Clinical Trials on RAS Mutation

Total 2550 results

Heidelberg University

Unknown

Relevance of Biomarkers in the Process of Weaning

Duration of Weaning

Germany
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Rapid Pancreatic and Ovarian Screening MR Imaging With Motion Corrected T1, T2, and Advanced Diffusion Weighted Imaging for Patients With BRCA Mutation Who Undergo Screening Breast MRI

Screening Breast MRI in Patients Who Are BRCA Mutation Carriers

United States
Baodong Qin

Unknown

Effect of Chemotherapy on TMB in NSCLC

Chemotherapy Effect | Immunotherapy | Tumor Mutation Burden | PD-1/L1 Inhibitor

China
Centre Hospitalier Universitaire de Nīmes

Completed

Asymmetry of the Center of Pressure During Gait After Amputation of Lower Limbs (ASCOPALL)

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury)

France
Minneapolis Veterans Affairs Medical Center
United States Department of Defense

Completed

Women's-Specific Footwear With Prosthetic Feet (WSF)

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury)

United States
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy and Safety of Voretigene Neparvovec in Japanese Patients With Biallelic RPE65 Mutation-associated Retinal Dystrophy

Biallelic RPE65 Mutation-associated Retinal Dystrophy

Japan
Eloxx Pharmaceuticals, Inc.
SGS Life Sciences, a division of SGS Belgium NV

Completed

Phase 1 Study of ELX-02 in Healthy Adults

Genetic Disease | Nonsense Mutation

Belgium
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Study of ZG19018 in Patients With KRAS G12C Mutant Advanced Solid Tumors.

KRAS G12C Mutant Advanced Solid Tumors

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Phase I Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Advanced KRAS G12D Mutant Solid Tumors

China
Amgen

Active, not recruiting

A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

KRAS p.G12C Mutant Advanced Solid Tumors

United States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
Universitair Ziekenhuis Brussel

Completed

Comparison of 2 Depth of Sedation Indices in the Intensive Care Unit (PSIWAV)

Deep Sedation | Post-cardiac Surgery | RASS-score

Belgium
Weibing Tang

Completed

Assessment of Enhanced Recovery After Surgery Implementation at Pediatric Surgery Practices in Mainland China

ERAS

China
Ciusss de L'Est de l'Île de Montréal

Completed

Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption (KETABIS)

Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption

Canada
University of Aarhus
Aarhus University Hospital

Completed

Evaluation of Mobile X-ray Within the Triple Aim Method

Patient Satisfaction | X-rays; Effects | Health Impairment

Denmark
Assuta Medical Center

Completed

The Use of X-ray in Bariatric Surgeries

X-rays; Effects | Complications of Bariatric Procedures

Israel
Sebastian Bauer
Hannover Medical School; University Hospital Tuebingen; Universitätsmedizin Mannheim and other collaborators

Unknown

POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST (POETIG)

GIST, Malignant | KIT Gene Mutation | KIT Exon 13 Mutation

Germany
Aarhus University Hospital

Completed

Reconstruction of the Medial Patellofemoral Ligament - A Randomised Controlled Trial Comparing Two Surgery Technics

Knee Stability | Patella Luxation

Denmark
University of Michigan
United States Department of Defense

Recruiting

Regenerative Peripheral Nerve Interfaces for the Control of Above-knee Prostheses

Amputation | Prostheses and Implants

United States
Dokuz Eylul University

Not yet recruiting

Comparison of Immediate Effects of Different Shoulder Stretching Techniques in Overhead Athletes

Glenohumeral Internal Rotation Deficit
Hacettepe University

Active, not recruiting

The Dynamic Postural Changes in Transtibial and Transfemoral Amputees

Amputation | Balance | EMG | Perturbation

Turkey
Akdeniz University

Completed

The Impact of Estrogen Administration Duration in Hormonally Prepared Frozen Embryo Transfer Cycles

Duration of Estrogen Administration

Turkey
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Liberating Technologies, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Functional Outcomes of Voice Recognition Prosthesis

Amputation | Prosthesis | Prosthesis User

United States
University of South Florida
U.S. Army Medical Research and Development Command; Telemedicine & Advanced...

