Clinical Trials on Pontine Tumors

Total 17136 results

Crystal Mackall, MD
National Institutes of Health (NIH); California Institute for Regenerative... and other collaborators

Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Glioma of Spinal Cord | Glioma of Brainstem

United States
Sabine Mueller, MD, PhD
Bristol-Myers Squibb; Pacific Pediatric Neuro-Oncology Consortium; The V Foundation...

Completed

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Glioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States, Switzerland
National Cancer Institute (NCI)

Completed

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States, Canada, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
University of Wisconsin, Madison

Not yet recruiting

Using Novel Imaging to More Safely Treat Neuroendocrine Tumors

Neuroendocrine Tumors | Somatostatin Receptor-positive Neuroendocrine Tumor

United States
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia

Endocrine Tumors | Colon Tumors | Rectum Tumors | Appendix Tumors | Peritoneum Tumors

France
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

Localized Extraskeletal Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor of Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues

United States, Canada, Saudi Arabia, Australia, New Zealand, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
National Cancer Institute (NCI)

Recruiting

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Locally Advanced Lung Neuroendocrine Neoplasm | Lung Neuroendocrine Neoplasm | Metastatic Lung Neuroendocrine Neoplasm | Recurrent Lung Neuroendocrine Neoplasm | Unresectable Lung Neuroendocrine Neoplasm | Advanced Lung Neuroendocrine Tumor | Functioning Lung Neuroendocrine Tumor | Lung Neuroendocrine... and other conditions

United States
Suzhou Transcenta Therapeutics Co., Ltd.

Recruiting

A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors

Colorectal Adenocarcinoma | Locally Advanced Solid Tumor | Metastatic Tumor

United States
Central Hospital, Nancy, France

Unknown

Osteoarticular Tumor Characterization by Advanced Imaging (TUMOSTEO)

Bone Tumor | Soft Tissue Tumor

France
GlaxoSmithKline

Completed

Japan PhI/II of GSK2118436 and GSK1120212 Combination in Subjects With BRAF V600E/K Mutation Positive Advanced Solid Tumors (Phase I Part) or Cutaneous Melanoma (Phase II Part)

Solid Tumours

Japan
University Hospital, Montpellier
Soroptimist association of Monaco

Recruiting

Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia (ALADIN)

Solid Tumor, Childhood | Pediatric Tumor | Familial Cancer | Hematological Tumor

France
Universitätsklinikum Hamburg-Eppendorf

Suspended

International HIT-MED Registry (I-HIT-MED)

Childhood Brain Tumor

Germany
Boston Scientific Corporation
ICON plc

Completed

Optimizing Pacing Therapy by Using Multi-Programmable Pulse Generators for Cardiac Resynchronization Pacing (CRT-P) (Rally CRT-P)

Post Market Surveillance Study Following Clinical Routine

Germany, Finland
Novartis Pharmaceuticals

Active, not recruiting

LUTATHERA Injection General Use Result Survey

Somatostatin Receptor-positive Neuroendocrine Tumor

Japan
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy in Patients With Malignant Rhabdoid Tumors (MRT) and Neuroblastoma

Neuroblastoma | Malignant Rhabdoid Tumors (MRT)

France, Germany, United Kingdom, United States, Australia
CNAO National Center of Oncological Hadrontherapy

Completed

Proton Boost for Locally Advanced HEAD AND NECK TUMORS

Neuroendocrine Tumors | Epithelial Tumor, Malignant

Italy
Dana-Farber Cancer Institute
Bristol-Myers Squibb; Exelixis

Completed

Cabozantinib and Nivolumab for Carcinoid Tumors

Neuroendocrine Tumors | Carcinoid Tumor | Carcinoid Tumor of GI System

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Brigham and Women's Hospital; Amgen; H. Lee Moffitt...

Completed

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

Brain Tumor | Central Nervous System Tumor

United States, Canada, Australia, Switzerland, Netherlands, New Zealand
National Cancer Institute, Naples

Recruiting

A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM) (CABOTEM)

Lung Neuroendocrine Neoplasm | GEP Neuroendocrine Tumor

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Prophylactic Cholecystectomy is Not Mandatory in Patients Candidate to the Resection for Small Intestine Neuroendocrine Neoplasms: a Propensity Score-matched and Cost-minimization Analysis

Surgery | Neuroendocrine Tumors | Gut Tumor
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Brain Tumor | Central Nervous System Tumor

United States
PharmaMar

Completed

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

Ewing's Sarcoma | Primitive Neuroectodermal Tumor (PNET) | Askin's Tumor of the Chest Wall | Extraosseous Ewing's Sarcoma (EOE)

France, United States, Italy
Centre Hospitalier Universitaire de Nīmes

Completed

Evaluation of the Reproducibility of Ablation Volumes at One Month After Microwave Treatment Compared to the Manufacturer's Abacus: on the Kidney, Liver and Lung (Ablation)

