Clinical Trials on Pleomorphic Xanthoastrocytoma of Brain

Total 1806 results

Istari Oncology, Inc.
Duke University; Solving Kids' Cancer; The Andrew McDonough B+ Foundation

Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Glioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of Brain

United States
National Cancer Institute (NCI)

Recruiting

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | WHO Grade 3 Glioma

United States, Puerto Rico
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Pfizer

Terminated

Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG (BRAF)

Glioblastoma | High Grade Glioma | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Pleomorphic Xanthoastrocytoma | BRAF V600E | BRAF V600K

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditions

United States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
Wake Forest University Health Sciences

Completed

Social Determinants of Health in Glioblastoma Population

Glioma | Astrocytoma | Ependymoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Oligodendroglioma

United States
University Hospital, Strasbourg, France

Recruiting

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

Pleomorphic Xanthoastrocytoma | Grade 1 Glioma | Mixed Glio-neuronal Tumors

France
Mansoura University

Withdrawn

Quadrant Versus Superficial Parotidectomy

Pleomorphic Adenoma of the Parotid Gland

Egypt
St. Jude Children's Research Hospital

Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Glioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid Astrocytoma

United States
Stanford University

Not yet recruiting

Identification of Nerves Using Fluorescein Sodium

Head and Neck Disorder | Warthin Tumor | Pleomorphic Adenoma of the Parotid

United States
Amina Fouad Farag

Completed

Diagnostic and Prognostic Accuracy of Gold Nanoparticles in Salivary Gland Tumours

Carcinoma Ex Pleomorphic Adenoma of Salivary Glands | Pleomorphic Adenoma of Salivary Glands

Egypt
Chimerix
National Institutes of Health (NIH)

Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Glioblastoma | Neuroectodermal Tumors | Neuroectodermal Tumors, Primitive | Central Nervous System Neoplasms | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Pleomorphic Xanthoastrocytoma | Pleomorphic Xanthoastrocytoma | Oligodendroglioma | Choroid Plexus Neoplasms | Diffuse Astrocytoma | Anaplastic... and other conditions

United States
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Sintilimab for the Treatment of Locally Advanced, Metastatic, Recurrent, or Unresectable Undifferentiated Pleomorphic Sarcoma, SiARa Cancer Study

Metastatic Undifferentiated Pleomorphic Sarcoma | Recurrent Undifferentiated Pleomorphic Sarcoma | Locally Advanced Undifferentiated Pleomorphic Sarcoma | Unresectable Undifferentiated Pleomorphic Sarcoma

United States
Julie Krystal
Janssen Pharmaceuticals

Recruiting

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Pleomorphic Xanthoastrocytoma | Pilocytic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Low-grade Glioma | DIPG | Brainstem Glioma | Optic Nerve Glioma | Pilomyxoid Astrocytoma | Glioma, Astrocytic

United States
St. Jude Children's Research Hospital
Novartis Pharmaceuticals

Completed

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Glioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditions

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); Highlight Therapeutics

Active, not recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Undifferentiated High Grade Pleomorphic Sarcoma of Bone | Myxofibrosarcoma | Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery

Undifferentiated Pleomorphic Sarcoma | Recurrent Undifferentiated Pleomorphic Sarcoma | Dedifferentiated Liposarcoma | Resectable Dedifferentiated Liposarcoma | Resectable Undifferentiated Pleomorphic Sarcoma | Recurrent Dedifferentiated Liposarcoma

United States
Federal University of Minas Gerais
Santa Casa de Misericórdia de Belo Horizonte

Completed

Sedation to Electroencephalography With Dexmedetomidine or Chloral Hydrate

Other Conditions of Brain

Brazil
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
University Hospital of Patras

Completed

Comparison of Parameters Between a Frameless Brain Biopsy Method and the Standard Frame-based Stereotactic Biopsy

Lesion of Brain
Johns Hopkins University
National Institute on Aging (NIA)

Terminated

PET Imaging of Extrathalamic α4β2-nicotinic Acetylcholine Receptors in Health and Disease With [18F]XTRA

Measure of Uptake of XTRA in the Brain

United States
Vanderbilt University

Completed

Brain Retraction Monitoring Sensor Study

Brain Surgery Requiring Significant Retraction of the Brain

United States
Virginia Commonwealth University

Completed

Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures

Identify the Presence of a Marker of Ischemia/Hypoperfusion of the Brain Via Peripheral Blood | Ischemia/Hypoperfusion of Brain

United States
Seoul National University Hospital

Completed

Impact of Celecoxib on Electrophysiological Property in Brain of Healthy Volunteer

Electrophysiologic Property of Brain

Korea, Republic of
Indiana University

Recruiting

Intervention to Change Affect Recognition and Empathy (ICARE)

Traumatic Brain Injury | Concussion, Severe | Concussion, Intermediate | Concussion With Brief Loss of Consciousness | Traumatic Brain Injury With Brief Loss of Consciousness | Traumatic Brain Injury With No Loss of Consciousness | Concussion With LOC 31 to 59 Minutes | Traumatic Brain Injury With... and other conditions

United States
Hull University Teaching Hospitals NHS Trust
University of Bath

Completed

Exercise Study in Brain and CNS Cancer (ESIBAC)

Cancer of Brain and Nervous System

United Kingdom
Rennes University Hospital

Completed

PERINE : Effect of Prenatal Exposure to Neurotoxicants on the Developing Brain : an MRI Study (PERINE)