Completed

Virtual Reality Prosthetic Training and Rehabilitation

Amputation of Upper Limb

United States
Sheba Medical Center

Completed

Evaluation of the Efficiency of the Echelon Foot in Traumatic Trans Tibial Amputees

Unilateral Trans Tibial Amputation

Israel
The Cleveland Clinic

Terminated

The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine

Duration of Interscalene Block

United States
Indiana University
United States Department of Defense; University of Notre Dame

Completed

Limb Health and Socket Pressure in Response to Powered Ankle Protheses (OPORP)

Amputation | Prosthesis User | Mobility Limitation | Pressure Ulcer, Ankle | Prosthesis Durability | Skin Wound | Amputation; Traumatic, Foot | Limb Deficiencies

United States
Pfizer

Recruiting

Special Investigation for VIZIMPRO Tablets (Secondary Data Collection Study; Safety and Efficacy of VIZIMPRO Under Japanese Medical Practice)

EGFR Mutation-positive Inoperable or Reccrent NSCLC

Japan
Suzhou Genhouse Bio Co., Ltd.
Zhejiang Cancer Hospital

Not yet recruiting

GH21 Combined With D-1553 With Advanced Solid Tumors

KRAS G12C Mutant Solid Tumors
Central Hospital, Nancy, France

Not yet recruiting

Interventional Reference Levels (IRL) in Digestive Endoscopy (EndoscopX)

Each Endoscopic Intervention Using X-rays

France
Yonsei University

Completed

Feasibility of AI-based Heart Function Prediction Model Using CXR (AI-CXR)

Chest X-ray for Clinical Evaluation

Korea, Republic of
Centre Hospitalier Universitaire Vaudois
Swiss National Science Foundation

Completed

Interaction Between a Calcimimetic Agent and the Renin Angiotensine Aldosterone System

Relationship Between Calcimimetic and the RAAS

Switzerland
HaEmek Medical Center, Israel

Completed

Preparative Fasting Before Contrast-enhanced Computed Tomography

X-ray Contrast Media Adverse Reaction

Israel
Xijing Hospital

Unknown

Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy

Disorder of Blood Gas | Bypass Complications

China
Lawson Health Research Institute

Not yet recruiting

Patient Reported Outcomes Targeting Early Chest Tube Removal (PROTECTR) Study (PROTECTR)

Chest Tube Removal | Lung Surgery | ERAS

Canada
Reto Sutter, MD

Not yet recruiting

Photon Counting Detector CT Image Quality

Diagnostic Imaging | Tomography, X Ray Computed
Providence Health & Services

Available

Intermediate-size IND for Treatment of KRAS G12V-mutant Tumors

KRAS G12V Mutant Advanced Epithelial Cancers
The University of Texas Health Science Center,...
Samsung Electronics

Completed

Validation of a New Post Image Processing Engine (S-Vue™) for the Reduction of Ionizing Radiation Dose on X-ray Examination in Pediatric Patients

Chest X-ray for Clinical Evaluation

United States
University Hospital, Brest

Completed

Comparative Study of Calculating the X-ray Dose to the Skin of the Patient Exposed (DOSEMAP)

Measure of the X-ray Dose

France
Karolinska Institutet

Completed

A Pilot Validation Study of Continuous CO2-based End-expiratory Lung Volume Measurements in Humans. (ELVIS)

Pulmonary Function | Ventilator Lung | Gas Exchange

Sweden
Konkuk University Medical Center

Completed

Propofol Induction's Effect on Cardiac Function

This Study Was Focused to Evaluate Feasibility of Doppler Tissue Monitoring During the Induction Anesthesia, | and Evaluate Routine Propofol Induction's Effect on Myocardial Tissue Motion, Using Non-invasive Doppler Tissue and 2D Speckle Tracking Imaging. | This is the First Study,...

Korea, Republic of
AstraZeneca

Completed

To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.

HER2-ve Metastatic Breast Cancer | Germline BRCA1/2 Mutations | Somatic BRCA1/2 Mutations

Italy, Spain, Poland, Taiwan, Canada, France, Germany, Korea, Republic of, Hungary, Japan, Russian Federation, Turkey, United Kingdom, United States, Bulgaria
Bayer

Recruiting

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Verastem, Inc.
Mirati Therapeutics Inc.

Recruiting

Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients (RAMP204)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung | Malignant Neoplastic Disease | KRAS Activating Mutation

United States
Stanford University

Completed

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | KRAS Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Investigation of Southern Tick-Associated Rash Illness (STARI)

Southern Tick-Associated Rash Illness

United States
Sensorion

Recruiting

Natural History in Children up to 10 Years With Moderate to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes (Otoconex)

Sensorineural Hearing Loss, Bilateral | Congenital Deafness | AUNB1 | DFNB1A | DFNB9 | OTOF Gene Mutation | GJB2 Gene Mutation

France
Bayer

Recruiting

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Hong Kong, United States, Taiwan, Spain, Belgium, China, Japan, France, Korea, Republic of, Singapore, Poland, Israel, Italy, Netherlands, Portugal, Brazil
Bayer

Completed

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
GenoSaber
Sun Yat-sen University; Shanghai Chest Hospital; Shanghai Pulmonary Hospital,...

Unknown

Human EGFR Mutations Quantitative Detection Kit (Real-time Fluorescent PCR Method)

Non Small Cell Lung Cancer | EGFR-TKI Resistant Mutation | EGFR-TKI Sensitizing Mutation

Clinical Trials on RAS Mutation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Taiwan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations