Clinical Trials on Primary Mediastinal LBCL

Total 59997 results

Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
The Third Xiangya Hospital of Central South University

Recruiting

Clinical Research on a Novel Deep-learning Based System in Mediastinal Endoscopic Ultrasound Scanning

Mediastinum Disease

China
Ruijin Hospital

Recruiting

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

Primary Mediastinal Large B Cell Lymphoma | EBV-Positive DLBCL, Nos

China
Yonsei University

Completed

Echocardiographic Evaluation of the Change on Pulmonary Blood Flow and Cardiac Function Induced by Capnothorax During One Lung Ventilation

Mediastinal Tumors
M.D. Anderson Cancer Center

Recruiting

PACIFIC: Primary Mediastinal Large B-cell Lymphoma Treated With Antibody Therapy, Checkpoint Inhibitor in Frontline With ImmunoChemotherapy (PACIFIC)

Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Ann Arbor Stage II Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Ann Arbor Stage III Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Ann Arbor Stage IV Primary Mediastinal (Thymic) Large B-Cell Lymphoma

United States
Yonsei University

Not yet recruiting

Effects of Iloprost on Oxygenation During One-lung Ventilation in Supine-positioned Patients

Mediastinal Mass

Korea, Republic of
Sun Yat-sen University

Recruiting

MR-linac Guided Adaptive Radiotherapy for Inoperable Mediastinal Tumor

Mediastinal Tumor

China
Baylor College of Medicine

Completed

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation (EBUS-GA-MS)

Mediastinal Lymphadenopathies | Mediastinal Masses | Hilar Lymphadenopathies

United States
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Classical Hodgkin Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma (DLBCL)

Italy
Instituto Nacional de Cancerologia de Mexico

Active, not recruiting

Oscillating Positive Expiratory Pressure Therapy for Patients With Thoracic Neoplasms Undergoing Chest Surgery (AEROBIKA)

Lung Cancer | Mediastinal Tumor | Pleural Tumor

Mexico
Assiut University

Unknown

Assessment of Mediastinal Masses With Diffusion Weighted MR Imaging

Mediastinal Tumor

Egypt
Xueying Yang

Completed

Totally no Tube (TNT) Uniportal Video-assisted Thoracoscopic Surgery (VATS) VS Traditional Uniportal VATS for Mediastinal Tumor

Mediastinal Tumor

China
Tongji Hospital

Unknown

Application Study of 12G Pigtail Catheter Used for Post-operative Drainage After Thoracoscopic Surgery for Mediastinal Nodes

Mediastinal Nodes
Medical University of Warsaw
Warsaw University of Technology

Unknown

Virtual Bronchoscopy (VB) vs. Endobronchial Ultrasound (EBUS) Guided Mediastinal Sampling (VB/EBUS-TBNA)

Lung Cancer, | Mediastinal Tumors, | Lymphomas, | Sarcoidosis,

Poland
University Hospital, Gentofte, Copenhagen
University Hospital Schleswig-Holstein; University of Medicine and Pharmacy... and other collaborators

Completed

Controlled Trial Comparing the Performance of 22 Gauge Versus 25 Gauge EUS-FNA Needles (FNA-22G-25G)

Pancreatic Masses | Liver Masses | Mediastinal Tumours and Lymph Nodes | Celiac, Perigastric and Peri-pancreatic Lymph Nodes | Adrenal Masses

Denmark, Germany, Romania
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Bio-CAR-T BS Study

Acute Lymphoblastic Leukemia (ALL) | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma (DLBCL)

Italy
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Predicting Malignancy Using Endoluminal Ultrasound Characteristics in Mediastinal Lymph Nodes (CT0024)

Neoplasm of Mediastinal Lymph Nodes

Canada
Jennifer Crombie, MD
Merck Sharp & Dohme LLC

Recruiting

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Primary Mediastinal Large B Cell Lymphoma | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma Refractory | Primary Mediastinal Large B-Cell Lymphoma Recurrent | Epstein-Barr Virus Positive Diffuse Large...

United States
Acepodia Biotech, Inc.

Recruiting

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Marginal Zone Lymphoma | Non Hodgkin Lymphoma | DLBCL | Primary Mediastinal Large B Cell Lymphoma

United States, Taiwan
IRB of NTUH Hsin-Chu Branch

Completed

Needlescopic-assisted Uniportal vs Uniportal VATS (UNeed)

Lung Cancer | Lung Cancer Metastatic | Mediastinal Tumor | Nodule Solitary Pulmonary | Bullous Disease Lung

Taiwan
Tanta University

Completed

Value of Rapid on Site Evaluation During EBUS-guided TBNA in the Diagnosis of Mediastinal Lesions

Mediastinum

Egypt
China-Japan Friendship Hospital

Recruiting

Study on Transbronchial Ultrasound-guided Cryobiopsy in the Diagnosis of Mediastinal Lymphadenopathy

Mediastinal Lymphadenopathy

China
National Research Center for Hematology, Russia

Recruiting

Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL

Primary Mediastinal Lymphoma

Russian Federation
National Taiwan University Hospital

Unknown

Dx Mediastinal Malignant LAP:Compare PET and EBUS-TBNA

Mediastinal Lymphadenopathy

Taiwan
Azienda Sanitaria-Universitaria Integrata di Udine

Completed

Coronavirus Associated Pneumomediastinum and Pneumothorax (COVI-MIX)

Pneumothorax | COVID-19 Pneumonia | Pneumomediastinum

Italy
Sheba Medical Center

Unknown

Feasibility of Confocal Laser Microscopy (CLM)in the Computed Tomography-guided Needle Biopsy of Pulmonary and Mediastinal Lesions

Pulmonary and Mediastinal Lesions

Israel
Tanta University

Completed

The Role of Endobronchial Ultrasound Elastography in the Diagnosis of Mediastinal Lesions

Mediastinum

Egypt
All India Institute of Medical Sciences, New Delhi

Completed

EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions (TEAM)

Mediastinum

India
European Organisation for Research and Treatment...