Renal Tumor | Hepatic Tumor

France
Dr. med. Mahir Karakas

Completed

Effect of Biotin on Routine Laboratory Values (SafeLab-HAM)

Biotin Ingestion | Interference With Routine Analyical Tests

Germany
Ipsen

Completed

United Kingdom (UK) Patient Preference Study of Somatuline Autogel and Treatment Administration Setting (PREF-NET)

Neuroendocrine Tumours (NET)

United Kingdom
University of Roma La Sapienza

Recruiting

Rediscovering Biomarkers for the Diagnosis and Early Treatment Response in NEN (REBORN) (REBORN)

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Neuroendocrine Neoplasm | Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1

Italy
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
St. Jude Children's Research Hospital

Recruiting

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

Solid Tumor | CNS Tumor | ALL, Adult

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors

Metastatic Gastrointestinal Carcinoid Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Regional Gastrointestinal Carcinoid Tumor

United States
Centre Leon Berard
Bayer

Active, not recruiting

A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib (LAROTRACKING)

Metastatic Cancer | Solid Tumor, Adult | Locally Advanced Solid Tumor

France
Masonic Cancer Center, University of Minnesota

Completed

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Soft Tissue Sarcoma | Medulloblastoma | Retinoblastoma | Rhabdomyosarcoma | Hepatoblastoma | Primary Malignant Brain Neoplasms | CNS Tumors | Germ Cell Tumors | Ewing's Family Tumors | Renal Tumors | Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET) | Atypical Teratoid/Rhabdoid Tumor (AT/RT)

United States
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
ARCAGY/ GINECO GROUP
Roche Pharma AG

Completed

Efficacy and Safety of Bevacizumab (Avastin®) Combined to Weekly Paclitaxel Followed by Bevacizumab (Avastin®) Alone in Patients With Relapsed Ovarian Sex-cord Stromal Tumours (ALIENOR) (ALIENOR)

Ovarian Sex-cord Stromal Tumor

France
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Longitudinal Study of Biomarkers

Central Nervous System Tumor

United States
Temple University
National Cancer Institute (NCI)

Completed

Ethical, Legal, and Social Issues Substudy in Relation to the GTEx Project (ELSI)

Standard Training | Online Training

United States
University Hospital, Bordeaux
Advanced Accelerator Applications

Recruiting

Intra-arterial Hepatic (IAH) Infusion of Radiolabelled Somatostatin Analogs in GEP-NET Patients With Dominant Liver Metastases (LUTARTERIAL)

Neuroendocrine Tumor | Liver Metastases | Neuroendocrine Gastroenteropancreatic Tumour

France
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors

Solid Tumor | Locally Advanced or Metastatic Digestive Tract Tumors

China
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); Oregon Health...

Active, not recruiting

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

Medulloblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Medulloblastoma | Germ Cell Tumor | Primitive Neuroectodermal Tumor | Medulloepithelioma | Recurrent Primitive Neuroectodermal Tumor | Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Recurrent Childhood Central Nervous System... and other conditions

United States
Dr David Ziegler
Engeneic Pty Limited

Terminated

A Study of Intravenous EEDVsMit in Children With Recurrent / Refractory Solid or CNS Tumours Expressing EGFR (ECREST)

Solid Tumours | CNS Tumours

Australia
Mabwell (Shanghai) Bioscience Co., Ltd.

Completed

Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults (MW032)

Bone Tumor

China
Assiut University

Unknown

Role of Percutaneous Vertebroplasty in Treatment of Vertebral Tumors (PVP)

Bone Tumor

Egypt
Dana-Farber Cancer Institute

Active, not recruiting

GVAX Plus Checkpoint Blockade in Neuroblastoma

Neuroblastoma | Pediatric Solid Tumor

United States
St. Jude Children's Research Hospital

Completed

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

Brain Tumors | Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors

Brain Tumors | Central Nervous System Tumors

United States, Australia, Canada
Bio-Thera Solutions
Peking University Cancer Hospital & Institute

Recruiting

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT4706 in Advanced Solid Tumors

Melanoma | Advanced Solid Tumor

China
Fudan University
Qilu Hospital of Shandong University; First Affiliated Hospital Xi'an Jiaotong... and other collaborators

Recruiting

Long-term Prognosis for Non-functional Neuroendocrine Tumors of the Pancreatic Body and Tail ≤ 3cm

Non Functioning Pancreatic Endocrine Tumor

China
Genor Biopharma Co., Ltd.

Unknown

Phase Ⅰ Clinical Study Protocol of GB223 Monoclonal Antibody Injection

Bone Tumor

China

Clinical Trials on Pontine Tumors

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Costa Rica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations