Clinical Trials on Pre-diabetes in Canada

Total 1528 results

Gilead Sciences

Completed

Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina (TERISA)

Coronary Artery Disease | Type 2 Diabetes Mellitus | Angina Pectoris

Canada, Slovenia, United States, Israel, Germany, Georgia, Russian Federation, Czech Republic, Belarus, Bulgaria, Poland, Serbia, Slovakia, Ukraine
Boehringer Ingelheim

Recruiting

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight (SYNCHRONIZE™-2)

Obesity | Diabetes Mellitus, Type 2

United States, Belgium, Korea, Republic of, Greece, Australia, Spain, Denmark, China, New Zealand, Poland, Canada, Finland, Germany, Hungary, United Kingdom, Japan, Netherlands, Sweden, Czechia
Children's & Women's Health Centre of British Columbia

Unknown

Testing the Developmental Origins Hypothesis (CHIPS-Child)

Stroke | Obesity | Diabetes

Netherlands, United States, United Kingdom, Canada, Chile, Australia, Estonia, New Zealand
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema

Diabetic Macular Edema

Spain, South Africa, Canada, Czech Republic, Germany, Israel, Australia, Portugal, United States, Philippines
Ottawa Hospital Research Institute

Enrolling by invitation

Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)

Death | Asthma | Autism Spectrum Disorder | Pre-Eclampsia | Executive Dysfunction | Emotional Problem | Behavioural Problem

Australia, United Kingdom, Canada, Jamaica
Bristol-Myers Squibb

Completed

Dose Ranging Study With LT, Monotherapy, PPAR

Diabetes Mellitus II

United States, Italy, Spain, Argentina, Brazil, Mexico, Netherlands, Puerto Rico, Canada, Sweden, Australia, Poland, France, United Kingdom, Czech Republic, South Africa
Bayer

Completed

Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Chronic Kidney Disease Alone (ARTS-HF)

Heart Failure

France, Taiwan, United States, Turkey, Spain, Greece, Portugal, Germany, Canada, Austria, Czechia, Denmark, Israel, Korea, Republic of, Poland, South Africa, Sweden, Bulgaria, Italy, Finland, Hungary, Lithuania, Netherlands, Australia, ...
Novo Nordisk A/S

Completed

Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes (STEP 10)

Obesity

United Kingdom, Canada, Denmark, Finland, Spain
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema

Diabetic Macular Edema

United Kingdom, Taiwan, Colombia, Korea, Republic of, Singapore, Brazil, New Zealand, Poland, Hungary, Italy, India, France, United States, Canada
Brigham and Women's Hospital
The Thompson Family Foundation Inc

Completed

Rural Hospital-Level Care at Home for Acutely Ill Adults

Heart Failure | Infections | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Anticoagulation | Gout Flare | Hypertensive Urgency | Atrial Fibrillation Rapid | Diabetes and Its Complications | End of Life/Desires Only Medical Management

United States, Canada
AstraZeneca

Completed

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus (THEMIS)

Diabetes Mellitus, Type 2

United States, Austria, Belgium, Canada, Denmark, France, Germany, Italy, Netherlands, Spain, United Kingdom, Czechia, Hungary, Thailand, Turkey, Vietnam, Korea, Republic of, Brazil, Peru, Philippines, Poland, China, Japan, Taiwan, Hong... and more
Gilead Sciences

Active, not recruiting

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (PURPOSE 2)

Pre-Exposure Prophylaxis of HIV Infection

United States, Thailand, Brazil, Peru, Argentina, South Africa, Mexico, Puerto Rico
Novartis Pharmaceuticals

Completed

Safety, Efficacy and Cost-efficacy of Ranibizumab (Monotherapy or Combination With Laser) in the Treatment of Diabetic Macular Edema (DME) (RESPOND)

Diabetic Macular Edema

Canada
Mannkind Corporation

Completed

Effects of URI on Diabetic Subjects Utilizing Technosphere Insulin After a Meal Challenge

Diabetes Mellitus | Upper Respiratory Infection

United States, Russian Federation, Canada
Bayer

Completed

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants (FIGARO-BM)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Spain, Belgium, United States, Russian Federation, Hong Kong, Singapore, Taiwan, Korea, Republic of, Canada, Austria, Italy, Japan, Denmark, Australia, Bulgaria, Czechia, Finland, Israel, Netherlands, Sweden, Portugal
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Pfizer
Sanofi