Completed

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer

Testicular Germ Cell Tumor | Metastatic Cancer | Mediastinal Cancer

United Kingdom, Norway, Switzerland, Spain, Belgium, Netherlands, Germany, Denmark, Slovakia, Italy, Austria, Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Transarterial Chemoembolization for the Treatment of Lung Cancer

Lung Non-Small Cell Carcinoma | Mediastinal Neoplasm | Pleural Neoplasm

United States
Third Military Medical University
Heidelberg University

Completed

Transbronchial Mediastinal Cryobiopsy Combined With EBUS-TBNA in the Diagnosis of Mediastinal Lesions

Mediastinal Lymphadenopathy

China, Germany
Royal Brompton & Harefield NHS Foundation Trust

Unknown

EBUS-TBNA vs Acquire TBNB

Mediastinal Lymphadenopathy

United Kingdom
Hannover Medical School

Unknown

Accuracy and Safety of Endobronchial Ultrasound (EBUS) in Suspected Non-malignant Mediastinal Lymphadenopathy (EBUS-nonM)

Mediastinal Lymphadenopathy
China-Japan Friendship Hospital

Not yet recruiting

The Comparisonof Mediastinal/Hilar Lymph Node Biopsies by EBUS-TBNA, EBUS-TBCB, and EBUS-TBFB

Lymphadenopathy Hilar | Lymphadenopathy Mediastinal
Memorial Sloan Kettering Cancer Center
Takeda

Recruiting

Study of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Lymphoma

B-Cell Lymphoma | Large B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | Mediastinal Large B-cell Lymphoma | High-grade B Cell Lymphoma

United States
Sanjay Gandhi Postgraduate Institute of Medical...

Completed

Diagnostic Yield & Specimen Adequacy of Flex 19 G vs 22 G EBUS Needle - A Randomized Controlled Trial (EBUS-TBNA)

Mediastinal Lymphadenopathy | Hilar Lymphadenopathy

India
Northwell Health

Completed

Endobronchial Ultrasound Transbronchial Needle Aspiration Using Needle Suction Versus No Suction

Mediastinal Lymphadenopathy | Lung Malignancies

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Recurrent Classic Hodgkin Lymphoma | Refractory... and other conditions

United States
Lei Jiang

Recruiting

Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS

Thoracic Surgery | Thoracic Neoplasm | Mediastinal Neoplasms

China
Peking Union Medical College Hospital

Recruiting

Establishing Prospective Mediastinal Tumor Database of PUMCH (MTDPUMCH)

Lymphoma | Thymic Epithelial Tumor | Teratoma | Schwannoma | Germ Cell Tumor | Thymic Cyst | Retrosternal Goitre

China
Tel-Aviv Sourasky Medical Center

Unknown

Video-guided Percutaneous Tracheostomy (PCT) Versus Conventional PCT: Comparing Safety and Efficacy

Pneumothorax | Hypoxia | Bleeding | Atelectasis | Pneumomediastinum

Israel
Memorial Sloan Kettering Cancer Center

Completed

Chemoembolization for Lung Tumors

Lung Metastases | Endobronchial Metastases | Pleural Metastases | Mediastinal Metastases

United States
David Bond, MD
Bristol-Myers Squibb

Active, not recruiting

Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

Diffuse Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | Transformed Non-Hodgkin Lymphoma | Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage... and other conditions

United States
Dan Liu

Recruiting

Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

Mediastinal Diseases

China
Fondazione Italiana Linfomi - ETS
Janssen-Cilag S.p.A.

Recruiting

Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance

DLBCL

Italy
Mayo Clinic
National Cancer Institute (NCI)

Completed

Nivolumab and Pomalidomide in Treating Patients With Relapsed or Refractory Central Nervous System Diffuse Large B Cell Lymphoma or Primary Vitreoretinal Diffuse Large B Cell Lymphoma

Recurrent Nervous System Lymphoma | Recurrent Primary Vitreoretinal DLBCL | Refractory Nervous System Lymphoma | Refractory Primary Vitreoretinal DLBCL

United States
Curocell Inc.

Recruiting

Study of Efficacy and Safety of CRC01 in Adult Large B-cell Lymphoma Patients

High-grade B-cell Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Primary Mediastinal Large B-Cell Lymphoma (PMBCL) | Transformed Follicular Lymphoma (TFL) | Refractory Large B-cell Lymphoma | Relapsed Large B-cell Lymphoma

Korea, Republic of
Pierre Wauthy

Completed

Post-Surgical Mediastinitis Within the CHU Brugmann Hospital

Mediastinitis

Belgium
Tel-Aviv Sourasky Medical Center

Unknown

Video-guided Percutaneous Tracheostomy (PCT): A Feasibility Study

Pneumothorax | Hypoxia | Bleeding | Atelectasis | Pneumomediastinum

Israel
Tang-Du Hospital

Recruiting

The Safety and Efficacy of "3-Hole" Subxiphorid Approach in the Treatment of Anterior Mediastinal Tumor (3-Hole)

Myasthenia Gravis | Thymectomy

China

Clinical Trials on Primary Mediastinal LBCL

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