Clinical Trials on Rectal Cancer

Total 126913 results

Fujian Cancer Hospital

Not yet recruiting

A Phase II Multicenter Clinical Study of Improved Short-course Radiotherapy Combined With CAPOX and PD-1 Monoclonal Antibody for Locally Advanced Mid-low Rectal Cancer

Mid-low Rectal Cancer
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
Sun Yat-sen University
Akeso; Haplox Biotechnology Co., Ltd.

Recruiting

Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Peking Union Medical College Hospital

Not yet recruiting

TIME in Immunotherapy Combined With nCRT for Rectal Cancer (TIMENT-R)

Locally Advanced Rectal Cancer
Beijing Friendship Hospital
Peking University First Hospital; Peking University People's Hospital; Peking... and other collaborators

Recruiting

Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer (POLAR-STAR)

Locally Advanced Rectal Cancer

China
Zhejiang Cancer Hospital

Recruiting

Dendrobium Huoshanense Suppository in Rectal Cancer

Locally Advanced Rectal Cancer

China
Istanbul Training and Research Hospital

Recruiting

The Role of Vitamin D in Predicting Response to Neoadjuvant Therapy in Patients With Rectal Cancer

Rectal Cancer | Stage III Rectal Cancer

Turkey
Fundación para el Fomento de la Investigación Sanitaria...
Hospital General Universitario Elche

Recruiting

Organ Preservation in Locally Advanced Rectal Cancer (PRONAR)

LOCALLY ADVANCED RECTAL CANCER

Spain
Sir Mortimer B. Davis - Jewish General Hospital

Recruiting

No Surgery Trial / Two Dose-escalation Strategies (Morpheus)

Stage II Rectal Cancer

Canada
Gruppo Oncologico del Nord-Ovest

Active, not recruiting

Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 (ShorTrip)

Locally Advanced Rectal Cancer

Italy
University Medical Center Goettingen
German Research Foundation

Active, not recruiting

Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC-II-IV, With a 5-Fluorouracil-based Standard Radiochemotherapy Followed by Total Mesorectal Excision. (TransValid-A)

Locally Advanced Rectal Cancer

Germany
Hospital Pedro Hispano

Completed

Evaluation of Inflammatory Markers in LARC Patients

Locally Advanced Rectal Cancer
Cancer Trials Ireland

Terminated

Pre-operative 3-DCRT vs IMRT for Locally Advanced Rectal Cancer (TRI-LARC)

Locally Advanced Rectal Cancer

Ireland
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Locally Advanced Rectal Cancer

United States, Spain
First Affiliated Hospital of Zhejiang University

Unknown

Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Sun Ying-Shi

Completed

Predicting Pathological Complete Response of Rectal Cancer With Magnetic Resonance(MR) Radiomics

Locally Advanced Rectal Cancer

China
Fudan University

Unknown

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Michelle Mossa
University of Liverpool

Completed

The Effect of Cancer Therapies and Exercise on Mitochondrial Energetics and Fitness

Locally Advanced Rectal Cancer

United Kingdom
Institute of Oncology Ljubljana

Unknown

Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study (CRAB)

Locally Advanced Rectal Cancer

Slovenia
Takayuki Yoshino
Ono Pharmaceutical Co. Ltd

Recruiting

Study to Nivolumab Following Preoperative Chemoradiotherapy

Cancer of Rectum

Japan
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Unresectable Colon Adenocarcinoma | Unresectable Rectal Adenocarcinoma

United States, Puerto Rico
Johns Hopkins Bloomberg School of Public Health
Centers for Medicare and Medicaid Services

Completed

Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial (CPTD)

Breast Cancer | Lung Cancer | Prostate Cancer | Cervix Cancer | Colon Cancer | Rectum Cancer

United States
Maimónides Biomedical Research Institute of Córdoba
Reina Sofia University Hospital; Consejería de Salud (Junta de Andalucía)

Unknown

Gut Microbiota and Color-rectal Cancer. (CCR-microbiota)

Cancer | Diagnoses Disease | Colo-rectal Cancer | Intestinal Disease | Microbiota-related Disease

Spain
Sofya Pintova
DSM Nutritional Products, Inc.

Completed

Genistein in Treatment of Metastatic Colorectal Cancer

Colorectal Cancer | Rectal Cancer | Colon Cancer

United States
Wuhan Union Hospital, China
Renmin Hospital of Wuhan University

Recruiting

Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study

Locally Advanced Rectal Cancer

China
Beijing Friendship Hospital
Peking Union Medical College Hospital

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
JIN JING

Not yet recruiting

Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13） (AK104-IIT-13)

Locally Advanced Rectal Cancer
National Cancer Center Hospital East
Japan Agency for Medical Research and Development

Recruiting

Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE) (ENSEMBLE)

Locally Advanced Rectal Cancer

Japan
Fudan University

Recruiting

The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer (TORCH-E） (TORCH-E)

Early Low Rectal Cancer

China
Korean Cancer Study Group

Not yet recruiting

Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer
Yonsei University

Not yet recruiting

Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients

Locally Advanced Rectal Cancer

Korea, Republic of
Fudan University

Recruiting

Short-course Radiotherapy Based TNT Combined With PD-1 Inhibitor for Locally Advanced Rectal Cancer (TORCH)

Locally Advanced Rectal Cancer

China
Montreal General Hospital

Recruiting

The Impact of Physical Exercise on Sleep in Colorectal Cancer Patients During Prehabilitation Period

Surgery | Colo-rectal Cancer

Canada
Thomas Jefferson University

Completed

Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?

Anesthesia | Colo-rectal Cancer

United States
Prof. Dr. med. Claus Rödel

Active, not recruiting

Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Rectal Cancer Stage III

Germany
Universitätsklinikum Hamburg-Eppendorf
Servier Affaires Médicales; Clinical Trial Center North (CTC North GmbH & Co...

Terminated

Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

Locally Advanced Rectal Cancer

Germany
Taichung Veterans General Hospital

Completed

Using Artificial Intelligence to Predict Rectal Cancer Outcomes

Rectal Cancer Stage III

Taiwan
Fudan University

Unknown

A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Thomas Zilli
University Hospital, Geneva

Terminated

Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy

Rectal Cancer | Advanced Cancer | Rectal Tumors

Switzerland
RenJi Hospital

Active, not recruiting

Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer

Rectal Cancer Stage III

China
Zhu Ji

Unknown

Tumor Response Prediction in Neoadjuvant Chemoradiation of Locally Advanced Rectal Cancer Using Metabonomics Analysis

Locally Advanced Rectal Cancer

China
Maastricht University Medical Center

Completed

Minimal Invasive Strategies for Good and Complete Response to Chemoradiation in Rectal Cancer

Locally Advanced Rectal Cancer

Netherlands
Zhejiang Cancer Hospital

Unknown

Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Completed

Quality of Life After Rectal Cancer Surgery

Quality of Life | Rectal Cancer

Turkey
The Cleveland Clinic

Completed

Quality of Life in Patients That Undergo J Pouch or Side to End Coloanal Anastomosis for Rectal Cancer

Rectal Cancer

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

A Questionnaire to Assess the Quality of Life of Rectal Cancer Patients With or Without Stoma

Rectal Cancer

Italy
Nanfang Hospital of Southern Medical University

Completed

Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer

Erectile Dysfunction | Rectal Tumors

China
Amgen

Completed

Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment (PRECEPT)

Cancer | Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Metastatic Cancer | Colon Cancer | Oncology
Federation Francophone de Cancerologie Digestive

Withdrawn

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Colorectal Cancer | Metastatic Cancer

France
University of California, San Francisco

Completed

Self-monitoring and Reminder Texts to Increase Physical Activity After Cancer II (SmartPaceII)

Colorectal Cancer | Rectal Cancer | Colon Cancer

United States

Clinical Trials on Rectal Cancer

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