Clinical Trials on Primary Acquired Nasolacrimal Duct Obstruction in United Kingdom

Total 1366 results

Rutgers, The State University of New Jersey
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Besivance™ for Treatment of Congenital Nasolacrimal Duct Obstruction in Children

Congenital Nasolacrimal Duct Obstruction

United States
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old (NLD3)

Nasolacrimal Duct Obstruction

United States
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old (NLD2)

Nasolacrimal Duct Obstruction

United States
Thomas Gardner

Suspended

SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction (SLINDO)

Epiphora | Dacryocystorhinostomy

United States
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old (NLD1)

Nasolacrimal Duct Obstruction

United States
The Cleveland Clinic

Completed

Lacrimal Drainage Resistance Study (LDRS)

Epiphora | Ectropion | Nasolacrimal Duct Obstruction | Canalicular Stenosis | Functional Tear Pump Failure

United States
Vanderbilt University Medical Center

Recruiting

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

Thyroid Cancer | Nasolacrimal Duct Obstruction

United States
Brighton and Sussex University Hospitals NHS Trust

Completed

A Feasibility Study to Develop a Protocol for Functional Lacrimal Magnetic Resonance Imaging

Lacrimal Duct Obstruction | Lacrimal Stenosis

United Kingdom
Innovative Digestive Health Education and Research...
NinePoint Medical

Unknown

Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study (VLE-IOV)

Cholangiocarcinoma | Bile Duct Cancer | Primary Sclerosing Cholangitis | Bile Duct Diseases | Pancreatic Ductal Adenocarcinoma | Pancreas Cancer | Bile Duct Neoplasms | Biliary Stricture | Bile Duct Obstruction | Bile Duct Obstruction, Extrahepatic | Pancreatic Duct Stricture | Bile Duct Lesions | Bile Duct Neoplasms... and other conditions

United States
Vanderbilt University Medical Center

Completed

Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction

Distal Bile Duct Obstruction

United States
Boston Scientific Corporation

Completed

SpyGlass™ Discover Percutaneous

Pancreatic Diseases | Bile Duct Diseases | Bile Duct Obstruction

United States, Belgium, Italy, Canada, Germany, Hong Kong, India
Stanford University
Boston Scientific Corporation

Completed

Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP

Choledocholithiasis | Biliary Obstruction

United States
University of Edinburgh
NHS Lothian

Completed

Study to Compare Cardiovascular Side Effects of Teysuno Versus Capecitabine (TOFFEE)

Pancreatic Cancer | Gastrointestinal Cancer | Bile Duct Neoplasms | Cancer of Unknown Primary Site

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Unknown

Paternally Inherited Phenotypes in Cholestasis (PIP-C)

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

United Kingdom
California Pacific Medical Center Research Institute

Completed

Endoscopic Ultrasound Versus Endoscopic Retrograde Cholangiopancreatography (ERCP) Tissue Sampling for the Diagnosis of Suspected Pancreatico-Biliary Cancer

Jaundice | Bile Duct Obstruction | Pancreaticobiliary Cancers

United States
AdventHealth

Completed

Treatment Outcomes in Bile Duct Stones

Bile Duct Diseases | Gallstone | Bile Duct Obstruction

United States
University Hospital Birmingham NHS Foundation Trust

Recruiting

A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment of PSC-IBD (PSC-Vanc)

Inflammatory Bowel Diseases | Primary Sclerosing Cholangitis

United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis (CAMEO)

Primary Sclerosing Cholangitis (PSC)

United States, United Kingdom, Canada
University of Birmingham
National Institute for Health Research, United Kingdom; University Hospital... and other collaborators

Completed

A Trial of BTT1023 in Patients With Primary Sclerosing Cholangitis (BUTEO)

Primary Sclerosing Cholangitis

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
King's College Hospital NHS Trust; Portsmouth Hospitals NHS Trust; North Bristol... and other collaborators

Recruiting

Day-case Endourology; Enablers, Barriers, Unexpected Outcomes

Bladder Cancer | Urolithiasis | Bladder Outlet Obstruction

United Kingdom
University of Birmingham
PSC Support; Life Arc

Recruiting

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis (FARGO)

Inflammatory Bowel Diseases | Primary Sclerosing Cholangitis

United Kingdom
Wellspect HealthCare

Completed

The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects

Lower Urinary Tract Symptoms | Bladder Outlet Obstruction

United States, Netherlands, Poland, United Kingdom
Light Chain Bioscience - Novimmune SA

Terminated

Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)

Primary Biliary Cirrhosis

Italy, United Kingdom
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder and other conditions

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Exploring Novel Mechanisms of Vaccine Failure LAIV Pilot Study (LAIV)

Acquired Immune Deficiency Syndrome Virus

United Kingdom
National Cancer Institute (NCI)

