Clinical Trials on Primary Graft Dysfunction

Total 67050 results

Bijan Najafi, PhD
Orthotic Holdings, Inc.

Completed

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

Diabetes | Cancer | Arthritis | Parkinson's Disease | Peripheral Arterial Disease | End Stage Renal Failure on Dialysis | Accidental Falls | Fall Due to Loss of Equilibrium | High Risk of Falls Due to Mobility Limitation

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Recurrent Cervical Carcinoma | Cervical Small Cell Carcinoma | Stage III Cervical Cancer | Stage IVA Cervical Cancer | Stage IVB Cervical Cancer

United States
University Hospital, Angers
University of Angers, Angers

Unknown

Neuropsychological Assessment of Children and Adolescents With Turner Syndrome (ENEAST)

Isolated Growth Hormone Deficiency | Turner Syndrome | Pediatrics | Social Cognition | Cognitive Functions
Bloodworks
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prospective Study of HIV Infection in Hemophiliacs

HIV Infections | Acquired Immunodeficiency Syndrome | Hemophilia A | Hepatitis, Viral, Human | Blood Disease | Cytomegalovirus Infections | Blood Transfusion
Masonic Cancer Center, University of Minnesota

Completed

Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Assistance Publique - Hôpitaux de Paris

Completed

The Primordial Dwarfisms: Diagnosis, Identification of the Molecular Basis of Seckel Syndrome and Microcephalic Osteodysplastic Primordial Dwarfism Type II (NANPIM)

Seckel Syndrome | Microcephalic Osteodysplastic Primordial Dwarfism Type II

France
Boston Children's Hospital

Completed

Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

United States
Novo Nordisk A/S

Completed

Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Royal Marsden NHS Foundation Trust

Completed

Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer

Sarcoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor

Clear Cell Sarcoma of the Kidney | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Stage III Wilms Tumor | Rhabdoid Tumor of the Kidney | Stage IV Wilms Tumor | Stage V Wilms Tumor | Stage I Wilms Tumor | Stage II Wilms Tumor

United States
Mayo Clinic
Johns Hopkins University; University of Southern California; National Center...

Completed

Assessing the Patient Experience in Cancer Care

Melanoma | Sarcoma | Breast Neoplasm | Brain Neoplasm | Endocrine Gland Neoplasm | Head and Neck Neoplasm | Lung Neoplasm | Gastrointestinal Neoplasm | Genitourinary Neoplasm | Gynecological Neoplasm

United States
Michael Morse, MD
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer

Testicular Germ Cell Tumor | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Liver Cancer | Gallbladder Cancer

United States
Novo Nordisk A/S

Completed

Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Forbes Porter, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Simvastatin Therapy in Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

United States
University Hospital Muenster

Completed

Pharmacokinetic Study of Doxorubicin in Children With Cancer (Doxo)

Soft Tissue Sarcoma | Acute Lymphoblastic Leukemia | Neuroblastoma | Wilms Tumor

Germany, France, United Kingdom, Italy
European Organisation for Research and Treatment...

Completed

Incidence of Blood Clots in Patients Undergoing Chemotherapy for Solid Tumors

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Thromboembolism

Netherlands
National Cancer Institute (NCI)

Completed

GTI-2040 and Docetaxel in Treating Patients With Recurrent, Metastatic, or Unresectable Locally Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Other Solid Tumors

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage III Prostate Cancer | Stage IV Prostate Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

Canada
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Completed

Isotretinoin Plus Interferon in Treating Patients With Recurrent Cancer

Cervical Cancer | Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Penile Cancer | Non-melanomatous Skin Cancer

United States
Samsung Medical Center

Completed

Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation

Mycoses | Brain Tumor | Neuroblastoma | Retinoblastoma | Wilms Tumor

Korea, Republic of
National Center for Research Resources (NCRR)
James Whitcomb Riley Hospital for Children

Completed

Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes

Thrombocytopenia | Dyskeratosis Congenita | Fanconi's Anemia | Shwachman Syndrome
National Cancer Institute (NCI)

Completed

RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States, Canada
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent... and other conditions

United States, Puerto Rico
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
National Cancer Institute (NCI)

Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Urethral Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Bladder Adenocarcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Bladder... and other conditions

United States, Puerto Rico
M.D. Anderson Cancer Center

Active, not recruiting

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Malignant Solid Neoplasm | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Unresectable Melanoma | Clinical Stage III Cutaneous... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Castleman Disease | Lymphangioleiomyomatosis | Digestive System Carcinoma | Malignant Neoplasm | Recurrent Breast Carcinoma | Recurrent Thyroid Gland Carcinoma | Metastatic Urothelial Carcinoma | Malignant Female Reproductive System Neoplasm | Neurofibromatosis Type 2 | Recurrent Adult Soft Tissue Sarcoma and other conditions

United States
Caroline Michaela Kistorp
Sanofi

Not yet recruiting

Fibrosis, Inflammation, Oxygenation of Renal Tissue In FabrY Disease (FORTIFY)

Chronic Kidney Diseases | Fabry Disease

Denmark
Athens LifeTech Park
Galatea.Bio

Recruiting

A Clinical Study to Map the HLA Genomic Region in the Greek Population (GENESIS)

Gastrointestinal Diseases | Cardiovascular Diseases | Healthy | Neurologic Disorder | Respiratory Disease | Psychiatric Disorder | Chronic Renal Failure | Metabolic Disease | Haematologic Disease | Rheumatologic Disease

Greece
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Ovarian Endometrioid Adenocarcinoma | Endometrial Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | Endometrial Low Grade Endometrioid... and other conditions

United States
Gene Surgery LLC

Recruiting

Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid

Melanoma | Sarcoma | Uterine Cervical Neoplasms | Breast Neoplasms | Squamous Cell Carcinoma of Head and Neck | Vulvar Neoplasms | Anus Neoplasms | Penile Neoplasms

Russian Federation
University of Sydney
Austin Health; Peter MacCallum Cancer Centre, Australia; Western Sydney Local... and other collaborators

Not yet recruiting

LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology (LEARN)

Kidney Cancer | Breast Cancer | Head and Neck Cancer | Arrhythmias, Cardiac | Pancreatic Cancer | Brain Cancer | Liver Cancer | Prostatic Cancer | Spinal Neoplasm

Australia
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Endometrial Clear Cell Adenocarcinoma | Endometrial Dedifferentiated Carcinoma | Endometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Recurrent Endometrial Carcinoma | Endometrial Adenocarcinoma | Endometrioid Adenocarcinoma | Endometrial...

United States
Fundacion para la Investigacion Biomedica del Hospital...
University of Alcala; Hospital Universitario Ramon y Cajal; Instituto de Salud... and other collaborators

Recruiting

Prevalence of Hyperandrogenism in Type 1 Diabetes

Polycystic Ovary Syndrome | Hyperandrogenism | Type 1 Diabetes | Hirsutism | Oligomenorrhea | Ovulation Disorder

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Cord Blood-Derived Mesenchymal Stem Cells for the Treatment of COVID-19 Related Acute Respiratory Distress Syndrome

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | COVID-19 Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed | COVID-19-Associated Acute Respiratory Distress Syndrome

United States
Amgen

Recruiting

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer

Chemotherapy-induced Thrombocytopenia

United States, Spain, Turkey, Argentina, Greece, Austria, Brazil, Bulgaria, Chile, Colombia, Mexico, Peru, Poland, Portugal, Romania, Russian Federation, Ukraine, Hungary
Joshua Mann, MPH
National Organization for Rare Disorders

Recruiting

MyVHL: Patient Natural History Study (MyVHL)

Von Hippel-Lindau Disease | Hereditary Leiomyomatosis and Renal Cell Cancer | Birt-Hogg-Dube Syndrome | SDHB Gene Mutation

United States
Precision Biologics, Inc

Recruiting

Study of NEO-201 in Solid Tumors Expansion Cohorts

Cervical Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Uterine Cancer

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Recruiting

Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

Diabetes Mellitus | Deafness | Ataxia | Diabetes Insipidus | Wolfram Syndrome | Optic Nerve Atrophy

United States
National Cancer Institute (NCI)

Recruiting

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Chronic Lymphocytic Leukemia (CLL) | Hairy Cell Leukemia (HCL) | Cutaneous T Cell Lymphoma (CTCL) | Non-Hodgkins Lymphoma (NHL) | Adult T Cell Lymphoma (ATL)

United States
National Cancer Institute (NCI)

Suspended

Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery

Malignant Solid Neoplasm | Multiple Myeloma | Breast Carcinoma | Colon Carcinoma | Kidney Carcinoma | Prostate Carcinoma | Liver Carcinoma | Invasive Carcinoma

United States
TransThera Sciences (Nanjing), Inc.

Completed

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Sarcoma | Gastric Cancer | Prostate Cancer | Cholangiocarcinoma | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Small-cell Lung Cancer | Thyroid Cancer | Gallbladder Cancer | HER2-negative Breast Cancer

United States
Istituti Clinici Scientifici Maugeri SpA
University of Pavia; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

Pilot Study of the eHealth Application "Cancer Patients Better Life Experience" (CAPABLE) - Italy (CAPABLE-IT)

Stomach Cancer | Breast Cancer | Head and Neck Cancer | Lung Cancer | Thyroid Cancer | Renal Cell Carcinoma Metastatic | Ovary Cancer

Italy
VA Office of Research and Development

Enrolling by invitation

Goals of Care Conversations Study (LSTDI)

Heart Failure | Cancer | Chronic Obstructive Pulmonary Disease | Dementia | Interstitial Lung Disease | End-stage Renal Disease | Seriously Ill Patients | End-stage Liver Disease

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; AIDS and Cancer Specimen Resource

Active, not recruiting

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

HIV Infection | Anal Squamous Cell Carcinoma | Stage 0 Anal Canal Cancer | Stage I Anal Canal Cancer

United States
Amgen

Active, not recruiting

A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications

Non-squamous Non-small Cell Lung Cancer | Epithelial Ovarian Cancer | Claudin 6-positive Advanced/Metastatic Malignant Solid Tumors

United States, Australia, Switzerland
Cancer Research UK

Active, not recruiting

A CR-UK Phase I Trial of LY3143921

a. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...

United Kingdom
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer

Metastatic Prostate Carcinoma | Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage IV Renal... and other conditions

United States, Puerto Rico
Genmab
AbbVie

Terminated

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Esophageal Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer (NSCLC) | Uterine Cancer | Triple Negative Breast Cancer (TNBC) | Squamous Cell Carcinoma of Head and Neck (SCCHN) | Locally Advanced or Metastatic Solid Tumor(s)

Spain, Israel, United States, Denmark
Jonsson Comprehensive Cancer Center
BeiGene; Driven To Cure

Withdrawn

Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer

Metastatic Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Unresectable Renal Cell Carcinoma | Hereditary Leiomyomatosis and Renal Cell Carcinoma | Clear Cell Papillary Renal Neoplasm | Hereditary Papillary Renal Cell Carcinoma and other conditions

United States

Clinical Trials on Primary Graft Dysfunction

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