Completed

A Clinical Trial Assessing the Impact of the Availability of Inhaled Insulin on Glucose Control

Diabetes Mellitus

United States, Canada, Spain, Italy, United Kingdom, Germany, France
Sanofi

Completed

Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia | Inappropriate ADH Syndrome

United States, Canada, Brazil, Germany, Netherlands, Portugal, Spain, Belgium, Croatia, Hungary, Hong Kong
Sanofi

Completed

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH Safety)

Hyponatremia | Inappropriate ADH Syndrome

United States, France, Brazil, Russian Federation, Australia, Germany, Switzerland, Belgium, Hungary, Hong Kong, Canada
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Mexico, Romania, Brazil, Germany, Argentina, Czechia, Greece, Slovakia
Hoffmann-La Roche

Completed

A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab (ALTIMETER)

Diabetic Macular Edema

Germany, United States, United Kingdom, Argentina, Canada, Italy, Poland
Theravance Biopharma

Terminated

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (REDWOOD)

Parkinson's Disease (PD) | MSA | Symptomatic Neurogenic Orthostatic Hypotension | Pure Autonomic Failure (PAF)

United States, Spain, United Kingdom, Canada, France, Estonia, Australia, Israel, Denmark, Italy, Poland, New Zealand, Germany, Ukraine, Austria, Bulgaria, Portugal, Hungary, Russian Federation
VelosBio Inc.

Completed

A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Solid Tumors (MK-2140-002)

Gastric Cancer | Pancreatic Cancer | NSCLC | Platinum-resistant Ovarian Cancer | Triple-negative Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | Non-squamous Non-small-cell Lung Cancer | Estrogen-receptor-positive Breast Cancer | Progesterone-receptor-positive Breast Cancer | Estrogen-receptor-negative... and other conditions

United States, Canada
Novo Nordisk A/S

Active, not recruiting

A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease (FLOW)

Diabetes Mellitus, Type 2

Spain, United Kingdom, United States, Australia, India, Canada, Turkey, Netherlands, Italy, Poland, China, Germany, Malaysia, Israel, Hungary, Ukraine, Japan, South Africa, Russian Federation, Brazil, France, Bulgaria, Belgium, Thailand, Gree... and more
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Eli Lilly and Company
Alkermes, Inc.

Completed

Safety and Efficacy of Inhaled Insulin in Patients With Diabetes and Asthma or COPD

Diabetes Mellitus | Pulmonary Disease, Chronic Obstructive | Asthma

United States, Argentina, India, Bulgaria, Canada, Chile, Colombia, Croatia, Hong Kong, Hungary, Mexico, Philippines, Puerto Rico, Singapore, Taiwan, Thailand
Pfizer

Terminated

Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity

Obesity | Diabetes Mellitus

United States, Hungary, Canada, Japan, Poland, Puerto Rico, Bulgaria, Czechia
Amgen

Completed

Safety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemia or Mixed Dyslipidemia (BERSON)

Diabetes, Hyperlipidemia, Mixed Dyslipidemia

United States, Canada, France, Korea, Republic of, China, Argentina, Russian Federation, Colombia, Turkey, Brazil
Theravance Biopharma

Terminated

Phase 3 Open-Label Extension Study of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (OAK)

Symptomatic Neurogenic Orthostatic Hypotension

United States, Spain, Portugal, United Kingdom, France, Denmark, Ukraine, Israel, Estonia, Poland, Italy, Russian Federation, Australia, Austria, Bulgaria, Canada, Germany, New Zealand
Ian Law
The Hospital for Sick Children; Mayo Clinic; University of California, Los Angeles and other collaborators

Recruiting

ATrial Tachycardia PAcing Therapy in Congenital Heart (AT-PATCH)

Congenital Heart Disease | Atrial Tachycardia | Atrial Arrhythmia | Pacemaker Re-Entrant Tachycardia

United States, Canada
Takeda

Completed

Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.

Diabetes Mellitus

United States, Chile, Mexico, Puerto Rico
Spanish Society of Cardiology

Unknown

Second-generation Drug-eluting Stents in Diabetes (SUGAR)

Coronary Artery Disease | Diabetes Mellitus

Spain
Unity Biotechnology, Inc.

Completed

Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)

Diabetic Macular Edema (DME)

United States, Canada
McMaster University
Hoffmann-La Roche

Recruiting

Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial (INSITE-DME)

Diabetic Macular Edema

Australia, United States, Canada, United Kingdom
Takeda

Completed

Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome (EXAMINE)

Diabetes Mellitus, Type 2 | Acute Coronary Syndrome

United States, France, Italy, Poland, Ukraine, United Kingdom, Belgium, Germany, Hong Kong, Argentina, Chile, Colombia, Israel, Mexico, Portugal, Bulgaria, Malaysia, Romania, Serbia, South Africa, Japan, Canada, Finland, Taiwan, Korea,... and more
Novo Nordisk A/S

Completed

Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus

Obesity | Metabolism and Nutrition Disorder

United States, Israel, Russian Federation, United Kingdom, Canada, Belgium, Germany, Australia
Generex Biotechnology Corp.
Hoffmann-La Roche; Nextrials, Inc.; eResearch Technology, Inc.; OSMOS Clinical... and other collaborators

Unknown

Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin

Diabetes Mellitus

United States, Bulgaria, Canada, Ecuador, Poland, Puerto Rico, Romania, Russian Federation, Ukraine
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Active, not recruiting

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
Pfizer

Completed

A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

Macular Edema Associated With Diabetes Mellitus

United States, Colombia, Australia, Germany, Italy, South Africa, Greece, France, Austria, United Kingdom, Denmark, India, Portugal, Brazil, Canada, Czechia, Netherlands, Switzerland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST) (ACTFAST)

Diabetes Mellitus, Type 2 | Dyslipidemia | Peripheral Vascular Disease | Coronary Arteriosclerosis | Cerebrovascular Accident

Italy, Spain, Canada, United Kingdom, Cameroon
Pfizer

Terminated

Efficacy and Safety of Inhaled Insulin Compared With Subcutaneous Human Insulin Therapy in Adults With Type 2 Diabetes

Diabetes Mellitus

Canada, United States, Brazil, Puerto Rico
Regeneron Pharmaceuticals
Bayer

Completed

DME And VEGF Trap-Eye [Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)] INvestigation of Clinical Impact (DA VINCI)

Diabetic Macular Edema

United States, Austria, Canada
Hoffmann-La Roche

Active, not recruiting

A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular Edema

Diabetic Macular Edema

United Kingdom, Korea, Republic of, United States, Argentina, Poland, Puerto Rico, Israel, Spain, Canada
Theravance Biopharma

Completed

Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (SEQUOIA)

Symptomatic Neurogenic Orthostatic Hypotension

United States, Spain, Israel, Hungary, Portugal, Australia, Canada, Germany, Russian Federation, Estonia, France, Italy, United Kingdom, Denmark, Poland, New Zealand, Austria, Bulgaria, Ukraine
Abbott

Completed

Effectiveness and Tolerability of Tarka® in the Treatment of Hypertensive Patients With High Risk of Developing Diabetes Mellitus (TARDIA)

Hypertension

Bulgaria, Czech Republic, Romania, Russian Federation, Slovakia, Slovenia, Ukraine
Pfizer

Terminated

A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease (ILLUMINATE)

Coronary Disease | Diabetes Mellitus

United States, Spain, Australia, Canada, Sweden, Netherlands, United Kingdom
Biogen

Terminated

Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy

Diabetes Mellitus | Small Fiber Neuropathy

Bulgaria, Poland, Spain, United Kingdom, Canada, France, Czechia, Germany, Hungary, Greece, Denmark, Italy, Netherlands, Switzerland
AbbVie (prior sponsor, Abbott)

Completed

A Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

United States, Czech Republic, France, Germany, Italy, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab (Intravitreal Injections) Versus Laser Treatment in Patients With Visual Impairment Due to Diabetic Macular Edema (RED-ES)

Diabetic Macular Edema | Visual Impairment

Spain
Allergan

Terminated

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 04

Diabetes Mellitus | Gastroparesis

United States, Canada, Australia, Thailand, Korea, Republic of, Singapore, Mexico, Belgium, Bulgaria, India, Malaysia, Philippines, Poland, Spain, Ukraine, South Africa, Brazil, Colombia, Austria, Argentina, Germany, Hungary, Latvia, Russian... and more

Clinical Trials on Pre-diabetes in Canada

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