Clinical Trials on Radiation; Adverse Effect, Pneumonitis in Canada

Total 82 results

CHU de Quebec-Universite Laval

Terminated

Efficacy of Trans-tympanic Injections of a Sodium Thiosulfate Gel to Prevent Cisplatin-induced Ototoxicity (STS001)

Head and Neck Cancer | Adverse Effect | DDP

Canada
Centre hospitalier de l'Université de Montréal...
Varian Medical Systems

Completed

Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.

Lung Cancer | Radiation Pneumonitis | Lung Function Decreased

Canada
Maisonneuve-Rosemont Hospital
Université de Montréal

Completed

Impact of Noise on Anesthesiologists' and Trainees' Situational Awareness in a High Fidelity Simulation Environment

Noise; Adverse Effect

Canada
Ultromics Ltd
Mazankowski Alberta Heart Institute

Enrolling by invitation

Mazankowski Alberta Heart Institute (MAHI) EchoGo Discovery 1 Protocol

Cancer | Cardiotoxicity

Canada
University Health Network, Toronto

Active, not recruiting

The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Pilot Study (HIMALAYAS-P)

Heart Failure | Cancer | Cardiotoxicity

Canada
University Health Network, Toronto
Sunnybrook Health Sciences Centre; Unity Health Toronto; Mount Sinai Hospital... and other collaborators

Active, not recruiting

Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study (SPARE-HF)

Heart Failure | Cancer | Cardiotoxicity

Canada
Ottawa Hospital Research Institute
McGill University; Canadian Institutes of Health Research (CIHR)

Completed

Information Systems-enabled Outreach Program for Adverse Drug Events (ISTOP-ADE)

Adverse Drug Events

Canada
Mayo Clinic
St. Boniface Hospital; Lantheus Medical Imaging; The Asper Foundation

Completed

Early Detection of Broken Hearts in Cancer Patients (ASPER)

Cardiotoxicity

United States, Canada
Westview Physician Collaborative

Completed

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

Adverse Drug Events

Canada
McGill University Health Centre/Research Institute...

Unknown

PhysioFlow to Detect Cardiotoxicity in Chemo (PULSE-ECCho)

Chemotherapy, Cancer, Cardiotoxicity, Physioflow

Canada
University Health Network, Toronto
University of British Columbia; Alberta Health services; University of Alberta; Centre hospitalier de l'Université de Montréal (CHUM) and other collaborators

Recruiting

The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial (HIMALAYAS)

Heart Failure | Cancer | Cardiotoxicity

Canada
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Using Novel Canadian Resources to Improve Medication Reconciliation at Discharge

Adverse Drug Events | Medication Reconciliation

Canada
Lawson Health Research Institute

Completed

A Prospective Study to Assess Metabolic Changes in Children and Adolescents Treated With Atypical Antipsychotics

Adverse Effects

Canada
St. Boniface Hospital

Unknown

Can Flaxseed Prevent Broken Hearts in Women With Breast Cancer Study? (CANFLAX)

Cardiotoxicity

Canada
St. Justine's Hospital
CIUSSS du Nord-de-l'Île-de-Montréal

Recruiting

Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population (MEMAS)

Adverse Drug Event

Canada
AHS Cancer Control Alberta
Cross Cancer Institute

Unknown

Study to See Whether Breath-Hold Techniques During RT Are Effective in Helping to Improve Sparing of the Heart

Breast Cancer | Adverse Effect of Radiation Therapy

Canada
University of British Columbia
Icahn School of Medicine at Mount Sinai; Vancouver Coastal Health

Unknown

Adverse Events and Genomics in Schizophrenia (AEGIS)

Adverse Effect of Other Antipsychotics and Neuroleptics

Canada
Massachusetts General Hospital
Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)

Heart Failure

United States, Canada
University of British Columbia
Genome British Columbia; Genome Canada; Dynacare Laboratories, Inc.

Recruiting

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Adverse Drug Reaction (ADR)

Canada
Sunnybrook Health Sciences Centre

Completed

Thermal Imaging to Evaluate Skin Toxicity From Radiotherapy

Radiodermatitis | Radiotherapy Side Effect

Canada
McGill University Health Centre/Research Institute...
Centre for Aging and Brain Health Innovation; MED e-care Healthcare Solutions; OMNI Health Care

Withdrawn

MedSafer E-care: an Automated Deprescribing Solution (E-CARE Study) (E-CARE)

Deprescribing | Polypharmacy | Adverse Drug Event

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); London Health Sciences Centre; Children's Hospital of Eastern Ontario and other collaborators

Completed

Preventing Cardiac Sequelae in Pediatric Cancer Survivors (PCS2)

Anthracycline-induced Cardiotoxicity

United States, Canada
Children's Hospital of Eastern Ontario
The Hospital for Sick Children; Ottawa Hospital Research Institute; London Health... and other collaborators

Completed

How Safe Are Our Pediatric Emergency Departments?

Adverse Effects | Adverse Drug Event

Canada
Lawson Health Research Institute

Completed

CYP2D6 Screening for Adverse Drug Reactions to Codeine in Breast Milk

Cytochrome P450 2D6 Ultra-rapid Metabolism

Canada
University Health Network, Toronto

Unknown

Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?

Hearing Loss | Ototoxicity

Canada
AHS Cancer Control Alberta

Terminated

Novel Surrogate Markers as Predictors of Radiation Toxicity in Breast Cancer Patients Undergoing Helical Tomotherapy Compared to Standard Radiation Therapy

Cardiac Toxicity | Genetic Markers | Breast and Skin Motion

Canada
Nova Scotia Health Authority

Completed

Exercise to Prevent AnthrCycline-based Cardio-Toxicity Study (EXACT)

Neoplasms | Inflammation | Heart; Disease, Functional

Canada
Centre for Innovation and Research in Aging, Canada
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Unknown

Spread and Scale of a Polypharmacy App

Deprescribing | Polypharmacy | Adverse Drug Event

Canada
McGill University Health Centre/Research Institute...

Unknown

Transtympanic Ringer's Lactate for the Prevention of Cisplatin Ototoxicity

Hearing Loss

Canada
Sunnybrook Health Sciences Centre

Recruiting

Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy

Ototoxic Hearing Loss

Canada
University Health Network, Toronto

Completed

The Effect of a New Supraglottic Airway With Built-in Cuff Pressure Indicator

The Study Focuses on the Effect of a New Supraglottic Airway With Built-in Cuff Pressure Indicator on Postoperative Pharyngolaryngeal Adverse Events

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg

Sarcoma | Lymphedema | Radiation Toxicity | Radiation Fibrosis | Musculoskeletal Complications

United States, Canada
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
University of British Columbia

Completed

The Effect of Medication Review in High-risk Emergency Department Patients

Adverse Drug Events | Adverse Drug Reactions | Medication-related Problems

Canada
Sunnybrook Health Sciences Centre
London Regional Cancer Program, Canada; Toronto Sunnybrook Regional Cancer...

Recruiting

Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Ototoxic Hearing Loss

Canada
University of Calgary

Terminated

Assessment of Cardiotoxicity After Chemotherapy for Breast Cancer by Cardio-vascular Magnetic Resonance (MR) (Cardiotox)

Breast Cancer

Canada
McGill University Health Centre/Research Institute...
University Health Network, Toronto; University of British Columbia; Canadian... and other collaborators

Completed

Reducing Post-discharge Adverse Drug Events Amongst the Elderly: a Multi-centre Electronic Deprescribing Intervention

Adverse Drug Event

Canada
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
Advanced Accelerator Applications

Terminated

99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer

Breast Cancer | Doxorubicin Induced Cardiomyopathy

Canada
University of Calgary
Alberta Health services; Hotchkiss Brain Institute, University of Calgary

Recruiting

Pharmacogenetics of Antidepressant-Induced Disinhibition (PGx-AID)

Obsessive-Compulsive Disorder | Anxiety Disorders | Major Depressive Disorder | Antidepressant Drug Adverse Reaction

Canada
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS)

Recruiting

Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) (EXACT 2)

Cardiovascular Diseases | Cardiotoxicity | Cancer, Breast

Canada
St. Joseph's Healthcare Hamilton
Canadian Institutes of Health Research (CIHR)

Recruiting

Improving Medication Prescribing-Related Outcomes for Vulnerable Elderly In Transitions (IMPROVE-IT)

Drug-Related Side Effects and Adverse Reactions | Aged | Health Care Costs | Patient Discharge

Canada
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
Lawson Health Research Institute
University of Western Ontario, Canada

Unknown

Is There an Adverse Drug Reaction Between Renin-Angiotensin System Blockade and Inhaled Anesthetics

Hypertension

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); MSH-UHN AMO Innovation Fund

Terminated

Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity (CORE)

Breast Cancer | Heart Failure, Systolic | Left Ventricular Dysfunction

Canada
CHU de Quebec-Universite Laval

Unknown

Amoxicillin Challenge for Penicillin Allergy Diagnosis (Pen-VIE)

Penicillin Allergy

Canada
Unity Health Toronto
Hoffmann-La Roche

Unknown

Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic)

Canada

Clinical Trials on Radiation; Adverse Effect, Pneumonitis in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations