Clinical Trials on Primary Care Genetics

Total 181894 results

Baxalta now part of Shire

Completed

Immune Globulin Subcutaenous (Human), 20%

Primary Immunodeficiency Diseases (PID)

Germany, Austria, Hungary, Sweden, United Kingdom
University Hospital, Ghent

Terminated

Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening (BIOPS)

Infertility | Preimplantation Genetic Screening

Belgium
Institut Universitari Dexeus

Completed

Cumulative Live Birth Rates in Patients With Repeated Implantation Failure (RIF) Undergoing Preimplantation Genetic Screening (PGS )

Infertility | Preimplantation Genetic Screening

Spain
Mayo Clinic

Completed

Review of Kidney Biopsies of Dent Disease Patients

Dent Disease

United States
Takeda
Takeda Development Center Americas, Inc.

Not yet recruiting

A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases (PID)
Baxalta now part of Shire

Completed

A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID)

Primary Immunodeficiency Diseases (PID)

Japan
Assistance Publique - Hôpitaux de Paris

Completed

Primitive Immunodeficiency and Pregnancy (PREPI)

Primary Immune Deficiency

France
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects

Primary Immunodeficiency Diseases (PID)

Denmark, United Kingdom, Czechia, France, Greece, Hungary, Slovakia, Sweden
Baxalta now part of Shire

Completed

Phase 2/3 Study of IGSC, 20% in PIDD

Primary Immunodeficiency Diseases (PID)

United States, Canada
Baxalta now part of Shire

Completed

Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD

Primary Immunodeficiency Diseases (PID)

United States
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Real-world CANadian CUvitru Non-Interventional Study in Subjects Transitioning From Subcutaneous Immunoglobulin (CANCUN)

Primary Immunodeficiency Diseases (PID)

Canada
Institut Universitari Dexeus

Completed

The Transition From Blastomere to Trophectoderm Biopsy: Comparing Two PGS Strategies

Infertility | Preimplantation Genetic Screening
National Institute of Allergy and Infectious Diseases...

Enrolling by invitation

Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders

Primary Immunodeficiency | DOCK8 | Virus Susceptibility

United States
Queen Fabiola Children's University Hospital
Center of Human Genetics - ULB in Brussels; Interuniversity Institute of Bioinformatics...

Unknown

Method of Genetic Analysis in Genodermatoses (GENODERM)

Genodermatosis | Rare Genetic Disease With Cutaneous Expression

Belgium
Mayo Clinic

Completed

Role Of Phosphorus And FGF 23 In Patients With Dent Disease

Dent Disease

United States
University of Zurich

Recruiting

Identification of New Inborn Errors of Immunity

Primary Immune Deficiency Disorder

Switzerland
Octapharma

Completed

Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

United States
University Hospital, Caen

Completed

Pediatric Intensive Care Unit and Primary Immune Deficiency (PICUPID)

Immuno-Deficiency

France
Octapharma

Completed

Study of Octanorm Subcutaneous IG in Patients With PID

Primary Immune Deficiency Disorder

United States, Canada, Czechia, Hungary, Poland, Russian Federation, Slovakia
Ottawa Hospital Research Institute
Octapharma

Unknown

Safety, Tolerability, Patient Satisfaction and Cost of 16.5% Subcutaneous Immunoglobulin (Cutaquig®) Treatment

Primary Immunodeficiency Disease | Secondary Immunodeficiency

Canada
Rady Pediatric Genomics & Systems Medicine Institute
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Perinatal Precision Medicine (NSIGHT2)

Genetic Diseases | Genetic Syndrome | Mendelian Disorders

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Genetic Study of Obstructive Azoospermia

Genetic Disease

China
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children

Enrolling by invitation

Fluoxetine in KCNC1-related Disorder

Rare Diseases | Genetic Disease | KCNC1 Related Disorder

Canada
University of Zurich

Recruiting

Pathophysiology of Inborn Immunodeficiencies

Primary Immune Deficiency Disorder

Switzerland
Children's Hospital of Philadelphia
University of California, San Francisco

Recruiting

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Immunodeficiencies | Immune Dysregulation Syndromes

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Antibody Production in Immune Disorders

Primary Immune Deficiency

United States
Green Cross Corporation

Withdrawn

Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency Disorder
Kuwait Society for Allergy and Clinical Immunology

Completed

Primary Immunodeficiency in Kuwait

Primary Immune Deficiency Disorder

Kuwait
Karolinska University Hospital

Completed

Study of Vitamin D3 Substitution to Patients With Primary Immunodeficiency (VITAPID)

Primary Immune Deficiency Disorder

Sweden
Octapharma

Completed

Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

Russian Federation
CSL Behring

Completed

Follow-up Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency Disorder

Japan
Memorial Sloan Kettering Cancer Center

Completed

Genetic Susceptibility to Tumor Recurrence and Progression in Patients With Non-Muscle Invasive Bladder Cancer

Bladder Cancer | Urinary Cancer | Nonmuscle Invasive Bladder Cancer

United States
University Hospital, Strasbourg, France

Recruiting

Realization of Sequencing of All Known Human Genes in Case of Detection of Cerebral, Renal or Ophthalmological Fetal Malformations During Pregnancy in Order to Make an Etiological Diagnosis and to Precise the Fetal Prognosis (PRENATEX)

Pregnancy Related | Rare Genetic Disease | Fetal Malformation

France
CHU de Reims

Unknown

Tolerance and Patients' Satisfaction With IGHy

Secondary or Primary Immunodeficiency

France
New York Medical College
Johns Hopkins University; Children's Hospital of Philadelphia; Washington University... and other collaborators

Recruiting

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

Primary Immune Deficiency Disorder | Cytomegalovirus Infections

United States
University of Wisconsin, Madison
University of Wisconsin Center for Human Genomics and Precision Medicine

Recruiting

UW Undiagnosed Genetic Diseases Program

Rare Diseases | Genetic Disease | Undiagnosed Disease

United States
University of Utah
National Cancer Institute (NCI)

Completed

Risk Education and Assessment for Cancer Heredity (REACH)

Breast Cancer | Ovarian Cancer | Genetic Predisposition

United States
Professor Ernest Hung-Yu Ng

Not yet recruiting

Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing

Infertility | Aneuploidy | Genetic Disease | Chromosomal Rearrangement

China
Kedrion S.p.A.

Completed

Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency | Hypogammaglobulinemia | Agammaglobulinemia | Antibody Deficiency

United States, Canada
Retina Foundation of the Southwest
DSM Nutritional Products, Inc.; Foundation Fighting Blindness

Completed

DHA and X-Linked Retinitis Pigmentosa

Retinitis Pigmentosa | X-linked Genetic Diseases

United States
ADMA Biologics, Inc.

Completed

Study to Evaluate Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Subjects Aged 2 to 16

Humoral Immune Response

United States
National Cancer Institute (NCI)

Terminated

Parental Irradiation of Ukrainian Cleanup Workers and Evacuees and Germline Mutations in Their Offspring (Trio Study)

Genetics

Ukraine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study

Genetics

United States
National Human Genome Research Institute (NHGRI)

Completed

Physicians' Understanding of Human Genetic Variation

Genetics

United States
University Hospital Tuebingen

Recruiting

Diagnostic Research in Patients With Rare Diseases - Solving the Unsolved Rare Diseases (DiRiP-RD)

Rare Diseases | Genetic Predisposition

Germany
PTC Therapeutics

Completed

Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy

Nervous System Diseases | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Muscular Dystrophy, Duchenne | Musculoskeletal Disease

United States, Taiwan, India, Korea, Republic of, Thailand, Australia, Brazil, Bulgaria, Canada, China, Hong Kong, Malaysia, Mexico, Poland, Puerto Rico, Russian Federation, Turkey, Japan
Kedrion S.p.A.

Recruiting

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10) (KIDCARES10)

Primary Immunodeficiency Disease

Italy, United States, Portugal, Hungary, Russian Federation, Slovakia
National Institute of Allergy and Infectious Diseases...

Recruiting

The Mechanistic Biology of Primary Immunodeficiency Disorders

Primary Immunodeficiency Disorders

United States
National Institute of Allergy and Infectious Diseases...
University of Pittsburgh; PPD

Completed

Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant (BOLT-BMT)

Primary Immunodeficiency | PID

United States
Kedrion S.p.A.

Completed

Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in PID Patients (CARES10)

Primary Immunodeficiency Disease

United States

Clinical Trials on Primary Care Genetics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations