Rickets | Hypophosphatemic Rickets, X-Linked Dominant

United States
The University of Queensland

Recruiting

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE) (PHOSPHATE)

Kidney Failure, Chronic | Hyperphosphatemia

Canada, United Kingdom, Australia, Brazil, New Zealand
Kyowa Kirin Pharmaceutical Development Ltd

Active, not recruiting

Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age

X-linked Hypophosphatemia (XLH)

Sweden, Spain, United Kingdom, Italy, Austria, France
Ultragenyx Pharmaceutical Inc

Active, not recruiting

X-linked Hypophosphatemia Disease Monitoring Program

X-linked Hypophosphatemia | Hypophosphatemic Rickets

United States, Brazil, Argentina, Canada, Chile, Colombia
National Human Genome Research Institute (NHGRI)

Completed

Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets Type2

United States
Winthrop University Hospital

Terminated

Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol (ECRIP)

Secondary Hyperparathyroidism | Kidney Failure | Hyperphosphatemia | Hypercalcemia

United States
University of Zurich

Active, not recruiting

Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia

Hypophosphatemia

Switzerland
University Hospital, Geneva

Completed

Newborn Phosphocalcic Metabolism After Intravenous Iron Administration During Pregnancy

Iron Induced Hypophosphatemia

Switzerland
USRC Kidney Research

Active, not recruiting

Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease (FRONTIER)

Disease Progression | Renal Insufficiency, Chronic | Hyperphosphatemia | Anemia, Iron Deficiency | Renal Anemia | Iron | Cardiovascular

United States
Medialis Ltd.

Completed

Retrospective and Prospective Disease Progression and Quality of Life in XLH

X-linked Hypophosphatemia (XLH)

United Kingdom
Orthopedic Hospital Vienna Speising

Completed

Foot Disorders in X-linked Hypophosphatemia

X-linked Hypophosphatemia

Austria
Hospital Universitari de Bellvitge

Active, not recruiting

mHealth for Phosphorus Management in CKD. (PHOSFO_OK)

Dialysis Related Complication

Spain
Ultragenyx Pharmaceutical Inc

Available

Expanded Access to Burosumab

X-linked Hypophosphatemia | Tumor-Induced Osteomalacia
Yale University

Completed

Examining the Effect of Burosumab on Muscle Function

X-linked Hypophosphatemia

United States
Kyowa Kirin Co., Ltd.

Active, not recruiting

Study of Longitudinal Observation for Patient With X-linked Hypophosphatemic Rickets/Osteomalacia in Collaboration With Asian Partners (SUNFLOWER)

X-Linked Hypophosphatemia

Japan
Kyowa Kirin Co., Ltd.

Completed

Phosphate Binder Switch Study of KHK7791 in Hyperphosphatemia Patients on Hemodialysis

Hyperphosphatemia

Japan
Ardelyx

Completed

A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis

Hyperphosphatemia

United States
Kyowa Kirin Pharmaceutical Development Ltd

Completed

A UK Multicentre, Health-Related Quality of Life Study for Children and Adolescents With XLH

X-Linked Hypophosphataemia

United Kingdom
Donat R. Spahn

Completed

Ferric Carboxymaltose With or Without Phosphate Substitution for the Treatment of Iron Deficiency or Iron Deficiency Anemia

Iron-deficiency | Anemia | Hypophosphatemia

Switzerland
Medical University of Warsaw

Completed

The Effect of Bicarbonate Profiling in Dialysis Fluid on Phosphate Removal During Hemodialysis and Blood pH

Phosphorus Metabolism Disorders | Acid-Base Balance Disorder

Poland
University Hospital, Clermont-Ferrand

Completed

Study of the Inappropriate Secretion of FGF23 in Patients Followed in Hospital in a Context of Hypophosphatemia (IFEH)

Hypophosphatemia Without Immediate Anteriority | Unexplained Hypophosphatemia

France
Wuerzburg University Hospital

Completed

Anti-FGF23 (Burosumab) in Adult Patients With XLH (BurGER)

X-linked Hypophosphatemia

Germany
Kyowa Kirin, Inc.

Completed

Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Kyowa Kirin, Inc.

Completed

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Kyowa Kirin, Inc.

Completed

Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

United States, Korea, Republic of, Canada, Japan, France, Denmark
Kyowa Kirin, Inc.

Completed

Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

United States, Korea, Republic of, Japan, Ireland, United Kingdom, France, Italy
Kyowa Kirin, Inc.

Completed

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

Netherlands, United States, United Kingdom, France
Kyowa Kirin, Inc.

Completed

Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

Korea, Republic of, Canada, United States, Australia, Japan, United Kingdom, Sweden

Clinical Trials on Phosphorus Metabolism Disorders

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CROs in Congo, DR of

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