Clinical Trials on Radiation Toxicity

Total 1685 results

McGill University Health Centre/Research Institute...

Unknown

PhysioFlow to Detect Cardiotoxicity in Chemo (PULSE-ECCho)

Chemotherapy, Cancer, Cardiotoxicity, Physioflow

Canada
Instituto de Cardiologia do Rio Grande do Sul
Hospital Ernesto Dornelles

Completed

Transradial and Transfemoral Coronary Angiography by EXPERienced operaTors (EXPERT)

Coronary Heart Disease | Vascular Access Complication | Exposure to Ionizing Radiation

Brazil
ProCertus BioPharm, Inc
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy

Alopecia | Radiodermatitis

United States
Ziv Hospital

Unknown

Intratympanic Steroid Treatment For The Prevention Of Inner Ear Toxicity Associated With Systemic Treatment With Cisplatin.

Ototoxicity | Cisplatin | Intratympanic Steroids

Israel
Instituto de Assistencia Medica ao Servidor Publico...
University of Sao Paulo; Federal University of São Paulo; Hospital Padre Albino...

Completed

Multi-center Trial of Goal-directed Fluid Management Based on Pulse Pressure Variation Monitoring (GDTPPV)

Postoperative Complications | Hemodynamics Instability | Goal-directed Fluid Therapy | High-risk Surgery | Pulse-pressure Variation
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

Lung Non-Squamous Non-Small Cell Carcinoma | Stage II Lung Non-Small Cell Cancer AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV... and other conditions

United States
Cedars-Sinai Medical Center
Jarrow Formulas Inc

Not yet recruiting

SAMe in Prevention of Oxaliplatin-associated Liver Injury

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Liver Injury | Sinusoidal Obstruction Syndrome | 5-Fluorouracil Toxicity | Liver Toxicity, Chemically-Induced

United States
British Columbia Cancer Agency

Unknown

Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy

Arthralgia | Myalgia | Invasive Breast Cancer | Chemotherapeutic Toxicity
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
European Institute of Oncology

Recruiting

Myocardial Fibrosis Identification in Patients With Anthracycline-induced Cardiotoxicity

Cardiomyopathy Due to Drug

Italy
University of Sao Paulo

Not yet recruiting

Effect of Spironolactone in the Prevention of Anthracycline-induced Cardiotoxicity (SPIROTOX) (SPIROTOX)

Heart Failure | Neoplasms | Chemotherapy Effect | Cardiotoxicity

Brazil
Cardiology Prague
BioVendor LM; Oncology Center Medicon

Recruiting

New Biomarkers in the Prediction of Chemotherapy-induced Cardiotoxicity.

Chemotherapy Effect | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Czechia
Oncology Institute of Southern Switzerland
Cardiocentro Ticino; North Estonia Medical Centre; Fondazione IRCCS Policlinico...

Recruiting

Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Breast Cancer Patients (CARDIOTOX)

Cardiotoxicity

Switzerland
Peking University Third Hospital
Huashan Hospital; Tianjin Medical University

Completed

Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases in NSCLC (AnloSBRT)

Stereotactic Body Radiation Therapy

China
Peking University Cancer Hospital & Institute

Unknown

Early Diagnosis of Therapy-associated Cardiotoxicity Basing on Multi-tracer Multimodality PET/MRI

Magnetic Resonance Imaging | Positron-Emission Tomography

China
Shandong University

Unknown

Optimal Duration of Antimicrobial Susceptibility Test (AST) Guided Rescue Therapy for Helicobacter Pylori Infection

Helicobacter Pylori | Eradication | Therapeutic Duration | Antimicrobial Susceptibility Test
Erasmus Medical Center

Recruiting

Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial

Immunotherapy | Melanoma Stage IV | Melanoma Stage III | Toxicity, Drug

Netherlands
Leiden University
Bristol-Myers Squibb

Active, not recruiting

TIL and Anti-PD1 in Metastatic Melanoma (ACTME)

Effects of Immunotherapy | Adverse Drug Event | Toxicity, Drug

Netherlands
Medical University of Vienna

Completed

Heavy Metals, Angiogenesis Factors and Osteopontin in Coronary Artery Disease (CAD)

Coronary Artery Disease | Ischemic Heart Disease | Heavy Metal Toxicity

Austria
Indiana University
Indiana Clinical and Translational Sciences Institute

Recruiting

Daily Hand-Held Vibration Therapy

Cancer | Neuropathy | Chemotherapeutic Toxicity | Chemotherapeutic Drug - Induced Nephropathy

United States
Instituto Nacional de Cancerologia de Mexico

Recruiting

Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC

Lung Cancer | Sarcopenia | Toxicity

Mexico
Rush University Medical Center

Withdrawn

Pedaling at a Low-Moderate Intensity During Chemotherapy Administration

Colorectal Cancer | Chemotherapy | Chemotherapeutic Toxicity | Exercise, Aerobic

United States
Vanderbilt University Medical Center
National Cancer Institute (NCI)

Completed

Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia

Leukemia | Renal Toxicity

United States
Tanta University

Not yet recruiting

Trimetazidine As a Potential Adjuvant Therapy in Acute Aluminum Phosphide Poisoning-induced Cardiotoxicity

Aluminum Phosphide Poisoning
Beijing 302 Hospital

Recruiting

Comparison of Efficacy in SBRT of HCC ≤5 cm With or Without TACE

Stereotactic Body Radiation Therapy | Transcatheter Arterial Chemoembolization | Small Hepatocellular Carcinoma

China
St. James's Hospital, Ireland
Karolinska Institutet; St Mary's Hospital, Paddington, London

Completed

European iNvestigation of SUrveillance After Resection for Esophageal Cancer (ENSURE)

Esophageal Cancer | Chemoradiation | Chemotherapy | Surgery | Metastatic Cancer | Radiation | Recurrent Esophageal Cancer

Sweden, Ireland, United Kingdom
Peking University Third Hospital
Huashan Hospital; Tianjin Medical University

Unknown

Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC (Rvision-001)

Stereotactic Body Radiation Therapy

China
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine Thorough QT/QTc

Cardiotoxicity

United States
University of Oslo School of Pharmacy

Completed

Investigations on Differences in Atorvastatin Metabolites Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity

Myotoxicity of Atorvastatin Treatment

Norway
University of Wisconsin, Madison
Blue Earth Diagnostics

Recruiting

18F-FLUC-CEST PET/MR in Patients With Brain Mets

Brain Metastasis | Radiation Therapy | Immunotherapy, Active

United States
Ain Shams University

Recruiting

Role of Statin Therapy in Prevention of Anthracycline-Induced Cardiotoxicity

Doxorubicin Induced Cardiomyopathy

Egypt
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
Ju-Chi Liu
Taipei Medical University Hospital; Taipei Medical University WanFang Hospital and other collaborators

Not yet recruiting

Smart Home Care of Cloud Base ECG on the Cardiotoxicity Prevention on the Cancer Patients. (AI)

Cardiotoxicity | ECG | Artificial Intelligent | Cardiac Monitor | Cancer Treatment
UMC Utrecht

Recruiting

EREctile Function Preservation for Prostate Cancer Radiation Therapy (ERECT) (ERECT)

Prostate Cancer | Erectile Dysfunction Following Radiation Therapy

Netherlands
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Cardiotoxicity of Cancer Therapy (CCT)

Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

Unspecified Childhood Solid Tumor, Protocol Specific | Ototoxicity

Canada, United States, Australia
Sheba Medical Center

Unknown

Transforaminal Epidural Steroid Injection With Pulsed Radiofrequency for Chronic Lumbosacral Radicular Pain Management

Low Back Pain | Radicular; Neuropathic, Lumbar, Lumbosacral | Back Pain With Radiation
Sun Yat-sen University
Fifth Affiliated Hospital, Sun Yat-Sen University

Unknown

A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

Brain Metastasis | Radiation Therapy Complication

China
Hospices Civils de Lyon

Completed

Impact of a Mediator for Patient Intake in Emergency Departments (MEDIA)

Violent Aggressive Behavior | Mediation

France
Scripps Health

Completed

Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors

Lymphoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
HealthPartners Institute

Terminated

L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer

Breast Cancer | Neurotoxicity | Chemotherapeutic Agent Toxicity

United States
Mansoura University

Recruiting

Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.

Oral Mucositis (Ulcerative) Due to Radiation

Egypt
West China Hospital

Recruiting

Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Oral Mucositis (Ulcerative) Due to Radiation

China
University Hospital, Montpellier

Recruiting

Prediction of Delayed Toxic Cardiomyopathy in Children (SpeckleAnthra2)

Childhood Cancer | Cardiotoxicity

France
Chinese University of Hong Kong

Not yet recruiting

Evaluating Chinese Medicine Oral Rinse for Irradiated Oral Mucositis in Head & Neck Cancer Patients

Head and Neck Neoplasms | Oral Mucositis (Ulcerative) Due to Radiation | Chinese Medicine Oral Rinse

Hong Kong
Ludwig-Maximilians - University of Munich

Recruiting

Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma (LIVERCARE)

Quality of Life | Hepatocellular Cancer | Stereotactic Body Radiation Therapy | Observational

Germany
Maria Sklodowska-Curie National Research Institute...
Servier; Polish Cardiac Society

Active, not recruiting

Atherosclerosis in Chemotherapy-related Cardiotoxicity (ANTEC)

Atherosclerosis | Cardiotoxicity

Poland
The Hospital for Sick Children

Completed

Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma

Brain Tumor Treated With Cranial or Cranial-Spinal Radiation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
University of Sao Paulo General Hospital
InCor Heart Institute; Hospital Sirio-Libanes; Cancer Institute of Sao Paulo

Unknown

Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment

Heart Failure | Cancer | Cardiotoxicity | Insufficiency;Cardiac

Brazil

Clinical Trials on Radiation Toxicity

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