Clinical Trials on Rectal Cancer in Germany

Total 5450 results

Ludwig-Maximilians - University of Munich

Unknown

Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial (CSAR)

Rectal Cancer | Rectal Neoplasms | Fecal Incontinence | Rectal Tumors

Germany
Johannes Gutenberg University Mainz

Completed

Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma (OCUM)

Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
Johannes Gutenberg University Mainz

Completed

Intraoperative Monitoring of the Pelvic Autonomic Nerves (NEUROS)

Rectal Cancer

Germany
University Hospital Tuebingen

Recruiting

Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy. (CAO/ARO/AIO-16)

Rectal Cancer | Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
Charite University, Berlin, Germany
ChirNet

Unknown

Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE) (SAVE)

Rectal Cancer

Germany
Technische Universität Dresden
Deutsches Krebsforschungszentrum (DKFZ)

Recruiting

Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery (CoBot2)

Rectum Cancer

Germany
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
University Hospital Tuebingen

Completed

Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer (HT01)

Hyperthermia | Rectal Cancer | Locally Advanced Rectal Cancer | Hyperthermic Radiochemotherapy | Hyperthermic Chemoradiotherapy | Deep Regional Hyperthermia

Germany
University Medical Center Goettingen
German Research Foundation

Active, not recruiting

Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC-II-IV, With a 5-Fluorouracil-based Standard Radiochemotherapy Followed by Total Mesorectal Excision. (TransValid-A)

Locally Advanced Rectal Cancer

Germany
University Hospital Heidelberg

Completed

Phase I/II Trial Evaluating Carbon Ion Radiotherapy for the Treatment of Recurrent Rectal Cancer (PANDORA)

Recurrent Rectal Cancer

Germany
Ludwig-Maximilians - University of Munich

Recruiting

Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer (NEOCARE)

Quality of Life | Chemoradiation | Rectal Cancer | Radiation Therapy

Germany
AIO-Studien-gGmbH

Completed

Comparison of Two Preemptive Treatment Strategies of Panitumumab Mediated Skin Toxicity and Assessment of QoL in Patient With Ras-wt Colorectal Cancer

Ras-wildtype Colorectal Cancer

Germany
Charite University, Berlin, Germany

Recruiting

Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS) (ART-02)

Head and Neck Cancer | Esophageal Cancer | NSCLC | Prostate Cancer | SCLC | Bladder Cancer | Cervix Cancer | Rectum Cancer | Other Carcinoma

Germany
iOMEDICO AG

Active, not recruiting

Registry Platform Colorectal Cancer (AZURITE)

Colorectal Cancer Metastatic

Germany
Charite University, Berlin, Germany

Not yet recruiting

Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors (HETERERO)

Sarcoma | Cervical Cancer | Esophageal Cancer | Rectal Cancer | Prostate Cancer | Neuroendocrine Tumors | Pancreas Cancer | Anal Cancer | Squamous Cell Carcinoma | Recurrent Cancer

Germany
MedInnovation GmbH
Helios Klinikum Berlin-Buch

Terminated

Validation of MMS Test for Cancer Monitoring (MMS-TM)

Melanoma | Sarcoma | Stomach Cancer | Colo-rectal Cancer

Germany
PD Dr. med. Volker Heinemann
MGO Ruhr-University Bochum (RUB)

Recruiting

Optimization of Individualized Therapy for CRCs With Secondary RESISTance Towards Anti-EGFR Targeted Therapy Using an Avatar Model (2016-003295-46)

Colo-rectal Cancer | RAS Wild-type | UICC III | UICC II + RF | UICC IV Curative Intent

Germany
German Breast Group
Celgene Corporation; Amgen

Completed

Denosumab as an add-on Neoadjuvant Treatment (GeparX) (GeparX)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
University Hospital Tuebingen

Recruiting

Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac

Breast Cancer | Head and Neck Cancer | Esophageal Cancer | Rectal Cancer | Prostate Cancer | Liver Cancer | Oligometastasis

Germany
German Breast Group
Roche Pharma AG; Celgene Corporation

Completed

Nanoparticle-based Paclitaxel vs Solvent-based Paclitaxel as Part of Neoadjuvant Chemotherapy for Early Breast Cancer (GeparSepto) (GeparSepto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
Juergen Debus

Recruiting

Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy (DILANA)

Anal Cancer

Germany
Ralf Hofheinz
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest; Deutsche... and other collaborators

Recruiting

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Economic Analysis of Robotic Rectal Resection in German Health Care System

Rectal Cancer

Germany
University of Ulm
Medac GmbH (Hamburg, Germany); Roche (Grenzach-Wyhlen, Germany)

Completed

Modulation of Adjuvant 5-FU by Folinic Acid and Interferon-alpha in Colon Cancer (FOGT1)

Rectal Cancer

Germany
Goethe University

Active, not recruiting

Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients (ACO/ARO/AIO-21)

Rectal Cancer

Germany
Heidelberg University

Terminated

Pilot Study for Evaluation of the Need for Protective Ileostomy After Low Anterior Resection Due to Rectal Cancer

Rectal Cancer

Germany
Ludwig-Maximilians - University of Munich

Recruiting

Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE) (LANACARE)

Quality of Life | Chemoradiation | Anal Cancer

Germany
Universitätsklinikum Hamburg-Eppendorf
Servier Affaires Médicales; Clinical Trial Center North (CTC North GmbH & Co...

