Clinical Trials on Protein Overload in Canada

Total 461 results

Clinical Evaluation Research Unit at Kingston General...

Completed

Phosphate Bioavailability Hormonal Response to a Breakfast Meal in Healthy Humans

Phosphate Overload

Canada
Nova Scotia Health Authority

Not yet recruiting

Effect of High-Flow Nasal Cannula on IVC Measurements Using Point of Care Ultrasound

Fluid Overload

Canada
Sunnybrook Health Sciences Centre
University Health Network, Toronto; Canadian Blood Services

Completed

Transfusion-Associated Circulatory Overload Best Eliminated With Lasix

Transfusion-associated Circulatory Overload

Canada
University of Alberta

Completed

Target Weight Correction and Vascular Stiffness in Hemodialysis Patients

Fluid Overload | Vascular Stiffness

Canada
Andrea Kew

Completed

Safety and Efficacy of Iron Reduction by Phlebotomy

Iron Overload

Canada
ApoPharma

Completed

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload (TWICE)

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Greece, Italy
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Deferasirox in Combination With Deferoxamine Followed by Deferasirox Monotherapy in Severe Cardiac Iron Overload (HYPERION)

Cardiac Iron Overload

Taiwan, Egypt, Thailand, Turkey, United Kingdom, Italy, Canada, Greece
Shire

Terminated

Study for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)

Iron Overload Due to Repeated Red Blood Cell Transfusions

Canada, United States, Thailand, Italy, United Kingdom
Shire

Terminated

Pharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Lebanon, Italy, Egypt
University Health Network, Toronto

Completed

MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias (MAFIO)

Thalassemia Major | Chronic Blood Transfusion Related Iron Overload

Canada
McMaster University

Completed

Influence of Reduced Daily Step Count and Anabolic Interventions on Muscle Protein Metabolism in Older Persons

Older Adults | Muscle Protein Synthetic Response to Protein | Reduced Physical Activity

Canada
McGill University Health Centre/Research Institute...

Completed

Effect of Intravenous Nutrition and Epidural Analgesia on Protein Loss After Surgery

Postoperative Protein Catabolism

Canada
PepsiCo Global R&D

Completed

Effect of Protein-nutrition Beverages on Muscle Protein Synthesis in Women

Muscle Protein Synthesis

Canada
McGill University Health Centre/Research Institute...

Completed

The Effect of Intravenous Nutrition in Patients Undergoing Abdominal Surgery

Postoperative Protein Catabolism

Canada
Hamilton Health Sciences Corporation
McMaster University

Withdrawn

Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery (RAPPER-MAN)

Coronary Artery Disease | Fluid Overload | Hemodilution

Canada
McMaster University

Completed

Effect of Protein Quality During Overreaching in Trained Cyclists

Muscle Protein Synthesis

Canada
University of Western Ontario, Canada

Unknown

Measuring Protein Requirement Using Amino Acid Oxidation in Strength and Endurance Athletes

Protein Requirement of Athletes

Canada
McMaster University

Completed

The Effects Potato Protein on Rates of Myofibrillar Muscle Protein Synthesis in Young Women (APRE)

Muscle Protein Synthesis

Canada
McMaster University

Active, not recruiting

Effect of Exercise on the Human Skeletal Muscle Phosphoproteome

Skeletal Muscle Protein Synthesis

Canada
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR)

Completed

Determination of Protein Requirements in Elderly Female Subjects >75 Yrs Old

Healthy Females | Protein Requirement

Canada
University of Toronto

Recruiting

A 'Non-Invasive' Breath Test to Determine Anabolic Sensitivity in Females (FBT)

Resistance Exercise | Dietary Protein | Female Protein Metabolism | Anabolic Sensitivity | Young Adult Females

Canada
McMaster University
Canadian Institutes of Health Research (CIHR); University of California, Davis and other collaborators

Completed

Role of Leucine in the Regulation of Human Myofibrillar Protein Synthesis at Rest and Following Resistance Exercise

Regulation of Muscle Protein Synthesis

Canada
Shire

Terminated

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Beta-Thalassemia | Transfusional Iron Overload

United States, Lebanon, Canada, Italy, Turkey
Unity Health Toronto
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Role of Active Deresuscitation After Resuscitation: (RADAR-Canada)

Sepsis | Critical Illness | Trauma | ARDS | Fluid Overload

Canada
McMaster University

Active, not recruiting

Menstrual Cycle Phase Muscle Protein Synthesis

Muscle Protein Synthesis | Menstrual Cycle | Resistance Exercise

Canada
McMaster University

Completed

Effect of Supplementing a Mixed Macronutrient Beverage With Graded Doses of Leucine on Myofibrillar Protein Synthesis

Muscle Protein Synthesis

Canada
McMaster University

Completed

The Effect of Whole Milk to Improve Muscle Health in Older Women

Physical Activity | Aging | Muscle Protein Synthesis | Dairy Products

Canada
Centre hospitalier de l'Université de Montréal...
Sunnybrook Health Sciences Centre; University of Alberta; Unity Health Toronto; University of Kentucky and other collaborators

Completed

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury (ECHO-AKI)

Acute Kidney Injury | Ultrasonography | Fluid Overload

Canada, United States
University of Toronto

Completed

Influence of Habitual Protein Intake on AA Tracer Oxidation (HPI)

Protein/Amino Acid Metabolism | Indicator Amino Acid Oxidation Method

Canada
University of Toronto
Dairy Management Inc.

Recruiting

Determining the Effect of Protein Quality on Post-exercise Anabolism in Active Youth (PQS)

Dietary Proteins

Canada
McGill University Health Centre/Research Institute...

Active, not recruiting

Egg Allergy Oral Desensitization

Egg Protein Allergy

Canada
University of Toronto
Natural Sciences and Engineering Research Council, Canada

Completed

Influence of Sex and Training on de Novo Muscle Protein Synthesis (TUT)

Resistance Exercise | Amino Acids | Dietary Protein | Sex

Canada
Evergrain, LLC
INQUIS Clinical Research Ltd.

Completed

Effect of EverVita Pro, a Protein Rich Ingredient, on Satiety Measures, Subsequent Energy Intake, and Gastrointestinal Symptoms: A Randomized, Controlled, Cross-over Study in Healthy Subjects

Satiety of High Fiber High Protein Bread

Canada
Novartis Pharmaceuticals

Completed

Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload (CORDELIA)

Transfusional Hemosiderosis | Transfusional Iron Overload

Taiwan, Turkey, Egypt, United Kingdom, Thailand, Canada, China, Italy, Cyprus, Lebanon, United Arab Emirates
University of Toronto
Dairy Management Inc.

Recruiting

The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth (PBS)

Dietary Proteins | Indicator Amino Acid Oxidation

Canada
Novartis Pharmaceuticals

Completed

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Transfusion-dependent Anemia

Egypt, Hungary, Turkey, United States, Bulgaria, Italy, Belgium, Russian Federation, Philippines, France, Malaysia, India, Oman, Panama, Lebanon, Thailand, Tunisia
University of Toronto

Recruiting

Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States (BTLP)

Physical Inactivity | Resistance Exercise | Amino Acids | Dietary Protein

Canada
Kevin H.M. Kuo, MD, MSc, FRCPC

Unknown

Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients (CANALI)

Iron Overload | Beta-Thalassemia

Canada
Hamilton Health Sciences Corporation

Completed

Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial (FADE)

Edema | Hypoproteinemia

Canada
University Health Network, Toronto

Recruiting

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (TICATS)

Thalassemia Major

Canada
McGill University

Completed

Ketones and Muscle Protein Synthesis

Ketosis | Regulation of Muscle Protein Synthesis

Canada
Novartis Pharmaceuticals

Completed

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload in β-thalassemia

United States, Greece, Argentina, Germany, Belgium, Italy, United Kingdom, France, Tunisia, Canada, Turkey, Brazil
Abfero Pharmaceuticals, Inc

Withdrawn

SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias

Iron Overload | Beta-Thalassemia

Thailand, Lebanon, Turkey, Canada
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Withdrawn

Hypoalbuminemia in Burn Patients (Halburns)

Second or Third Degree Burns

Canada
Protagonist Therapeutics, Inc.

Completed

PTG-300 in Subjects With Hereditary Hemochromatosis

Hereditary Hemochromatosis

United States, Canada
University Health Network, Toronto
CSL Behring

Completed

Subcutaneous Ig in Allogeneic Stem Cell Transplant Recipients (ScIGalloHCT)

Hypogammaglobulinemia

Canada
McGill University Health Centre/Research Institute...
McGill University

Completed

Whey Protein-based Enteral Nutrition Support to Improve Protein Economy in Surgical Patients

Colorectal Neoplasms | Protein Metabolism

Canada
University of Toronto
University of Saskatchewan; Saskatchewan Food Industry Development Center

Recruiting

Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults (PLO)

Obesity | Malnutrition; Diabetes | Malnutrition; Protein

Canada
University of Toronto

Recruiting

Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels (ARBT)

Sarcopenia | Aging | Sedentary Behavior | Amino Acids | Dietary Protein

Canada
LMU Klinikum
Seventh Framework Programme; NBIA Alliance

Recruiting

TIRCON International NBIA Registry (TIRCON)

Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions

Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain

Clinical Trials on Protein Overload in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Paraguay

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