Clinical Trials on Radiation in South Africa

Total 49 results

National Baromedical Services

Terminated

Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries

Radiation Injuries

United States, Australia, Mexico, South Africa, Turkey
Medical University of South Carolina

Completed

Tin Filter Calcium Scoring

Radiation Dose Reduction

United States
Stratpharma AG

Completed

StrataXRT vs. Standard Clinical Practice in the Prevention and Treatment of Radiation Dermatitis

Radiation Dermatitis

Australia
Sanford Health

Completed

Study of Topical Superoxide Dismutase to Treat Radiation Induced Fibrosis (Sodermix)

Radiation Induced Fibrosis to the Head and Neck

United States
University of Sydney
Western Sydney Local Health District

Active, not recruiting

Collection of Head Images During Radiotherapy (CHIRP)

Head and Neck Neoplasms | Radiation Therapy Complication

Australia
University of Aarhus
Aarhus University Hospital; Westmead and Blacktown Hospital, Sydney West Radiation...

Recruiting

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer (ASPECT)

Lung Cancer | Pulmonary Disease | Radiation Pneumonitis | Lung Function Decreased | Radiation-Induced Disorder

Australia, Denmark
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 Lotion in Patients at Risk for Radiation Dermatitis - PRIMROSE

Breast Cancer

United States
Wake Forest University Health Sciences

Completed

Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer (ACUPUNCTURE)

Head and Neck Cancer | Radiation Toxicity | Radiation-Induced Xerostomia | Oral Complications of Chemotherapy and Head/Neck Radiation

United States
University of Sydney
Western Sydney Local Health District

Recruiting

Surface Monitoring Technology to Remove The Mask - Stage 1 (SMART)

Head and Neck Cancer | Anxiety | Radiation Therapy Complication

Australia
North Central Cancer Treatment Group
National Cancer Institute (NCI)

Completed

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

Breast Cancer | Radiation Toxicity | Skin Reactions Secondary to Radiation Therapy | Dermatologic Complications

United States
Eli Lilly and Company

Completed

Duloxetine Versus Placebo in Chronic Low Back Pain

Back Pain Without Radiation

United States
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Terminated

Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy

Lung Cancer | Pulmonary Complications | Radiation Fibrosis

United States
Sound Pharmaceuticals, Incorporated
Medical University of South Carolina; Cystic Fibrosis Foundation

Enrolling by invitation

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Ototoxicity

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Brain and Central Nervous System Tumors | Radiation Toxicity

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; National Institutes of Health... and other collaborators

Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy (AL)

Visual Impairment | Radiation Retinopathy

United States
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy

Head and Neck Cancer | Radiation Toxicity

United States
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
Galera Therapeutics, Inc.

Completed

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Radiation Induced Oral Mucositis

United States, Canada, Puerto Rico
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy

Diarrhea | Radiation Enteritis

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy in Treating Patients With Prostate Cancer

Sexual Dysfunction | Prostate Cancer | Radiation Toxicity | Psychosocial Effects of Cancer and Its Treatment

United States, Canada
Royal Prince Alfred Hospital, Sydney, Australia

Completed

Cardiotoxicity of Adjuvant Trastuzumab (CATS)

Heart Failure | Breast Neoplasms

Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States, Canada
Ortho-McNeil Janssen Scientific Affairs, LLC
Grünenthal GmbH

Completed

NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain

Pain | Back Pain | Low Back Pain | Back Pain With Radiation

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

Skin Angiosarcoma | Skin Radiation-Related Angiosarcoma | Visceral Angiosarcoma

United States, Guam
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

Head and Neck Cancer | Skin Reactions Secondary to Radiation Therapy

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States, Canada, Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Perioperative/Postoperative Complications | Gastrointestinal Complications | Urinary Complications | Urinary Tract Toxicity

United States, Canada, Singapore, Hong Kong
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Radiation Toxicity

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

Unspecified Childhood Solid Tumor, Protocol Specific | Ototoxicity

Canada, United States, Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Chemotherapeutic Agent Toxicity

United States, Israel
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Cancer and Leukemia Group B; North...

Completed

High-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Cancer | Radiation Toxicity

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer

Depression | Delirium | Lung Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab

Breast Cancer | Cardiac Toxicity

United States
Daiichi Sankyo, Inc.

Completed

Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

SWOG-9342 Chemotherapy in Treating Women Enrolled in the SWOG-8897 Clinical Trial

Breast Cancer | Cardiac Toxicity

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Canada, Switzerland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Lung Cancer | Radiation Toxicity | Drug/Agent Toxicity by Tissue/Organ

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Pain | Head and Neck Cancer | Mucositis | Oral Complications of Radiation Therapy

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

Lung Cancer | Radiation Toxicity | Oral Complications | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

Cardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7

United States, Korea, Republic of, Puerto Rico, Saudi Arabia
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Sarcoma | Ovarian Cancer | Brain Tumor | Ototoxicity | Neuroblastoma | Liver Cancer | Central Nervous System Tumor | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Canada, United States, Australia

Clinical Trials on Radiation in South Africa

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CROs by country

CROs in Vietnam

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