Clinical Trials on Pulmonary Failure in United Kingdom

Total 7137 results

Brunel University
Nottingham City Primary Care Trust

Withdrawn

Evaluation of Remote Patient Monitoring.

Chronic Obstructive Pulmonary Disease | Congestive Heart Failure

United Kingdom
NHS Greater Glasgow and Clyde

Terminated

Bisoprolol in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease

Heart Failure | Chronic Obstructive Pulmonary Disease

United Kingdom
GlaxoSmithKline

Completed

A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients

Oedema, Pulmonary

United Kingdom
GlaxoSmithKline

Completed

Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure

Heart Failure, Congestive

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Withdrawn

Investigating a Well-being Review in Pulmonary Hypertension

Pulmnary Hypertension

United Kingdom
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN)

Persistent Pulmonary Hypertension of the Newborn | Hypoxic Respiratory Failure | PPHN

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure (CRF-QoL)

Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Respiratory Failure | Ventilatory Failure

United Kingdom
GlaxoSmithKline

Completed

A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure

Heart Failure, Congestive

United Kingdom
Bial - Portela C S.A.
Covance

Completed

Effect of BIA 5 1058 on Cardiac Repolarization

Heart Failure | Cardiovascular Disease | Pulmonary Arterial Hypertension

United Kingdom
Michelle Ramsay
Royal Brompton & Harefield NHS Foundation Trust

Completed

Patient -Ventilator Interaction in Chronic Respiratory Failure

Chronic Obstructive Pulmonary Disease | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chronic Hypercapnic Respiratory Failure

United Kingdom
Victor Tapson, MD
Bristol-Myers Squibb

Terminated

Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism (SAFE-LYSE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure | Pulmonary Embolism With Acute Cor Pulmonale | Pulmonary Embolism With Pulmonary Infarction | Pulmonary Embolism Subacute Massive

United States
Kronikgune
Odense University Hospital; Assuta Ashdod Hospital; Maccabi Healthcare Services... and other collaborators

Recruiting

Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients (ADLIFE)

Heart Failure NYHA Class III | Heart Failure NYHA Class IV | Chronic Obstructive Pulmonary Disease Severe

Denmark, Germany, Israel, Spain, Sweden, United Kingdom
Helse Stavanger HF
Pfizer

Unknown

Sildenafil Versus Placebo in Chronic Heart Failure (SilHF)

Heart Failure | Pulmonary Hypertension

United Kingdom, Israel, Norway, Italy
Asante Health System
Health Resources and Services Administration (HRSA)

Completed

A Trial to Reduce Readmissions Using Motivational Interviewing and Interactive Voice Response

Chronic Obstructive Pulmonary Disease (COPD) | Congestive Heart Failure (CHF)

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Suspended

Development of Novel Physiological CMR Methods in Health and Disease

Myocardial Infarction | Coronary Artery Disease | Heart Failure | Pulmonary Hypertension

United Kingdom
King's College Hospital NHS Trust
University of Brighton

Completed

The Effects of a Home Exercise Video Programme for Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Papworth Hospital NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Serum Bio-markers in Pulmonary Hypertension

Pulmonary Hypertension, Primary, 4

United Kingdom
University College, London
University of Cambridge; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
Restech Srl
Uppsala University; University Hospital of North Norway; University of Lincoln; University of Liverpool and other collaborators

Completed

Clinical Trials for Elderly Patients With Multiple Disease (CHROMED)

Chronic Obstructive Pulmonary Disease (COPD) | Congestive Heart Failure (CHF) | Sleep Disordered Breathing (SDB)

Spain, United Kingdom, Sweden, Estonia, Slovenia
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Terminated

The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients

Chronic Obstructive Pulmonary Diseases

United Kingdom
AstraZeneca

Terminated

Effect of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease (TREAT)

Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)

ASTHMA | CHRONIC OBSTRUCTIVE PULMONARY DISEASE | HEALTHY SUBJECTS

United Kingdom
University of East Anglia

Unknown

Maintenance Schedules Following Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease | Pulmonary Rehabilitation

United Kingdom
Imperial College London

Completed

Auto-titrating Oxygen in Chronic Respiratory Failure (ASI1)

Chronic Obstructive Pulmonary Disease | Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Free Hospital NHS Foundation Trust
Fisher and Paykel Healthcare; Royal Free Charity

Active, not recruiting

Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom

Chronic Obstructive Pulmonary Disease | Chronic Hypercapnic Respiratory Failure | Health-related Quality of Life | Obesity Hypoventilation Syndrome (OHS) | Nasal High Flow

United Kingdom
National Services for Health Improvement Ltd
GlaxoSmithKline

Completed

Characterisation of People With COPD (CoCO)

Chronic Obstructive Pulmonary Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

NRD to Predict COPD Exacerbations at Home

Chronic Obstructive Pulmonary Disease

United Kingdom
Philips Respironics

Completed

Evaluating Forced Oscillation Technique (FOT) in Abolishing Flow Limitation

Chronic Obstructive Pulmonary Disease

United Kingdom
GlaxoSmithKline
University of Cambridge

Completed

Effects Of Oral Prednisolone On Bone Metabolism In Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure

Chronic Obstructive Pulmonary Disease | Respiratory Failure | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chest Wall Disorder

United Kingdom
AstraZeneca
Parexel; Covance; The Doctors Laboratory; Industrias Farmacéuticas Almirall S.A.

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Male Japanese Subjects

Chronic Obstructive Pulmonary Disease - COPD

United Kingdom
ResMed

Completed

Ventilator Monitoring in Early Exacerbation Detection

Chronic Obstructive Pulmonary Disease | Respiratory Failure | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chest Wall Disorder

United Kingdom
Pulmatrix Inc.

Completed

A Phase 1b Study of PUR1800 in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Alung Technologies

Completed

ECCO2R as an Adjunct to NIV in AECOPD

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Dundee

Completed

Chronic Beta-blockade and Cardiopulmonary Exercise in COPD (CPET1)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Nottingham

Completed

The Effect of Statins in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Barts & The London NHS Trust
National Health Service, United Kingdom

Completed

Trial of Vitamin D Supplementation in Chronic Obstructive Pulmonary Disease (ViDiCO)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca
Quintiles, Inc.

Terminated

A Study to Assess Safety, Tolerability and Pharmacokinetics of of AZD6553 in Healthy Volunteers and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Baylor College of Medicine
Michael E. DeBakey VA Medical Center

Recruiting

Accessing Mobility Using Wearable Sensors

Cardiovascular Diseases | Pulmonary Disease | COPD | Congestive Heart Failure | Pulmonary Restrictive Disease

United States
Respivert Ltd

Completed

Safety, Tolerability and Pharmacokinetics (PK) of RV1162 in Healthy Subjects and COPD Patients

Healthy Volunteers | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Pulmatrix Inc.
Quotient Clinical

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of PUR0200 in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Maya Guglin

Terminated

Sildenafil in Heart Failure With Reactive Pulmonary Hypertension (Sildenafil-HF)

Heart Failure With Reactive Pulmonary Hypertension

United States
Imperial College London

Completed

Acute Effects of a Flutter Device in COPD (AEFLUC)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Effect of Multiple Dosing With AZD 4721 and/or With AZD 5069

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
NHS Greater Glasgow and Clyde

Withdrawn

Replacement of Nebulised Ipratropium With Inhaled Tiotropium in Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome

Idiopathic Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United Kingdom
University of Florida
National Institute of General Medical Sciences (NIGMS)

Terminated

Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure

Pulmonary Hypertension | Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure

United States
Chiesi Farmaceutici S.p.A.

Completed

Evaluation of the Absolute Bioavailability and Mass Balance of CHF6001 (Tanimilast) in Healthy Subjects

Chronic Obstructive Pulmonary Disease (COPD) | COPD

United Kingdom

Clinical Trials on Pulmonary Failure in United Kingdom

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