Clinical Trials on Refractory Diabetic Macular Edema

Total 4235 results

University of Sydney
Allergan

Completed

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema (SwitchDMO)

Diabetes | Diabetic Retinopathy | Diabetic Macular Edema | Diabetic Macular Oedema

Australia
Shahid Beheshti University of Medical Sciences

Unknown

The Effect of Intravitreal Erythropoietin Injection for Refractive Diabetic Macular Edema

Refractory Diabetic Macular Edema

Iran, Islamic Republic of
University of Sydney

Completed

Intravitreal Triamcinolone for Clinically Significant Diabetic Macular Oedema That Persists After Laser Treatment (TDMO)

Diabetic Macular Oedema

Australia
Odense University Hospital
Moorfields Eye Hospital NHS Foundation Trust

Completed

Aflibercept anD navigateD vErsus coNvensional Laser in Diabetic macUlar edeMa (ADDENDUM)

Diabetic Macular Oedema

Denmark
University of Sydney

Completed

Open Label Extension of a Clinical Trial of Intravitreal Triamcinolone for Diabetic Macular Oedema-TDMX Study

Diabetic Macular Oedema

Australia
University of Sydney
University of Melbourne; The University of Western Australia; Marsden Eye Specialists

Completed

A Multicentre Randomised Clinical Trial of Laser Treatment Plus Intravitreal Triamcinolone for Diabetic Macular Oedema

Diabetic Macular Oedema

Australia
Manchester University NHS Foundation Trust
Topcon Corporation; Optos, PLC

Withdrawn

Sub-threshold Photocoagulation of Diabetic Macular Oedema (MEM)

Diabetic Macular Oedema

United Kingdom
Allergan

Completed

Study of OZURDEX® in the Treatment of Diabetic Macular Oedema (DME) in Australia - The AUSSIEDEX Study

Diabetic Macular Oedema

Australia
University of Oxford
Pfizer

Completed

Intravitreal Macugen for Ischaemic Diabetic Macular Oedema (MIDME)

Diabetic Macular Oedema

United Kingdom
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.
Fountain Medical Development Co., Ltd.

Recruiting

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Type 2 Diabetes With Diabetic Macular Edema | Type 1 Diabetes With Diabetic Macular Edema

China
Novartis Pharmaceuticals

Completed

Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment (RELIGHT)

Diabetic Retinopathy | Macular Oedema

United Kingdom
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Active, not recruiting

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
Cairo University

Completed

Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema

Diabetic Retinopathy | Macula Edema

Egypt
Indonesia University
Bayer

Completed

Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection

Diabetic Retinopathy | Diabetic Macular Edema | Clinically Significant Macular Edema

Indonesia
Targeted Therapy Technologies, LLC

Unknown

A Phase I Study of Episcleral Dexamethasone for Treatment of Macular Edema

Refractory Diabetic Macular Edema

United States
Evolucare Technologies
Assistance Publique - Hôpitaux de Paris; Slb Pharma; BPIfrance

Recruiting

OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases (OPHTAI-EVAL)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Age-related Maculopathy

France
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Oxurion

Completed

A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States, France, United Kingdom, Spain, Germany, Italy, Slovakia, Czechia
Fovea Pharmaceuticals SA

Completed

Safety and Efficacy Study of Topical Administration of FOV2304 (High Dose or Low Dose) for the Treatment of Center-involving Clinically Significant Macular Edema Associated With Diabetic Retinopathy

Diabetic Macular Edema

United States, Australia, Belgium, Czech Republic, France, Germany, Israel, Italy, Poland, Spain
Asociación para Evitar la Ceguera en México

Completed

Unilateral Bevacizumab for Bilateral Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Mexico
Mayo Clinic

Completed

International Consortium Investigating Early Vitrectomy in Diabetic Macular Edema Patients (ICV-DME)

Diabetes With Diabetic Retinopathy With Macular Edema

United States
Cairo University

Terminated

Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema (REBEL)

Diabetic Retinopathy | Diabetic Macular Edema | Vascular Endothelial Growth Factor Overexpression | Macular Ischemia

Egypt
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China
Aviceda Therapeutics, Inc.

Terminated

A Phase 2 Study of Intravitreal AVD-104 in Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States
Oxurion

Terminated

A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. (INTEGRAL)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

Latvia, Lithuania, United States, Hungary, Estonia
Duke University

Completed

Imaging Parameters and DME Treatment Response

Diabetic Retinopathy | Diabetic Macular Edema

United States
Lions Eye Institute, Perth, Western Australia
Allergan; Lions Outback Vision

Completed

Intravitreal Dexamethasone vs Bevacizumab in Aboriginal People With DMO (OASIS)

Diabetic Retinopathy | Diabetic Macular Edema

Australia
Hospital Juarez de Mexico

Unknown

Efficacy of Dorzolamide as an Adjuvant After Focal Photocoagulation in Clinically Significant Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Mexico
Rocky Mountain Retina Consultants
Genentech, Inc.

Completed

Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States
Valley Retina Institute

Completed

Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study (PRESERVE)

Diabetic Macular Edema

United States
ThromboGenics

Completed

A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

Evaluation of Vitrectomy for Diabetic Macular Edema (Vitrectomy-D)

Diabetic Retinopathy | Diabetic Macular Edema

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; Allergan

Completed

Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema (LRT for DME)

Diabetic Retinopathy | Diabetic Macular Edema

United States
Bernardete Pessoa MD

Completed

Intravitreal Ranibizumab or Aflibercept After Bevacizumab in Diabetic Macular Edema (SWITCH)

Diabetic Retinopathy | Diabetic Macular Edema
ThromboGenics

Completed

A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States
Queen's University, Belfast

Completed

A Systematic Study of Retinal Structure and Function in Diabetic Macular Oedema

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United Kingdom
National Eye Institute (NEI)

Terminated

Evaluation of Single Nucleotide Polymorphisms (SNPs) in Patients With and Without Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States
National Eye Institute (NEI)

Completed

Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation

Diabetic Retinopathy | Diabetic Macular Edema | DME

United States
Heidelberg University

Unknown

Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Germany
Ziv Hospital

Unknown

Comparison of Initial Treatment in With Laser Grid in Diabetic Macular Edema to Intra Vitreal Avastin Injections

Diabetic Macular Edema | Diabetus Mellitus

Israel
PolyPhotonix Medical

Terminated

Noctura400 Treatment for Diabetic Retinopathy (CANDLE) (CANDLE)

Diabetic Macular Oedema

United Kingdom
Joslin Diabetes Center
Juvenile Diabetes Research Foundation; Genentech, Inc.; Optovue

Completed

OCT Screening for Diabetic Macular Edema at Primary Diabetes Care Visits (DME FOUND)

Diabetes | Diabetic Retinopathy | Diabetic Macular Edema

United States
Hospital Juarez de Mexico

Completed

Contrast Sensitivity and Diabetic Macular Edema

DIABETES MELLITUS | DIABETIC RETINOPATHY | MACULAR EDEMA

Mexico
Xinhua Hospital, Shanghai Jiao Tong University...
Novartis

Unknown

Pre-vitrectomy Intravitreal Ranibizumab for Patients With Proliferative Diabetic Retinopathy Combined With Diabetic Macular Edema

Diabetic Macular Edema | Proliferative Diabetic Retinopathy

China
Lawson Health Research Institute
Pfizer

Completed

Effect of Macugen(Pegaptanib)on Surgical Outcomes and VEGF Levels in Diabetic Patients With PDR (Diabetic Retinopathy or CSDME (Macular Edema) (PEGAP001)

Diabetic Macular Edema | Proliferative Diabetic Retinopathy

Canada
Eye & ENT Hospital of Fudan University

Unknown

Prophylactic Effect of Conbercept Intravitreal Injection at the Conclusion of Cataract Surgery for Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Cataract Diabetic
Marsden Eye Specialists

Completed

To Evaluate the Comparative Efficacy of Lucentis (Ranibizumab) 0.5mg Intravitreal Injection in Patients With Diabetic Macular Oedema (DME) With Well Controlled and Poorly Controlled Diabetes Mellitus (CONTROL)

Diabetic Macular Oedema

Australia
Santen SAS

Completed

Safety and Tolerability of NOVA63035 "Corticosteroid" in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy

Diabetic Macular Edema

United States
Pfizer

Completed

Study To Evaluate Safety And Tolerability Of Pegaptanib Sodium In Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Anti- VGF Inhibitor

Spain, United Kingdom, Finland, Sweden
University of Sydney

Completed

Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema (NIRD)

Diabetic Macular Oedema

Australia

Clinical Trials on Refractory Diabetic Macular Edema

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovakia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations