Clinical Trials on Radiation-Induced Mucositis in South Africa

Total 531 results

Galera Therapeutics, Inc.

Completed

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Radiation Induced Oral Mucositis

United States, Canada, Puerto Rico
Sanford Health

Completed

Study of Topical Superoxide Dismutase to Treat Radiation Induced Fibrosis (Sodermix)

Radiation Induced Fibrosis to the Head and Neck

United States
National Baromedical Services

Terminated

Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries

Radiation Injuries

United States, Australia, Mexico, South Africa, Turkey
University of Cape Town
Medical Research Council, South Africa

Completed

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis (NAC in TB DIH)

Drug-Induced Liver Injury

South Africa
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy

Head and Neck Cancer | Radiation Toxicity

United States
Ibis Reproductive Health
Society of Family Planning; University of Cape Town; Tygerberg Hospital; Safe Abortion...

Completed

Cervical Priming Before Dilation & Evacuation

Abortion, Induced

South Africa
University of Johannesburg
Medical Research Council, South Africa

Enrolling by invitation

Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump

Lead Poisoning | Lead Poison Children

South Africa
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Stellenbosch and other collaborators

Completed

The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology

Fetal Alcohol Spectrum Disorders

South Africa
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Human Sciences... and other collaborators

Active, not recruiting

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

HIV/AIDS | Alcohol Abuse

South Africa
Medical University of South Carolina
National Cancer Institute (NCI)

Completed

Herbal Mouthrinse for Oral Mucositis Study (OM)

Oral Mucositis

United States
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa
University of Aarhus
Aarhus University Hospital; Westmead and Blacktown Hospital, Sydney West Radiation...

Recruiting

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer (ASPECT)

Lung Cancer | Pulmonary Disease | Radiation Pneumonitis | Lung Function Decreased | Radiation-Induced Disorder

Australia, Denmark
Ipas

Terminated

Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa

Abortion, Induced | Abortion, Incomplete

Mexico, South Africa
RTI International
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Medical Research...

Completed

Venue-Based Couples CoOp in South Africa (Couples CoOp)

HIV Infections | Alcoholism

South Africa
Bukwang Pharmaceutical
Contera Pharma ApS

Completed

Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia (LID)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

South Africa
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
Eunice Kennedy Shriver National Institute of Child...
Medical Research Council, South Africa

Completed

Women-Focused HIV Prevention in the Western Cape (WC-WHC)

HIV | Substance Abuse | Violence

South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
Medical University of South Carolina

Completed

Tin Filter Calcium Scoring

Radiation Dose Reduction

United States
University of Cape Town
Medical University of Vienna; University of Washington

Completed

Acid-Base and Point of Care Ultrasound in Severe Preeclampsia

Pre-Eclampsia

South Africa
Wake Forest University Health Sciences

Completed

Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer (ACUPUNCTURE)

Head and Neck Cancer | Radiation Toxicity | Radiation-Induced Xerostomia | Oral Complications of Chemotherapy and Head/Neck Radiation

United States
RTI International
Medical Research Council, South Africa

Recruiting

Couples Health CoOp Plus (CHC+)

HIV | Substance Use | Stigma, Social

South Africa
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

HIV & Drug Abuse Prevention for South African Men

Substance-Related Disorders | Alcoholism | Human Immunodeficiency Virus

South Africa
Stratpharma AG

Completed

StrataXRT vs. Standard Clinical Practice in the Prevention and Treatment of Radiation Dermatitis

Radiation Dermatitis

Australia
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Eclampsia

Eclampsia

South Africa
University of Stellenbosch
Stanley Medical Research Institute

Completed

Ethyl-Eicosapentaenoic Acid and Tardive Dyskinesia

Schizophrenia | Dyskinesia

South Africa
Monopar Therapeutics

Terminated

Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. (VOICE)

Chemoradiotherapy-Induced Severe Oral Mucositis

United States, Spain, Germany, France, Puerto Rico
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
Abcuro, Inc.

Active, not recruiting

A Phase 1 Study of ABC008 in Ascending (Single Ascending Dose/Multiple Ascending Dose) Study in Patients With (IBM)

Inclusion Body Myositis

Australia
University of Stellenbosch
QuitSupport

Completed

Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation

Tobacco Dependence

South Africa
Chemo Mouthpiece

Completed

A Trial Assessing Chemo Mouthpiece Device With Best Supportive Care for Symptoms of Chemotherapy-Induced Oral Mucositis

Oral Mucositis

United States
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
CSL Behring

Terminated

Safety and Efficacy of ALD518 for Reducing Oral Mucositis in Head and Neck Cancer Subjects

Oral Mucositis

United States, Canada, Australia, Germany, Italy, Austria
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
University of California, Los Angeles
University of Stellenbosch; The ELMA Foundation; Philani Maternal Child Health...

Completed

Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa

Depression | HIV Infections | Alcohol Drinking | Alcohol; Harmful Use | HIV/AIDS | Depressive Symptoms | Child Development | Alcohol Use Disorder | Stunting | Child Nutrition Disorders | Child Malnutrition | Birth Weight Less Than 10Th Percentile

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
University of Washington
University of Cape Town

Completed

Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach

Severe Pre-eclampsia | Mild Pre-eclampsia

South Africa, United States
University of Sydney
Western Sydney Local Health District

Active, not recruiting

Collection of Head Images During Radiotherapy (CHIRP)

Head and Neck Neoplasms | Radiation Therapy Complication

Australia
University of Kansas Medical Center
The Perron Institute

Recruiting

Phase III Trial of Sirolimus in IBM

Inclusion Body Myositis

United States, Australia
RTI International
Kheth'Impilo

Completed

Implementation Research for Vulnerable Women in South Africa

HIV | Substance Abuse

United States, South Africa
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Pain | Head and Neck Cancer | Mucositis | Oral Complications of Radiation Therapy

United States
Regeneron Pharmaceuticals

Recruiting

A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP) (OPTIMA)

Fibrodysplasia Ossificans Progressiva

Japan, United States, Korea, Republic of, Spain, France, Australia, United Kingdom, China, Poland, Malaysia, Italy, Finland, Hong Kong, South Africa, Chile, Brazil, Netherlands, Colombia
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
RTI International
University of North Carolina, Chapel Hill

Completed

WHC+ (Women's Health CoOp PLUS)

Sexually Transmitted Diseases | HIV | Substance Abuse | Violence | Victimization | Sexual Risk

United States, South Africa
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United States, Canada
Reata, a wholly owned subsidiary of Biogen
AbbVie

Completed

RTA 408 Lotion in Patients at Risk for Radiation Dermatitis - PRIMROSE

Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy

Acute Oral Mucositis Pain

United States

Clinical Trials on Radiation-Induced Mucositis in South Africa

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