Clinical Trials on Ras-mutated Metastatic Colorectal Cancer
Total 11326 results
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Lupin Ltd.CompletedA Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsNRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsUnited Kingdom, Netherlands, Belgium
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National Cancer Institute, NaplesRecruitingRas-mutated Metastatic Colorectal CancerItaly
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Cancer Institute and Hospital, Chinese Academy...RecruitingBevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutatedChina
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Institut du Cancer de Montpellier - Val d'AurelleCompletedMetastatic Colorectal Cancer Patients With KRAS Mutated TumorsFrance
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European Organisation for Research and Treatment...SanofiWithdrawnColorectal Cancer Metastatic | Liver Metastases | KRAS Mutated Colorectal Cancer
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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Cardiff OncologyPfizerRecruitingMetastatic Colorectal Cancer | CRC | KRAS/NRAS MutationUnited States
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Elicio TherapeuticsRecruitingColorectal Cancer | Pancreatic Ductal Adenocarcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R | KRAS G12V | KRAS G12C | KRAS G12A | KRAS G12S | KRAS G13D | NRAS G12V | NRAS G12C | NRAS G12SUnited States
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI); Calithera Biosciences, IncActive, not recruitingMetastatic Colorectal Cancer | Colorectal Cancer | RAS Wild Type Colorectal Cancer | Refractory Colorectal CancerUnited States
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Henan Cancer HospitalCompletedWild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
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MapKure, LLCRecruitingColorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal CancersUnited States
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Azienda Unità Sanitaria Locale Reggio EmiliaIstituto Di Ricerche Farmacologiche Mario Negri; Istituto Nazionale Tumori...RecruitingMetastatic Colorectal Cancer | Colorectal Cancer | RAS MutationItaly
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iOMEDICO AGAmgenCompletedMetastatic Colorectal Cancer | RAS Wild-typeGermany
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AmgenCompletedWild-type RAS Metastatic Colorectal Cancer
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University of Campania "Luigi Vanvitelli"CompletedMetastatic Colorectal Cancer | RAS Wild TypeItaly
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Ludwig-Maximilians - University of MunichCharité Universitätsmedizin, Department of Hematology, Oncology and Tumor...Not yet recruitingMetastatic Colorectal Cancer | Multidisciplinary Communication | RAS Mutation | Secondary Intervention
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Beijing HospitalBethune Charitable FoundationRecruitingICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRCMetastatic Colorectal Cancer | MSS | RAS MutationChina
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Second Affiliated Hospital, School of Medicine,...Active, not recruitingMetastatic Colorectal Cancer | Microsatellite Stable | RAS MutationChina
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Fudan UniversityRecruitingMetastatic Colorectal Cancer | Microsatellite Stable Colorectal Carcinoma | RAS Mutation | CadonilimabChina
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EPS CorporationCompletedLiver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal CancerJapan
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Karen-Lise Garm SpindlerCompletedColorectal Cancer Metastatic | KRAS Gene Mutation | Circulating Tumor DNA | BRAF Gene Mutation | NRAS Gene Mutation | Epidermal Growth Factor Receptor InhibitorDenmark
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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AstraZenecaCompletedLocally Advanced or Metastatic EGFR Mutated NSCLC.Taiwan
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West China HospitalRecruitingBRAF V600E-mutated /MSS Metastatic Colorectal Cancer | Vemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal AntibodyChina
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European Organisation for Research and Treatment...Roche Pharma AG; AmgenTerminatedColorectal Cancer Metastatic | Liver Metastases | KRAS Wild Type Colorectal CancerFrance, Belgium, Austria, Netherlands, Spain, Switzerland
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University Health Network, TorontoBayer; AstraZeneca; Amgen; Applied Health Research Centre; Takeda Canada, Inc.; Programs...RecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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National Health Research Institutes, TaiwanKaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaboratorsUnknownColorectal Cancer | Drug Resistance | Mass Spectrometry | RAS-RAF Pathway DeregulationTaiwan
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Daiichi Sankyo, Inc.PlexxikonTerminatedV600-mutated BRAF Unresectable Melanoma | V600-mutated BRAF Metastatic Melanoma | Stage III or Stage IV Metastatic Melanoma That Has Not Been Previously Treated With a Selective BRAF InhibitorUnited States, Germany, France
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Institut de Cancérologie de la LoireSaint-Louis Hospital, Paris, France; Gustave Roussy, Cancer Campus, Grand ParisWithdrawnMetastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Head and Neck CancerFrance
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University of UtahTerminatedKRAS and NRAS Wild-type Colorectal CancerUnited States
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Mohammed M MilhemGenentech, Inc.TerminatedMelanoma | Metastatic Melanoma | BRAF-mutated Metastatic Melanoma | V600EBRAF-mutated Metastatic MelanomaUnited States
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Grupo Espanol Multidisciplinario del Cancer DigestivoRecruitingColorectal Cancer Metastatic | Liver Metastasis Colon CancerSpain
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Oncolytics BiotechMontefiore Medical CenterCompletedKRAS Mutant Metastatic Colorectal CancerUnited States
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Emory UniversityNational Cancer Institute (NCI); GlaxoSmithKline; National Institutes of Health...Active, not recruitingMicrosatellite Stable | Stage IV Colorectal Cancer AJCC v8 | RAS Wild Type | MSI-H Colorectal Cancer | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal CarcinomaUnited States
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University of UtahPfizerCompletedAdvanced KRAS Positive Metastatic Colorectal CancerUnited States
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Samsung Medical CenterCompletedColorectal CancerKorea, Republic of
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Jules Bordet InstituteCompletedMetastatic Colorectal Cancers | Metastatic Gastric Cancers | Metastatic Oesophageal Cancers | Metastatic Pancreatic Cancers | Metastatic Biliary Cancers | Metastatic Breast CancersBelgium
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Fundación de Investigación Biomédica - Hospital...Marcello Di MartinoCompletedMetastatic Colorectal Cancer | Metastatic Liver CancerSpain, United Kingdom, France
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Institut Investigacio Sanitaria Pere VirgiliInstitut Català d'Oncologia; Hospital Universitario Ramon y Cajal; Hospital Arnau... and other collaboratorsRecruitingMetastatic Colorectal Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Metastatic Prostate CancerSpain
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Centre Hospitalier Universitaire de NiceCompletedMetastatic Colorectal CancerFrance
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Chandrikha ChandrasekharanAstraZeneca; Biocompatibles UK LtdSuspendedMetastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon CancerUnited States
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Sierra Oncology, Inc.TerminatedRelapsed Metastatic KRAS-Mutated Non-Small Cell Lung CancerUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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Duke Cancer InstituteNational Cancer Institute (NCI)CompletedColorectal Cancer | Metastatic CancerUnited States
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Cardiff OncologyCompletedMetastatic Colorectal Cancer | KRAS Gene MutationUnited States
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Cardiff OncologyNo longer availableMetastatic Colorectal Cancer | KRAS Gene Mutation
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Orion Biotechnology Polska Sp. z o.o.Not yet recruitingMetastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
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GERCOR - Multidisciplinary Oncology Cooperative...Bristol-Myers SquibbActive, not recruitingMetastatic Cancer ColorectalFrance
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The First Affiliated Hospital of Zhengzhou UniversityBeiGene; Jiangsu Hengrui Pharmaceutical Co., Ltd.; RemeGen Co., Ltd.Not yet recruitingHER2-positive or Mutated Advanced Colorectal Cancer
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Assistance Publique - Hôpitaux de ParisNot yet recruitingMSI | dMMR Colorectal CancerFrance