Terminated

Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

Locally Advanced Rectal Cancer

Germany
Dr. Horst Schmidt Klinik GmbH

Recruiting

A Dual Tandem Study - SC vs. CAD-EYE vs. CAD-EYE With G-EYE

Adenoma | Colo-rectal Cancer

Germany
PD. Dr. med. Carola Seifart
German Federal Ministry of Education and Research; Philipps University Marburg... and other collaborators

Unknown

The "Hand-in-Hand Study": Improvement of Quality of Life in Palliative Cancer Patients Through Collaborative Advance Care Planning (COLAP)

Neoplasms | Advanced Cancer | End Stage Cancer

Germany
Neuropsychiatrischen Zentrums Hamburg-Altona
University of Hamburg-Eppendorf

Recruiting

Internet-delivered Psycho-oncological Support (ICBT_MAC)

Cancer

Germany
University Hospital Heidelberg
Health Economics and Health Care Management, Bielefeld University; Chair of... and other collaborators

Completed

Financial Effects of a Tumor Disease - Development and Validation of a Patient Reported Outcome Measure in Germany (FIAT)

Cancer

Germany
German Breast Group
Roche Pharma AG; Amgen; Teva Pharmaceuticals USA; Vifor Pharma

Completed

A Phase III Trial Comparing Two Dose-dense, Dose-intensified Approaches (ETC and PM(Cb)) for Neoadjuvant Treatment of Patients With High-risk Early Breast Cancer (GeparOcto)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Jena University Hospital

Recruiting

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer (PRIMO)

Radiotherapy | Neoadjuvant Treatment | Locally Advanced Rectal Carcinoma | Adaptive Treatment

Germany
AIO-Studien-gGmbH
Universitätsklinikum Hamburg-Eppendorf; Merck Serono GmbH, Germany; Pierre Fabre...

Recruiting

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer (NeoBRAF)

Colorectal Cancer | Colon Cancer | BRAF V600 Mutation | BRAF V600E | Localized Cancer

Germany
German Cancer Research Center
University of Leipzig; Heidelberg University; University Hospital Heidelberg; Children...

Completed

Exercise in Pediatric Cancer Patient Undergoing Anti-Cancer Treatment (ONKOKIDS-HD)

Childhood Cancer

Germany
Charite University, Berlin, Germany
Deutsche Krebshilfe e.V., Bonn (Germany)

Completed

Patient Empowerment and Risk-assessed Treatment to Improve Outcome in the Elderly After Onco-surgery (PERATECS)

Cancer

Germany
AIO-Studien-gGmbH

Completed

Avelumab and Cetuximab in Combination With FOLFOX in Patients With Previously Untreated Metastatic Colorectal Cancer - The Phase II AVETUX-CRC Trial. (AVETUX)

Metastatic Colorectal Cancer

Germany
Ludwig-Maximilians - University of Munich
Roche Pharma AG

Unknown

Cap+Bev vs Cap+Iri+Bev 1st-line Therapy in mCRC

Colorectal Cancer Metastatic

Germany
Dominik Paul Modest

Recruiting

Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Germany
Ludwig-Maximilians - University of Munich

Active, not recruiting

Metastatic Colorectal Cancer (RAS-wildtype) After Response to First-line Treatment With FOLFIR Plus Cetuximab (AIO-KRK-0114)

Metastatic Colorectal Cancer

Germany
Ludwig-Maximilians - University of Munich

Active, not recruiting

FOLFOXIRI Plus Cetuximab vs. FOLFOXIRI Plus Bevacizumab 1st-line in BRAF-mutated mCRC (AIO-KRK-0116)

Metastatic Colorectal Cancer

Germany
Servier Deutschland GmbH
iOMEDICO AG

Completed

Trifluridin/tipirACil in meTastatIc Colorectal Cancer (TACTIC)

Metastatic Colorectal Cancer

Germany
AIO-Studien-gGmbH
Bristol-Myers Squibb

Completed

A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer (RAMONA)

Esophageal Cancer | Gastrooesophageal Cancer | Oesophageal Cancer | GastroEsophageal Cancer | Esophageal Cancers NOS | Oesophageal Cancer Metastatic | Esophageal Cancer Metastatic | Oesophageal Cancer Nos

Germany
National Center for Tumor Diseases, Heidelberg

Completed

Neoadjuvant Radiochemotherapy Combined With Panitumumab in Locally Advanced KRAS Wild-type Rectal Cancer (NEOREC-1)

Rectal Cancer

Germany
Dr. Horst Schmidt Klinik GmbH

Completed

Clinical Value of G-EYE Colonoscopy in Daily Practice for Adenoma Detection and Time for Polyp Removal

Adenoma | Colo-rectal Cancer

Germany
Prof. Dr. med. Claus Rödel
Johann Wolfgang Goethe University Hospital; Deutsche Krebshilfe e.V., Bonn...

Completed

Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer (CAOAROAIO-12)

Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
AIO-Studien-gGmbH
Bayer; Institut für Klinisch-Onkologische Forschung (IKF) am Krankenhaus Nordwest...

Completed

Regorafenib in Combination With TAS-102 in Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy (REMETY)

Pretreated Metastatic Colorectal Cancer

Germany
Charite University, Berlin, Germany

Recruiting

Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With TAS-102 (Lonsurf) and Bevacizumab in Refractory Metastatic Colorectal Cancer (Live-RF)

Refractory Metastatic Colorectal Cancer

Germany
University Hospital Heidelberg
Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus Nordwest

Completed

Combined PD-1 and CCR5 Inhibition for the Treatment of Refractory Microsatellite Stable mCRC (PICCASSO)

Metastatic Colorectal Cancer | MSS

Germany

Clinical Trials on Rectal Cancer in Germany

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