Terminated

BMS-247550 in Treating Patients With Liver or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Extrahepatic Bile Duct Cancer | Localized Gallbladder Cancer | Localized Resectable Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent... and other conditions

United States
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Intercept Pharmaceuticals

Terminated

EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study (EXCITED)

Primary Biliary Cholangitis

United Kingdom
Fox Chase Cancer Center

Completed

PET-CT in Determining the Radioembolization Dose Delivered to Patients With Liver Metastasis, Primary Liver Cancer, or Biliary Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Advanced Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Adult Primary Hepatocellular Carcinoma | Metastatic Extrahepatic Bile Duct Cancer | Stage D Adult Primary Liver Cancer (BCLC)

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Unresectable Liver, Bile Duct, or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular... and other conditions

United States
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
National Cancer Institute (NCI)

Completed

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
Rodrigo Ruano

Recruiting

Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (CYSTO)

Bladder Outlet Obstruction | Lower Urinary Tract Obstructive Syndrome | Lower Urinary Tract Obstruction, Congenital | Bladder Outflow Obstruction

United States
Weill Medical College of Cornell University

Unknown

Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma

Cholangiocarcinoma | Bile Duct Cancer | Biliary Stricture | Biliary Obstruction

United States
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Perspectum

Completed

Repeatability and Reproducibility of Quantitative MRCP

Liver Diseases | Primary Sclerosing Cholangitis | Gallstones | Primary Biliary Cirrhosis

United Kingdom
Fast Forward Pharmaceuticals

Unknown

Pilot Study of FFP104 Dose Escalation in PBC Subjects

Primary Biliary Cirrhosis

Netherlands, United Kingdom
St George's, University of London
Bill and Melinda Gates Foundation; York Hospitals

Terminated

Reactogenicity and Immunogenicity of Vaginal CNgp140 (SG06RS02)

HIV Infections | Acquired Immune Deficiency Syndrome

United Kingdom
Weill Medical College of Cornell University

Unknown

Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry (RFA-Registry)

Pancreatic Cancer | Cholangiocarcinoma | Bile Duct Cancer | Biliary Stricture | Bile Duct Obstruction

United States
National Cancer Institute (NCI)

Terminated

Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Bortezomib in Treating Patients With Unresectable Locally Advanced or Metastatic Adenocarcinoma of the Bile Duct or Gallbladder

Gastrointestinal Cancer | Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder... and other conditions

United States
Papworth Hospital NHS Foundation Trust
Hinchingbrooke Healthcare NHS Trust

Completed

PAIR Study-PAP And IOP Relationship: Study 2 (PAIR2)

Primary Open-angle Glaucoma | Obstructive Sleep Apnoea

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

Hepatocellular Carcinoma | Liver and Intrahepatic Bile Duct Disorder | Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm

United States
ChemomAb Ltd.

Active, not recruiting

CM-101 in PSC Patients -The SPRING Study

Primary Sclerosing Cholangitis

United States, Germany, Israel, Spain, United Kingdom
Northwestern University
National Cancer Institute (NCI)

Completed

Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Intestine Cancer | Ovarian Cancer | Peritoneal Cavity Cancer | Gastrointestinal Stromal Tumor | Extrahepatic Bile Duct Cancer | Nausea and Vomiting | Constipation, Impaction, and Bowel Obstruction

United States
Weill Medical College of Cornell University

Unknown

T-EUS for Gastrointestinal Disorders: A Multicenter Registry (EUSERCPReg)

Pancreatic Cancer | Cholangiocarcinoma | Bile Duct Cancer | Chronic Pancreatitis | Biliary Stricture | Biliary Obstruction | Ampullary Cancer | Stent Obstruction | Proximal Duct Stricture | Distal Duct Stricture | Biliary Sphincter Stenosis | Impacted Stones | Peri-ampullary Diverticula | Altered Anatomy

United States, Brazil
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis

Primary Sclerosing Cholangitis

United States, Canada, United Kingdom, Austria
Guy's and St Thomas' NHS Foundation Trust
King's College London

Unknown

Bile Acid Effects in Fetal Arrhythmia Study (BEATS)

Intrahepatic Cholestasis of Pregnancy | Cholestasis of Pregnancy | Obstetric Cholestasis

United Kingdom
University of Alberta
GlaxoSmithKline; Axcan Pharma

Completed

Study of Combivir for Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Canada, United Kingdom
NGM Biopharmaceuticals, Inc

Completed

Phase 2 Study of NGM282 in Patients With Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis

United States, France, Netherlands, United Kingdom
North Bristol NHS Trust
University of Sheffield; University of Bristol; Newcastle University; University... and other collaborators

Unknown

Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM)

Lower Urinary Tract Symptoms | Voiding Dysfunction | Detrusor Underactivity | Benign Prostate Obstruction

United Kingdom

Clinical Trials on Primary Acquired Nasolacrimal Duct Obstruction in United Kingdom

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CROs in Tanzania

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