Effects of Neurotoxicants on the Brain

France
University of Florida

Completed

1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients

Brain Neoplasms | Brain Cancer | Brain Tumors | Seizure | Cancer of the Brain | Cancer of Brain

United States
Hospices Civils de Lyon

Suspended

Boosting Reward-based Attention Through VEstibular STimulation (BRAVEST)

Brain Lesion of the Right Hemisphere | Unilateral Spatial Neglect for Half of Them

France
Sue O'Dorisio
National Cancer Institute (NCI); Ride for Kids

Withdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Untreated Childhood Brain Stem Glioma | Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma and other conditions

United States
AbbVie

Completed

ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors

Advanced Solid Tumors | Squamous Cell Carcinoma of the Head and Neck | Undifferentiated Pleomorphic Sarcoma | Carcinoma of the Breast

United States, France, Spain
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Brooke Army Medical Center
Henry M. Jackson Foundation for the Advancement of Military Medicine; The Defense...

Completed

The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury (SCORE)

Traumatic Brain Injury With Brief Loss of Consciousness | Traumatic Brain Injury With No Loss of Consciousness

United States
Seoul National University Hospital

Completed

Low-Intensity Focused Ultrasound on Individuals With Disorder of Consciousness of Traumatic Brain Injury

Traumatic Brain Injury With Prolonged Loss of Consciousness

Korea, Republic of
Johns Hopkins University
National Institute of Mental Health (NIMH)

Recruiting

Cerebellar Involvement in Cognitive Sequencing

Effects of Cerebellar Stimulation on Brain Activation

United States
Tetra Discovery Partners

Withdrawn

A Phase 1, Open-Label, PET Study of T2310 & BPN14770

To Determine Brain Target Occupancy of BPN14770

United States
Clionsky Neuro Systems Inc.

Completed

Concussion in Motor Vehicle Accidents: The Concussion Identification Index (CIDI)

Brain Injuries | TBI (Traumatic Brain Injury) | Motor Vehicle Accidents | Brain Concussion | Brain Contusion | Traumatic Brain Injury With Brief Loss of Consciousness | Cerebral Concussion | Accidents, Traffic | Traumatic Brain Injury With Loss of Consciousness | Traffic Accidents | Cortical Contusion | Concussion... and other conditions

United States
Stony Brook University

Recruiting

SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury

Traumatic Brain Injury | Disorder of Consciousness | Acute Brain Injury | Trauma, Brain | Consciousness, Loss of

United States
Asan Medical Center
Olympus

Completed

Validation of 3 Dimensional Laparoscopic System in Disral Pancreatectomy and Splenectomy

Benign Neoplasm of Body of Pancreas | Benign Neoplasm of Tail of Pancreas
Oded Meiron
Neurosteer Ltd.

Completed

Excitatory Prefrontal Weak Current Stimulation in Vegetative Patients (VEG-TDCS)

Disorder of Consciousness | Trauma, Brain | Vegetative State | MMN | Modification of Cognitive Status Indication | Anoxic Brain Damage | EEG; Paroxysms, Occipital, Epilepsy of Childhood | Cortical Atrophy

Israel
M.D. Anderson Cancer Center

Completed

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

Brain Tumor | Malignant Neoplasm of Fourth Ventricle of Brain

United States
University of Florida

Completed

Out-of-hospital Cardiac Arrest (OHCA) Biomarkers

Brain Injuries | Cardiac Arrest | Hypoxia, Brain | Hypoxia-Ischemia, Brain | Out-Of-Hospital Cardiac Arrest | Cardiac Arrest With Successful Resuscitation | Cardiac Arrest, Out-Of-Hospital | Neurological Outcome | Brain Anoxia Ischemia

United States
University of Manitoba

Terminated

Investigating Transcranial Alternating Current Stimulation (tACS) Preconditioning Effects on Resting and Active Motor Threshold

Understand the Effects of tACS on the Brain

Canada
University of Manchester

Suspended

The Effects of Cerebellar rTMS on Brain Activity

The Effects of Cerebellar rTMS on the Brain

United Kingdom
The University of Texas Health Science Center,...

Completed

Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors

Malignant Neoplasm of Fourth Ventricle of Brain | Brain Tumor, Recurrent

United States
General Hospital of Ningxia Medical University

Unknown

The Clinical Research on the Relationship Between Circadian Rhythm and Gut Microbiota in TBI Patients

Traumatic Brain Injury | Loss of Consciousness of Unspecified Duration | Cerebral Laceration and Contusion

China
University of Regensburg

Completed

Shortening of the Twitch Stabilization Period by Tetanic Stimulation in Acceleromyography in Children and Young Adults (STSTS)

Train-of-Four-Monitoring

Germany
Duke University
National Institutes of Health (NIH)

Completed

Memory and Picture Viewing Study (MPVS)

Healthy | Brain Reactivity of Non-smokers Undergoing fMRI Scanning

United States
University of Florida

Completed

Outcomes Study of Late Effects After Proton RT for Pediatric Tumors of the Brain, Head, and Neck (CN01)

Central Nervous System Tumors

United States
Case Comprehensive Cancer Center

Completed

18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis

Secondary Malignant Neoplasm of Brain and Cerebral Meninges

United States

Clinical Trials on Pleomorphic Xanthoastrocytoma of Brain

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